Handbook of non-invasive drug delivery systems: non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier/William Andrew
2010
|
| Ausgabe: | 1. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XXIII, 301 S. Ill., graph. Darst. |
| ISBN: | 9780815520252 0815520255 |
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Datensatz im Suchindex
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| adam_text | HANDBOOK OF NON-INVASIVE DRUG DELIVERY SYSTEMS NON-INVASIVE AND
MINIMALLY- INVASIVE DRUG DELIVERY SYSTEMS FOR PHARMACEUTICAL AND
PERSONAL CARE PRODUCTS EDITED BY DR VITTHAL S. KULKARNI AMSTERDAM *
BOSTON * HEIDELBERG . LONDON NEW YORK . OXFORD * PARIS SAN DIEGO * SAN
FRANCISCO * SINGAPORE * SYDNEY * TOKYO ELSEVIER WILLIAM ANDREW IS AN
IMPRINT OF ELSEVIER PREFACE XI EDITOR BIOGRAPHY XIII CONTRIBUTORS XV
ACKNOWLEDGEMENT XXIII CHAPTER 1 TOPICAL AND TRANSDERMAL DRUG DELIVERY 1
H.N. SHIVAKUMAR AND S. NARASIMHA MURTHY 1.1 STRUCTURE OF THE SKIN 1
1.1.1 DERMIS AND HYPODERMIS 3 1.2 TOPICAL VS. TRANSDERMAL DRUG DELIVERY
3 1.2.1 TOPICAL DRUG DELIVERY 3 1.2.2 TRANSDERMAL PATCH SYSTEMS 4 1.3
PERCUTANEOUS ABSORPTION PATHWAYS 5 1.4 APPROACHES TO ENHANCE PASSIVE
CUTANEOUS DRUG ABSORPTION 6 1.4.1 SUPERSATURATION OF DRUG 6 1.4.2
EUTECTIC SYSTEMS 7 1.4.3 PRODRUG APPROACH 7 1.4.4 ION PAIR FORMATION 8
1.4.5 COMPLEXATION 8 1.4.6 LIPOSOMES 9 1.4.7 MICROEMULSIONS 13 1.4.8
ORGANOGELS 14 1.4.9 SOLID LIPID NANOPARTICLES 15 1.4.10 LIQUID
CRYSTALLINE SYSTEMS 16 1.4.11 CHEMICAL PERMEATION ENHANCERS 16 1.5
CONCLUSIONS 26 REFERENCES 27 CHAPTER 2 MICELLAR NANOPARTICLES:
APPLICATIONS FOR TOPICAL AND PASSIVE TRANSDERMAL DRUG DELIVERY 37 ROBERT
W. LEE, DINESH B. SHENOY AND RAJIV SHEEL 2.1 INTRODUCTION 37 2.1.1 MNP
COMPOSITION AND STRUCTURES 39 2.1.2 PHYSICOCHEMICAL CHARACTERIZATION 42
2.1.3 ANTIMICROBIAL PROPERTIES 44 2.2 TRANSDERMAL DRUG DELIVERY
APPLICATIONS OF MNP TECHNOLOGY 45 2.2.1 ESTRASORB* - COMMERCIAL
VALIDATION OF MNP TECHNOLOGY 45 2.2.2 RALOXIFENE MNP PRODUCT 47 2.2.3
NICOTINE MNP PRODUCT 51 2.3 TOPICAL DRUG DELIVERY APPLICATIONS OF MNP
TECHNOLOGY 53 2.4 CONCLUSION 54 REFERENCES 56 FURTHER READING 58 CHAPTER
3 EMULSIONS AND MICROEMULSIONS FOR TOPICAL AND TRANSDERMAL DRUG DELIVERY
59 GUANG WEI LU AND PING GAO 3.1 OVERVIEW OF BASIC ASPECTS OF EMULSIONS
AND MICROEMULSIONS 59 3.1.1 INTRODUCTION 59 3.1.2 METHODS OF
CHARACTERIZATION 63 3.1.3 STABILITY EVALUATION 69 3.2 APPLICATION OF
EMULSIONS FOR TOPICAL AND TRANSDERMAL DRUG DELIVERY 71 3.2.1 DRUG
TRANSPORT FROM AN EMULSION TO THE SKIN 71 3.2.2 INVESTIGATION OF TOPICAL
AND TRANSDERMAL DELIVERY IN HUMAN SUBJECTS 78 3.2.3 FORMULATION
STRATEGIES FOR EMULSION-BASED PRODUCTS 80 3.3 ADVANCES IN USING
MICROEMULSIONS AS TOPICAL AND TRANSDERMAL DRUG DELIVERY SYSTEMS 86
REFERENCES 91 CHAPTER 4 LONTOPHORETIC TRANSDERMAL DRUG DELIVERY 95
LONGSHENG HU, PRIYA BATHEJA, VICTOR MEIDAN AND BOZENA B. MICHNIAK-KOHN
4.1 INTRODUCTION 95 4.2 HISTORY AND DEVELOPMENT OF IONTOPHORESIS 97 4.3
ADVANTAGES AND LIMITATIONS OF IONTOPHORESIS 97 4.4 LONTOPHORETIC
DELIVERY PRINCIPLES AND SYSTEM COMPONENTS 98 4.5 DRUG TRANSPORT IN
IONTOPHORESIS 100 4.6 PATHWAYS FOR IONTOPHORETIC TRANSPORT AND FACTORS
AFFECTING THE SAME 102 4.7 PROPERTIES OF THE DRUG/ION: CONCENTRATION,
COMPETING IONS, AND MOLECULAR SIZE 103 4.8 PROPERTIES OF THE
IONTOPHORETIC SYSTEM: PH, CURRENT 103 4.9 COMBINATION STRATEGIES TO
IMPROVE TRANSDERMAL IONTOPHORETIC DRUG DELIVERY 105 4.9.1 IONTOPHORESIS
WITH ELECTROPORATION 106 4.9.2 IONTOPHORESIS WITH CHEMICAL ENHANCERS 106
4.9.3 IONTOPHORESIS WITH MICRONEEDLES 107 4.9.4 IONTOPHORESIS WITH
SONOPHORESIS 108 4.9.5 ION-EXCHANGE MATERIALS 109 4.9.6 OTHER
COMBINATIONS 110 4.10 REVERSE IONTOPHORESIS 110 4.11 APPLICATIONS OF
IONTOPHORESIS 111 4.12 CURRENT AND FUTURE DEVELOPMENT 113 REFERENCES 114
CHAPTER 5 ULTRASOUND-BASED TECHNOLOGY FOR SKIN BARRIER PERMEABILIZATION
119 VICTOR MEIDAN AND BOZENA B. MICHNIAK-KOHN 5.1 INTRODUCTION 119 5.2
WHAT IS ULTRASOUND? 120 5.3 ULTRASOUND BIOEFFECTS 121 5.3.1 CAVITATION
121 5.3.2 HEATING 122 5.3.3 MICROSTREAMING 122 5.4 HISTORICAL BACKGROUND
122 5.5 SONOPHORESIS FOR ENHANCED DRUG DELIVERY 123 5.5.1 MECHANISMS 125
5.6 ONGOING DEVELOPMENTS 127 5.6.1 EFFECTIVE DELIVERY OF MACROMOLECULES
127 5.6.2 REVERSE SONOPHORESIS FOR TRANSDERMAL DIAGNOSTICS 128 5.6.3
ADVANCES IN TRANSDUCER FABRICATION 129 5.7 CURRENT CHALLENGES AND TRENDS
130 REFERENCES 131 CHAPTER 6 MICRONEEDLES - MINIMALLY INVASIVE
TRANSDERMAL DELIVERY TECHNOLOGY 135 DIKSHA KAUSHIK, BRIAN KILFOYLE,
RASHMI THAKUR AND BOZENA B. MICHNIAK-KOHN 6.1 INTRODUCTION 135 6.2
MICRONEEDLE GEOMETRY 136 6.2.1 SOLID MICRONEEDLES 137 6.2.2 HOLLOW
MICRONEEDLES 139 6.2.3 BIODEGRADABLE MICRONEEDLES 140 6.3 TYPES OF
APPROACH 140 6.3.1 POKE WITH PATCH TECHNIQUE 142 6.3.2 COAT AND POKE
TECHNIQUE 142 6.3.3 DIP AND SCRAPE TECHNIQUE 142 6.4 FACTORS INFLUENCING
TRANSDERMAL PERMEATION 143 6.4.1 DEPTH OF PERMEATION 143 6.4.2 COATING
STRATEGIES 143 6.4.3 MICRONEEDLE GEOMETRY AND FORCE OF PENETRATION 148
6.5 MICRONEEDLE TECHNOLOGY IN DRUG DELIVERY 151 6.6 COMMERCIALIZATION OF
MICRONEEDLE TECHNOLOGY 157 6.7 CONCLUSION 160 REFERENCES 161 7.1 7.2 7.3
7.4 7.5 INTRODUCTION THE ANATOMY OF THE EYE DELIVERY SYSTEMS FOR THE
ANTERIOR SEGMENT 7.3.1 7.3.2 7.3.3 7.3.4 7.3.5 7.3.6 7.3.7 VISCOUS
SOLUTIONS GELS BIOADHESIVE POLYMERS NANOSUSPENSIONS INSERTS LIPOSOMES
OTHERS RETINAL DRUG DELIVERY SYSTEMS 7.4.1 7.4.2 7.4.3 7.4.4 7.4.5
NON-ERODIBLE IMPLANTS ERODIBLE IMPLANTS BOLUS INJECTIONS PERIOCULAR DRUG
DELIVERY OTHERS CONCLUSIONS REFERENCES CHAPTER 7 RECENT ADVANCES IN
OPHTHALMIC DRUG DELIVERY 165 JAMES N. CHANG 165 167 169 170 171 173 175
176 177 178 179 180 181 182 182 186 186 186 CHAPTER 8 NASAL DELIVERY OF
MICRO- AND NANO-ENCAPSULATED DRUGS 193 JOE MCDONOUGH, HONG DIXON AND
MICHAEL LADIKA 8.1 INTRODUCTION 193 8.2 PHYSIOLOGY OF THE NOSE 198 8.3
DRUG DELIVERY FORMULATION 199 8.4 MICRO- AND NANO-ENCAPSULATION 201
8.4.1 PLGA 201 8.4.2 CHITOSAN 203 8.4.3 OTHER POLYMERS 205 8.5 SUMMARY
206 REFERENCES 206 CHAPTER 9 PULMONARY DRUG DELIVERY 209 MOHAMMED ALI
9.1 GENERAL INTRODUCTION 209 9.1.1 NON-INVASIVE DRUG DELIVERY 209 9.1.2
THE HUMAN RESPIRATORY SYSTEM 211 9.1.3 PHYSICAL PROPERTIES OF DRUG
AEROSOL PARTICLES 212 9.2 PULMONARY DRUG DEPOSITION MECHANISMS 214 9.3
PULMONARY DRUG DELIVERY METHODS 218 9.3.1 METERED-DOSE INHALERS 219
9.3.2 DRY POWDER INHALERS 225 9.3.3 NEBULIZERS 227 9.3.4 COMPARABLE AND
CONTRASTING FEATURES OF MDIS, DPIS, AND NEBULIZERS 9.4 ANALYTICAL
METHODS 9.4.1 NON-INVASIVE SCINTIGRAPHIC TECHNIQUES 9.4.2 INERTIAL
IMPACTION 9.4.3 OPTICAL MICROSCOPY 9.4.4 LASER-INDUCED TOOLS 9.5
CHALLENGES AND ADVANTAGES 9.6 CONCLUSIONS REFERENCES 229 231 232 233 237
237 239 241 242 CHAPTER 10 REGULATORY ASPECTS OF NASAL AND PULMONARY
SPRAY DRUG PRODUCTS 247 DINO J. FARINA 10.1 INTRODUCTION 247 10.2
SETTING SPECIFICATIONS AND PERFORMING PRODUCT CHARACTERIZATION STUDIES
253 10.2.1 TESTS RELATED TO PRODUCT LABELING 253 10.2.2 TESTS RELATED TO
PATIENT USE/MISUSE 259 10.2.3 TESTS RELATED TO GENERAL PROPERTIES 267
10.3 CONCLUSION 287 REFERENCES 287 INDEX 291
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| indexdate | 2024-07-09T22:41:37Z |
| institution | BVB |
| isbn | 9780815520252 0815520255 |
| language | English |
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| physical | XXIII, 301 S. Ill., graph. Darst. |
| publishDate | 2010 |
| publishDateSearch | 2010 |
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| publisher | Elsevier/William Andrew |
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| spelling | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products ed. by Vitthal S. Kulkarni 1. ed. Amsterdam [u.a.] Elsevier/William Andrew 2010 XXIII, 301 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Therapeutisches System (DE-588)4267580-7 gnd rswk-swf Therapeutisches System (DE-588)4267580-7 s DE-604 Kulkarni, Vitthal S. Sonstige oth DE-601 pdf/application http://www.gbv.de/dms/bs/toc/606512802.pdf kostenfrei Inhaltsverzeichnis GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020417132&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products Therapeutisches System (DE-588)4267580-7 gnd |
| subject_GND | (DE-588)4267580-7 |
| title | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products |
| title_auth | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products |
| title_exact_search | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products |
| title_full | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products ed. by Vitthal S. Kulkarni |
| title_fullStr | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products ed. by Vitthal S. Kulkarni |
| title_full_unstemmed | Handbook of non-invasive drug delivery systems non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products ed. by Vitthal S. Kulkarni |
| title_short | Handbook of non-invasive drug delivery systems |
| title_sort | handbook of non invasive drug delivery systems non invasive and minimally invasive drug delivery systems for pharmaceutical and personal care products |
| title_sub | non-invasive and minimally-invasive drug delivery systems for pharmaceutical and personal care products |
| topic | Therapeutisches System (DE-588)4267580-7 gnd |
| topic_facet | Therapeutisches System |
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