Verfügbarkeit: Humoral immunity in kidney transplantation

Humoral immunity in kidney transplantation: what clinicians need to know

As recent advances in immunosuppression and apheresis techniques have opened new avenues for the management of humoral immunity, interest in ABO-incompatible kidney transplantation has been renewed. Moreover, new screening techniques – such as the single antigen bead assay – allow for the detection...

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Weitere Verfasser:	Remuzzi, Giuseppe 1949- (HerausgeberIn), Chiaramonte, Stefano (HerausgeberIn), Perico, Norberto (HerausgeberIn), Ronco, Claudio 1951- (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Basel Karger 2009
Schriftenreihe:	Contributions to nephrology Vol. 162
Schlagworte:	Nephrology Immunology Pharmacology Transplantation Nierentransplantation Immunologie Aufsatzsammlung
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Zusammenfassung:	As recent advances in immunosuppression and apheresis techniques have opened new avenues for the management of humoral immunity, interest in ABO-incompatible kidney transplantation has been renewed. Moreover, new screening techniques – such as the single antigen bead assay – allow for the detection and definition of very low levels of alloantibody, which has had a positive impact on the treatment possibilities in highly sensitized adult patients with end-stage renal disease. But despite these advances, a theoretical rationale is still missing for both the decision to transplant a sensitized patient and the classification of the transplant as low, medium or high risk. There is also no uniform approach with regard to pre-transplant desensitization protocols, and it is unclear whether particular post-transplant immunosuppression will be required and what would be the best combination treatment. Last but not least, the frequency and actual clinical impact of alloantibodies developed after transplantation on short- and long-term graft survival need to be ascertained.Aimed especially at the clinician, this publication presents recent insights in the characterization and pathogenetic role of humoral immunity in chronic allograft injury and investigates the perspectives for novel immunosuppressive therapies to control antibody production after transplantation
Beschreibung:	1 Online-Ressource (IX, 145 Seiten) Illustrationen
ISBN:	9783805589598

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genre	(DE-588)4143413-4 Aufsatzsammlung gnd-content
genre_facet	Aufsatzsammlung
id	DE-604.BV036069185
illustrated	Not Illustrated
indexdate	2024-08-01T11:41:42Z
institution	BVB
isbn	9783805589598
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-018960488
oclc_num	837654396
open_access_boolean
owner	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
owner_facet	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
physical	1 Online-Ressource (IX, 145 Seiten) Illustrationen
psigel	ZDB-1-KEB
publishDate	2009
publishDateSearch	2009
publishDateSort	2009
publisher	Karger
record_format	marc
series	Contributions to nephrology
series2	Contributions to nephrology
spellingShingle	Humoral immunity in kidney transplantation what clinicians need to know Contributions to nephrology Nephrology Immunology Pharmacology Transplantation Nierentransplantation (DE-588)4042284-7 gnd Immunologie (DE-588)4026637-0 gnd
subject_GND	(DE-588)4042284-7 (DE-588)4026637-0 (DE-588)4143413-4
title	Humoral immunity in kidney transplantation what clinicians need to know
title_auth	Humoral immunity in kidney transplantation what clinicians need to know
title_exact_search	Humoral immunity in kidney transplantation what clinicians need to know
title_full	Humoral immunity in kidney transplantation what clinicians need to know volume editors: Giuseppe Remuzzi, Stefano Chiaramonte, Norberto Perico, Claudio Ronco
title_fullStr	Humoral immunity in kidney transplantation what clinicians need to know volume editors: Giuseppe Remuzzi, Stefano Chiaramonte, Norberto Perico, Claudio Ronco
title_full_unstemmed	Humoral immunity in kidney transplantation what clinicians need to know volume editors: Giuseppe Remuzzi, Stefano Chiaramonte, Norberto Perico, Claudio Ronco
title_short	Humoral immunity in kidney transplantation
title_sort	humoral immunity in kidney transplantation what clinicians need to know
title_sub	what clinicians need to know
topic	Nephrology Immunology Pharmacology Transplantation Nierentransplantation (DE-588)4042284-7 gnd Immunologie (DE-588)4026637-0 gnd
topic_facet	Nephrology Immunology Pharmacology Transplantation Nierentransplantation Immunologie Aufsatzsammlung
url	https://karger.com/books/book/2636
volume_link	(DE-604)BV039142755
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