Verfügbarkeit: Tumors of the mediastinum

Tumors of the mediastinum:

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Bibliographische Detailangaben
Hauptverfasser:	Shimosato, Yukio (VerfasserIn), Mukai, Kiyoshi (VerfasserIn), Matsuno, Yoshihiro (VerfasserIn)
Format:	Buch
Sprache:	English
Veröffentlicht:	Washington, DC American Registry of Pathology [u.a.] 2010
Schriftenreihe:	AFIP atlas of tumor pathology Fourth series ; 11
Schlagworte:	Mediastinal Neoplasms / pathology / Atlases Mediastinaltumor Atlas
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	Includes bibliographical references and index
Beschreibung:	XV, 322 S. zahlr. Ill., graph. Darst. 29 cm
ISBN:	9781933477077 1933477075

Internformat

MARC


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Datensatz im Suchindex

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adam_text	[ ;■ CONTENTS 1. Anatomy and Anatomic Compartments of the Mediastinum ..................... 1 The Mediastinum ...................................................... 1 Normal Thymus Gland ................................................. 1 Embryology ........................................................ 2 Anatomic Location ................................................... 3 Gross Findings ...................................................... 4 Microscopic Findings ................................................. 4 Maturation of Thymocytes ............................................ 15 Involution ......................................................... 16 2. Thymoma .............................................................. 19 Classification of Thymic Tumors .......................................... 19 Thymoma ............................................................ 19 General Features ..................................................... 23 Clinical Features ..................................................... 24 Diagnostic Approach ................................................. 25 Gross Findings ...................................................... 29 Microscopic Findings ................................................. 33 Cellular Subtypes .................................................... 41 Histologie Subtypes .................................................. 48 Histogenetic Subtypes ................................................ 55 Controversies Surrounding Histogenetic and WHO Histologie Subtypes ......... 56 Variants and Uncommon Histologie Subtypes ............................. 58 Histologie Factors Associated with Degree of Malignancy .................... 67 Frozen Section Findings ............................................... 77 Cytologie Findings ................................................... 77 Immunohistochemistry and Functional Correlation ........................ 84 Ultrastructural Findings ............................................... 89 Molecular and Other Special Techniques ................................. 94 Differential Diagnosis ................................................. 97 Conditions and Diseases Associated with Thymoma ........................ 99 Spread and Métastases ................................................101 Staging ............................................................102 Treatment ..........................................................105 Prognosis ..........................................................105 3. Thymic Carcinoma .......................................................115 General Features .......................................................115 xi Tumors of the Mediastinum Clinical Features .......................................................116 Gross Findings ........................................................118 Microscopic Findings and Histologie Subtypes ...............................118 Squamous Cell Carcinoma .............................................120 Basaloid Carcinoma ..................................................127 Mucoepidermoid Carcinoma ...........................................127 Adenosquamous Carcinoma ...........................................129 Adenocarcinoma ....................................................131 Carcinoma with Adenoid Cystic Carcinoma-Like Features ....................135 Lymphoepithelioma-Like Carcinoma ....................................135 Clear Cell Carcinoma .................................................135 Large Cell Carcinoma (Un differentiated Carcinoma in the WHO Classification) . . 137 Sarcomatoid Carcinoma ...............................................138 Carcinoma with t(15;19) Translocation ...................................139 Cytologie Findings .....................................................139 Immunohistochemical Findings ..........................................141 Molecular and Other Special Techniques ....................................143 Prognostic and Malignancy-Associated Factors ...............................144 TNM and Stage ......................................................144 Histologie Types .....................................................144 Degree of Histologie Differentiation and Cell Atypia ........................145 Immunohistochemical Prognostic Factors ................................146 Nuclear DNA Content and Histograms ...................................146 Differential Diagnosis ...................................................146 Tumor Spread and Metastasis .............................................149 Treatment ............................................................149 Prognosis ............................................................150 Association of Epstein-Barr Virus with Development of Thymic Epithelial Tumors . . 150 4. Thymic Neuroendocrine Carcinomas ........................................157 Well-Differentiated Neuroendocrine Carcinoma (Carcinoid Tumor) ..............157 Histogenesis ........................................................158 Clinical Findings ....................................................159 Gross Findings ......................................................160 Microscopic Findings ................................................. 160 Histologie Variants ...................................................166 Ultrastructural Findings ...............................................168 Cytologie Findings ...................................................168 Immunohistochemical Findings (Including Functional Correlation with Paraneoplastic Syndrome) .........................................168 xn Contents Molecular and Other Special Diagnostic Techniques ........................ 176 Differential Diagnosis ................................................. 176 Treatment and Prognosis .............................................. 177 Poorly Differentiated Neuroendocrine Carcinomas ........................... 178 Large Cell Neuroendocrine Carcinoma ................................... 178 Small Cell Carcinoma of Neuroendocrine Type ............................ 179 Histogenesis ........................................................ 184 Cytologie Findings ................................................... 184 Immunohistochemical Findings ........................................ 184 Molecular and Other Special Diagnostic Techniques ........................ 185 Differential Diagnosis ................................................. 185 Prognosis and Malignancy-Associated Factors ............................. 185 Treatment .......................................................... 185 Combined Thymic Epithelial Tumors (Including Neuroendocrine Carcinomas) ..... 185 5. Germ Cell Tumors ....................................................... 193 Definition and Classification ............................................. 193 Incidence and Clinical Features ........................................... 193 Diagnostic Approach ................................................... 196 Tumors of One Histologie Type ........................................... 201 Teratoma ........................................................... 201 Seminoma (Germinoma) .............................................. 208 Embryonal Carcinoma ................................................ 211 Yolk Sac Tumor (Endodermal Sinus Tumor) ............................... 211 Choriocarcinoma .................................................... 212 Tumors of More Than One Histologie Type: Mixed Germ Cell Tumors ............ 212 Teratoma with Nongerminal Malignant Tumor ............................ 212 Molecular and Other Special Techniques .................................... 216 Malignant Germ Cell Tumors of Infants and Young Children ................. 216 Malignant Germ Cell Tumors of Adolescents and Adults ..................... 216 Pure Teratoma (Immature and Mature) ................................... 216 Tumor Spread and Staging ............................................... 216 Treatment and Prognosis ................................................ 216 6. Malignant Lymphomas and Hematopoietic Neoplasms .......................... 225 B-Cell Lymphomas ..................................................... 225 Primary Mediastinal Large B-Cell Lymphoma .............................. 225 Thymic Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue .................................................. 231 Т -Cell Lymphomas ..................................................... 237 xiii Tumors of the Mediastinum Precursor T-Lymphoblastic Leukemia/Lymphoblastic Lymphoma (Precursor T-Cell Acute Lymphoblastic Leukemia/Precursor Т -Cell Lymphoblastic Lymphoma) . . 237 Anaplastic Large Cell Lymphoma and Other Rare Mature T- and NK-Cell Lymphomas of the Mediastinum .....................................241 Hodgkin Lymphoma ...................................................241 Histocytic and Dendritic Cell Tumors ......................................245 Langerhans Cell Histiocytosis and Sarcoma ...............................246 Histiocytic Sarcoma ..................................................246 Follicular Dendritic Cell Tumor/Sarcoma .................................246 Interdigitating Dendritic Cell Tumor/Sarcoma .............................246 Myeloid Sarcoma and Extramedullary Acute Myeloid Leukemia .................247 7. Secondary Involvement of the Thymus by Carcinoma and Mesothelioma ...........253 Secondary Carcinoma Involving the Thymus ................................253 Distinction between Thymic and Pulmonary Carcinomas ....................254 Mesothelioma Involving the Thymus ......................................255 8. Other Tumors and Tumor-Like Lesions of the Thymus ...........................257 Thymolipoma ......................................................... 257 Ectopie Hamartomatous Thymoma ........................................ 260 Malignant Melanoma ................................................... 262 Thymic Cyst .......................................................... 262 Congenital Thymic Cyst .............................................. 262 Acquired Multilocular Thymic Cyst ..................................... 263 Other Tumor-Like Lesions ............................................... 265 9. Non-Neoplastic Conditions of the Thymus .................................... 271 Thymus in Immunodeficiency ............................................271 Thymus in Primary Immunodeficiencies .................................272 Thymus in Secondary Immunodeficiencies ................................274 Thymic Hyperplasia ....................................................274 True Thymic Hyperplasia ..............................................274 Lymphoid Hyperplasia ................................................276 10. Ectopie Tissue and Tumors in the Anterosuperior Mediastinum ....................281 Thyroid Lesions .......................................................281 Parathyroid Lesions ....................................................281 11. Mesenchymal and Neurogenic Tumors of the Mediastinum Excluding the Heart and Great Vessels ....................................................285 Mesenchymal Tumors ..................................................285 Benign Mesenchymal Tumors and Tumor-Like Lesions ......................285 Mesenchymal Tumors of Intermediate Malignancy .........................288 Malignant Mesenchymal Tumors .......................................292 xiv Contents Neurogenic Tumors and Tumors of Paraganglia .............................. 295 Immunohistochemistry of Neurogenic Tumors and Paraganglioma............ 301 12. Mediastinal Cysts (Other Than Thymic Cyst) .................................. 305 Bronchogenic Cyst ..................................................... 305 Esophageal Cyst ....................................................... 307 Gastroenteric Cyst ..................................................... 307 Celomic Cyst (Pericardial Cyst and Mesothelial Cyst) ......................... 307 Thoracic Duct Cyst ..................................................... 308 Cyst-Like Lesions Other Than True Cysts ................................... 308 13. Other Mediastinal Tumor-Like Conditions .................................... 309 Castleman Disease ..................................................... 309 Hyaline-Vascular Type Castleman Disease ................................. 310 Plasma Cell Type Castleman Disease ..................................... 311 Index ................................................................. 315 xv
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author	Shimosato, Yukio Mukai, Kiyoshi Matsuno, Yoshihiro
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discipline	Medizin
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series	AFIP atlas of tumor pathology
series2	AFIP atlas of tumor pathology : Fourth series
spelling	Shimosato, Yukio Verfasser (DE-588)142482943 aut Tumors of the mediastinum by Yukio Shimosato ; Kiyoshi Mukai ; Yoshihiro Matsuno Washington, DC American Registry of Pathology [u.a.] 2010 XV, 322 S. zahlr. Ill., graph. Darst. 29 cm txt rdacontent n rdamedia nc rdacarrier AFIP atlas of tumor pathology : Fourth series 11 Includes bibliographical references and index Mediastinal Neoplasms / pathology / Atlases Mediastinaltumor (DE-588)4123730-4 gnd rswk-swf 1\p (DE-588)4143303-8 Atlas gnd-content Mediastinaltumor (DE-588)4123730-4 s DE-604 Mukai, Kiyoshi Verfasser (DE-588)14248301X aut Matsuno, Yoshihiro Verfasser (DE-588)142407194 aut AFIP atlas of tumor pathology Fourth series ; 11 (DE-604)BV019661402 11 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020516393&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk
spellingShingle	Shimosato, Yukio Mukai, Kiyoshi Matsuno, Yoshihiro Tumors of the mediastinum AFIP atlas of tumor pathology Mediastinal Neoplasms / pathology / Atlases Mediastinaltumor (DE-588)4123730-4 gnd
subject_GND	(DE-588)4123730-4 (DE-588)4143303-8
title	Tumors of the mediastinum
title_auth	Tumors of the mediastinum
title_exact_search	Tumors of the mediastinum
title_full	Tumors of the mediastinum by Yukio Shimosato ; Kiyoshi Mukai ; Yoshihiro Matsuno
title_fullStr	Tumors of the mediastinum by Yukio Shimosato ; Kiyoshi Mukai ; Yoshihiro Matsuno
title_full_unstemmed	Tumors of the mediastinum by Yukio Shimosato ; Kiyoshi Mukai ; Yoshihiro Matsuno
title_short	Tumors of the mediastinum
title_sort	tumors of the mediastinum
topic	Mediastinal Neoplasms / pathology / Atlases Mediastinaltumor (DE-588)4123730-4 gnd
topic_facet	Mediastinal Neoplasms / pathology / Atlases Mediastinaltumor Atlas
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020516393&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
volume_link	(DE-604)BV019661402
work_keys_str_mv	AT shimosatoyukio tumorsofthemediastinum AT mukaikiyoshi tumorsofthemediastinum AT matsunoyoshihiro tumorsofthemediastinum

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