Vitamin E-bonded membrane a further step in dialysis optimization
Vitamin E-bonded membrane: a further step in dialysis optimization

In recent years, major concerns have been expressed about long-term derangements in hemodialysis patients and possible clinically relevant blood-membrane interactions. Preliminary studies employing biocompatible membranes and antioxidant agents such as vitamin E have demonstrated significant improve...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Weitere Verfasser: Ronco, Claudio 1951- (HerausgeberIn), Greca, Giuseppe la (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Basel Karger 1999
Schriftenreihe:Contributions to nephrology Vol. 127
Schlagworte:
Nephrology
Medical Engineering
Cell Biology
Beschichtung
Antioxidans
Vitamin E
Hämodialyse
Membran
Vitamin-E-Gruppe
Oxidativer Stress
Aufsatzsammlung
Online-Zugang:DE-522
DE-12
DE-526
DE-521
DE-1102
DE-1046
DE-1028
DE-573
DE-M347
DE-92
DE-898
DE-859
DE-1049
DE-863
DE-862
DE-M382
DE-70
DE-128
DE-54
DE-22
DE-155
DE-150
DE-91
DE-384
DE-473
DE-19
DE-355
DE-703
DE-20
DE-706
DE-29
DE-739
Volltext
Zusammenfassung:In recent years, major concerns have been expressed about long-term derangements in hemodialysis patients and possible clinically relevant blood-membrane interactions. Preliminary studies employing biocompatible membranes and antioxidant agents such as vitamin E have demonstrated significant improvements in patient organ function and hemopoietic capacity with increased hematocrit and quality of life. Using a new technology, vitamin E has now been successfully bound to the inner surface of a hollow-fiber membrane, so that the patient’s blood is flowing in contact with a layer of antioxidant agent covering the inner surface of the membrane in the hemodialyzer.The opening chapters of this publication give an overview on oxidant stress and the role of vitamin E as antioxidant agent and elaborate on technical aspects, hydraulics and permeability characteristics of the membrane in question. The main part is dedicated to the hemocompatibility of the membrane, its effect on erythrocyte morphology and survival and the impact on white cell and platelet function. The metabolic effects and the antioxidant impact of the vitamin E-coated membrane are presented in the last part of the book.Intended as a reference tool for professionals, students and fellows involved in the care of end-stage renal disease patients, it is also hoped that this book serves as a starting point for further speculations and research in the field
Beschreibung:1 Online-Ressource (X, 278 Seiten) Illustrationen, Diagramme
ISBN:9783318004540
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