Prader-Willi syndrome: effects of human growth hormone treatment
Over the past years, great advances have been made in the research of Prader-Willi Syndrome and its treatment options. The results raise hopes that the once depressing outlook for children with PWS and their parents will gradually give way to a much improved quality of life.Clinical research has sho...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
Karger
2001
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| Schriftenreihe: | Endocrine development
Vol. 3 |
| Schlagworte: | |
| Online-Zugang: | BFB01 BSB01 BTW01 EUV01 FAN01 FAW01 FFW01 FHI01 FHM01 FHN01 FHR01 FKE01 FNU01 FWS01 FWS02 GEM01 LCO01 SAB01 SAM01 SBG01 SBR01 SND01 TUM01 UBA01 UBG01 UBM01 UBR01 UBT01 UBW01 UER01 UPA01 Volltext |
| Zusammenfassung: | Over the past years, great advances have been made in the research of Prader-Willi Syndrome and its treatment options. The results raise hopes that the once depressing outlook for children with PWS and their parents will gradually give way to a much improved quality of life.Clinical research has shown that there is a hypothalamic growth hormone deficiency in PWS and that growth hormone treatment improves body composition, body proportions and physical performance of patients. Increased lean body mass enhances energy expenditure and – provided the energy input can be restrained – children no longer become obese. The disappearance of the obese phenotype in children with PWS who are treated with growth hormone starting before puberty prevents stigmatisation of children and their families in society. The mental retardation and the compulsive behavior disorder will however remain major handicaps which seemingly cannot be influenced by growth hormone therapy.This book provides an overview of the clinical research results as to hormones and metabolism of PWS with special emphasis on growth hormone and growth hormone treatment. Besides the outstanding scientific texts, this volume offers comprehensive photographic material to document the development of selected patients over several years and to illustrate extreme individual changes in the physical appearance and facial expression |
| Beschreibung: | 1 Online-Ressource (XII, 118 Seiten) Illustrationen, Diagramme |
| ISBN: | 9783318007312 |
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| 520 | |a Over the past years, great advances have been made in the research of Prader-Willi Syndrome and its treatment options. The results raise hopes that the once depressing outlook for children with PWS and their parents will gradually give way to a much improved quality of life.Clinical research has shown that there is a hypothalamic growth hormone deficiency in PWS and that growth hormone treatment improves body composition, body proportions and physical performance of patients. Increased lean body mass enhances energy expenditure and – provided the energy input can be restrained – children no longer become obese. The disappearance of the obese phenotype in children with PWS who are treated with growth hormone starting before puberty prevents stigmatisation of children and their families in society. The mental retardation and the compulsive behavior disorder will however remain major handicaps which seemingly cannot be influenced by growth hormone therapy.This book provides an overview of the clinical research results as to hormones and metabolism of PWS with special emphasis on growth hormone and growth hormone treatment. Besides the outstanding scientific texts, this volume offers comprehensive photographic material to document the development of selected patients over several years and to illustrate extreme individual changes in the physical appearance and facial expression | ||
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Datensatz im Suchindex
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| id | DE-604.BV036069345 |
| illustrated | Not Illustrated |
| indexdate | 2024-08-01T11:41:42Z |
| institution | BVB |
| isbn | 9783318007312 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018960650 |
| oclc_num | 729848124 |
| open_access_boolean | |
| owner | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 |
| owner_facet | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 |
| physical | 1 Online-Ressource (XII, 118 Seiten) Illustrationen, Diagramme |
| psigel | ZDB-1-KEB |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Karger |
| record_format | marc |
| series | Endocrine development |
| series2 | Endocrine development |
| spellingShingle | Eiholzer, Urs 1951- Prader-Willi syndrome effects of human growth hormone treatment Endocrine development Endocrinology Pediatrics Human Genetics Metabolism Nutrition Pediatric Endocrinology Somatotropin (DE-588)4137446-0 gnd Prader-Willi-Syndrom (DE-588)4201277-6 gnd |
| subject_GND | (DE-588)4137446-0 (DE-588)4201277-6 |
| title | Prader-Willi syndrome effects of human growth hormone treatment |
| title_auth | Prader-Willi syndrome effects of human growth hormone treatment |
| title_exact_search | Prader-Willi syndrome effects of human growth hormone treatment |
| title_full | Prader-Willi syndrome effects of human growth hormone treatment Urs Eiholzer |
| title_fullStr | Prader-Willi syndrome effects of human growth hormone treatment Urs Eiholzer |
| title_full_unstemmed | Prader-Willi syndrome effects of human growth hormone treatment Urs Eiholzer |
| title_short | Prader-Willi syndrome |
| title_sort | prader willi syndrome effects of human growth hormone treatment |
| title_sub | effects of human growth hormone treatment |
| topic | Endocrinology Pediatrics Human Genetics Metabolism Nutrition Pediatric Endocrinology Somatotropin (DE-588)4137446-0 gnd Prader-Willi-Syndrom (DE-588)4201277-6 gnd |
| topic_facet | Endocrinology Pediatrics Human Genetics Metabolism Nutrition Pediatric Endocrinology Somatotropin Prader-Willi-Syndrom |
| url | https://karger.com/books/book/2389 |
| volume_link | (DE-604)BV039142747 |
| work_keys_str_mv | AT eiholzerurs praderwillisyndromeeffectsofhumangrowthhormonetreatment |