Hypothalamic-pituitary development genetic and clinical aspects
Hypothalamic-pituitary development: genetic and clinical aspects

In recent years dramatic progress has been made in understanding the pathophysiology of pituitary diseases by a combination of experimental studies, molecular genetics and clinical research. This book presents an updated overview of normal and pathological hypothalamic-pituitary development. Several...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Weitere Verfasser: Rappaport, Raphaël (HerausgeberIn), Amselem, Serge (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Basel Karger 2001
Schriftenreihe:Endocrine development Vol. 4
Schlagworte:
Endocrinology
Pediatrics
Genetics
Molecular Biology
Pediatric Endocrinology
Hypophysen-Zwischenhirn-System
Entwicklung
Hypophyse
Hypothalamus
Neuroendokrines System
Hypophysenkrankheit
Aufsatzsammlung
Online-Zugang:DE-522
DE-12
DE-526
DE-521
DE-1102
DE-1046
DE-1028
DE-573
DE-M347
DE-92
DE-898
DE-859
DE-1049
DE-863
DE-862
DE-M382
DE-70
DE-128
DE-54
DE-22
DE-155
DE-150
DE-91
DE-384
DE-473
DE-19
DE-355
DE-703
DE-20
DE-706
DE-29
DE-739
Volltext
Zusammenfassung:In recent years dramatic progress has been made in understanding the pathophysiology of pituitary diseases by a combination of experimental studies, molecular genetics and clinical research. This book presents an updated overview of normal and pathological hypothalamic-pituitary development. Several chapters include experimental data and describe brain and facial defects associated with various conditions of pituitary insufficiency. A major part is devoted to the still increasing number of molecular and genetic defects which are responsible for various clinical presentations of pituitary insufficiency: diseases due to genetic defects of growth hormone, TSH, gonadotropins and corticotropin secretion are extensively described. These diseases present as metabolic (diabetes insipidus and adrenal insufficiency), growth and reproductive (including puberty) disorders. A distinct chapter emphasizes the contribution of a multidisciplinary comprehensive approach including the most recent molecular and genetic tools. Finally in most chapters an effort was made to address phenotypic and genotypic presentations in affected patients including valuable information provided by magnetic resonance imaging of the pituitary and brain.This book will help endocrinologists and pediatricians by providing unique models of genetic and developmental defects of the pituitary region which bear ultimate consequences on metabolic control, growth and reproduction
Beschreibung:1 Online-Ressource (X, 180 Seiten) Illustrationen, Diagramme
ISBN:9783318007145
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