Vitamin E-bonded membrane: a further step in dialysis optimization
In recent years, major concerns have been expressed about long-term derangements in hemodialysis patients and possible clinically relevant blood-membrane interactions. Preliminary studies employing biocompatible membranes and antioxidant agents such as vitamin E have demonstrated significant improve...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
Karger
1999
|
| Schriftenreihe: | Contributions to nephrology
Vol. 127 |
| Schlagworte: | |
| Online-Zugang: | BFB01 BSB01 BTW01 EUV01 FAN01 FAW01 FFW01 FHI01 FHM01 FHN01 FHR01 FKE01 FNU01 FWS01 FWS02 GEM01 LCO01 SAB01 SAM01 SBG01 SBR01 SND01 TUM01 UBA01 UBG01 UBM01 UBR01 UBT01 UBW01 UER01 UPA01 Volltext |
| Zusammenfassung: | In recent years, major concerns have been expressed about long-term derangements in hemodialysis patients and possible clinically relevant blood-membrane interactions. Preliminary studies employing biocompatible membranes and antioxidant agents such as vitamin E have demonstrated significant improvements in patient organ function and hemopoietic capacity with increased hematocrit and quality of life. Using a new technology, vitamin E has now been successfully bound to the inner surface of a hollow-fiber membrane, so that the patient’s blood is flowing in contact with a layer of antioxidant agent covering the inner surface of the membrane in the hemodialyzer.The opening chapters of this publication give an overview on oxidant stress and the role of vitamin E as antioxidant agent and elaborate on technical aspects, hydraulics and permeability characteristics of the membrane in question. The main part is dedicated to the hemocompatibility of the membrane, its effect on erythrocyte morphology and survival and the impact on white cell and platelet function. The metabolic effects and the antioxidant impact of the vitamin E-coated membrane are presented in the last part of the book.Intended as a reference tool for professionals, students and fellows involved in the care of end-stage renal disease patients, it is also hoped that this book serves as a starting point for further speculations and research in the field |
| Beschreibung: | 1 Online-Ressource (X, 278 Seiten) Illustrationen, Diagramme |
| ISBN: | 9783318004540 |
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| 520 | |a In recent years, major concerns have been expressed about long-term derangements in hemodialysis patients and possible clinically relevant blood-membrane interactions. Preliminary studies employing biocompatible membranes and antioxidant agents such as vitamin E have demonstrated significant improvements in patient organ function and hemopoietic capacity with increased hematocrit and quality of life. Using a new technology, vitamin E has now been successfully bound to the inner surface of a hollow-fiber membrane, so that the patient’s blood is flowing in contact with a layer of antioxidant agent covering the inner surface of the membrane in the hemodialyzer.The opening chapters of this publication give an overview on oxidant stress and the role of vitamin E as antioxidant agent and elaborate on technical aspects, hydraulics and permeability characteristics of the membrane in question. The main part is dedicated to the hemocompatibility of the membrane, its effect on erythrocyte morphology and survival and the impact on white cell and platelet function. The metabolic effects and the antioxidant impact of the vitamin E-coated membrane are presented in the last part of the book.Intended as a reference tool for professionals, students and fellows involved in the care of end-stage renal disease patients, it is also hoped that this book serves as a starting point for further speculations and research in the field | ||
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Datensatz im Suchindex
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV036069429 |
| illustrated | Not Illustrated |
| indexdate | 2024-08-01T11:41:42Z |
| institution | BVB |
| isbn | 9783318004540 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018960733 |
| oclc_num | 873640450 |
| open_access_boolean | |
| owner | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-578 DE-1046 DE-11 |
| owner_facet | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-578 DE-1046 DE-11 |
| physical | 1 Online-Ressource (X, 278 Seiten) Illustrationen, Diagramme |
| psigel | ZDB-1-KEB |
| publishDate | 1999 |
| publishDateSearch | 1999 |
| publishDateSort | 1999 |
| publisher | Karger |
| record_format | marc |
| series | Contributions to nephrology |
| series2 | Contributions to nephrology |
| spellingShingle | Vitamin E-bonded membrane a further step in dialysis optimization Contributions to nephrology Nephrology Medical Engineering Cell Biology Oxidativer Stress (DE-588)4353497-1 gnd Antioxidans (DE-588)4142729-4 gnd Membran (DE-588)4038571-1 gnd Vitamin-E-Gruppe (DE-588)4063641-0 gnd Beschichtung (DE-588)4144863-7 gnd Hämodialyse (DE-588)4022808-3 gnd Vitamin E (DE-588)4188447-4 gnd |
| subject_GND | (DE-588)4353497-1 (DE-588)4142729-4 (DE-588)4038571-1 (DE-588)4063641-0 (DE-588)4144863-7 (DE-588)4022808-3 (DE-588)4188447-4 (DE-588)4143413-4 |
| title | Vitamin E-bonded membrane a further step in dialysis optimization |
| title_auth | Vitamin E-bonded membrane a further step in dialysis optimization |
| title_exact_search | Vitamin E-bonded membrane a further step in dialysis optimization |
| title_full | Vitamin E-bonded membrane a further step in dialysis optimization volume editors: C. Ronco, G. La Greca |
| title_fullStr | Vitamin E-bonded membrane a further step in dialysis optimization volume editors: C. Ronco, G. La Greca |
| title_full_unstemmed | Vitamin E-bonded membrane a further step in dialysis optimization volume editors: C. Ronco, G. La Greca |
| title_short | Vitamin E-bonded membrane |
| title_sort | vitamin e bonded membrane a further step in dialysis optimization |
| title_sub | a further step in dialysis optimization |
| topic | Nephrology Medical Engineering Cell Biology Oxidativer Stress (DE-588)4353497-1 gnd Antioxidans (DE-588)4142729-4 gnd Membran (DE-588)4038571-1 gnd Vitamin-E-Gruppe (DE-588)4063641-0 gnd Beschichtung (DE-588)4144863-7 gnd Hämodialyse (DE-588)4022808-3 gnd Vitamin E (DE-588)4188447-4 gnd |
| topic_facet | Nephrology Medical Engineering Cell Biology Oxidativer Stress Antioxidans Membran Vitamin-E-Gruppe Beschichtung Hämodialyse Vitamin E Aufsatzsammlung |
| url | https://karger.com/books/book/3 |
| volume_link | (DE-604)BV039142755 |
| work_keys_str_mv | AT roncoclaudio vitaminebondedmembraneafurtherstepindialysisoptimization AT grecagiuseppela vitaminebondedmembraneafurtherstepindialysisoptimization |