Verfügbarkeit: New drugs and targets for asthma and COPD

New drugs and targets for asthma and COPD:

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Bibliographische Detailangaben
Weitere Verfasser:	Hansel, Trevor T. 1956- (HerausgeberIn)
Format:	Buch
Sprache:	English
Veröffentlicht:	Freiburg im Breisgau [u.a.] Karger 2010
Schriftenreihe:	Progress in Respiratory Research 39
Schlagworte:	Arzneimittelentwicklung Bronchialasthma Obstruktive Ventilationsstörung Targeted drug delivery Aufsatzsammlung
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	XIV, 310 S. graph. Darst.
ISBN:	9783805595667

Internformat

MARC


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Datensatz im Suchindex

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adam_text	Contents Corresponding authors . IX Foreword . XIII Preface . XIV Introduction New drugs and targets for asthma and COPD . 3 TrevorT. Hansel and Peter J. Barnes Bronchodilators Indacaterol: A new once-daily long-acting ßj-adrenoceptor agonist (LABA) . 27 Jutta Beier, Alexandre Trifilieff and Mark Higgins Aclidinium bromide, a novel long-acting muscarinic antagonist (LAMA) . 33 Amadeu Gavaldà and Esther Garda-Gil Dual-pharmacology bronchodilators for the treatment of COPD . 39 John R. Jacobsen, Jayashree Aiyar, Sharath Hegde, Adam Hughes and Mathai Mammen IgE- and epithelial-directed approaches IgE-directed approaches: A general strategy for the treatment of atopic diseases . 49 Franz Kricek Therapy directed against thymic stromal lymphopoietin (TSLP) . 55 Matthew J. Edwards Т -cell co-stimulator blockade ICOS and B7RP-1: Novel targets for monoclonal antibodies . 63 Gianluca Carlesso, Anthony J. Coyle and Ronald Herbst Pattern recognition receptors Toll-like receptor 2 as a therapeutic target in lung disease . 69 Jane A. Mitchell, Rosalinda Sorrentino, Neil Cartwright and Mark Paul-Clark Toll-like receptor 3 . 73 Michael Carty and Andrew Bowie Toll-like receptor 4 . 81 Ian Sabroe Toll-like receptor 7 and 8 agonists . 87 Hanna Harant Toll-like receptor 9 activation with CpG oligodeoxynucleotides for asthma therapy . 95 Joel N. Kline and Arthur M. Krieg Cytokines IL-5-directed approaches in the treatment of eosinophil-driven disease . 103 Richard Marshall and Isidore Faiferman Monoclonal antibody therapy directed against ¡nterleukin-5 receptor a: MEDI-563 . 109 Roland Kolbeck, Masamichi Koike, Kazuhiro Kawasaki, Katsumasa Iwashita, George L Spitalny, Nobuo Hanai, Peter A. Kiener, David Gossage, Nestor A. Molfino and Anthony J. Coyle IL-4- and IL-1 S-directed approaches . 115 Larry Borish, John W. Steinke, Marion Kasaian and Samuel J. Goldman Aerovant (recombinant human interleukin-4 variant) . 123 Malinda V. Longphre and RickW. Fuller An anti-interleukin-13 receptor αϊ antibody for the treatment of asthma . 127 Maria Elena Fuentes and Karim Dabbagh lnterleukin-7-directed approaches . 131 Zaiba Shamim, Klaus Müllerand Lars P. Ryder Monoclonal antibody therapy directed against interleukin-9: MEDI-528 . 137 Alison A. Humbles, Jennifer L Reed, Joseph Parker, Peter A. Kiener, Nestor A. Molfino, Roland Kolbeck and Anthony J. Coyle Targeting interleukin-17 in the lungs . 141 Stefan Ivanovand Anders Linden Chemokines Chemokine CCR3 antagonists . 153 Ash Bahl, Brian Springthorpe and Rob Riley Therapeutic potential of CCR4 antagonists . 161 David Hall, Alison Ford and Simon Hodgson Adhesion molecules Very late activation antigen-4 (VLA-4) antagonists . 169 Peter Vanderslice and Darren G. Woodside Selectin antagonists and their potential impact for the treatment of inflammatory lung diseases . 175 Ewald M. Aydt, Daniel Bock and Gerhard Wolff Mediator receptor antagonists Histamine H4 receptor antagonists . 187 Paul J. Dunford and Robin L Thurmond Antagonists of the prostaglandin D2 receptor CRTH2 . 193 Roy Pettipher and Trevor T. Hansel Enzyme inhibitors 5-Lipoxygenase inhibition . 201 Jaime L. Masferrer, Craig Wegner and Matt Graneto Utility of cytosolic phospholipase A2a (cPLAjO) inhibitors in the treatment of asthma . 207 James D. Clark and Cara M.M.Williams Antioxidants Antioxidant therapeutic strategies . 215 Paul Kirkham and Irfan Rahman Protease inhibitors Small-molecule neutrophil elastase inhibitors as therapies for respiratory disease . 225 Mary F. Fitzgerald The role of MMP-9 and MMP-12 inhibitors in inflammation . 231 S. Wong, MA Birrell, M.G. Belvisi, K. Stenvall and C.P. Bertrand сц -Antitrypsin therapy . 237 Philip J. Barr and Philip A. Pemberton Inhibitors of fibrosis and vessels Proteinase-activated receptor-1 inhibitors . 245 Rachel С Chambers Integrin-mediated transforming growth factor-ß activation . 251 Gisli Jenkins and Dean Sheppard Small-molecule inhibitors of transforming growth factor-ß type I receptor kinase (ALK5) . 255 Darren H.Wong and Linda S. Higgins Serum amyloid P: A novel antifibrotic agent with therapeutic potential . 261 Mark L Lupher, Jr. and W. Scott Willett Inhibitors of cell signaling and transcription Phosphodiesterase type 4 (PDE4) inhibition: The search for effective therapy with minimal side effects . 269 Mike Yeadon, Nick Clarke and Jon Ward Therapy directed against с -kit (CD1 17) and PDGF transmembrane receptor tyrosine kinases . 279 Christoph Walker, David Rodman and Trevor T. Hansel Syk kinase inhibitors . 283 Jane Denyer and Vipul Patel Targeting protein kinase C -θ for asthma . 289 Divya Chaudhary, Diane H. Boschelli and Marion! Kasaian Nucleic acid therapy A multitargeted antisense therapy directed at CCR3 and the common ß-chain of IL-S/IL-S/GM-CSF . 297 Luc Paquet, Paolo Renzi, Nicolay Ferrari and Mark Parry-Billings Author Index . 303 Subject Index . 304
any_adam_object	1
author2	Hansel, Trevor T. 1956-
author2_role	edt
author2_variant	t t h tt tth
author_GND	(DE-588)172588405
author_facet	Hansel, Trevor T. 1956-
building	Verbundindex
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ctrlnum	(OCoLC)680674009 (DE-599)BVBBV036670885
dewey-full	616.238061
dewey-hundreds	600 - Technology (Applied sciences)
dewey-ones	616 - Diseases
dewey-raw	616.238061
dewey-search	616.238061
dewey-sort	3616.238061
dewey-tens	610 - Medicine and health
discipline	Medizin
format	Book
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spelling	New drugs and targets for asthma and COPD ed. Trevor T. Hansel ... Freiburg im Breisgau [u.a.] Karger 2010 XIV, 310 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Progress in Respiratory Research 39 Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Bronchialasthma (DE-588)4069674-1 gnd rswk-swf Obstruktive Ventilationsstörung (DE-588)4213128-5 gnd rswk-swf Targeted drug delivery (DE-588)4302415-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Bronchialasthma (DE-588)4069674-1 s Obstruktive Ventilationsstörung (DE-588)4213128-5 s Targeted drug delivery (DE-588)4302415-4 s Arzneimittelentwicklung (DE-588)4143176-5 s DE-604 Hansel, Trevor T. 1956- (DE-588)172588405 edt Progress in Respiratory Research 39 (DE-604)BV011558798 39 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020589985&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
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title	New drugs and targets for asthma and COPD
title_auth	New drugs and targets for asthma and COPD
title_exact_search	New drugs and targets for asthma and COPD
title_full	New drugs and targets for asthma and COPD ed. Trevor T. Hansel ...
title_fullStr	New drugs and targets for asthma and COPD ed. Trevor T. Hansel ...
title_full_unstemmed	New drugs and targets for asthma and COPD ed. Trevor T. Hansel ...
title_short	New drugs and targets for asthma and COPD
title_sort	new drugs and targets for asthma and copd
topic	Arzneimittelentwicklung (DE-588)4143176-5 gnd Bronchialasthma (DE-588)4069674-1 gnd Obstruktive Ventilationsstörung (DE-588)4213128-5 gnd Targeted drug delivery (DE-588)4302415-4 gnd
topic_facet	Arzneimittelentwicklung Bronchialasthma Obstruktive Ventilationsstörung Targeted drug delivery Aufsatzsammlung
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