Drug design of zinc-enzyme inhibitors: functional, structural, and disease applications
Gespeichert in:
Weitere Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Hoboken, NJ
Wiley
2009
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Schriftenreihe: | Wiley series in drug discovery and development
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Formerly CIP Uk. - Includes bibliographical references and index |
Beschreibung: | XV, 1022 S., [16] Bl. Ill., graph. Darst. 24 cm |
ISBN: | 9780470275009 0470275006 |
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DRUG DESIGN OF ZINC-ENZYME INHIBITORS FUNCTIONAL, STRUCTURAL, AND
DISEASE APPLICATIONS EDITED BY CLAUDIU T. SUPURAN JEAN-YVES WINUM WILEY
A JOHN WILEY & SONS, INC., PUBLICATION CONTENTS PREFACE IX CONTRIBUTORS
XI PARTI INTRODUCTION 1 1. INTRODUCTION TO ZINC ENZYMES AS DRUG TARGETS
3 CLAUDIA T. SUPURAN AND JEAN- YVES WINUM PART II DRUG DESIGN OF
CARBONIC ANHYDRASE INHIBITORS AND ACTIVATORS 13 2. CARBONIC ANHYDRASES
AS DRUG TARGETS: GENERAL PRESENTATION 15 CLAUDIA T. SUPURAN 3. ZINC
BINDING FUNCTIONS IN THE DESIGN OF CARBONIC ANHYDRASE INHIBITORS 39
JEAN-YVES WINUM, JEAN-LOUIS MONTERO, ANDREA SCOZZAFAVA, AND CLAUDIU T.
SUPURAN 4. X-RAY CRYSTALLOGRAPHY OF CARBONIC ANHYDRASE INHIBITORS AND
ITS IMPORTANCE IN DRUG DESIGN 73 VINCENZO ALTERIO, ANNA DI FIORE, KATIA
D'AMBROSIO, CLAUDIU T. SUPURAN, AND GIUSEPPINA DE SIMONE 5. ANTIGLAUCOMA
CARBONIC ANHYDRASE INHIBITORS AS OPHTHALOMOLOGIC DRUGS 139 FRANCESCO
MINCIONE, ANDREA SCOZZAFAVA, AND CLAUDIU T. SUPURAN 6. DIURETICS WITH
CARBONIC ANHYDRASE INHIBITORY ACTIVITY: TOWARD NOVEL APPLICATIONS FOR
SULFONAMIDE DRUGS 155 DANIELA VULLO, ALESSIO INNOCENTI, AND CLAUDIU T.
SUPURAN 7. DRUG DESIGN OF CARBONIC ANHYDRASE INHIBITORS AS
ANTICONVULSANT AGENTS 171 ANNE THIRY, JEAN-MICHEL DOGNE, CLAUDIU T.
SUPURAN, AND BERNARD MASEREEL VI CONTENTS 8. CARBONIC ANHYDRASE
INHIBITORS TARGETING CANCER: THERAPEUTIC, IMMUNOLOGIE, AND DIAGNOSTIC
TOOLS TARGETING ISOFORMS IX AND XII 193 SILVIA PASTOREKOVA, MONIKA
BARATHOVA, JURAJ KOPACEK, AND JAROMIR PASTOREK 9. FLUORESCENT- AND
SPIN-LABELED SULFONAMIDES AS PROBE FOR CARBONIC ANHYDRASE IX 223
ALESSANDRO CECCHI, LAURA CIANI, SANDRA RISTORI, AND CLAUDIU T. SUPURAN
10. DRUG DESIGN OF ANTIOBESITY CARBONIC ANHYDRASE INHIBITORS 241
GIUSEPPINA DE SIMONE AND CLAUDIU T. SUPURAN 11. DUAL CARBONIC ANHYDRASE
AND CYCLOOXYGENASE-2 INHIBITION 255 JEAN-MICHEL DOGNE, ANNE THIRY,
BERNARD MASEREEL, AND CLAUDIU T. SUPURAN 12. ADVANCES IN THE INHIBITORY
AND STRUCTURAL INVESTIGATIONS ON CARBONIC ANHYDRASE ISOZYMES XIII AND XV
273 MIKA HILVO, GIUSEPPINA DE SIMONE, CLAUDIU T. SUPURAN, AND SEPPO
PARKKILA 13. MECHANISM AND INHIBITION OF THE SS-CLASS AND Y-CLASS
CARBONIC ANHYDRASES 285 JAMES G. FERRY AND CLAUDIU T. SUPURAN 14. FUNGAL
AND NEMATODE CARBONIC ANHYDRASES: THEIR INHIBITION IN DRUG DESIGN 301
REBECCA A. HALL AND FRITZ. A. MUEHLSCHLEGEL 15. CRYSTALLOGRAPHIC STUDIES
ON CARBONIC ANHYDRASES FROM FUNGAL PATHOGENS FOR STRUCTURE-ASSISTED DRUG
DEVELOPMENT 323 UTA-MARIA OHNDORF, CHRISTINE SCHLICKER, AND CLEMENS
STEEGBORN 16. MALARIA PARASITE CARBONIC ANHYDRASE AND ITS INHIBITION IN
THE DEVELOPMENT OF NOVEL THERAPIES OF MALARIA 335 JERAPAN KRUNGKRAI,
SUDARATANA R. KRUNGKRAI, AND CLAUDIU T. SUPURAN 17. INHIBITORS OF
HELICOBACTER PYLORI A- AND SS-CARBONIC ANHYDRASES AS NOVEL DRUGS FOR
GASTRODUODENAL DISEASES 359 ISAO NISHIMORI, HIROAKI TAKEUCHI, AND
CLAUDIU T. SUPURAN 18. QSAR OF CARBONIC ANHYDRASE INHIBITORS AND THEIR
IMPACT ON DRUG DESIGN 375 ADRIANO MARTINELLI AND TIZIANO TUCCINARDI 19.
SELECTIVITY ISSUES IN THE DESIGN OF CA INHIBITORS 399 CLAUDIU T. SUPURAN
AND JEAN- YVES WINUM CONTENTS VUE 20. BICARBONATE TRANSPORT METABOLONS
415 DANIELLE E. JOHNSON AND JOSEPH R. CASEY 21. METAL COMPLEXES OF
SULFONAMIDES AS DUAL CARBONIC ANHYDRASE INHIBITORS 439 MARC A. ILIES 22.
DRUG DESIGN STUDIES OF CARBONIC ANHYDRASE ACTIVATORS 473 CLAUDIA
TEMPERINI, ANDREA SCOZZAFAVA, AND CLAUDIU T. SUPURAN PART III DRUG
DESIGN OF MATRIX METALLOPROTEINASE INHIBITORS 487 23. MATRIX
METALLOPROTEINASES: AN OVERVIEW 489 HIDEAKI NAGASE AND ROBERT VISSE 24.
MMP INHIBITORS BASED ON EARLIER SUCCINIMIDE STRATEGIES: FROM EARLY TO
NEW APPROACHES 519 M. AMELIA SANTOS 25. DRUG DESIGN OF SULFONYLATED MMP
INHIBITORS 549 ARMANDO ROSSELLO AND ELISA NUTI 26. ADAMS AND ADAMTS
SELECTIVE SYNTHETIC INHIBITORS 591 ARMANDO ROSSELLO, ELISA NUTI, AND
ALFONSO MARESCA 27. QSAR STUDIES OF MMP INHIBITORS 647 TIZIANO
TUCCINARDI AND ADRIANO MARTINELLI PART IV DRUG DESIGN OF BACTERIAL ZINC
PROTEASE INHIBITORS 673 28. BACTERIAL ZINC PROTEASES AS ORPHAN TARGETS
675 CLAUDIU T. SUPURAN 29. BOTULINUS TOXIN, TETANUS TOXIN, AND ANTHRAX
LETHAL FACTOR INHIBITORS 705 ANTONIO MASTROLORENZO AND CLAUDIU T.
SUPURAN 30. CLOSTRIDIUM HISTOLYTICUM COLLAGENASE INHIBITORS IN THE DRUG
DESIGN 721 CLAUDIU T. SUPURAN 31. OTHER BACTERIAL ZINC PEPTIDASES AS
POTENTIAL DRUG TARGETS 731 KUNIHIKO WATANABE VUEI CONTENTS PART V DRUG
DESIGN STUDIES OF OTHER ZINC-CONTAINING ENZYMES 749 32. ANGIOTENSIN
CONVERTING ENZYME (ACE) INHIBITORS 751 ANA CAEMARA-ARTIGAS, VICENTE
JARA-PEREZ, AND MONTSERRAT ANDUEJAR-SAENCHEZ 33. P-III METALLOPROTEINASE
(LEUCUROLYSIN-B) FROM BOTHROPS LEUCURUS VENOM: ISOLATION AND POSSIBLE
INHIBITION 789 ELADIO F. SANCHEZ AND JOHANNES A. EBLE 34. CAAX-PROTEIN
PRENYLTRANSFERASE INHIBITORS 813 MARTIN SCHLITZER, REGINA ORTMANN, AND
MIRKO ALTENKAEMPER 35. HISTONE DEACETYLASE INHIBITORS 859 PAUL W. FINN
36. RECENT DEVELOPMENT OF DIAGNOSTIC AND THERAPEUTIC AGENTS TARGETING
GLUTAMATE CARBOXYPEPTIDASE II (GCPII) 881 YOUNGJOO BYUN, RONNIE C.
MEASE, SHAWN E. LUPOLD, AND MARTIN G. POMPER 37. TARGETING HIV-1
INTEGRASE ZINC BINDING MOTIF 911 MARIO SECHI, MAURO CARCELLI, DOMINGA
ROGOLINO, AND NOURI NEAMATI 38. INHIBITORS OF HISTIDINOL DEHYDROGENASES
AS ANTIBACTERIAL AGENTS 937 PASCALE JOSEPH, FRANCOIS TURTAUT, STEPHAN
KOEHLER, AND JEAN-YVES WINUM 39. DIHYDROOROTASE INHIBITORS 951 MIHWA LEE,
MEGAN J. MAEHER, RICHARD I. CHRISTOPHERSON, AND J. MITCHELL GUSS 40.
APOBEC3G: A PROMISING ANTIVIRAL TARGET 981 CLAUDIU T. SUPURAN AND
JEAN-YVES WINUM INDEX 989 |
any_adam_object | 1 |
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ctrlnum | (OCoLC)608562554 (DE-599)BSZ312803818 |
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id | DE-604.BV036497913 |
illustrated | Illustrated |
indexdate | 2024-10-18T14:00:45Z |
institution | BVB |
isbn | 9780470275009 0470275006 |
language | English |
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owner_facet | DE-19 DE-BY-UBM |
physical | XV, 1022 S., [16] Bl. Ill., graph. Darst. 24 cm |
publishDate | 2009 |
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publisher | Wiley |
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series2 | Wiley series in drug discovery and development |
spelling | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications ed. by Claudiu T. Supuran ... Hoboken, NJ Wiley 2009 XV, 1022 S., [16] Bl. Ill., graph. Darst. 24 cm txt rdacontent n rdamedia nc rdacarrier Wiley series in drug discovery and development Formerly CIP Uk. - Includes bibliographical references and index Zinc enzymes / Inhibitors / Therapeutic use Drugs / Design Supuran, Claudiu T. 1962- (DE-588)139760229 edt GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020420392&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications |
title | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications |
title_auth | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications |
title_exact_search | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications |
title_full | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications ed. by Claudiu T. Supuran ... |
title_fullStr | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications ed. by Claudiu T. Supuran ... |
title_full_unstemmed | Drug design of zinc-enzyme inhibitors functional, structural, and disease applications ed. by Claudiu T. Supuran ... |
title_short | Drug design of zinc-enzyme inhibitors |
title_sort | drug design of zinc enzyme inhibitors functional structural and disease applications |
title_sub | functional, structural, and disease applications |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020420392&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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