Molecular pathogenesis of MODYs:
A timely collection of research papers by 18 leading scientists in the area of biochemical genetics of diabetes mellitus, these contributions focus on a well defined class of monogenic forms of the disease (i.e. MODYs 1–5) all caused by specific mutations or deletion of genes that control pancreatic...
Gespeichert in:
Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Basel
Karger
2000
|
Schriftenreihe: | Frontiers in diabetes
Vol. 15 |
Schlagworte: | |
Online-Zugang: | BFB01 BSB01 BTW01 EUV01 FAN01 FAW01 FFW01 FHI01 FHM01 FHN01 FHR01 FKE01 FNU01 FWS01 FWS02 GEM01 LCO01 SAB01 SAM01 SBG01 SBR01 SND01 TUM01 UBA01 UBG01 UBM01 UBR01 UBT01 UBW01 UER01 UPA01 Volltext |
Zusammenfassung: | A timely collection of research papers by 18 leading scientists in the area of biochemical genetics of diabetes mellitus, these contributions focus on a well defined class of monogenic forms of the disease (i.e. MODYs 1–5) all caused by specific mutations or deletion of genes that control pancreatic beta-cell functions: HNF-4alpha (1), glucokinase (2), HNF-1alpha (3), IDX-1 (4) and HNF-1beta (5).This volume offers a historical perspective of MODYs, and it also contains contributions which deal with the fundamental questions of pancreas and liver development, critical for the understanding of the syndrome complex discussed. Attempts have been made to highlight results and concepts that may be relevant for understanding type-II diabetes in general, exemplified by contributions that connect the field of pancreatic islet cell biology and pathology with the newest findings in the area of insulin action, e.g. the role of the insulin receptor and insulin receptor substrates (IRS 1–3). Covering a broad and novel approach on the subject of MODYs, this book looks into the future of molecular genetic and biochemical research in this area. It is recommended reading for basic research scientists in the area of diabetes mellitus, academically oriented endocrinologists and clinical researchers |
Beschreibung: | 1 Online-Ressource (X, 271 Seiten) Illustrationen, Diagramme |
ISBN: | 9783318004915 |
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490 | 1 | |a Frontiers in diabetes |v Vol. 15 | |
520 | |a A timely collection of research papers by 18 leading scientists in the area of biochemical genetics of diabetes mellitus, these contributions focus on a well defined class of monogenic forms of the disease (i.e. MODYs 1–5) all caused by specific mutations or deletion of genes that control pancreatic beta-cell functions: HNF-4alpha (1), glucokinase (2), HNF-1alpha (3), IDX-1 (4) and HNF-1beta (5).This volume offers a historical perspective of MODYs, and it also contains contributions which deal with the fundamental questions of pancreas and liver development, critical for the understanding of the syndrome complex discussed. Attempts have been made to highlight results and concepts that may be relevant for understanding type-II diabetes in general, exemplified by contributions that connect the field of pancreatic islet cell biology and pathology with the newest findings in the area of insulin action, e.g. the role of the insulin receptor and insulin receptor substrates (IRS 1–3). Covering a broad and novel approach on the subject of MODYs, this book looks into the future of molecular genetic and biochemical research in this area. It is recommended reading for basic research scientists in the area of diabetes mellitus, academically oriented endocrinologists and clinical researchers | ||
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Datensatz im Suchindex
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genre | (DE-588)1071861417 Konferenzschrift 1998 Scottsdale Ariz. gnd-content |
genre_facet | Konferenzschrift 1998 Scottsdale Ariz. |
id | DE-604.BV036069253 |
illustrated | Not Illustrated |
indexdate | 2024-08-01T11:41:42Z |
institution | BVB |
isbn | 9783318004915 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018960557 |
oclc_num | 728412300 |
open_access_boolean | |
owner | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 |
owner_facet | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 |
physical | 1 Online-Ressource (X, 271 Seiten) Illustrationen, Diagramme |
psigel | ZDB-1-KEB |
publishDate | 2000 |
publishDateSearch | 2000 |
publishDateSort | 2000 |
publisher | Karger |
record_format | marc |
series | Frontiers in diabetes |
series2 | Frontiers in diabetes |
spellingShingle | Molecular pathogenesis of MODYs Frontiers in diabetes Endocrinology Biochemistry Diabetes Embryology Enzymology Human Genetics Metabolic Diseases Pathogenese (DE-588)4115512-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Diabetes mellitus (DE-588)4070446-4 gnd |
subject_GND | (DE-588)4115512-9 (DE-588)4039983-7 (DE-588)4070446-4 (DE-588)1071861417 |
title | Molecular pathogenesis of MODYs |
title_auth | Molecular pathogenesis of MODYs |
title_exact_search | Molecular pathogenesis of MODYs |
title_full | Molecular pathogenesis of MODYs volume editors: F. M. Matschinsky, M. A. Magnuson |
title_fullStr | Molecular pathogenesis of MODYs volume editors: F. M. Matschinsky, M. A. Magnuson |
title_full_unstemmed | Molecular pathogenesis of MODYs volume editors: F. M. Matschinsky, M. A. Magnuson |
title_short | Molecular pathogenesis of MODYs |
title_sort | molecular pathogenesis of modys |
topic | Endocrinology Biochemistry Diabetes Embryology Enzymology Human Genetics Metabolic Diseases Pathogenese (DE-588)4115512-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Diabetes mellitus (DE-588)4070446-4 gnd |
topic_facet | Endocrinology Biochemistry Diabetes Embryology Enzymology Human Genetics Metabolic Diseases Pathogenese Molekularbiologie Diabetes mellitus Konferenzschrift 1998 Scottsdale Ariz. |
url | https://karger.com/books/book/2344 |
volume_link | (DE-604)BV039142753 |
work_keys_str_mv | AT matschinskyfranz molecularpathogenesisofmodys AT magnusonmarka molecularpathogenesisofmodys |