Protein folding and metal ions: mechanisms, biology and disease
"Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biolo...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boca Raton [u.a.]
CRC Press
2011
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | "Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XIV, 294 S. Ill., graph. Darst. |
| ISBN: | 9781439809648 |
Internformat
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| 500 | |a Includes bibliographical references and index | ||
| 520 | 1 | |a "Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher | |
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Datensatz im Suchindex
| _version_ | 1804143439423471616 |
|---|---|
| adam_text | Titel: Protein folding and metal ions
Autor: Gomes, Cláudio M.
Jahr: 2011
Contents
Preface......................................................................................................................vii
Acknowledgments.....................................................................................................ix
About the Editors......................................................................................................xi
Contributors...........................................................................................................xiii
SECTION I Folding and Stability of Metalloproteins
Chapter 1 Metal Ions, Protein Folding, and Conformational States:
An Introduction....................................................................................3
Claudio M. Gomes and Pernilla Wittung-Stafshede
Chapter 2 The Folding Mechanism of c-Type Cytochromes..............................13
Carlo Travaglini-Allocatelli, Stefano Gianni,
and Maurizio Brunori
Chapter 3 The Mechanism of Cytochrome c Folding: Early Events and
Kinetic Intermediates.........................................................................37
Eefei Chen, Robert A. Goldbeck, and David S. Kliger
Chapter 4 Stability and Folding of Copper-Binding Proteins.............................61
Irina Pozdnyakova and Pernilla Wittung-Stafshede
Chapter 5 Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability...........81
Sonia S. Leal and Claudio M. Gomes
Chapter 6 Folding and Stability of Myoglobins and Hemoglobins.....................97
David S. Culbertson and John S. Olson
SECTION II Mechanisms of Metal Transporters
and Assembly
Chapter 7 Frataxin: An Unusual Metal-Binding Protein in Search
of a Function.....................................................................................125
Annalisa Pastore
v
vi Contents
Chapter 8 Mechanism of Human Copper Transporter
Wilson s Disease Protein..................................................................145
Amanda Barry, Zara Akram, and Svetlana Lutsenko
SECTION III Metal Ions, Protein Conformation,
and Disease
Chapter 9 oc-Synuclein and Metals...................................................................169
Aaron Santner and Vladimir N. Uversky
Chapter 10 Zinc and p53 Misfolding..................................................................193
James S. Butler and Stewart N. Loh
Chapter 11 The Octarepeat Domain of the Prion Protein and Its Role
in Metal Ion Coordination and Disease...........................................209
Glenn L. Millhauser
SECTION IV Metalloprotein Design, Simulation,
and Models
Chapter 12 Metallopeptides as Tools to Understand Metalloprotein
Folding and Stability........................................................................227
Brian R. Gibney
Chapter 13 The Folding Landscapes of Metalloproteins....................................247
Patrick Weinkam and Peter G. Wolynes
Appendix...............................................................................................................275
Index......................................................................................................................287
|
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| isbn | 9781439809648 |
| language | English |
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| spelling | Protein folding and metal ions mechanisms, biology and disease ed. by Cláudio M. Gomes ... Boca Raton [u.a.] CRC Press 2011 XIV, 294 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index "Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher Proteinfaltung (DE-588)4324567-5 gnd rswk-swf Metallproteide (DE-588)4169623-2 gnd rswk-swf Metalloproteins Protein folding Metallochaperones Protein Conformation Protein Folding Protein Stability (DE-588)4143413-4 Aufsatzsammlung gnd-content Proteinfaltung (DE-588)4324567-5 s Metallproteide (DE-588)4169623-2 s DE-604 Gomes, Cláudio M. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020685949&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Protein folding and metal ions mechanisms, biology and disease Proteinfaltung (DE-588)4324567-5 gnd Metallproteide (DE-588)4169623-2 gnd |
| subject_GND | (DE-588)4324567-5 (DE-588)4169623-2 (DE-588)4143413-4 |
| title | Protein folding and metal ions mechanisms, biology and disease |
| title_auth | Protein folding and metal ions mechanisms, biology and disease |
| title_exact_search | Protein folding and metal ions mechanisms, biology and disease |
| title_full | Protein folding and metal ions mechanisms, biology and disease ed. by Cláudio M. Gomes ... |
| title_fullStr | Protein folding and metal ions mechanisms, biology and disease ed. by Cláudio M. Gomes ... |
| title_full_unstemmed | Protein folding and metal ions mechanisms, biology and disease ed. by Cláudio M. Gomes ... |
| title_short | Protein folding and metal ions |
| title_sort | protein folding and metal ions mechanisms biology and disease |
| title_sub | mechanisms, biology and disease |
| topic | Proteinfaltung (DE-588)4324567-5 gnd Metallproteide (DE-588)4169623-2 gnd |
| topic_facet | Proteinfaltung Metallproteide Aufsatzsammlung |
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