Verfügbarkeit: Current research in head and neck cancer

Current research in head and neck cancer: molecular pathways, novel therapeutic targets, and prognostic factors

The development of head and neck cancer is a multistep process in which genetic as well as epigenetic alterations interfere with the regular functions of proto-oncogenes and tumor suppressor genes. In addition, carcinogenesis is promoted by the impairment of mechanisms responsible for the maintenanc...

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Weitere Verfasser:	Bier, Henning 1957-2018 (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Basel Karger 2005
Schriftenreihe:	Advances in oto-rhino-laryngology Vol. 62
Schlagworte:	Otorhinolaryngology Oncology Cell Biology Immunology Molecular Biology Krebs > Medizin Kopfregion Halsregion Aufsatzsammlung
Online-Zugang:	BFB01 BSB01 BTW01 EUV01 FAN01 FAW01 FFW01 FHI01 FHM01 FHN01 FHR01 FKE01 FNU01 FWS01 FWS02 GEM01 LCO01 SAB01 SAM01 SBG01 SBR01 SND01 TUM01 UBA01 UBG01 UBM01 UBR01 UBT01 UBW01 UER01 UPA01 Volltext
Zusammenfassung:	The development of head and neck cancer is a multistep process in which genetic as well as epigenetic alterations interfere with the regular functions of proto-oncogenes and tumor suppressor genes. In addition, carcinogenesis is promoted by the impairment of mechanisms responsible for the maintenance of genetic stability. The accumulation of crucial events such as evasion of apoptosis, lack of senescence, deregulated proliferation, invasion and metastasis, as well as neoangiogenesis eventually determines the malignant phenotype. The 16 articles of this volume span from advances in the understanding of underlying molecular pathways (conditional mouse model, folate activity, DNA repair, genomic heterogeneity, p53 family members, human papillomavirus), to preclinical and clinical studies investigating potential novel therapeutic targets (epidermal growth factor receptor, nuclear factor-kappaB, vascular endothelial growth factor, chemokine receptors, P53-based immunotherapy, virus-modified tumor vaccination), and biometric considerations on the evaluation of prognostic factors.This state-of-the-art publication is recommended reading not only for ENT specialists and oncologists, but also for molecular biologists and other subspecialists interested in head and neck cancer research
Beschreibung:	new insights into basic and translational research
Beschreibung:	1 Online-Ressource (VI, 207 Seiten) Illustrationen, Diagramme
ISBN:	9783318011197

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Datensatz im Suchindex

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genre	(DE-588)4143413-4 Aufsatzsammlung gnd-content
genre_facet	Aufsatzsammlung
id	DE-604.BV036069091
illustrated	Not Illustrated
indexdate	2024-08-01T11:41:30Z
institution	BVB
isbn	9783318011197
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-018960395
oclc_num	873636673
open_access_boolean
owner	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
owner_facet	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
physical	1 Online-Ressource (VI, 207 Seiten) Illustrationen, Diagramme
psigel	ZDB-1-KEB
publishDate	2005
publishDateSearch	2005
publishDateSort	2005
publisher	Karger
record_format	marc
series	Advances in oto-rhino-laryngology
series2	Advances in oto-rhino-laryngology
spellingShingle	Current research in head and neck cancer molecular pathways, novel therapeutic targets, and prognostic factors Advances in oto-rhino-laryngology Otorhinolaryngology Oncology Cell Biology Immunology Molecular Biology Krebs Medizin (DE-588)4073781-0 gnd Kopfregion (DE-588)4132084-0 gnd Halsregion (DE-588)4113837-5 gnd
subject_GND	(DE-588)4073781-0 (DE-588)4132084-0 (DE-588)4113837-5 (DE-588)4143413-4
title	Current research in head and neck cancer molecular pathways, novel therapeutic targets, and prognostic factors
title_auth	Current research in head and neck cancer molecular pathways, novel therapeutic targets, and prognostic factors
title_exact_search	Current research in head and neck cancer molecular pathways, novel therapeutic targets, and prognostic factors
title_full	Current research in head and neck cancer molecular pathways, novel therapeutic targets, and prognostic factors volume editor: Henning Bier
title_fullStr	Current research in head and neck cancer molecular pathways, novel therapeutic targets, and prognostic factors volume editor: Henning Bier
title_full_unstemmed	Current research in head and neck cancer molecular pathways, novel therapeutic targets, and prognostic factors volume editor: Henning Bier
title_short	Current research in head and neck cancer
title_sort	current research in head and neck cancer molecular pathways novel therapeutic targets and prognostic factors
title_sub	molecular pathways, novel therapeutic targets, and prognostic factors
topic	Otorhinolaryngology Oncology Cell Biology Immunology Molecular Biology Krebs Medizin (DE-588)4073781-0 gnd Kopfregion (DE-588)4132084-0 gnd Halsregion (DE-588)4113837-5 gnd
topic_facet	Otorhinolaryngology Oncology Cell Biology Immunology Molecular Biology Krebs Medizin Kopfregion Halsregion Aufsatzsammlung
url	https://karger.com/books/book/2486
volume_link	(DE-604)BV037287951
work_keys_str_mv	AT bierhenning currentresearchinheadandneckcancermolecularpathwaysnoveltherapeutictargetsandprognosticfactors

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