Verfügbarkeit: Proteomics in nephrology

Proteomics in nephrology:

The novel discipline of proteomics has experienced a rapid growth in the recent past and has a great potential for the future. Involving several fields, it offers various advantages: The study of proteins on a genomic scale allows to examine a large number of them simultaneously. Moreover, proteomic...

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Weitere Verfasser:	Thongboonkerd, Visith (HerausgeberIn), Klein, Jon B. (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Basel Karger 2004
Schriftenreihe:	Contributions to nephrology Vol. 141
Schlagworte:	Nephrology Biochemistry Biotechnology Genetics Internal Medicine Laboratory Proteomics Proteomanalyse Nierenkrankheit Aufsatzsammlung
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Zusammenfassung:	The novel discipline of proteomics has experienced a rapid growth in the recent past and has a great potential for the future. Involving several fields, it offers various advantages: The study of proteins on a genomic scale allows to examine a large number of them simultaneously. Moreover, proteomic analysis provides information about post-translational modifications and functions of gene products or proteins that cannot be obtained by genomic analysis. The knowledge thus gained is also important for a better understanding of renal physiology and pathophysiology, to identify disease biomarkers, and to develop new target therapies.This book is the first one that applies the science of proteomics to nephrology: It sets out to give an overview of the discipline, providing detailed background information and outlining scope, advantages, and limitations of proteomics.The second section reviews principles of commonly used proteomic techniques, including sample preparation, two-dimensional gel electrophoresis, various types of mass spectrometry, expression proteomics, quantitative proteomics, practical bioinformatics, and clinical proteomics. In the last section, examples and perspectives are provided of how proteomics can be applied to various fields in nephrology, including nephrotoxicity, sodium transport, diabetic nephropathy, renal Fanconi syndrome, IgA nephropathy, physiology of podocytes and mesangial cells, hypertension, urological malignancies, and dialysis. The publication ends with a discussion of biomarker discovery in glomerular diseases and drug discovery.Written by acclaimed experts in both proteomics and nephrology, this truly remarkable book is essential reading for students, residents, fellows, scientists, and nephrologists who are interested in or devoted to research, as well as for general health professionals and clinicians
Beschreibung:	an introduction to a coming field of science
Beschreibung:	1 Online-Ressource (VIII, 336 Seiten) Illustrationen, Diagramme
ISBN:	9783318010145

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genre	(DE-588)4143413-4 Aufsatzsammlung gnd-content
genre_facet	Aufsatzsammlung
id	DE-604.BV036069360
illustrated	Not Illustrated
indexdate	2024-08-01T11:41:42Z
institution	BVB
isbn	9783318010145
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-018960665
oclc_num	837657239
open_access_boolean
owner	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-578 DE-11 DE-1046
owner_facet	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-578 DE-11 DE-1046
physical	1 Online-Ressource (VIII, 336 Seiten) Illustrationen, Diagramme
psigel	ZDB-1-KEB
publishDate	2004
publishDateSearch	2004
publishDateSort	2004
publisher	Karger
record_format	marc
series	Contributions to nephrology
series2	Contributions to nephrology
spellingShingle	Proteomics in nephrology Contributions to nephrology Nephrology Biochemistry Biotechnology Genetics Internal Medicine Laboratory Proteomics Proteomanalyse (DE-588)4596545-6 gnd Nierenkrankheit (DE-588)4075399-2 gnd
subject_GND	(DE-588)4596545-6 (DE-588)4075399-2 (DE-588)4143413-4
title	Proteomics in nephrology
title_auth	Proteomics in nephrology
title_exact_search	Proteomics in nephrology
title_full	Proteomics in nephrology volume editors: Visith Thongboonkerd, Jon B. Klein
title_fullStr	Proteomics in nephrology volume editors: Visith Thongboonkerd, Jon B. Klein
title_full_unstemmed	Proteomics in nephrology volume editors: Visith Thongboonkerd, Jon B. Klein
title_short	Proteomics in nephrology
title_sort	proteomics in nephrology
topic	Nephrology Biochemistry Biotechnology Genetics Internal Medicine Laboratory Proteomics Proteomanalyse (DE-588)4596545-6 gnd Nierenkrankheit (DE-588)4075399-2 gnd
topic_facet	Nephrology Biochemistry Biotechnology Genetics Internal Medicine Laboratory Proteomics Proteomanalyse Nierenkrankheit Aufsatzsammlung
url	https://karger.com/books/book/2464
volume_link	(DE-604)BV039142755
work_keys_str_mv	AT thongboonkerdvisith proteomicsinnephrology AT kleinjonb proteomicsinnephrology

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