Innovative drug development for headache disorders:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
2008
|
| Ausgabe: | 1. publ. |
| Schriftenreihe: | Frontiers in headache research series
16 |
| Schlagworte: | |
| Online-Zugang: | Table of contents only Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XII, 227 S. Ill., graph. Darst. |
| ISBN: | 9780199552764 0199552762 |
Internformat
MARC
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| 245 | 1 | 0 | |a Innovative drug development for headache disorders |c ed. by Jes Olesen ... |
| 250 | |a 1. publ. | ||
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 2008 | |
| 300 | |a XII, 227 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Frontiers in headache research series |v 16 | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Headache |x Chemotherapy | |
| 650 | 4 | |a Analgesics | |
| 650 | 4 | |a Drug development | |
| 650 | 4 | |a Headache Disorders |x drug therapy | |
| 650 | 4 | |a Headache Disorders |x prevention & control | |
| 650 | 0 | 7 | |a Arzneimittelentwicklung |0 (DE-588)4143176-5 |2 gnd |9 rswk-swf |
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Datensatz im Suchindex
| _version_ | 1804143285186330624 |
|---|---|
| adam_text | Contents
Preface viii
Contributors ix
Session I Screening models
1 The human y-aminobutyric acid transporter GAT-2: from cloning to
high throughput screening 3
Bolette Christiansen, Trine Kvist, Anders A. Jensen, and Hans Brauner-Osborne
2 Low throughput preclinical models for headache 17
Peter}. Goadsby
3 Human models: screening models 25
Messoud Ashina
Session II Trials methodology
4 Stricter success criteria, qualitative and quantitative
end-points: acute versus prevention trials 31
Peer Tfelt-Hansen
5 Health-related quality of life and similar end-points 43
Carl G.H. Dahlof
6 Clinically relevant designs and outcome measures for
acute migraine trials 57
Michel D. Ferrari and Hille Koppen
7 Effectiveness of different steroid dosage in Tolosa-Hunt
syndrome with different phenotypes: some critical
points about the new International Headache
Society classification 59
E. Marchioni, S. Colnaghi, M. Versino, A. Pichiecchio,
E. Tavazzi, and G. Nappi
8 Discussion summary: Trials methodology 63
Jes Olesen
Session III Nitric oxide and spreading depression modulators
9 Inducible nitric oxide synthase and development of new
migraine treatments 67
Boris A. Chizh
vi CONTENTS
10 Mechanisms of cortical spreading depression as targets for
migraine therapy 73
Kevin C. Brennan and Andrew C. Charles
11 Tonabersat 85
Peter R. Blower and Paul C. Sharpe
12 Discussion summary: Nitric oxide and spreading
depression modulators 95
Nabih Ramadan
Session IV Calcitonin gene-related peptide and
5-hydroxytryptamine modulators
13 Calcitonin gene-related peptide: relevance for
migraine 99
Jes Olesen and Inger Jansen-Olesen
14 New 5-hydroxytryptamine-related drug targets 109
Pramod R. Saxena
15 Effect of two novel calcitonin gene-related
peptide-binding compounds in a closed
cranial window rat model 115
Louise Juhl, Lars Edvinsson, Jes Olesen,
and Inger Jansen-Olesen
16 Vasoactive intestinal polypeptide is unlikely
to be a target for headache and
migraine treatment 121
Jakob M0ller Hansen, Alexandra Maria Rahmann,
Jes Olesen, and Messoud Ashina
17 Discussion summary: Calcitonin gene-related
peptide and 5-hydroxytryptamine
modulators 129
Rigmor Jensen
Session V Ion channel modulators and antiepileptics
18 Migraine: from genes to pathophysiology - transgenic
mouse models of migraine 133
Am M.J.M. van den Maagdenberg
19 KATP channels and migraine 143
Inger Jansen-Olesen and Kenneth Beri Ploug
20 Antiepileptic drugs and migraine 153
Michael A. Rogawski
CONTENTS I vii
21 Discussion summary: Ion channel modulators
and antiepileptics 179
Pramod R. Saxena
Session VI Other future targets for headache therapy
22 Innovative drug development for headache
disorders: glutamate 185
Kirk W. Johnson, Eric S. Nisenbaum, Michael P. Johnson,
Donna K. Dieckman, Amy Clemens-Smith, Edward R. Siuda, Colin P. Dell,
Veronique Dehlinger, Kevin J. Hudziak, Sandra A. Filla, Paul L. Ornstein,
Nabih M. Ramadan, and David Bleaktnan
23 The modulation of TRPV1 channels by cannabinoidj
receptors 195
Beatrix Fioravanti and Todd W. Vanderah
24 Future targets for headache therapy: prostanoids 205
Christian Waeber
25 Role of anandamide in the modulation of
nitroglycerin-induced hyperalgesia:
a study in the rat 219
Cristina Tassorelli, Rosaria Greco, Armando Perrotta,
Simona Buscone, Giorgio Sandrini, and Giuseppe Nappi
Index 223
|
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| dewey-hundreds | 600 - Technology (Applied sciences) |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1. publ. |
| format | Book |
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| illustrated | Illustrated |
| indexdate | 2024-07-09T22:45:14Z |
| institution | BVB |
| isbn | 9780199552764 0199552762 |
| language | English |
| lccn | 2008021573 |
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| physical | XII, 227 S. Ill., graph. Darst. |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | Oxford Univ. Press |
| record_format | marc |
| series | Frontiers in headache research series |
| series2 | Frontiers in headache research series |
| spelling | Innovative drug development for headache disorders ed. by Jes Olesen ... 1. publ. Oxford [u.a.] Oxford Univ. Press 2008 XII, 227 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Frontiers in headache research series 16 Includes bibliographical references and index Headache Chemotherapy Analgesics Drug development Headache Disorders drug therapy Headache Disorders prevention & control Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Kopfschmerz (DE-588)4032416-3 gnd rswk-swf Kopfschmerz (DE-588)4032416-3 s Arzneimittelentwicklung (DE-588)4143176-5 s DE-604 Olesen, Jes Sonstige oth Frontiers in headache research series 16 (DE-604)BV004686708 16 http://www.loc.gov/catdir/toc/ecip0818/2008021573.html Table of contents only HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020582988&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Innovative drug development for headache disorders Frontiers in headache research series Headache Chemotherapy Analgesics Drug development Headache Disorders drug therapy Headache Disorders prevention & control Arzneimittelentwicklung (DE-588)4143176-5 gnd Kopfschmerz (DE-588)4032416-3 gnd |
| subject_GND | (DE-588)4143176-5 (DE-588)4032416-3 |
| title | Innovative drug development for headache disorders |
| title_auth | Innovative drug development for headache disorders |
| title_exact_search | Innovative drug development for headache disorders |
| title_full | Innovative drug development for headache disorders ed. by Jes Olesen ... |
| title_fullStr | Innovative drug development for headache disorders ed. by Jes Olesen ... |
| title_full_unstemmed | Innovative drug development for headache disorders ed. by Jes Olesen ... |
| title_short | Innovative drug development for headache disorders |
| title_sort | innovative drug development for headache disorders |
| topic | Headache Chemotherapy Analgesics Drug development Headache Disorders drug therapy Headache Disorders prevention & control Arzneimittelentwicklung (DE-588)4143176-5 gnd Kopfschmerz (DE-588)4032416-3 gnd |
| topic_facet | Headache Chemotherapy Analgesics Drug development Headache Disorders drug therapy Headache Disorders prevention & control Arzneimittelentwicklung Kopfschmerz |
| url | http://www.loc.gov/catdir/toc/ecip0818/2008021573.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020582988&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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