Verfügbarkeit: Ischemic stroke

Ischemic stroke: from basic mechanisms to new drug development

Stroke is the third leading cause of death in industrialized countries and the number one cause of disability in adults. Ischemic strokes constitute approximately 80% of all strokes, and until recently, no effective therapies had been available. The successful tissue plasminogen activator (tPA) tria...

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Weitere Verfasser:	Hsu, Chung Y. (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Basel Karger 1998
Schriftenreihe:	Monographs in clinical neuroscience Vol. 16
Schlagworte:	Neurology Cardiovascular System Neurosurgery Pharmacokinetics Pharmacology Traumatology Ischämie Hirnkrankheit Schlaganfall Aufsatzsammlung
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Zusammenfassung:	Stroke is the third leading cause of death in industrialized countries and the number one cause of disability in adults. Ischemic strokes constitute approximately 80% of all strokes, and until recently, no effective therapies had been available. The successful tissue plasminogen activator (tPA) trials open a new era of stroke management with a proven therapeutic now available to patients if they arrive at the hospital within hours of the onset of symptoms. Recent advances in our understanding of the molecular mechanisms of ischemic brain injury and vascular pathology have opened up new avenues for the development of novel therapeutic strategies. The premise that substantial reduction of brain damage after ischemic stroke by therapeutic intervention has now been confirmed in animal stroke models, sets a realistic goal for future treatment of stroke patients. This book covers topics ranging from fundamental molecular mechanisms of ischemic brain injury to the most current views on the clinical stroke trials and academic and industrial efforts to develop new drugs.The authors are leading authorities in their own fields in basic and clinical stroke research. As a timely and comprehensive volume, it will be of immense value to basic and clinical investigators, neurologists and neurosurgeons who manage stroke patients, neuroscientists interested in various aspects of brain injury, and researchers in the pharmaceutical industry who are engaged in new drug development
Beschreibung:	1 Online-Ressource (IX, 166 Seiten) Illustrationen, Diagramme
ISBN:	9783318002553

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genre	(DE-588)4143413-4 Aufsatzsammlung gnd-content
genre_facet	Aufsatzsammlung
id	DE-604.BV036069211
illustrated	Not Illustrated
indexdate	2024-08-01T11:41:42Z
institution	BVB
isbn	9783318002553
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-018960516
oclc_num	728414705
open_access_boolean
owner	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-1046 DE-11 DE-578
owner_facet	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-83 DE-M382 DE-70 DE-1046 DE-11 DE-578
physical	1 Online-Ressource (IX, 166 Seiten) Illustrationen, Diagramme
psigel	ZDB-1-KEB
publishDate	1998
publishDateSearch	1998
publishDateSort	1998
publisher	Karger
record_format	marc
series	Monographs in clinical neuroscience
series2	Monographs in clinical neuroscience
spellingShingle	Ischemic stroke from basic mechanisms to new drug development Monographs in clinical neuroscience Neurology Cardiovascular System Neurosurgery Pharmacokinetics Pharmacology Traumatology Ischämie (DE-588)4162456-7 gnd Hirnkrankheit (DE-588)4025013-1 gnd Schlaganfall (DE-588)4052588-0 gnd
subject_GND	(DE-588)4162456-7 (DE-588)4025013-1 (DE-588)4052588-0 (DE-588)4143413-4
title	Ischemic stroke from basic mechanisms to new drug development
title_auth	Ischemic stroke from basic mechanisms to new drug development
title_exact_search	Ischemic stroke from basic mechanisms to new drug development
title_full	Ischemic stroke from basic mechanisms to new drug development volume editor: Chung Y. Hsu
title_fullStr	Ischemic stroke from basic mechanisms to new drug development volume editor: Chung Y. Hsu
title_full_unstemmed	Ischemic stroke from basic mechanisms to new drug development volume editor: Chung Y. Hsu
title_short	Ischemic stroke
title_sort	ischemic stroke from basic mechanisms to new drug development
title_sub	from basic mechanisms to new drug development
topic	Neurology Cardiovascular System Neurosurgery Pharmacokinetics Pharmacology Traumatology Ischämie (DE-588)4162456-7 gnd Hirnkrankheit (DE-588)4025013-1 gnd Schlaganfall (DE-588)4052588-0 gnd
topic_facet	Neurology Cardiovascular System Neurosurgery Pharmacokinetics Pharmacology Traumatology Ischämie Hirnkrankheit Schlaganfall Aufsatzsammlung
url	https://karger.com/books/book/2288
volume_link	(DE-604)BV044490763
work_keys_str_mv	AT hsuchungy ischemicstrokefrombasicmechanismstonewdrugdevelopment

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