Introduction to pharmacokinetics and pharmacodynamics: the quantitative basis of drug therapy
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Philadelphia
Lippincott, Williams & Wilkins
2010
|
| Ausgabe: | [Nachdr.] |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 326 S. Ill., graph. Darst. |
| ISBN: | 0781751497 9780781751490 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV036702945 | ||
| 003 | DE-604 | ||
| 005 | 20131010 | ||
| 007 | t | ||
| 008 | 101005s2010 ad|| |||| 00||| eng d | ||
| 020 | |a 0781751497 |9 0-7817-5149-7 | ||
| 020 | |a 9780781751490 |9 978-0-7817-5149-0 | ||
| 035 | |a (OCoLC)705879793 | ||
| 035 | |a (DE-599)BVBBV036702945 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-20 |a DE-188 | ||
| 084 | |a VX 8550 |0 (DE-625)147830:253 |2 rvk | ||
| 100 | 1 | |a Tozer, Thomas N. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Introduction to pharmacokinetics and pharmacodynamics |b the quantitative basis of drug therapy |c Thomas N. Tozer ; Malcolm Rowland |
| 250 | |a [Nachdr.] | ||
| 264 | 1 | |a Philadelphia |b Lippincott, Williams & Wilkins |c 2010 | |
| 300 | |a X, 326 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Pharmacokinetics | |
| 650 | 4 | |a Drugs / Physiological effect | |
| 650 | 4 | |a Dose-Response Relationship, Drug | |
| 650 | 4 | |a Drug Therapy / methods | |
| 650 | 4 | |a Pharmaceutical Preparations / administration & dosage | |
| 650 | 4 | |a Pharmacocinétique | |
| 650 | 4 | |a Médicaments / Effets physiologiques | |
| 650 | 0 | 7 | |a Pharmakokinetik |0 (DE-588)4115557-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Pharmakodynamik |0 (DE-588)4174134-1 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Pharmakokinetik |0 (DE-588)4115557-9 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Pharmakodynamik |0 (DE-588)4174134-1 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a Rowland, Malcolm |e Verfasser |4 aut | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020621333&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-020621333 | ||
Datensatz im Suchindex
| _version_ | 1804143343606693888 |
|---|---|
| adam_text | Contents
Dedication Mi
About the Authors v
Preface vii
CHAPTER 1 Opening Comments 1
SECTION I BASIC CONSIDERATIONS 13
CHAPTER 2 Input-Exposure Relationships 15
CHAPTER 3 Exposure-Response Relationships 27
SECTION II EXPOSURE AND RESPONSE AFTER A SINGLE DOSE 43
CHAPTER 4 Membranes: A Determining Factor 45
CHAPTER 5 Disposition Following Intravenous Bolus 63
CHAPTER 6 Extravascular Dose and Systemic Absorption 105
CHAPTER 7 Response Following a Single Dose 137
SECTION III THERAPEUTIC REGIMENS 155
CHAPTER 8 Therapeutic Window 157
CHAPTER 9 Constant-Rate Regimens 169
CHAPTER 10 Multiple-Dose Regimens 189
X Contents
SECTION IV INDIVIDUALIZATION 217
CHAPTER 11 Variability 219
CHAPTER 12 Initiating and Managing Therapy 249
Definitions of Symbols 267
Nonproprietary and Brand Names of Drugs in Text and Illustrations 271
APPENDIX A Assessment of AUC 275
APPENDIX B lonization and the pH Partition Hypothesis 279
APPENDIX C Amount of Drug in the Body on Accumulation to Plateau 283
APPENDIX D Answers to Study Problems 287
Index 317
|
| any_adam_object | 1 |
| author | Tozer, Thomas N. Rowland, Malcolm |
| author_facet | Tozer, Thomas N. Rowland, Malcolm |
| author_role | aut aut |
| author_sort | Tozer, Thomas N. |
| author_variant | t n t tn tnt m r mr |
| building | Verbundindex |
| bvnumber | BV036702945 |
| classification_rvk | VX 8550 |
| ctrlnum | (OCoLC)705879793 (DE-599)BVBBV036702945 |
| discipline | Chemie / Pharmazie |
| edition | [Nachdr.] |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01844nam a2200469 c 4500</leader><controlfield tag="001">BV036702945</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20131010 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">101005s2010 ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0781751497</subfield><subfield code="9">0-7817-5149-7</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780781751490</subfield><subfield code="9">978-0-7817-5149-0</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)705879793</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV036702945</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-20</subfield><subfield code="a">DE-188</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VX 8550</subfield><subfield code="0">(DE-625)147830:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Tozer, Thomas N.</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Introduction to pharmacokinetics and pharmacodynamics</subfield><subfield code="b">the quantitative basis of drug therapy</subfield><subfield code="c">Thomas N. Tozer ; Malcolm Rowland</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">[Nachdr.]</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Philadelphia</subfield><subfield code="b">Lippincott, Williams & Wilkins</subfield><subfield code="c">2010</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">X, 326 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacokinetics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drugs / Physiological effect</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dose-Response Relationship, Drug</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Drug Therapy / methods</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmaceutical Preparations / administration & dosage</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacocinétique</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Médicaments / Effets physiologiques</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmakokinetik</subfield><subfield code="0">(DE-588)4115557-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmakodynamik</subfield><subfield code="0">(DE-588)4174134-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Pharmakokinetik</subfield><subfield code="0">(DE-588)4115557-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Pharmakodynamik</subfield><subfield code="0">(DE-588)4174134-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rowland, Malcolm</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HBZ Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020621333&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-020621333</subfield></datafield></record></collection> |
| id | DE-604.BV036702945 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:46:09Z |
| institution | BVB |
| isbn | 0781751497 9780781751490 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-020621333 |
| oclc_num | 705879793 |
| open_access_boolean | |
| owner | DE-20 DE-188 |
| owner_facet | DE-20 DE-188 |
| physical | X, 326 S. Ill., graph. Darst. |
| publishDate | 2010 |
| publishDateSearch | 2010 |
| publishDateSort | 2010 |
| publisher | Lippincott, Williams & Wilkins |
| record_format | marc |
| spelling | Tozer, Thomas N. Verfasser aut Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy Thomas N. Tozer ; Malcolm Rowland [Nachdr.] Philadelphia Lippincott, Williams & Wilkins 2010 X, 326 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Pharmacokinetics Drugs / Physiological effect Dose-Response Relationship, Drug Drug Therapy / methods Pharmaceutical Preparations / administration & dosage Pharmacocinétique Médicaments / Effets physiologiques Pharmakokinetik (DE-588)4115557-9 gnd rswk-swf Pharmakodynamik (DE-588)4174134-1 gnd rswk-swf Pharmakokinetik (DE-588)4115557-9 s DE-604 Pharmakodynamik (DE-588)4174134-1 s Rowland, Malcolm Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020621333&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Tozer, Thomas N. Rowland, Malcolm Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy Pharmacokinetics Drugs / Physiological effect Dose-Response Relationship, Drug Drug Therapy / methods Pharmaceutical Preparations / administration & dosage Pharmacocinétique Médicaments / Effets physiologiques Pharmakokinetik (DE-588)4115557-9 gnd Pharmakodynamik (DE-588)4174134-1 gnd |
| subject_GND | (DE-588)4115557-9 (DE-588)4174134-1 |
| title | Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy |
| title_auth | Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy |
| title_exact_search | Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy |
| title_full | Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy Thomas N. Tozer ; Malcolm Rowland |
| title_fullStr | Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy Thomas N. Tozer ; Malcolm Rowland |
| title_full_unstemmed | Introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy Thomas N. Tozer ; Malcolm Rowland |
| title_short | Introduction to pharmacokinetics and pharmacodynamics |
| title_sort | introduction to pharmacokinetics and pharmacodynamics the quantitative basis of drug therapy |
| title_sub | the quantitative basis of drug therapy |
| topic | Pharmacokinetics Drugs / Physiological effect Dose-Response Relationship, Drug Drug Therapy / methods Pharmaceutical Preparations / administration & dosage Pharmacocinétique Médicaments / Effets physiologiques Pharmakokinetik (DE-588)4115557-9 gnd Pharmakodynamik (DE-588)4174134-1 gnd |
| topic_facet | Pharmacokinetics Drugs / Physiological effect Dose-Response Relationship, Drug Drug Therapy / methods Pharmaceutical Preparations / administration & dosage Pharmacocinétique Médicaments / Effets physiologiques Pharmakokinetik Pharmakodynamik |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020621333&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT tozerthomasn introductiontopharmacokineticsandpharmacodynamicsthequantitativebasisofdrugtherapy AT rowlandmalcolm introductiontopharmacokineticsandpharmacodynamicsthequantitativebasisofdrugtherapy |