RNA interference: from biology to clinical applications
Gespeichert in:
Bibliographische Detailangaben
Format: Buch
Sprache:English
Veröffentlicht: New York Humana Press 2010
Schriftenreihe:Methods in molecular biology 623
Schlagworte:
Beschreibung:Includes bibliographical references and index
Endogenous antiviral mechanisms of RNA interference : a comparative biology perspective / Abubaker M.E. Sidahmed and Bruce Wilkie -- Monitoring innate immune recruitment by siRNAs in mammalian cells / Michael P. Gantier and Bryan R.G. Williams -- Current knowledge of microRNAs and noncoding RNAs in virus-infected cells / Dominique L. Ouellet and Patrick Provost -- Allele-specific silencing by RNA interference / Hirohiko Hohjoh -- Computational siRNA design considering alternative splicing / Young J. Kim -- Bioinformatic approaches to siRNA selection and optimization / Pirkko Muhonen and Harry Holthofer -- Optimized gene silencing by co-expression of mulitple shRNAs in a single vector / Yasuhito Ishigaki, Akihiro Nagao, and Tsukasa Matsunaga -- Stratiges in designing multigene expression units to downregulate HIV-1 / Jane Zhang and John J. Rossi -- Designing optimal siRNA based on target site accessibility / Ivo L. Hofacker and Hakim Tafer -- Chemical syntheses of 2'-O-alkylated siRNAs / Joachim W. Engels ... [et al.] -- siRNA specific delivery system for targeting dendritic cells / Xiufen Zheng ... [et al.] -- Hydrodynamic delivery protocols / Piotr G. Rychahou and B. Mark Evers -- New methods for reverse transfection with siRNA from a solid surface / Satoshi Fujita ... [et al.] -- Nonviral siRNA delivery for gene silencing in neurodegenerative diseases / Satya Prakash, Meenakshi Malhotra, and Venkatesh Rengaswamy --
Using siRNA to uncover novel oncogenic signaling pathways / Jin-Mei Lai, Chi-Ying F. Huang, and Chang-Han Chen -- Biodegradable polymer-mediated sh/siRNA delivery for cancer studies / Dhananjay J. Jere and Chong-Su Cho -- Cellular siRNA delivery using TatU1A and photo-induced RNA interference / Tamaki Endoh and Takashi Ohtsuki -- Polyethylenimine (PEI)/siRNA-mediated gene knockdown in vitro and in vivo / Sabrina Höbel and Achim Aigner -- Transfection of siRNAs in multiple myeloma cell lines / Jose L.R. Brito, Nicola Brown, and Garth J. Morgan -- A new approach for therapeutic use by RNA interference in the brain / Yukio Akaneya -- Inhibitory RNA molecules in immunotherapy for cancer / Chih-Ping Mao and T.-C. Wu -- Preventing tissue injury using siRNA / Zhu-Xu Zhang ... [et al.] -- Preventing immune rejection through gene silencing / Xusheng Zhang, Mu Li, and Wei-Ping Min -- Topical application of siRNA targeting cutaneous dendritic cells in allergic skin disease / Miyuki Azuma, Patcharee Ritprajak, and Masaaki Hashiguchi -- Direct application of siRNA for in vivo pain research / Philippe Sarret, Louis Doré-Savard, and Nicolas Beaudet -- A potenetial therapeutic for pandemic influenza using RNA interference / Shaguna Seth ... [et al.] -- Evaluation of targets for ovarian cancer gene silencing therapy : in vitro and in vivo approaches / Anastasia Malek and Oleg Tchernitsa
Beschreibung:XVI, 450 S. Ill., graph. Darst. 27 cm

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