Heart rate slowing by /f current inhibition:
This book unfolds the history of the discovery of the transmembrane channel which is responsible for the ‘funny’ or /f current, the primary modulator of heart rate. Inhibition of this current leads to slowing of the heart rate, which is an important component of the successful management of angina p...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
Karger
2006
|
| Schriftenreihe: | Advances in cardiology
Vol. 43 |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Zusammenfassung: | This book unfolds the history of the discovery of the transmembrane channel which is responsible for the ‘funny’ or /f current, the primary modulator of heart rate. Inhibition of this current leads to slowing of the heart rate, which is an important component of the successful management of angina pectoris. Recently, Ivabradine, a specific and selective inhibitor of the /f current, has been developed as an antianginal agent which has been shown to be at least as effective as both beta-blockers and calcium channel blockers for the treatment of angina. The development, efficacy and complications of this therapy are discussed in detail in this book. Furthermore, the clinical benefits from heart rate reduction in patients with coronary artery disease and heart failure and in patients after myocardial infarction are examined. Whether a lower heart rate per se will prolong life is not yet known, but it may offer a new and important life-saving strategy.The current data presented in this volume will be appreciated by cardiologists and general physicians interested in the modern management of angina pectoris and by electrophysiologists and physiologists who would like to understand the importance of heart rate and its regulation |
| Beschreibung: | Includes bibliographical references and indexes a new strategy for the management of angina pectoris |
| Beschreibung: | 1 Online-Ressource (VIII, 115 Seiten) Illustrationen |
| ISBN: | 9783318013818 |
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| 520 | |a This book unfolds the history of the discovery of the transmembrane channel which is responsible for the ‘funny’ or /f current, the primary modulator of heart rate. Inhibition of this current leads to slowing of the heart rate, which is an important component of the successful management of angina pectoris. Recently, Ivabradine, a specific and selective inhibitor of the /f current, has been developed as an antianginal agent which has been shown to be at least as effective as both beta-blockers and calcium channel blockers for the treatment of angina. The development, efficacy and complications of this therapy are discussed in detail in this book. Furthermore, the clinical benefits from heart rate reduction in patients with coronary artery disease and heart failure and in patients after myocardial infarction are examined. Whether a lower heart rate per se will prolong life is not yet known, but it may offer a new and important life-saving strategy.The current data presented in this volume will be appreciated by cardiologists and general physicians interested in the modern management of angina pectoris and by electrophysiologists and physiologists who would like to understand the importance of heart rate and its regulation | ||
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| id | DE-604.BV036069167 |
| illustrated | Not Illustrated |
| indexdate | 2024-08-01T11:41:30Z |
| institution | BVB |
| isbn | 9783318013818 |
| language | English |
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| physical | 1 Online-Ressource (VIII, 115 Seiten) Illustrationen |
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| publishDate | 2006 |
| publishDateSearch | 2006 |
| publishDateSort | 2006 |
| publisher | Karger |
| record_format | marc |
| series | Advances in cardiology |
| series2 | Advances in cardiology |
| spellingShingle | Heart rate slowing by /f current inhibition Advances in cardiology Cardiovascular System Electrocardiogram Pharmacology Physiology Angina pectoris (DE-588)4002029-0 gnd Herzfrequenz (DE-588)4125645-1 gnd |
| subject_GND | (DE-588)4002029-0 (DE-588)4125645-1 |
| title | Heart rate slowing by /f current inhibition |
| title_alt | Heart rate slowing by f current inhibition |
| title_auth | Heart rate slowing by /f current inhibition |
| title_exact_search | Heart rate slowing by /f current inhibition |
| title_full | Heart rate slowing by /f current inhibition volume editors: A. John Camm, Michal Tendera |
| title_fullStr | Heart rate slowing by /f current inhibition volume editors: A. John Camm, Michal Tendera |
| title_full_unstemmed | Heart rate slowing by /f current inhibition volume editors: A. John Camm, Michal Tendera |
| title_short | Heart rate slowing by /f current inhibition |
| title_sort | heart rate slowing by f current inhibition |
| topic | Cardiovascular System Electrocardiogram Pharmacology Physiology Angina pectoris (DE-588)4002029-0 gnd Herzfrequenz (DE-588)4125645-1 gnd |
| topic_facet | Cardiovascular System Electrocardiogram Pharmacology Physiology Angina pectoris Herzfrequenz |
| url | https://karger.com/books/book/2551 |
| volume_link | (DE-604)BV037287955 |
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