Biochemical pathways: an atlas of biochemistry and molecular biology
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley
2012
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 398 S. Ill., graph. Darst. |
| ISBN: | 9780470146842 |
Internformat
MARC
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| 245 | 1 | 0 | |a Biochemical pathways |b an atlas of biochemistry and molecular biology |c ed. by Gerhard Michal ... |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Hoboken, NJ |b Wiley |c 2012 | |
| 300 | |a XI, 398 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
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Datensatz im Suchindex
| _version_ | 1804143488046989312 |
|---|---|
| adam_text | Contents
Preface
to the Second Edition IX
From the Preface to the First Edition X
Contributors XI
.
Introduction and General Aspects
1
Gerhard
Michal
and
Dietmar Schomburg
1.1
Organization of This Book
1
1.1.1
Conventions Used in This Book
3
1.1.2
Common Abbreviations
3
1.2
Carbohydrate Chemistry and Structure
4
1.2.1
Structure and Classification
4
1.2.2
Glycosidic Bonds
5
1.3
Amino
Acid Chemistry and Structure
5
1.3.1
Structure and Classification
6
1.3.2
Peptide
Bonds
6
1.4
Lipid
Chemistry and Structure
6
1.4.1
Fatty acids
6
.4.2
Acylglycerols and Derivatives
7
.4.3
Waxes
7
.4.4
Glycerophospholipids
7
.4.5
Plasmalogens
7
.4.6
Sphingolipids
7
.4.7
Steroids
8
1.4.8
Lipoproteins
8
1.5
Phy sico-Chemical Aspects of Biochemical
Processess
1.5.1
Energetics of Chemical Reactions
8
1.5.2
Redox
Reactions
9
1.5.3
Transport Through Membranes
9
1.5.4
Enzyme Kinetics
10
!
The Cell and Its Contents
14
Gerhard
Michal
and
Dietmar
Schomburg
2.1
Classification of Living Organisms
14
2.2
2.2.1
2.2.2
2.2.3
2.2.4
2.3
2.3.1
2.3.2
2.4
2.4.1
2.4.2
2.4.3
2.4.4
2.4.5
2.5
2.5.1
2.5.2
2.5.3
2.6
2.6.1
2.6.2
2.6.3
2.6.4
2.7
2.7.1
2.7.2
2.7.3
Structure of Cells
Í4
Prokaryotic Cells
14
General Characteristics of Eukaryotic Cells
15
Special Structures of Plant Cells
17
Special Structures of Animal Cells
18
Protein Structure and Function
18
Levels of Organization
19
Protein Function
21
Enzymes
21
Catalytic Mechanism
21
Isoenzymes
23
Multienzyme Complexes
23
Reaction Rate
23
Classification of Enzymes
23
Regulation of the Enzyme Activity
24
Regulation of the Quantity of Enzymes
24
Regulation of the Activity of Enzymes
24
Site of Regulation
26
Nucleic Acid Structure
26
Components of Nucleic Acids
26
Properties of
RNA
Chains
27
Properties of
DNA
Chains
27
Compaction Levels of
DNA
Chains
28
Genetic Code and the Flow of Information
30
From
DNA
to
RNA
30
From Nucleic Acids to Proteins-The Genetic Code
30
Influence of Enors
31
2.8
Polymeric Carbohydrates
31
2.8.1
Polymeric Carbohydrates in Energy Storage
31
2.8.2
Polymeric Carbohydrates as Structural Elements
32
2.9
Glycosylated Proteins and Peptides
32
2.9.1
Glycoproteins
33
2.9.2
Proteoglycans
33
2.9.3
Peptidoglycans
35
2.10
Lipid
Aggregates and Membranes
35
!
Metabolism
37
3.1
Carbohydrate Metabolism and Citrate Cycle
37
Robbe Wiinschiers
3.1.1
Glycolysis and Gluconeogenesis
37
3.1.2
Polysaccharide Metabolism
42
3.1.3
Pyruvate Turnover and Acetyl-Coenzyme A
46
3.1.4
Di-
and Oligosaccharides
48
3.1.5
Metabolism of Hexose Derivatives
48
3.1.6
Pentose Metabolism
51
3.1.7
Amino
Sugars
54
3.1.8
Citrate Cycle
55
3.1.9
Glyoxylate Metabolism
57
3.2
Amino
Acids and Derivatives
58
Robbe Wiinschiers
3.2.1
Nitrogen Fixation and Metabolism
58
3.2.2
Glutamate,
Glutaminę,
Alanine,
Aspartate, Asparagine and
Ammonia Turnover
59
3.2.3
Proline
and Hydroxyproline
62
3.2.4
Serine
and
Glycine
62
3.2.5
Lysine,
Threonine, Methionine,
Cysteine
and
Sulfur Metabolism
65
3.2.6
Leucine, Isoleucine and
Valine
72
3.2.7
Phenylalanine, Tyrosine, Tryptophan and
Derivatives
74
3.2.8
Histidine
79
3.2.9
Urea Cycle,
Arginine
and Associated
Reactions
80
3.3
Tetrapyrroles
82
Martina
Jahn
and Dieter
Jahn
3.3.1
Pathways for the Biosynthesis of
Tetrapyrroles
82
3.3.2
Heme
and Cytochrome Biosynthesis
86
3.3.3
Linear Tetrapyrroles
87
3.3.4
Biosynthesis of Chlorophylls
90
3.3.5
Biosynthesis of Cobalamins
91
3.3.6
Siroheme Biosynthesis
91
3.4
Lipids and Glycolipids
93
Robbe Wiinschiers
3.4.1
Fatty Acids and
Acyl-CoA 93
3.4.2
Triacylglycerols
(Triglycérides)
98
3.4.3
Phospholipids
100
3.4.4
Glycolipids
104
3.5
Steroids and Isoprenoids
107
Robbe Wiinschiers
3.5.1
Cholesterol
107
3.5.2
Hopanoids, Steroids of Plants and
Insects
110
3.5.3
Isoprenoids
111
3.5.4
Steroid Hormones
114
3.5.5
Gestagen
115
3.5.6
Androgens
116
3.5.7
Estrogens
117
3.5.8
Corticosteroids
119
3.5.9
Bile Acids
121
VI
Contents
3.6
Nucleotides
and Nucleosides
124
Robbe Wünschiers
3.6.1 Purine Nucleotides and Nucleosides 124
3.6.2 Pyrimidine Nucleotides and Nucleosides 130
3.7 Cofactors and Vitamins 133
¡da Schomburg
3.7.1 Retinol (Vitamin A) 133
3.7.2 Thiamin (Vitamin B,) 134
3.7.3
Riboflavin
(Vitamin B,), FMN and FAD 135
3.7.4 Pyridoxine (Vitamin Bj) 136
3.7.5 Cobalamin (Coenzyme Bp, Vitamin B„) 137
3.7.6
Folate
and Pterines 138
3.7.7 Pantothenate, Coenzyme
A and Acyl Carrier
Protein (ACP) 141
3.7.8 Biotin 141
3.7.9 Nicotinate,
NAD* and NADP*
143
3.7.10 Ascorbate (Vitamin C) 145
3.7.11
Calciferol
(Vitamin D) 146
3.7.12 Tocopherol (Vitamin E) 148
3.7.13 Phylloquinone and Menaquinone (Vitamin K) 148
3.7.14
Other Compounds
149
3.8
Nucleic Acid Metabolism in Bacteria
149
Susanne Peifer
and
Elmar Heimle
3.8.1
Bacterial
DNA
Replication
149
3.8.2
Bacterial
DNA
Repair
151
3.8.3
Degradation of Nucleic Acids
156
3.9
Nucleic Acid Metabolism in Eukarya
157
Helmut Burtscher
3.9.1
Eukaryotic
DNA
Replication
157
3.9.2
Eukaryotic
DNA
Repair
162
3.10
Special Bacterial Metabolism and Biosynthesis of
Antimicrobials
164
Julia
Garbe, Annika
Steen
and Max
Schobert
3.10.1
Bacterial Envelope
164
3.10.2
Bacterial Protein Export across the Cytoplasmie Membrane
166
3.10.3
Protein Transport across the Outer Membrane of
Gram-Negative Bacteria
167
3.10.4
Bacterial Transport Systems
168
3.10.5
Bacterial Fermentations
169
3. ! 0.6
Anaerobic Respiration
173
3.10.7
Chemolithotrophy
175
3.10.8
Quinoenzymes, Alkane and Methane Oxidation
178
3.10.9
Antibiotics
179
3.11
Electron Transfer Reactions and Oxidative
Phosphorylation
183
Martina
Jahn
and Dieter
Jahn
3.11.1
General Principles
183
3.11.2
Different types ofelectron transport chains
183
3.11.3
The Energetic Basis of the Oxidative Phosphorylation
183
3.11.4
Electron Transport System in Mitochondria and Bacteria
184
3.12
Photosynthesis
188
Dieter Oesterhelt and Josef Wachtveitl
3.12.1
Light Reaction
188
3.12.2
Dark Reactions
192
3.13
3.13.1
3.13.2
3.13.3
4.1
4.1.1
4.1.2
Plant Secondary Metabolism
193
Antje
Chang
Phenolics
194
Terpenoids
198
Nitrogen-containing Secondary Metabolites
201
Protein Biosynthesis, Modifications and
Degradation
210
Protein Synthesis in Bacteria
210
Martina
Jahn
and Dieter
Jahn
Bacterial Transcription
210
Regulation of Bacterial Gene Expression
212
4.1.3
4.1.4
4.2
4.2.1
4.2.2
4.2.3
4.2.4
4.2.5
4.3
4.3.1
4.3.2
4.3.3
4.3.4
4.3.5
4.3.6
4.4
4.4.1
4.4.2
4.4.3
4.5
4.5.1
4.5.2
4.5.3
4.5.4
4.5.5
4.5.6
4.5.7
5.1
5.1.1
5.1.2
5.2
5.2.1
5.3
5.3.1
5.4
5.4.1
6.1
6.1.1
6.1.2
6.1.3
6.1.4
6.1.5
6.1.6
6.2
6.2.1
6.2.2
6.2.3
6.2.4
6.2.5
Bacterial Protein Synthesis
214
Degradation of Nucleic Acids
217
Protein Biosynthesis in Eukarya
219
Robbe Wünschiers
Eukaryotic Transcription
219
Regulation of Eukaryotic Transcription
226
Eukaryotic Translation
228
Translationa! Regulation
231
mRNA Degradation
231
Cell Cycle in Eukarya
232
Stefan
Ries
Core Components of the Cell Cycle Machinery
232
Cell Cycle Regulation in Yeast
234
G( to
S
Transition in Mammalian Cells
234
G, to
M
Transition in Mammalian Cells
235
Mitosis in Mammalian Cells
235
Cell Cycle Checkpoints
236
Posttranslational Modification of Proteins
238
Robbe Wünschiers
Protein Processing in the Endoplasmic Reticulum
238
Glycosylation Reactions in the Golgi Apparatus
241
Terminal Carbohydrate Structures of
Glycoconjugates
243
Protein Folding, Transport/Targeting and
Degradation
244
Petra Dersch
Folding of Proteins
244
Vesicular Transport and Secretion of Proteins
248
Protein Transport into the Nucleus
249
Protein Transport into Mitochondria
252
Protein Transport into Chloroplasts
254
Protein Degradation
256
Protein Degradation by the Ubiquitin-Proteasome
System
258
Viruses
261
Klaus Klumpp
General Characteristics of Viruses
261
Genomic Characteristics of Viruses
261
Structure
263
DNA
Viruses
Papillomavirus
264
264
RNA
Viruses
267
Hepatitis
С
Virus
267
Retroviruses
268
Human Immunodeficiency Virus
(HIV) 268
Transport
272
Transport Through Membranes
272
Wilhelm Just
Systems of Eukaryotic Membrane Passage
272
Channels/Pores
272
Solute Carriers
276
Primary Active Transport Systems
277
Import by Endocytosis and Pinocytosis
278
The Cytoskeleton as Means for Intracellular Transport and
Cellular Movements in Eukarya
278
Transport of Lipids in Plasma
279
Horst Klima
Apolipoproteins
(Apo)
279
Plasma Lipoprotein Metabolism
279
Lipid
Transport Proteins
281
Lipoprotein Receptors
281
Lipid
Metabolic Disorders
282
Contents
VII
6.3
Oxygen Transport by Hemoglobin
282
Gerhard
Michał
6.3.1
Biosynthesis and Properties of Hemoglobin and
Myoglobin
282
6.3.2
Oxygen Binding to Hemo- and Myoglobin
283
6.3.3
Hemoglobin Diseases in Humans
285
Signal TYansduction and Cellular
Communication
286
Gerhard Niederfellner
7.1
Intercellular Signal Transmission by Hormones
286
7.1.1
General Characteristics of Hormones
286
.2
General Characteristics of Receptors
286
.3
Insulin and Glucagon
287
.4
Epinephrine and Norepinephrine (Catecholamines)
287
.5
Hypothalamus-Anterior Pituitary Hormone System
287
.6
Placental Hormones
291
7.1.7
Hormones Regulating the Extracellular Ca*+, Mg++ and
Phosphate Concentrations
292
7.1.8
Hormones Regulating the Na* Concentration and the Water
Balance
292
7.1.9
Hormones of the Gastrointestinal Tract
293
7.2
Nerve Conduction and Synaptic Transmission
294
7.2.1
Membrane Potential
294
7.2.2
Conduction of the Action Potential along the Axon
294
7.2.3
Transmitter Gated Signalling at the Synapse
294
7.2.4
Voltage Gated Signalling at the Synapse
296
7.2.5
Postsynaptic Receptors
296
7.2.6
Axonal Transport
296
7.3
Principles of Intracellular Communication
296
7.4
Receptors Coupled to Heterotrimeric G-Proteins
299
7.4.1
Mechanism of Heterotrimeric G-Protein Action
300
7.4.2
cAMP Metabolism, Activation of Adenylate Cyclase and
Protein Kinase A
302
7.4.3
Activation of Phospholipase
С
and Protein Kinase
С
302
7.4.4
Metabolic Role of lnositol Phosphates and Ca
303
7.4.5
Muscle Contraction
305
7.4.6
Visual Process
307
7.4.7
Olfactory and Gustatory Processes
308
7.4.8
Arachidonate Metabolism and Eicosanoids
309
7.5
Receptors Acting Through Tyrosine Kinases
311
7.5.1
Regulatory Factors for Ceil Growth and Function
311
7.5.2
Components of the Signal Cascades
3
1
1
7.5.3
Receptor Tyrosine Kinases
312
7.5.4.
Tyrosine Kinase-Associated Receptors (TKaR)
315
7.6
Programmed Cell Death (Apoptosis)
319
7.7
Receptors for Steroid and Thyroid Hormones, for
Retinoids and Vitamin
D
321
7.8
Cyclic GMP Dependent Pathways and Effects of
Nitric Oxide (NO)
322
7.8.1
Membrane Bound Guanylate Cyclases
323
7.8.2
Soluble Guanylate Cyclases and Their Activation by
Nitric Oxide (NO)
323
7.8.3
Protein Kinase
G
323
Immune System
325
Ernst Peter
Rieber
і
Л
Components of the Immune System
325
8.1.1
Innate,
Non
Adaptive Immune System
325
8.1.2
Specific, Adaptive Immune System
328
8.1.3
8.1.4
8.1.5
8.1.6
8.1.7
8.1.8
8.2.1
8.2.2
8.2.3
8.2.4
8.2.5
8.2.6
8.2.7
8.2.8
8.3
8.3.1
8.3.2
8.4
9.1
9.2
9.2.1
9.2.2
9.2.3
9.3
9.3.1
9.3.2
9.3.3
9.3.4
9.3.5
9.5
9.5.1
9.5.2
10
10.1
10.2
10.3
Development and Maturation of the Cellular
Components
328
Antigen Receptor of
В
Lymphocytes,
Antibodies
330
Complement System
334
Antigen Receptor of
Τ
Lymphocytes
336
Antigen Presentation by MHC Molecules
337
Cytokines, Chemokines and Receptors
338
Generation of a Specific Immune
Response
343
Activation of
Τ
Cells
343
CD4*
Τ
Effector Cells, Regulation of the Immune
Response
344
Activation of
В
Cells
345
Lymphocyte Circulation and Generation of Cellular and
Humoral Immune Responses in Lymphoid Tissue
345
Cellular Cytotoxicity and Apoptosis
347
Interactions between the Immune System and the
Neuroendocrine
System
350
Immunological Tolerance
350
Induction of Specific Immune Responses against
Pathogens
351
Pathologic Immune responses
352
IgE-Mediated Hypersensitivity of the
Immediate Type
352
Autoimmunity
353
Adhesion of Leukocytes
Anton
Haselbeck
354
Blood Coagulation and Fibrinolysis
Peter
Müller
Hemostasis
357
357
Initial Reactions
358
Reactions Initiated by the Tissue Factor
Contact Activation
358
Generation of Binding Surfaces
358
Coagulation Propagation and Control
Requirements for Protease Activity
359
Pathways Leading to Thrombin
359
Key Events
359
Controlled Propagation
360
Generation of Fibrin
36
1
358
359
9.4
Platelets (Thrombocytes)
362
Fibrinolysis
364
Pathways of Plasminogen Activation
364
Control of Fibrinolysis
365
Biochemical Networks, Bioinformatics and Systems
Biology
366
Dietmar Schomburg
Systems Biology and Networks
366
Modeling of Metabolic Fluxes
366
Biochemical Pathways Information
Resources
366
10.3.1
Overview
366
10.3.2
Detailed Description of Some Databases
367
Index
374
|
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV036797397 |
| classification_rvk | VK 8500 WD 4000 WD 4010 WD 5000 |
| classification_tum | BIO 220f CHE 800f |
| ctrlnum | (OCoLC)699708758 (DE-599)BSZ327332425 |
| dewey-full | 572.84 572 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.84 572 |
| dewey-search | 572.84 572 |
| dewey-sort | 3572.84 |
| dewey-tens | 570 - Biology |
| discipline | Chemie / Pharmazie Biologie Chemie |
| edition | 2. ed. |
| format | Book |
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| genre | (DE-588)4151278-9 Einführung gnd-content |
| genre_facet | Einführung |
| id | DE-604.BV036797397 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:48:27Z |
| institution | BVB |
| isbn | 9780470146842 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-020713678 |
| oclc_num | 699708758 |
| open_access_boolean | |
| owner | DE-91S DE-BY-TUM DE-20 DE-M49 DE-BY-TUM DE-11 DE-355 DE-BY-UBR DE-91G DE-BY-TUM DE-19 DE-BY-UBM DE-188 DE-92 |
| owner_facet | DE-91S DE-BY-TUM DE-20 DE-M49 DE-BY-TUM DE-11 DE-355 DE-BY-UBR DE-91G DE-BY-TUM DE-19 DE-BY-UBM DE-188 DE-92 |
| physical | XI, 398 S. Ill., graph. Darst. |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Wiley |
| record_format | marc |
| spelling | Biochemical pathways an atlas of biochemistry and molecular biology ed. by Gerhard Michal ... 2. ed. Hoboken, NJ Wiley 2012 XI, 398 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Atlas (DE-588)4143303-8 gnd rswk-swf Stoffwechselweg (DE-588)4240505-1 gnd rswk-swf Biochemie (DE-588)4006777-4 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Stoffwechsel (DE-588)4057699-1 gnd rswk-swf (DE-588)4151278-9 Einführung gnd-content Biochemie (DE-588)4006777-4 s Stoffwechselweg (DE-588)4240505-1 s Atlas (DE-588)4143303-8 s DE-604 Molekularbiologie (DE-588)4039983-7 s Stoffwechsel (DE-588)4057699-1 s 1\p DE-604 Michal, Gerhard Sonstige oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020713678&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Biochemical pathways an atlas of biochemistry and molecular biology Atlas (DE-588)4143303-8 gnd Stoffwechselweg (DE-588)4240505-1 gnd Biochemie (DE-588)4006777-4 gnd Molekularbiologie (DE-588)4039983-7 gnd Stoffwechsel (DE-588)4057699-1 gnd |
| subject_GND | (DE-588)4143303-8 (DE-588)4240505-1 (DE-588)4006777-4 (DE-588)4039983-7 (DE-588)4057699-1 (DE-588)4151278-9 |
| title | Biochemical pathways an atlas of biochemistry and molecular biology |
| title_auth | Biochemical pathways an atlas of biochemistry and molecular biology |
| title_exact_search | Biochemical pathways an atlas of biochemistry and molecular biology |
| title_full | Biochemical pathways an atlas of biochemistry and molecular biology ed. by Gerhard Michal ... |
| title_fullStr | Biochemical pathways an atlas of biochemistry and molecular biology ed. by Gerhard Michal ... |
| title_full_unstemmed | Biochemical pathways an atlas of biochemistry and molecular biology ed. by Gerhard Michal ... |
| title_short | Biochemical pathways |
| title_sort | biochemical pathways an atlas of biochemistry and molecular biology |
| title_sub | an atlas of biochemistry and molecular biology |
| topic | Atlas (DE-588)4143303-8 gnd Stoffwechselweg (DE-588)4240505-1 gnd Biochemie (DE-588)4006777-4 gnd Molekularbiologie (DE-588)4039983-7 gnd Stoffwechsel (DE-588)4057699-1 gnd |
| topic_facet | Atlas Stoffwechselweg Biochemie Molekularbiologie Stoffwechsel Einführung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020713678&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT michalgerhard biochemicalpathwaysanatlasofbiochemistryandmolecularbiology |