Developmental biology:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Sunderland, MA
Sinauer
2010
|
| Ausgabe: | 9. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | Getr. Zählung Ill., graph. Darst. |
| ISBN: | 9780878933846 |
Internformat
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| 250 | |a 9. ed. | ||
| 264 | 1 | |a Sunderland, MA |b Sinauer |c 2010 | |
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| 650 | 4 | |a Developmental biology | |
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Datensatz im Suchindex
| _version_ | 1804142961739431937 |
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| adam_text | DEVELOPMENTAL BIOLOGY NINTH EDITION SCOTT F. GILBERT SWARTHMORE COLLEGE
AND THE UNIVERSITY OF HELSINKI SINAUER ASSOCIATES, INC. * PUBLISHERS *
SUNDERLAND, MASSACHUSETTS USA BRIEF CONTENTS PART I QUESTIONS
INTRODUCING DEVELOPMENTAL BIOLOGY 1 CHAPTER 1 DEVELOPMENTAL ANATOMY 5
CHAPTER 2 DEVELOPMENTAL GENETICS 31 CHAPTER 3 CELL-CELL COMMUNICATION IN
DEVELOPMENT 69 PART II SPECIFICATION INTRODUCING CELL COMMITMENT AND
EARLY EMBRYONIC DEVELOPMENT 109 CHAPTER 4 FERTILIZATION 121 CHAPTER 5
EARLY DEVELOPMENT IN SELECTED INVERTEBRATES 159 CHAPTER 6 THE GENETICS
OF AXIS SPECIFICATION IN DROSOPHILA 203 CHAPTER 7 AMPHIBIANS AND FISH
241 CHAPTER 8 BIRDS AND MAMMALS 287 PART III THE STEM CELL CONCEPT
INTRODUCING ORGANOGENESIS 323 CHAPTER 9 THE EMERGENCE OF THE ECTODERM
333 CHAPTER 10 NEURAL CREST CELLS AND AXONAL SPECIFICITY 373 CHAPTER 11
PARAXIAL AND INTERMEDIATE MESODERM 413 CHAPTER 12 LATERAL PLATE MESODERM
AND THE ENDODERM 445 CHAPTER 13 DEVELOPMENT OF THE TETRAPOD LIMB 485
CHAPTER 14 SEX DETERMINATION 511 CHAPTER 15 POSTEMBRYONIC DEVELOPMENT
541 CHAPTER 76 THE SAGA OF THE GERM LINE 583 PART IV SYSTEMS BIOLOGY
EXPANDING DEVELOPMENTAL BIOLOGY TO MEDICINE, ECOLOGY, AND EVOLUTION 617
CHAPTER 17 MEDICAL ASPECTS OF DEVELOPMENTAL BIOLOGY 625 CHAPTER 18
DEVELOPMENTAL PLASTICITY AND SYMBIOSIS 659 CHAPTER 19 DEVELOPMENTAL
MECHANISMS OF EVOLUTIONARY CHANGE 683 CONTENTS PARTI QUESTIONS
INTRODUCING DEVELOPMENTAL BIOLOGY 1 CHAPTER 1 DEVELOPMENTAL ANATOMY 5
THE CYCLE OF LIFE 6 A FROG S LIFE 6 GAMETOGENESIS AND FERTILIZATION 6
CLEAVAGE AND GASTRULATION 7 ORGANOGENESIS 10 METAMORPHOSIS AND
GAMETOGENESIS 11 HOW ARE YOU? 12 COMPARATIVE EMBRYOLOGY 12 EPIGENESIS
AND PREFORMATION 12 NAMING THE PARTS: THE PRIMARY GERM LAYERS AND EARLY
ORGANS 14 THE FOUR PRINCIPLES OF KARL ERNST VON BAER 16 KEEPING TRACK OF
MOVING CELLS: FATE MAPS AND CELL LINEAGES 17 FATE MAPS 19 DIRECT
OBSERVATION OF LIVING EMBRYOS 19 DYE MARKING 19 GENETIC LABELING 20
TRANSGENIC DNA CHIMERAS 22 EVOLUTIONARY EMBRYOLOGY 23 EMBRYONIC
HOMOLOGIES 24 MEDICAL EMBRYOLOGY AND TERATOLOGY 27 GENETIC MALFORMATIONS
AND SYNDROMES 27 DISRUPTIONS AND TERATOGENS 28 CHAPTER 2 DEVELOPMENTAL
GENETICS 31 EVIDENCE FOR GENOMIC EQUIVALENCE 32 * SIDELIGHTS &
SPECULATIONS THE BASIC TOOLS OF DEVELOPMENTAL GENETICS 32 DIFFERENTIAL
GENE TRANSCRIPTION 35 ANATOMY OF THE GENE: ACTIVE AND REPRESSED
CHROMATIN 36 ANATOMY OF THE GENE: EXONS AND INTRONS 37 ANATOMY OF THE
GENE: PROMOTERS AND ENHANCERS 39 TRANSCRIPTION FACTOR FUNCTION 42 *
SIDELIGHTS & SPECULATIONS REPROGRAMMING CELLS: CHANGING CELL
DIFFERENTIATION THROUGH EMBRYONIC TRANSCRIPTION FACTORS 45 DNA
METHYLATION AND THE CONTROL OF TRANSCRIPTION 48 MECHANISMS BY WHICH DNA
METHYLATION BLOCKS TRANSCRIPTION 49 INHERITANCE AND STABILIZATION OF DNA
METHYLATION PATTERNS 49 * SIDELIGHTS & SPECULATIONS CONSEQUENCES OF DNA
METHYLATION 50 DIFFERENTIAL RNA PROCESSING 53 CONTROL OF EARLY
DEVELOPMENT BY NUCLEAR RNA SELECTION 53 CREATING FAMILIES OF PROTEINS
THROUGH DIFFERENTIAL NRNA SPLICING 54 VIII CONTENTS SPLICING ENHANCERS
AND RECOGNITION FACTORS 56 CONTROL OF GENE EXPRESSION AT THE LEVEL OF
TRANSLATION 58 DIFFERENTIAL MRNA LONGEVITY 58 SELECTIVE INHIBITION OF
MRNA TRANSLATION: STORED OOCYTE MRNAS 58 MICRORNAS: SPECIFIC REGULATORS
OF MRNA TRANSLATION AND TRANSCRIPTION 61 * SIDELIGHTS & SPECULATIONS
MICRORNAS IN TRANSCRIPTIONAL GENE REGULATION 63 CONTROL OF RNA
EXPRESSION BY CYTOPLASMIC LOCALIZATION 64 STORED MRNAS IN BRAIN CELLS 65
POSTTRANSLATIONAL REGULATION OF GENE EXPRESSION 66 CHAPTER 3 CELL-CELL
COMMUNICATION IN DEVELOPMENT 69 CELL ADHESION 70 DIFFERENTIAL CELL
AFFINITY 70 THE THERMODYNAMIC MODEL OF CELL INTERACTIONS 72 CADHERINS
AND CELL ADHESION 73 * SIDELIGHTS & SPECULATIONS SHAPE CHANGE AND
EPITHELIAL MORPHOGENESIS: THE FORCE IS STRONG IN YOU 76 CELL MIGRATION
78 CELL SIGNALING 79 INDUCTION AND COMPETENCE 79 CASCADES OF INDUCTION:
RECIPROCAL AND SEQUENTIAL INDUCTIVE EVENTS 80 INSTRUCTIVE AND PERMISSIVE
INTERACTIONS 81 EPITHELIAL-MESENCHYMAL INTERACTIONS 82 PARACRINE
FACTORS: THE INDUCER MOLECULES 84 SIGNAL TRANSDUCTION CASCADES: THE
RESPONSE TO INDUCERS 85 FIBROBLAST GROWTH FACTORS AND THE RTK PATHWAY 85
THE JAK-STAT PATHWAY 88 THE HEDGEHOG FAMILY 90 THE WNT FAMILY 92 THE
TGF-P SUPERFAMILY 94 OTHER PARACRINE FACTORS 95 * SIDELIGHTS &
SPECULATIONS CELL DEATH PATHWAYS 96 JUXTACRINE SIGNALING 98 THE NOTCH
PATHWAY: JUXTAPOSED LIGANDS AND RECEPTORS 98 * SIDELIGHTS & SPECULATIONS
JUXTACRINE SIGNALING AND CELL PATTERNING 99 MAINTAINING THE
DIFFERENTIATED STATE 101 THE EXTRACELLULAR MATRIX AS A SOURCE OF
DEVELOPMENTAL SIGNALS 102 INTEGRINS: RECEPTORS FOR EXTRACELLULAR MATRIX
MOLECULES 102 EPITHELIAL-MESENCHYMAL TRANSITION 105 PART SPECIFICATION
INTRODUCING CELL COMMITMENT AND EARLY EMBRYONIC DEVELOPMENT 109 LEVELS
OF COMMITMENT 109 AUTONOMOUS SPECIFICATION 110 CONDITIONAL SPECIFICATION
112 CHAPTER 4 FERTILIZATION: BEGINNING A NEW ORGANISM 121 STRUCTURE OF
THE GAMETES 121 SPERM 121 THE EGG 125 RECOGNITION OF EGG AND SPERM 127
MORPHOGEN GRADIENTS AND CELL SPECIFICATION 116 SYNCYTIAL SPECIFICATION
117 SUMMARY 119 EXTERNAL FERTILIZATION IN SEA URCHINS 127 SPERM
ATTRACTION: ACTION AT A DISTANCE 128 THE ACROSOME REACTION 130
RECOGNITION OF THE EGG S EXTRACELLULAR COAT 131 FUSION OF THE EGG AND
SPERM CELL MEMBRANES 133 THE FAST BLOCK TO POLYSPERMY 135 THE SLOW BLOCK
TO POLYSPERMY 136 CALCIUM AS THE INITIATOR OF THE CORTICAL GRANULE
REACTION 137 CONTENTS IX ACTIVATION OF EGG METABOLISM IN SEA URCHINS 139
RELEASE OF INTRACELLULAR CALCIUM IONS 139 EFFECTS OF CALCIUM 142 *
SIDELIGHTS & SPECULATIONS RULES OF EVIDENCE: FIND IT, LOSE IT, MOVE IT
144 FUSION OF GENETIC MATERIAL 145 INTERNAL FERTILIZATION IN MAMMALS 145
GETTING THE GAMETES INTO THE OVIDUCT: TRANSLOCATION AND CAPACITATION 145
IN THE VICINITY OF THE OOCYTE: HYPERACTIVATION, THERMOTAXIS, AND
CHEMOTAXIS 148 RECOGNITION AT THE ZONA PELLUCIDA 149 GAMETE FUSION AND
THE PREVENTION OF POLYSPERMY 152 FUSION OF GENETIC MATERIAL 153 *
SIDELIGHTS & SPECULATIONS THE NONEQUIVALENCE OF MAMMALIAN PRONUCLEI 154
ACTIVATION OF THE MAMMALIAN EGG 155 CODA 155 CHAPTER 5 EARLY DEVELOPMENT
IN SELECTED INVERTEBRATES 159 EARLY DEVELOPMENTAL PROCESSES: AN OVERVIEW
159 CLEAVAGE 159 FROM FERTILIZATION TO CLEAVAGE 160 THE CYTOSKELETAL
MECHANISMS OF MITOSIS 161 PATTERNS OF EMBRYONIC CLEAVAGE 162
GASTRULATION 162 CELL SPECIFICATION AND AXIS FORMATION 164 EARLY
DEVELOPMENT IN SEA URCHINS 165 SEA URCHIN CLEAVAGE 165 BLASTULA
FORMATION 166 FATE MAPS AND THE DETERMINATION OF SEA URCHIN BLASTOMERES
166 GLOBAL REGULATORY NETWORKS AND SKELETOGENIC MESENCHYME SPECIFICATION
167 SPECIFICATION OF THE VEGETAL CELLS 171 AXIS SPECIFICATION 172 SEA
URCHIN GASTRULATION 172 INGRESSION OF THE SKELETOGENIC MESENCHYME 172
INVAGINATION OF THE ARCHENTERON 176 EARLY DEVELOPMENT IN SNAILS 178
CLEAVAGE IN SNAIL EMBRYOS 178 THE SNAIL FATE MAP 181 THE POLAR LOBE:
CELL DETERMINATION AND AXIS FORMATION 182 GASTRULATION IN SNAILS 185 *
SIDELIGHTS & SPECULATIONS ADAPTATION BY MODIFYING EMBRYONIC CLEAVAGE 186
EARLY DEVELOPMENT IN TUNICATES 187 TUNICATE CLEAVAGE 187 THE TUNICATE
FATE MAP 187 AUTONOMOUS AND CONDITIONAL SPECIFICATION OF TUNICATE
BLASTOMERES 188 SPECIFICATION OF THE EMBRYONIC AXES 191 GASTRULATION IN
TUNICATES 191 THENEMATODEC.EUEGANS 192 CLEAVAGE AND AXIS FORMATION IN C.
ELEGANS 193 ROTATIONAL CLEAVAGE OF THE C. ELEGANS EGG 193
ANTERIOR-POSTERIOR AXIS FORMATION 193 FORMATION OF THE DORSAL-VENTRAL
AND RIGHT-LEFT AXES 196 CONTROL OF BLASTOMERE IDENTITY 197 GASTRULATION
IN C. ELEGANS 199 CODA 200 CHAPTER 6 THE GENETICS OF AXIS SPECIFICATION
IN DROSOPHILA 203 EARLY DROSOPHILA DEVELOPMENT 204 FERTILIZATION 204
CLEAVAGE 204 THE MID-BLASTULA TRANSITION 205 GASTRULATION 206 GENES THAT
PATTERN THE DROSOPHILA BODY PLAN 208 PRIMARY AXIS FORMATION DURING
OOGENESIS 209 ANTERIOR-POSTERIOR POLARITY IN THE OOCYTE 209
DORSAL-VENTRAL PATTERNING IN THE OOCYTE 211 GENERATING THE
DORSAL-VENTRAL PATTERN IN THE EMBRYO 213 DORSAL, THE VENTRAL MORPHOGEN
213 ESTABLISHING A NUCLEAR DORSAL GRADIENT 214 EFFECTS OF THE DORSAL
PROTEIN GRADIENT 214 * SIDELIGHTS & SPECULATIONS THE LEFT-RIGHT AXIS 217
SEGMENTATION AND THE ANTERIOR-POSTERIOR BODY PLAN 218 MATERNAL
GRADIENTS: POLARITY REGULATION BY OOCYTE CYTOPLASM 219 THE MOLECULAR
MODEL: PROTEIN GRADIENTS IN THE EARLY EMBRYO 219 CONTENTS THE ANTERIOR
ORGANIZING CENTER: THE BICOID AND HUNCHBACK GRADIENTS 223 THE TERMINAL
GENE GROUP 225 SUMMARIZING EARLY ANTERIOR-POSTERIOR AXIS SPECIFICATION
IN DROSOPHILA 226 SEGMENTATION GENES 226 * SIDELIGHTS & SPECULATIONS
SEGMENTS AND PARASEGMENTS 227 THE GAP GENES 228 THE PAIR-RULE GENES* 229
THE SEGMENT POLARITY GENES 231 THE HOMEOTIC SELECTOR GENES 234
INITIATING AND MAINTAINING THE PATTERNS OF HOMEOTIC GENE EXPRESSION 235
REALISATOR GENES 236 AXES AND ORGAN PRIMORDIA: THE CARTESIAN COORDINATE
MODEL 236 CODA 237 CHAPTER 7 AMPHIBIANS AND FISH: EARLY DEVELOPMENT AND
AXIS FORMATION 241 EARLY AMPHIBIAN DEVELOPMENT 242 FERTILIZATION,
CORTICAL ROTATION, AND CLEAVAGE 242 UNEQUAL RADIAL HOLOBLASTIC CLEAVAGE
243 THE MID-BLASTULA TRANSITION: PREPARING FOR GASTRULATION 244
AMPHIBIAN GASTRULATION 244 VEGETAL ROTATION AND THE INVAGINATION OF THE
BOTTLE CELLS 245 * SIDELIGHTS & SPECULATIONS FIBRONECTIN AND THE
PATHWAYS FOR MESODERMAL MIGRATION 250 EPIBOLY OF THE PROSPECTIVE
ECTODERM 251 PROGRESSIVE DETERMINATION OF THE AMPHIBIAN AXES 252 HANS
SPEMANN: INDUCTIVE INTERACTIONS IN REGULATIVE DEVELOPMENT 253 HANS
SPEMANN AND HILDE MANGOLD: PRIMARY EMBRYONIC INDUCTION 255 MOLECULAR
MECHANISMS OF AMPHIBIAN AXIS FORMATION 256 HOW DOES THE ORGANIZER FORM?
257 FUNCTIONS OF THE ORGANIZER 262 INDUCTION OF NEURAL ECTODERM AND
DORSAL MESODERM: BMP INHIBITORS 263 EPIDERMAL INDUCERS: THE BMPS 265 *
SIDELIGHTS & SPECULATIONS BMP4 AND GEOFFREY S LOBSTER 267 THE REGIONAL
SPECIFICITY OF NEURAL INDUCTION 267 THE HEAD INDUCER: WNT INHIBITORS 268
TRUNK PATTERNING: WNT SIGNALS AND RETINOIC ACID 270 SPECIFYING THE
LEFT-RIGHT AXIS 272 EARLY ZEBRAFISH DEVELOPMENT 273 CLEAVAGE 275
GASTRULATION AND FORMATION OF THE GERM LAYERS 277 AXIS FORMATION IN
ZEBRAFISH 278 DORSAL-VENTRAL AXIS FORMATION 278 THE FISH NIEUWKOOP
CENTER 281 ANTERIOR-POSTERIOR AXIS FORMATION 282 LEFT-RIGHT AXIS
FORMATION 282 CODA 283 CHAPTER 8 BIRDS AND MAMMALS: EARLY DEVELOPMENT
AND AXIS FORMATION 287 EARLY DEVELOPMENT IN BIRDS 287 CLEAVAGE 287
GASTRULATION OF THE AVIAN EMBRYO 288 THEHYPOBLAST 288 THE PRIMITIVE
STREAK 288 MOLECULAR MECHANISMS OF MIGRATION THROUGH THE PRIMITIVE
STREAK 292 REGRESSION OF THE PRIMITIVE STREAK AND EPIBOLY OF THE
ECTODERM 293 AXIS SPECIFICATION AND THE AVIAN ORGANIZER 295 THE ROLE
OF GRAVITY AND THE PMZ 295 THE CHICK ORGANIZER 296 ANTERIOR-POSTERIOR
PATTERNING 297 LEFT-RIGHT AXIS FORMATION 298 EARLY MAMMALIAN DEVELOPMENT
300 CLEAVAGE 300 THE UNIQUE NATURE OF MAMMALIAN CLEAVAGE 300 COMPACTION
301 * SIDELIGHTS & SPECULATIONS TROPHOBLAST OR ICM? 302 ESCAPE FROM THE
ZONA PELLUCIDA 304 MAMMALIAN GASTRULATION 304 MODIFICATIONS FOR
DEVELOPMENT INSIDE ANOTHER ORGANISM 305 FORMATION OF THE EXTRAEMBRYONIC
MEMBRANES 307 * SIDELIGHTS & SPECULATIONS TWINS AND CHIMERAS 309
CONTENTS XI MAMMALIAN AXIS FORMATION 311 THE ANTERIOR-POSTERIOR AXIS:
TWO SIGNALING CENTERS 311 ANTERIOR-POSTERIOR PATTERNING BY FGF AND
RETINOIC ACID GRADIENTS 312 ANTERIOR-POSTERIOR PATTERNING: THE HOX CODE
HYPOTHESIS 314 EXPERIMENTAL ANALYSIS OF THE HOX CODE 315 THE
DORSAL-VENTRAL AND LEFT-RIGHT AXES 316 THE DORSAL-VENTRAL AXIS 316 THE
LEFT-RIGHT AXIS 317 CODA 319 PART THE STEM CELL CONCEPT INTRODUCING
ORGANOGENESIS 323 THE STEM CELL CONCEPT 323 STEM CELL VOCABULARY 326
ADULT STEM CELLS 327 ADULT STEM CELL NICHES 328 MESENCHYMAL STEM CELLS:
MULTIPOTENT ADULT STEM CELLS 330 A NEW PERSPECTIVE ON ORGANOGENESIS 331
CHAPTER 9 THE EMERGENCE OF THE ECTODERM: CENTRAL NERVOUS SYSTEM AND
EPIDERMIS 333 ESTABLISHING THE NEURAL CELLS 333 CONSTRUCTING THE CENTRAL
NERVOUS SYSTEM 334 FORMATION OF THE NEURAL TUBE 334 PRIMARY NEURULATION
335 SECONDARY NEURULATION 340 BUILDING THE BRAIN 341 DIFFERENTIATION OF
THE NEURAL TUBE 341 THE ANTERIOR-POSTERIOR AXIS 341 THE DORSAL-VENTRAL
AXIS 343 DIFFERENTIATION OF NEURONS IN THE BRAIN 345 TISSUE ARCHITECTURE
OF THE CENTRAL NERVOUS SYSTEM 348 SPINAL CORD AND MEDULLA ORGANIZATION
349 CEREBELLAR ORGANIZATION 350 CEREBRAL ORGANIZATION 351 * SIDELIGHTS &
SPECULATIONS ADULT NEURAL STEM CELLS 354 * SIDELIGHTS & SPECULATIONS THE
UNIQUE DEVELOPMENT OF THE HUMAN BRAIN 356 DEVELOPMENT OF THE VERTEBRATE
EYE 359 THE DYNAMICS OF OPTIC DEVELOPMENT 359 FORMATION OF THE EYE FIELD
359 CELL DIFFERENTIATION IN THE VERTEBRATE EYE 362 NEURAL RETINA
DIFFERENTIATION 362 LENS AND CORNEA DIFFERENTIATION 364 THE EPIDERMIS
AND ITS CUTANEOUS APPENDAGES 365 ORIGIN OF THE EPIDERMIS 365 THE
CUTANEOUS APPENDAGES 366 * SIDELIGHTS & SPECULATIONS EDAR SYNDROMES 369
CHAPTER 10 NEURAL CREST CELLS ANDAXONAL SPECIFICITY 373 THE NEURAL CREST
373 SPECIFICATION OF NEURAL CREST CELLS 374 REGIONALIZATION OF THE
NEURAL CREST 376 TRUNK NEURAL CREST 377 MIGRATION PATHWAYS OF TRUNK
NEURAL CREST CELLS 377 THE MECHANISMS OF TRUNK NEURAL CREST MIGRATION
378 THE VENTRAL PATHWAY 379 THE DORSOLATERAL MIGRATION PATHWAY 382
CRANIAL NEURAL CREST 383 INTRAMEMBRANOUS OSSIFICATION: NEURAL
CREST-DERIVED HEAD SKELETON 385 COORDINATION OF FACE AND BRAIN GROWTH
387 TOOTH FORMATION 388 CARDIAC NEURAL CREST 388 XII CONTENTS CRANIAL
PLACODES 389 * SIDELIGHTS & SPECULATIONS CRANIAL NEURAL CREST CELL
MIGRATION AND SPECIFICATION 391 NEURONAL SPECIFICATION AND AXONAL
SPECIFICITY 392 THE GENERATION OF NEURONAL DIVERSITY 393 PATTERN
GENERATION IN THE NERVOUS SYSTEM 394 CELL ADHESION AND CONTACT GUIDANCE
BY ATTRACTION AND REPULSION 396 GUIDANCE BY DIFFUSIBLE MOLECULES 398
TARGET SELECTION 399 FORMING THE SYNAPSE: ACTIVITY-DEPENDENT DEVELOPMENT
402 DIFFERENTIAL SURVIVAL AFTER INNERVATION: NEUROTROPHIC FACTORS 403 *
SIDELIGHTS & SPECULATIONS THE BRAINBOW 404 PATHS TO GLORY: THE TRAVELS
OF THE RETINAL GANGLION AXONS 404 THE DEVELOPMENT OF BEHAVIORS:
CONSTANCY AND PLASTICITY 408 CHAPTER 11 PARAXIAL AND INTERMEDIATE
MESODERM 413 PARAXIAL MESODERM: THE SOMITES AND THEIR DERIVATIVES 414
FORMATION OF THE SOMITES 415 PERIODICITY OF SOMITE FORMATION 417 WHERE
SOMITES FORM: THE NOTCH PATHWAY 417 * SIDELIGHTS & SPECULATIONS
COORDINATING WAVES AND CLOCKS IN SOMITE FORMATION 419 SEPARATION OF
SOMITES FROM THE UNSEGMENTED MESODERM 420 EPITHELIALIZATION OF THE
SOMITES 420 SOMITE SPECIFICATION ALONG THE ANTERIOR-POSTERIOR AXIS 420
DIFFERENTIATION OF THE SOMITES 421 DETERMINATION OF THE SCLEROTOME 424
DETERMINATION OF THE CENTRAL DERMAMYOTOME 425 DETERMINATION OF THE
MYOTOME 425 MYOGENESIS: THE GENERATION OF MUSCLE 426 MYOGENIC BHLH
PROTEINS 426 SPECIFICATION OF MUSCLE PROGENITOR CELLS 426 MYOBLAST
FUSION 427 OSTEOGENESIS: THE DEVELOPMENT OF BONES 428 ENDOCHONDRAL
OSSIFICATION 428 VERTEBRAE FORMATION 431 DORSAL AORTA FORMATION 432
TENDON FORMATION: THE SYNDETOME 432 INTERMEDIATE MESODERM: THE
UROGENITAL SYSTEM 434 THE PROGRESSION OF KIDNEY TYPES 434 SPECIFICATION
OF THE INTERMEDIATE MESODERM: PAX2/8 AND LIM1 435 RECIPROCAL
INTERACTIONS OF DEVELOPING KIDNEY TISSUES 436 MECHANISMS OF RECIPROCAL
INDUCTION 437 CODA 442 CHAPTER 12 LATERAL PLATE MESODERM AND THE
ENDODERM 445 LATERAL PLATE MESODERM 445 HEART DEVELOPMENT 446
SPECIFICATION OF HEART TISSUE 446 MIGRATION OF CARDIAC PRECURSOR CELLS
448 DETERMINATION OF ANTERIOR AND POSTERIOR CARDIAC DOMAINS 450 HEART
CELL DIFFERENTIATION 450 FUSION OF THE HEART RUDIMENTS AND INITIAL
HEARTBEATS 452 LOOPING AND FORMATION OF HEART CHAMBERS 453 * SIDELIGHTS
& SPECULATIONS REDIRECTING BLOOD FLOW IN THE NEWBORN MAMMAL 455
FORMATION OF BLOOD VESSELS 456 CONSTRAINTS ON THE CONSTRUCTION OF BLOOD
VESSELS 456 VASCULOGENESIS: THE INITIAL FORMATION OF BLOOD VESSELS 458
ANGIOGENESIS: SPROUTING OF BLOOD VESSELS AND REMODELING OF VASCULAR BEDS
461 ARTERIAL AND VENOUS DIFFERENTIATION 462 ORGAN-SPECIFIC CAPILLARY
FORMATION 463 ANTI-ANGIOGENESIS IN NORMAL AND ABNORMAL DEVELOPMENT 465
THE LYMPHATIC VESSELS 465 HEMATOPOIESIS: THE STEM CELL CONCEPT 466 SITES
OF HEMATOPOIESIS 466 COMMITTED STEM CELLS AND THEIR FATES 468
HEMATOPOIETIC INDUCTIVE MICROENVIRONMENTS 470 STEM CELL NICHE
CONSTRUCTION 470 CONTENTS XIII ENDODERM 471 THE PHARYNX 471 THE
DIGESTIVE TUBE AND ITS DERIVATIVES 473 SPECIFICATION OF THE GUT TISSUE
473 LIVER, PANCREAS, AND GALLBLADDER 475 * SIDELIGHTS & SPECULATIONS
SPECIFICATION OF LIVER AND PANCREAS 476 THE RESPIRATORY TUBE 478 THE
EXTRAEMBRYONIC MEMBRANES 480 THE ARRMION AND CHORION 481 THE ALLANTOIS
AND YOLK SAC 482 CHAPTER 13 DEVELOPMENT OF THE TETRAPOD LIMB 485
FORMATION OF THE LIMB BUD 486 SPECIFICATION OF THE LIMB FIELDS 486
INDUCTION OF THE EARLY LIMB BUD: WNT PROTEINS AND FIBROBLAST GROWTH
FACTORS 488 SPECIFICATION OF FORELIMB OR HINDLIMB 488 GENERATING THE
PROXIMAL-DISTAL AXIS OF THE LIMB 491 THE APICAL ECTODERMAL RIDGE 491
FGFS IN THE INDUCTION OF THE AER 492 SPECIFYING THE LIMB MESODERM:
DETERMINING THE PROXIMAL-DISTAL POLARITY OF THE LIMB 493 A
REACTION-DIFFUSION MODEL FOR LIMB SPECIFICATION 494 SPECIFICATION OF THE
ANTERIOR-POSTERIOR AXIS 495 THE ZONE OF POLARIZING ACTIVITY 495 *
SIDELIGHTS & SPECULATIONS HOX GENE CHANGES DURING LIMB DEVELOPMENT 498
SPECIFYING DIGIT IDENTITY BY SONIC HEDGEHOG 500 GENERATION OF THE
DORSAL-VENTRAL AXIS 502 COORDINATING THE THREE AXES 502 CELL DEATH AND
THE FORMATION OF DIGITS AND JOINTS 504 SCULPTING THE AUTOPOD 504 *
SIDELIGHTS & SPECULATIONS LIMB DEVELOPMENT AND EVOLUTION 505 FORMING THE
JOINTS 507 CONTINUED LIMB GROWTH: EPIPHYSEAL PLATES 508 FIBROBLAST
GROWTH FACTOR RECEPTORS: DWARFISM 508 GROWTH HORMONE AND ESTROGEN
RECEPTORS 509 PARATHYROID HORMONE-RELATED PEPTIDE AND INDIAN HEDGEHOG
509 CODA 509 CHAPTER 14 SEX DETERMINATION 511 CHROMOSOMAL SEX
DETERMINATION 512 THE MAMMALIAN PATTERN: PRIMARY AND SECONDARY SEX
DETERMINATION 512 PRIMARY SEX DETERMINATION IN MAMMALS 513 THE
DEVELOPING GONADS 513 MECHANISMS OF MAMMALIAN PRIMARY SEX DETERMINATION:
MAKING DECISIONS 515 THE OVARY PATHWAY: WNT4 AND R-SPONDINL 517 THE
TESTIS PATHWAY 518 THE RIGHT TIME AND THE RIGHT PLACE 521 * SIDELIGHTS &
SPECULATIONS MYSTERIES OF GONAD DIFFERENTIATION 521 SECONDARY SEX
DETERMINATION IN MAMMALS: HORMONAL REGULATION OF THE SEXUAL PHENOTYPE
523 THE GENETIC ANALYSIS OF SECONDARY SEX DETERMINATION 523 BRAIN SEX:
SECONDARY SEX DETERMINATION THROUGH ANOTHER PATHWAY? 525 * SIDELIGHTS &
SPECULATIONS BRAIN SEX: SEX DETERMINANTS AND BEHAVIORS IN MICE AND RATS
526 CHROMOSOMAL SEX DETERMINATION IN DROSOPHILA 529 THE SEX-LETHAL GENE
529 DOUBLESEX: THE SWITCH GENE FOR SEX DETERMINATION 532 BRAIN SEX IN
DROSOPHILA 533 DOSAGE COMPENSATION 534 ENVIRONMENTAL SEX DETERMINATION
534 TEMPERATURE-DEPENDENT SEX DETERMINATION IN REPTILES 534 THE
AROMATASE HYPOTHESIS FOR ENVIRONMENTAL SEX DETERMINATION 535 ESTROGENS,
AROMATASE, SEX REVERSAL, AND CONSERVATION BIOLOGY 535 LOCATION-DEPENDENT
SEX DETERMINATION 536 CODA 538 XIV CONTENTS CHAPTER 15 POSTEMBRYONIC
DEVELOPMENT: METAMORPHOSIS, REGENERATION, AND AGING 547 METAMORPHOSIS:
THE HORMONAL REACTIVATION OF DEVELOPMENT 541 AMPHIBIAN METAMORPHOSIS 542
MORPHOLOGICAL CHANGES ASSOCIATED WITH AMPHIBIAN METAMORPHOSIS 542
HORMONAL CONTROL OF AMPHIBIAN METAMORPHOSIS 545 REGIONALLY SPECIFIC
DEVELOPMENTAL PROGRAMS 547 * SIDELIGHTS & SPECULATIONS VARIATIONS ON THE
THEME OF AMPHIBIAN METAMORPHOSIS 548 METAMORPHOSIS IN INSECTS 550
IMAGINAL DISCS 551 DETERMINATION OF THE WING IMAGINAL DISCS 554 HORMONAL
CONTROL OF INSECT METAMORPHOSIS 556 THE MOLECULAR BIOLOGY OF
20-HYDROXYECDYSONE ACTIVITY 556 REGENERATION 560 EPIMORPHIC REGENERATION
OF SALAMANDER LIMBS 561 FORMATION OF THE APICAL ECTODERMAL CAP AND
REGENERATION BLASTEMA 561 PROLIFERATION OF THE BLASTEMA CELLS: THE
REQUIREMENT FOR NERVES AND THE AEC 563 * SIDELIGHTS & SPECULATIONS HOW
DO THE BLASTEMA CELLS KNOW THEIR PROXIMAL AND DISTAL LEVELS? 564
MORPHALLACTIC REGENERATION IN HYDRA 566 THE HEAD ACTIVATION GRADIENT 567
THE HEAD INHIBITION GRADIENT 567 THE HYPOSTOME AS AN ORGANIZER 568 THE
BASAL DISC ACTIVATION AND INHIBITION GRADIENTS 569 COMPENSATORY
REGENERATION IN THE MAMMALIAN LIVER 570 AGING: THE BIOLOGY OF SENESCENCE
571 GENES AND AGING 571 GENES ENCODING DNA REPAIR PROTEINS 571 AGING AND
THE INSULIN SIGNALING CASCADE 573 INTEGRATING THE CONSERVED AGING
PATHWAYS 575 ENVIRONMENTAL AND EPIGENETIC CAUSES OF AGING 575 *
SIDELIGHTS & SPECULATIONS EXCEPTIONS TO THE AGING RULE 579 PROMOTING
LONGEVITY 579 CHAPTER 16 THE SAGA OF THE GERM LINE 583 GERM PLASM AND
THE DETERMINATION OF THE PRIMORDIAL GERM CELLS 583 GERM CELL
DETERMINATION IN NEMATODES 584 GERM CELL DETERMINATION IN INSECTS 585
GERM CELL DETERMINATION IN FROGS AND FISH 588 GERM CELL DETERMINATION IN
MAMMALS 588 THE INERT GENOME HYPOTHESIS 589 * SIDELIGHTS & SPECULATIONS
PLURIPOTENCY, GERM CELLS, AND EMBRYONIC STEM CELLS 590 GERM CELL
MIGRATION 592 GERM CELL MIGRATION IN DROSOPHILA 592 GERM CELL MIGRATION
IN VERTEBRATES 594 MEIOSIS 598 * SIDELIGHTS & SPECULATIONS BIG
DECISIONS: MITOSIS OR MEIOSIS? SPERM OR EGG? 600 GAMETE MATURATION 602
MATURATION OF THE OOCYTES IN FROGS 603 GENE TRANSCRIPTION IN AMPHIBIAN
OOCYTES 604 MEROISTIC OOGENESIS IN INSECTS 606 GAMETOGENESIS IN MAMMALS
607 SPERMATOGENESIS 607 OOGENESIS 610 CODA 613 CONTENTS XV PART | /
SYSTEMS BIOLOGY EXPANDING I / DEVELOPMENTAL BIOLOGY TO MEDICINE,
ECOLOGY AND EVOLUTION 617 CONTEXT-DEPENDENT PROPERTIES 619 EMERGENCE 6^9
LEVEL-SPECIFIC RULES 620 HETEROGENEOUS CAUSATION 620 INTEGRATION 621
MODULES AND ROBUSTNESS 622 CHAPTER 17 MEDICAL ASPECTS OF DEVELOPMEN TAL
BIOLOGY 625 DISEASES OF DEVELOPMENT 626 GENETIC ERRORS OF HUMAN
DEVELOPMENT 626 THE NATURE OF HUMAN SYNDROMES 627 GENETIC HETEROGENEITY
AND PHENOTYPIC HETEROGENEITY 628 TERATOGENESIS: ENVIRONMENTAL ASSAULTS
ON HUMAN DEVELOPMENT 628 * SIDELIGHTS & SPECULATIONS PRENATAL DIAGNOSIS
AND PREIMPLANTATION GENETICS 629 ALCOHOL AS A TERATOGEN 631 RETINOIC
ACID AS A TERATOGEN 633 ENDOCRINE DISRUPTORS 634 OTHER TERATOGENIC
AGENTS 639 * SIDELIGHTS & SPECULATIONS TESTICULAR DYSGENESIS SYNDROME
AND THE TRANSGENERATIONAL EFFECTS OF ENDOCRINE DISRUPTORS 640 CANCER AS
A DISEASE OF DEVELOPMENT 643 CONTEXT-DEPENDENT RUMORS 643 THE CANCER
STEM CELL HYPOTHESIS: CANCER AS A DISEASE OF STEM CELL REGULATION 644
CANCER AS A RETURN TO EMBRYONIC INVASIVENESS: MIGRATION REACTIVATED 645
CANCER AND EPIGENETIC GENE REGULATION 645 * SIDELIGHTS & SPECULATIONS
THE EMBRYONIC ORIGINS OF ADULT-ONSET ILLNESSES 646 DEVELOPMENTAL
THERAPIES 648 ANTI-ANGIOGENESIS 648 STEM CELLS AND TISSUE REGENERATION
649 EMBRYONIC STEM CELLS 649 INDUCED PLURIPOTENT STEM CELLS 651 ADULT
STEM CELLS AND REGENERATION THERAPY 653 DIRECT TRANSDIFFERENTIATION 655
CODA 655 CHAPTER 18 DEVELOPMENTAL PLASTICITY AND SYMBIOSIS 659 THE
ENVIRONMENT AS A NORMAL AGENT IN PRODUCING PHENOTYPES 659 DIET-INDUCED
POLYPHENISMS 661 PREDATOR-INDUCED POLYPHENISMS 663 TEMPERATURE AS AN
ENVIRONMENTAL AGENT 664 ENVIRONMENTAL INDUCTION OF BEHAVIORAL PHENOTYPES
667 ADULT ANXIETY AND ENVIRONMENTALLY REGULATED DNA METHYLATION 667
LEARNING: THE DEVELOPMENTALLY PLASTIC NERVOUS SYSTEM 667 EXPERIENTIAL
CHANGES IN MAMMALIAN VISUAL PATHWAYS 668 LIFE CYCLES AND POLYPHENISMS
670 DIAPAUSE 670 LARVAL SETTLEMENT 670 THE SPADEFOOT TOAD: A HARD LIFE
671 * SIDELIGHTS & SPECULATIONS LIFE CYCLE CHOICES: DICTYOSTELIUM 672
DEVELOPMENTAL SYMBIOSES 675 MECHANISMS OF DEVELOPMENTAL SYMBIOSIS:
GETTING THE PARTNERS TOGETHER 676 THE EUPRYMNA-VIBRIO SYMBIOSIS 677
OBLIGATE DEVELOPMENTAL MUTUALISM 677 SYMBIOSIS IN THE MAMMALIAN
INTESTINE 678 CODA 680 XVI CONTENTS CHAPTER 19 DEVELOPMENTAL MECHANISMS
OF EVOLUTIONARY CHANGE 683 UNITY OF TYPE AND CONDITIONS OF
EXISTENCE : CHARLES DARWIN S SYNTHESIS 683 PRECONDITIONS FOR EVOLUTION
THROUGH DEVELOPMENTAL CHANGE 684 MODULARITY: DIVERGENCE THROUGH
DISSOCIATION 684 MOLECULAR PARSIMONY: GENE DUPLICATION AND DIVERGENCE
686 DEEP HOMOLOGY 688 MECHANISMS OF EVOLUTIONARY CHANGE 689 HETEROTOPY
689 HETEROCHRONY 691 HETEROMETRY 692 HETEROTYPY 696 DEVELOPMENTAL
CONSTRAINTS ON EVOLUTION 697 PHYSICAL CONSTRAINTS 697 MORPHOGENETIC
CONSTRAINTS: THE REACTION-DIFFUSION MODEL 697 PHYLETIC CONSTRAINTS 700
SELECTABLE EPIGENETIC VARIATION 702 TRANSGENERATIONAL INHERITANCE OF
ENVIRONMENTALLY INDUCED TRAITS 702 GENETIC ASSIMILATION 705 * SIDELIGHTS
& SPECULATIONS HSP90 AND GENETIC ASSIMILATION 706 FIXATION OF
ENVIRONMENTALLY INDUCED PHENOTYPES 708 A DEVELOPMENTAL ACCOUNT OF
EVOLUTION 709 GLOSSARY G-1 CHAPTER-OPENING CREDITS C-1 AUTHOR INDEX A-1
SUBJECT INDEX S-1
|
| any_adam_object | 1 |
| author | Gilbert, Scott F. 1949- |
| author_GND | (DE-588)133098559 |
| author_facet | Gilbert, Scott F. 1949- |
| author_role | aut |
| author_sort | Gilbert, Scott F. 1949- |
| author_variant | s f g sf sfg |
| building | Verbundindex |
| bvnumber | BV036467018 |
| callnumber-first | Q - Science |
| callnumber-label | QL955 |
| callnumber-raw | QL955 |
| callnumber-search | QL955 |
| callnumber-sort | QL 3955 |
| callnumber-subject | QL - Zoology |
| classification_rvk | WX 6000 |
| ctrlnum | (OCoLC)699806683 (DE-599)BVBBV036467018 |
| dewey-full | 571.8 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 571 - Physiology & related subjects |
| dewey-raw | 571.8 |
| dewey-search | 571.8 |
| dewey-sort | 3571.8 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| edition | 9. ed. |
| format | Book |
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| genre | 1\p (DE-588)4123623-3 Lehrbuch gnd-content |
| genre_facet | Lehrbuch |
| id | DE-604.BV036467018 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:40:05Z |
| institution | BVB |
| isbn | 9780878933846 |
| language | English |
| lccn | 2010009918 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-020338783 |
| oclc_num | 699806683 |
| open_access_boolean | |
| owner | DE-20 DE-11 DE-29T DE-355 DE-BY-UBR DE-19 DE-BY-UBM DE-703 |
| owner_facet | DE-20 DE-11 DE-29T DE-355 DE-BY-UBR DE-19 DE-BY-UBM DE-703 |
| physical | Getr. Zählung Ill., graph. Darst. |
| publishDate | 2010 |
| publishDateSearch | 2010 |
| publishDateSort | 2010 |
| publisher | Sinauer |
| record_format | marc |
| spelling | Gilbert, Scott F. 1949- Verfasser (DE-588)133098559 aut Developmental biology Scott F. Gilbert 9. ed. Sunderland, MA Sinauer 2010 Getr. Zählung Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Embryology Developmental biology Embryologie (DE-588)4014562-1 gnd rswk-swf Entwicklungsphysiologie (DE-588)4152449-4 gnd rswk-swf Ontogenie (DE-588)4043565-9 gnd rswk-swf Entwicklungsbiologie (DE-588)4152440-8 gnd rswk-swf Embryonalentwicklung (DE-588)4070792-1 gnd rswk-swf Morphogenese (DE-588)4132460-2 gnd rswk-swf 1\p (DE-588)4123623-3 Lehrbuch gnd-content Entwicklungsbiologie (DE-588)4152440-8 s Morphogenese (DE-588)4132460-2 s Entwicklungsphysiologie (DE-588)4152449-4 s Embryologie (DE-588)4014562-1 s Ontogenie (DE-588)4043565-9 s 2\p DE-604 Embryonalentwicklung (DE-588)4070792-1 s 3\p DE-604 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020338783&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Gilbert, Scott F. 1949- Developmental biology Embryology Developmental biology Embryologie (DE-588)4014562-1 gnd Entwicklungsphysiologie (DE-588)4152449-4 gnd Ontogenie (DE-588)4043565-9 gnd Entwicklungsbiologie (DE-588)4152440-8 gnd Embryonalentwicklung (DE-588)4070792-1 gnd Morphogenese (DE-588)4132460-2 gnd |
| subject_GND | (DE-588)4014562-1 (DE-588)4152449-4 (DE-588)4043565-9 (DE-588)4152440-8 (DE-588)4070792-1 (DE-588)4132460-2 (DE-588)4123623-3 |
| title | Developmental biology |
| title_auth | Developmental biology |
| title_exact_search | Developmental biology |
| title_full | Developmental biology Scott F. Gilbert |
| title_fullStr | Developmental biology Scott F. Gilbert |
| title_full_unstemmed | Developmental biology Scott F. Gilbert |
| title_short | Developmental biology |
| title_sort | developmental biology |
| topic | Embryology Developmental biology Embryologie (DE-588)4014562-1 gnd Entwicklungsphysiologie (DE-588)4152449-4 gnd Ontogenie (DE-588)4043565-9 gnd Entwicklungsbiologie (DE-588)4152440-8 gnd Embryonalentwicklung (DE-588)4070792-1 gnd Morphogenese (DE-588)4132460-2 gnd |
| topic_facet | Embryology Developmental biology Embryologie Entwicklungsphysiologie Ontogenie Entwicklungsbiologie Embryonalentwicklung Morphogenese Lehrbuch |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020338783&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT gilbertscottf developmentalbiology |