Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines:
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| Main Author: | |
|---|---|
| Format: | Thesis Book |
| Language: | English |
| Published: |
Gießen
DVG
2009
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| Edition: | 1. Aufl. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | 122 S. Ill., graph. Darst., Kt. 21 cm |
| ISBN: | 9783941703568 |
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| 242 | 0 | 0 | |a Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen |y ger |
| 245 | 1 | 0 | |a Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines |c von Astrid Martha Günther-Weigl |
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Record in the Search Index
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| adam_text | CONTENTS 1. INTRODUCTION 1 2. REVIEW OF UTERATURE 3 2.1 CANINE
DISTEMPER. 3 2.1.1 TAXONOMY 3 2.1.2 MORPHOLOGY 3 2.1.3 PROTEINS 5 2.1.4
PHYSICAL PROPERTIES. 6 2.1.5 GENOTYPES. 6 2.1.5.1 CDV VACCINE STRAINS 6
2.1.6 PATHOGENESIS AND CLINICAL SIGNS 8 2.1.7 EPIDEMIOLOGY. 9 2.1.8
CANINE DISTEMPER IN NON-DOMESTIC SPECIES 11 2.1.9 IMMUNE RESPONSE. 16
2.1.10 CDV DIAGNOSIS. 18 2.1.10.1 VIRUS DETECTION 18 2.1.10.2 ANTIBODY
DETECTION. 19 2.1.11 PREVENTION AND CONTROL. 21 2.2 CANINE DISTEMPER
VACCINATION. .22 2.2.1 PRINCIPLES OF VACCINATION. _ 22 2.2.2 CANINE
DISTEMPER VACCINES 22 2.2.2.1 MODIFIED LIVE VIRUS VACCINES 22 2.2.2.2
INACTIVATED VACCINE 24 2.2.2.3 CDV-ISCOM SUBUNIT VACCINE .25 2.2.2.4
RECOMBINANT VACCINES 25 2.2.2.5 DNA VACCINES. .26 2.2.3 VACCINATION
SCHEDULES .26 2.2.4 FAILURES IN VACCINATION 27 BIBLIOGRAFISCHE
INFORMATIONEN HTTP://D-NB.INFO/1000789950 DIGITALISIERT DURCH 5.3
MODIFIED LIVE VIRUS CDV VACCINES .53 CONTENTS 3. AIMS OF THE STUDY .29
4. MATERIALS AND METHODS .30 4.1 STUDY ANIMALS. 31 4.2 VACCINES AND
VACCINATION INTERVALS 32 4.3 IMMOBILISATION AND BLOOD-SAMPLING .33 4.4
LABORATORY DIAGNOSIS .34 4.4.1 PROCESSING OF BLOOD. .34 4.4.2 CELL
CULTURES .35 4.4.3 VIRUSES 35 4.4.4 NEUTRALISING PEROXIDASE-LINKED
ANTIBODY TEST (NPLAT) 35 4.4.5 INDIRECT ENZYME-LINKED MMONOSORBENT
ASSAY (ELISA). .37 4.4.6 EXPRESSING AND PRESENTING SEROLOGIE RESULTS.
.39 4.5 STATISTICAL ANALYSIS. .40 5. RESULTS. 41 STUDY 1: OTTERS
PREVIOUSLY NOT VACCINATED 5.1 INACTIVATED CDV VACCINE .41 5.1.1 SAMPLE
DISTRIBUTION. .41 5.1.2 PREVALENCE OF CDV-SPECIFIC ANTIBODIES .42 5.1.3
SERO-RESPONSE AFTER VACCINATION WITH INACTIVATED CDV VACCINE. 42 5.1.3.1
EURASIAN OTTER .42 5.1.3.2 NORTH AMERICAN RIVER OTTER. .44 5.1.3.3 ASIAN
SMALL-CLAWED OTTER. .44 5.1.4 COMPARISON OF SERO-RESPONSE TO INACTIVATED
CDV VACCINE IN THE THREE OTTER SPECIES. .47 5.2 CDV-ISCOM VACCINE. .47
5.2.1 SAMPLE DISTRIBUTION 47 5.2.2 PREVALENCE OF CDV-SPECIFIC ANTIBODIES
.48 5.2.3 SERO-RESPONSE AFTER VACCINATION WITH CDV-ISCOM VACCINE. .48
5.2.3.1 EURASIAN OTTERS. .48 5.2.3.2 ASIAN SMALL-CLAWED OTTERS .49
5.2.3.3 COMPARISON OF IMMUNE RESPONSE TO CDV-ISCOM VACCINE IN THE TWO
OTTER SPECIES. .50 CONTENTS 5.3.1 SAMPLE DISTRIBUTION .53 5.3.2
PREVALENCE OF CDV-SPECIFIC ANTIBODIES 54 5.3.3 SERO-RESPONSE AFTER
VACCINATION WITH MODIFIED LIVE VIRUS VACCINE. .54 5.3.3.1 EURASIAN
OTTERS. .54 5.3.3.2 ASIAN SMALL-CLAWED OTTERS 55 5.3.4 COMPARISON OF
SERO-RESPONSE TO MODIFIED LIVE VIRUS VACCINES BETWEEN THE TWO OTTER
SPECIES. .56 5.3.5 INFLUENCE OF VACCINE STRAIN ON SERO-RESPONSE 58
5.3.5.1 CHICKEN-CELL CULTURE ADAPTED VACCINE STRAIN IN EURASIAN OTTERS
AND ASIAN SMALL-CLAWED OTTERS. .58 5.3.5.2 DIFFERENT VACCINE STRAINS IN
EURASIAN OTTERS. .59 5.4 COMPARISON OF THE THREE VACCINE TYPES IN
EURASIAN OTTERS AND ASIAN SMALL- CLAWED OTTERS .61 5.5. COMPARISON OF
ELISA AND VIRUS NEUTRALISATION TEST .62 STUDY 2: BOOSTER VACCINATION 5.6
BOOSTER VACCINATION WITH MODIFIED LIVE VIRUS VACCINE IN EURASIAN OTTERS.
.63 5.6.1 SAMPLE DISTRIBUTION. .63 5.6.2 PREVALENCE OF CDV-SPECIFIC
ANTIBODIES .63 5.6.3 SERO-RESPONSE AFTER BOOSTER VACCINATION WITH
MODIFIED LIVE VIRUS VACCINE .64 6. DISCUSSION .66 6.1 CDV VACCINATION IN
OTTERS. .66 6.2 STATISTICS. .67 6.3 LABORATORY DIAGNOSIS .68 6.3.1
NEUTRALISING PEROXIDASE-LINKED ANTIBODY TEST .69 6.3.2 INDIRECT ELISA
.69 6.4 SERO-RESPONSE TO VACCINATION .70 6.4.1 INACTIVATED CDV VACCINE
.70 6.4.2 CDV-ISCOM VACCINE .71 6.4.3 MODIFIED LIVE VIRUS VACCINE. .73
6.5 COMPARISON OF ELISA AND VIRUS NEUTRALISATION TEST. .74 6. CONTENTS
7. CONCLUSION 79 8. SUMMARY 81 9. ZUSAMMENFASSUNG .83 10. REFERENCES.
.85 11. APPENDIX 108 APPENDIX 1 108 APPENDIX II 109 APPENDIX III. 112
LIST OF TABLES 115 LIST OF FIGURES. 117 PUBLICATIONS 118
ACKNOWLEDGEMENTS. 119 SELBSTAENDIGKEITSERKLAERUNG 122
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| any_adam_object | 1 |
| author | Günther-Weigl, Astrid Martha |
| author_GND | (DE-588)140771646 |
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| building | Verbundindex |
| bvnumber | BV036118259 |
| classification_rvk | XD 3304 |
| ctrlnum | (OCoLC)591654301 (DE-599)DNB1000789950 |
| dewey-full | 571.964619769 630 |
| dewey-hundreds | 500 - Natural sciences and mathematics 600 - Technology (Applied sciences) |
| dewey-ones | 571 - Physiology & related subjects 630 - Agriculture and related technologies |
| dewey-raw | 571.964619769 630 |
| dewey-search | 571.964619769 630 |
| dewey-sort | 3571.964619769 |
| dewey-tens | 570 - Biology 630 - Agriculture and related technologies |
| discipline | Biologie Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau Medizin |
| edition | 1. Aufl. |
| format | Thesis Book |
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| isbn | 9783941703568 |
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| physical | 122 S. Ill., graph. Darst., Kt. 21 cm |
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| spelling | Günther-Weigl, Astrid Martha Verfasser (DE-588)140771646 aut Humorale Immunantwort bei Europäischen Fischottern (Lutra lutra), Asiatischen Kurzkrallenottern (Aonyx cinereus) und Nordamerikanischen Fischottern (Lontra canadensis) nach Impfung mit unterschiedlichen Staupe Impfstoffen ger Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines von Astrid Martha Günther-Weigl 1. Aufl. Gießen DVG 2009 122 S. Ill., graph. Darst., Kt. 21 cm txt rdacontent n rdamedia nc rdacarrier Zugl.: Berlin, Freie Univ., Diss., 2009 Aonyx cinereus cabt canine distemper virus cabt immune response cabt Lontra canadensis cabt Lutra lutra cabt otters cabt vaccination cabt (DE-588)4113937-9 Hochschulschrift gnd-content DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019008304&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Günther-Weigl, Astrid Martha Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines Aonyx cinereus cabt canine distemper virus cabt immune response cabt Lontra canadensis cabt Lutra lutra cabt otters cabt vaccination cabt |
| subject_GND | (DE-588)4113937-9 |
| title | Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines |
| title_auth | Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines |
| title_exact_search | Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines |
| title_full | Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines von Astrid Martha Günther-Weigl |
| title_fullStr | Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines von Astrid Martha Günther-Weigl |
| title_full_unstemmed | Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines von Astrid Martha Günther-Weigl |
| title_short | Humoral immune response in Eurasian otters (Lutra lutra), Asian small-clawed otters (Aonyx cinereus) and North American river otters (Lontra canadensis) after vaccination with different canine distemper virus vaccines |
| title_sort | humoral immune response in eurasian otters lutra lutra asian small clawed otters aonyx cinereus and north american river otters lontra canadensis after vaccination with different canine distemper virus vaccines |
| topic | Aonyx cinereus cabt canine distemper virus cabt immune response cabt Lontra canadensis cabt Lutra lutra cabt otters cabt vaccination cabt |
| topic_facet | Aonyx cinereus canine distemper virus immune response Lontra canadensis Lutra lutra otters vaccination Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019008304&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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