Gene and cell therapy: therapeutic mechanisms and strategies
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Boca Raton [u.a.]
CRC Press
2009
|
| Edition: | 3. ed. |
| Subjects: | |
| Online Access: | Table of contents only Inhaltsverzeichnis |
| Physical Description: | XVIII, 1101 S. Ill., graph. Darst. |
| ISBN: | 9780849387685 |
Staff View
MARC
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Record in the Search Index
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| adam_text | Contents
Foreword ix
Preface xi
Editor xiii
Contributors xv
PART I Delivery Systems and Therapeutic Strategies
Chapter 1 Retroviral Vectors for Cell and Gene Therapy 3
Axel Schambach, Tobias Maetzig, and Christopher Baum
Chapter 2 Production of Retroviral Vectors: From the Producer Cell to the Final Product 17
Pedro E. Cruz, Ana S. Coroadinha, Teresa Rodrigues, and Hansjorg Hauser
Chapter 3 Adenovirus Vectors for Gene Therapy 39
Neil R. Hackett and Ronald G. Crystal
Chapter 4 Modified Adenoviruses for Gene Therapy 69
Joel N. Glasgow, Akseli Hemminki, and David T. Curiel
Chapter 5 Helper-Dependent Adenoviral Vectors for Gene Therapy 87
Nicola Brunetti-Pierri and Philip Ng
Chapter 6 Adeno-Associated Virus and AAV Vectors for Gene Delivery 115
Barrie J. Carter, Haim Burstein, and Richard W. Peluso
Chapter 7 Therapeutic Gene Transfer with Replication-Defective Herpes Simplex Viral Vectors 159
D. Wolfe, W.F. Goins, A.R. Frampton, Jr., Marina Mata, D.J. Fink, andJ.C. Glorioso
Chapter 8 Oncolytic Viruses for Treatment of Cancer 193
Mari Raki, Maria Rajecki, David Kirn, and Akseli Hemminki
Chapter 9 Lentiviral Vectors 207
John M. Felder III and Richard E. Sutton
Chapter 10 Vaccinia Viral Vectors 245
J. Andrea McCart and David L. Bartlett
Chapter 11 Baculovirus-Mediated Gene Transfer: An Emerging Universal Concept 263
Kari J. Airenne, Anssi J. Mdhonen, Olli H. Laitinen, and Seppo Yld-Herttuala
v
vi
Chapter 12 Bacterial Vector in Gene Therapy 293
Ming-Shen Dai and Georges Vassaux
Chapter 13 Redox-Responsive Polymer-Based Gene Delivery Systems 309
David Oupicky, Ye-Zi You, and Devika Soundara Manickam
Chapter 14 Polymers and Dendrimers for Gene Delivery in Gene Therapy 321
Ijeoma F. Uchegbu, Christine Dufes, Pei Lee Kan, and Andreas G. Schatzlein
Chapter 15 Receptor-Targeted Polyplexes for DNA and siRNA Delivery 341
Alexander Philipp and Ernst Wagner
Chapter 16 Electroporation of Plasmid-Based Vaccines and Therapeutics 363
Ruxandra Draghia-Akli and Amir S. Khan
Chapter 17 Magnetofection: Using Magnetic Particles and Magnetic Force to Enhance
and to Target Nucleic Acid Delivery 379
Franz Scherer and Christian Plank
Chapter 18 Biolistic and Other Needle-Free Delivery Systems 405
MarkA.F. Kendall
Chapter 19 Optimization of Nonviral Gene Therapeutics 423
Nancy Smyth Templeton
Chapter 20 Photochemical Internalization: A Technology for Efficient and Site-Specific Gene Delivery 435
Anette Bonsted, Anders Hfigset, and Kristian Berg
Chapter 21 Interactions in Macromolecular Complexes Used as Nonviral Vectors for Gene Delivery 443
Rudolf Podgomik, Daniel Harries, Jason DeRouchey, Hemult H. Strey, and V. Adrian Parsegian
PART II Other Therapeutic Strategies
Chapter 22 In Vivo Applications of Morpholino Oligonucleotides 487
JeffS. Isenberg, William A. Frazier, and David D. Roberts
Chapter 23 Antisense Oligonucleotide-Based Therapeutics 497
C. Frank Bennett, Eric Swayze, Richard Geary, Scott Henry, Lloyd Tillman, and Greg Hardee
Chapter 24 Development of RNAi Therapeutics 523
Antonin R. de Fougerolles
Chapter 25 Suicide Gene Therapy 539
Nikiforos Balkan, Bert W. O Malley Jr., and F. Charles Brunicardi
vii
Chapter 26 Selectable Markers for Gene Therapy 555
Jean-Pierre Gillet, Chava Kimchi-Sarfaty, Shiri Shinar, Thomas Licht, Caroline Lee,
Peter Hafkemeyer, Christine A. Hrycyna, Ira Pastan, and Michael M. Gottesman
Chapter 27 Embryonic Stem Cells and Their Application in Regenerative Medicine and Tissue Engineering 581
Nicholas D. Evans and Julia M. Polak
Chapter 28 Polymeric Nano- and Microparticles for the Delivery of Antisense Oligonucleotides and siRNA 599
Elias Fattal and Giuseppe De Rosa
PART III Gene Expression and Detection
Chapter 29 Deliberate Regulation of Therapeutic Transgenes 619
Nuria Vilaboa and Richard Voellmy
Chapter 30 Monitoring Gene and Cell Therapies in Living Subjects with Molecular Imaging Technologies 637
Sunetra Ray, Sandip Biswal, and Sanjiv Sam Gambhir
Chapter 31 Nonviral Genome Modification Strategies for Gene Therapy: Transposon, Integrase,
and Homologous Recombination Systems 677
Lauren E. Woodard and Michele P. Calos
PART IV Disease Targets and Therapeutic Strategies
Chapter 32 Hematopoietic Progenitor Cells 695
• Kuan-Yin Karen Lin, Olga Sirin, and Margaret A. Goodell
Chapter 33 Gene Therapy for Hematopoietic Disorders 713
Elizabeth M. Kang, Mitchell E. Horwitz, and Harry L. Malech
Chapter 34 Use of Genetically Modified Stem Cells in Experimental Gene Therapies 731
Thomas P. Zwaka
Chapter 35 Cardiovascular Gene and Cell Therapy 737
Kazuhiro Oka
Chapter 36 Gene Therapy for Cancer 761
Karsten Brand
Chapter 37 Molecular Therapy for Type 1 and Type 2 Diabetes 801
Susan Leanne Samson, Vijay Yechoor, and Lawrence Chan
Chapter 38 Progress toward Gene Therapy for Cystic Fibrosis 817
Ruth S. Everett and Larry G. Johnson
viii
Chapter 39 Gene Therapy for Neurological Diseases 833
William J. Bowers, Suresh de Silva, and Howard J. Federoff
Chapter 40 Principles of Gene Therapy for Inborn Errors of Metabolism 869
Jon A. Wolff and Cary O. Harding
Chapter 41 RNA Interference-Based Gene Therapy Strategies for the Treatment of HIV Infection 881
Lisa J. Scherer and John J. Rossi
Chapter 42 Cutaneous Gene Transfer: Cell and Gene Therapy of Skin and Systemic Disorders 889
William Buitrago and Dennis R. Roop
Chapter 43 Gene Therapy for Childhood Onset Blindness 913
Matthew C. Canver and Jean Bennett
Chapter 44 DNA Vaccines 921
Jian Yan and David B. Weiner
Chapter 45 Immunoisolation for CNS Cell Therapy 949
Dwaine F. Emerich and Christopher G. Thanos
PART V Clinical Trials and Regulatory Issues
Chapter 46 Cardiovascular Gene Therapy 975
Jorn Tongers, Jerome G. Roncalli, and Douglas W. Losordo
Chapter 47 Gene Therapy for the Treatment of Cancer: From Laboratory to Bedside 1001
Gianpietro Dotti, Barbara Savoldo, Fatma Okur, Raphael F. Rousseau, and Malcolm K. Brenner
Chapter 48 p53 Tumor Suppressor Opens Gateways for Cancer Therapy 1019
Mu-Shui Dai, Jayme R. Gallegos, and Hua Lu
Chapter 49 Recombinant Adenoviral-p53 Agent for Treatment of Cancers 1033
Zhaohui Peng, Qing Yu, andJingyaZhu
Chapter 50 Gene Marking Studies of Hematopoietic Cells 1057
Catherine M. Bollard, SiokK. Tey, Malcolm K. Brenner, and Helen E. Heslop
Chapter 51 Regulatory Aspects of Gene Therapy 1071
Stephanie L. Simek and Lilia Bi
Index 1087
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| isbn | 9780849387685 |
| language | English |
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| physical | XVIII, 1101 S. Ill., graph. Darst. |
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| spelling | Gene and cell therapy therapeutic mechanisms and strategies ed. by Nancy Smyth Templeton 3. ed. Boca Raton [u.a.] CRC Press 2009 XVIII, 1101 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Gene therapy Cellular therapy Gene Therapy methods Cell Transplantation methods Frischzellentherapie (DE-588)4067560-9 gnd rswk-swf Gentherapie (DE-588)4296957-8 gnd rswk-swf Gentherapie (DE-588)4296957-8 s DE-604 Frischzellentherapie (DE-588)4067560-9 s Templeton, Nancy Smyth 1952- Sonstige (DE-588)136556116 oth http://www.loc.gov/catdir/toc/ecip0813/2008011642.html Table of contents only HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018937451&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gene and cell therapy therapeutic mechanisms and strategies Gene therapy Cellular therapy Gene Therapy methods Cell Transplantation methods Frischzellentherapie (DE-588)4067560-9 gnd Gentherapie (DE-588)4296957-8 gnd |
| subject_GND | (DE-588)4067560-9 (DE-588)4296957-8 |
| title | Gene and cell therapy therapeutic mechanisms and strategies |
| title_auth | Gene and cell therapy therapeutic mechanisms and strategies |
| title_exact_search | Gene and cell therapy therapeutic mechanisms and strategies |
| title_full | Gene and cell therapy therapeutic mechanisms and strategies ed. by Nancy Smyth Templeton |
| title_fullStr | Gene and cell therapy therapeutic mechanisms and strategies ed. by Nancy Smyth Templeton |
| title_full_unstemmed | Gene and cell therapy therapeutic mechanisms and strategies ed. by Nancy Smyth Templeton |
| title_short | Gene and cell therapy |
| title_sort | gene and cell therapy therapeutic mechanisms and strategies |
| title_sub | therapeutic mechanisms and strategies |
| topic | Gene therapy Cellular therapy Gene Therapy methods Cell Transplantation methods Frischzellentherapie (DE-588)4067560-9 gnd Gentherapie (DE-588)4296957-8 gnd |
| topic_facet | Gene therapy Cellular therapy Gene Therapy methods Cell Transplantation methods Frischzellentherapie Gentherapie |
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