Verfügbarkeit: CD14 in the inflammatory response

CD14 in the inflammatory response:

In a world full of pathogens the ability to detect an incipient infection and to respond rapidly and appropriately to it is a decisive part of our survival strategy. The innate immune system provides the first response to an infection by initiating an inflammatory response and the monocyte surface m...

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Weitere Verfasser:	Jack, Robert (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Basel Karger 2000
Schriftenreihe:	Chemical immunology Vol. 74
Schlagworte:	Immunology Biochemistry Cell Biology Molecular Biology Infectious Diseases Entzündung Immunreaktion Antigen CD14 Aufsatzsammlung
Online-Zugang:	BFB01 BSB01 BTW01 EUV01 FAN01 FAW01 FFW01 FHI01 FHM01 FHN01 FHR01 FKE01 FNU01 FWS01 FWS02 GEM01 LCO01 SAB01 SAM01 SBG01 SBR01 SND01 TUM01 UBA01 UBG01 UBM01 UBR01 UBT01 UBW01 UER01 UPA01 Volltext
Zusammenfassung:	In a world full of pathogens the ability to detect an incipient infection and to respond rapidly and appropriately to it is a decisive part of our survival strategy. The innate immune system provides the first response to an infection by initiating an inflammatory response and the monocyte surface molecule CD14 is a key element in this response system. The initial chapters in this volume describe the structure and ligand interactions of this important receptor molecule which is involved both in inflammation and in some aspects of apoptosis. The very recent results which illuminate the probable signal transduction pathways are also described. Overactivation of the inflammatory response can lead to systemic inflammation and septic shock. Attempts to intervene clinically in this system have been disappointing, and the reasons for these failures are discussed in the context of the expression of TNF which is upregulated by CD14. A discussion of new data on the clinical course of shock and the currently emerging therapeutic strategies rounds off the book. The information compiled in this well-edited volume will be of use to everyone working on problems of inflammation - a topic where fundamental research and clinical medicine meet. Clinicians will find the current state of scientific knowledge on the inflammatory response as induced via CD14 presented in a readable form, while the clinical aspects discussed will be of particular interest to scientists and students who lack a medical background
Beschreibung:	1 Online-Ressource (VIII, 182 Seiten) Illustrationen, Diagramme
ISBN:	9783318004632

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genre	(DE-588)4143413-4 Aufsatzsammlung gnd-content
genre_facet	Aufsatzsammlung
id	DE-604.BV036069057
illustrated	Not Illustrated
indexdate	2024-08-01T11:41:30Z
institution	BVB
isbn	9783318004632
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-018960362
oclc_num	728410632
open_access_boolean
owner	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-1046 DE-578
owner_facet	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-1046 DE-578
physical	1 Online-Ressource (VIII, 182 Seiten) Illustrationen, Diagramme
psigel	ZDB-1-KEB
publishDate	2000
publishDateSearch	2000
publishDateSort	2000
publisher	Karger
record_format	marc
series	Chemical immunology
series2	Chemical immunology
spellingShingle	CD14 in the inflammatory response Chemical immunology Immunology Biochemistry Cell Biology Molecular Biology Infectious Diseases Entzündung (DE-588)4014975-4 gnd Immunreaktion (DE-588)4133841-8 gnd Antigen CD14 (DE-588)4436094-0 gnd
subject_GND	(DE-588)4014975-4 (DE-588)4133841-8 (DE-588)4436094-0 (DE-588)4143413-4
title	CD14 in the inflammatory response
title_auth	CD14 in the inflammatory response
title_exact_search	CD14 in the inflammatory response
title_full	CD14 in the inflammatory response volume editor: Robert S. Jack
title_fullStr	CD14 in the inflammatory response volume editor: Robert S. Jack
title_full_unstemmed	CD14 in the inflammatory response volume editor: Robert S. Jack
title_short	CD14 in the inflammatory response
title_sort	cd14 in the inflammatory response
topic	Immunology Biochemistry Cell Biology Molecular Biology Infectious Diseases Entzündung (DE-588)4014975-4 gnd Immunreaktion (DE-588)4133841-8 gnd Antigen CD14 (DE-588)4436094-0 gnd
topic_facet	Immunology Biochemistry Cell Biology Molecular Biology Infectious Diseases Entzündung Immunreaktion Antigen CD14 Aufsatzsammlung
url	https://karger.com/books/book/2334
volume_link	(DE-604)BV022500180
work_keys_str_mv	AT jackrobert cd14intheinflammatoryresponse

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