Autologous techniques to fill bone defects for acute fractures and nonunions:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Philadelphia, PA
Saunders
2010
|
Schriftenreihe: | Orthopedic clinics of North America
41,1 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Includes bibliographical references and index Bone defects caused by high-energy injuries, bone loss, infected nonunions, and nonunions / Andrea Wiese and Hans C. Pape -- Viable bone and circulatory factors required for survival of bone grafts / Lisa K. Cannada -- Use of solid and cancellous autologous bone graft for fractures and nonunions / James T. Marino and Bruce H. Ziran -- The concept of induced membrane for reconstruction of long bone defects / Alain C. Masquelet and Thierry Begue -- Clinical use of resorbable polymeric membranes in the treatment of bone defects / Richard P. Meinig -- Use of the induced membrane technique for bone tissue engineering purposes : animal studies / Véronique Viateau ... [et al.] -- Biological rationale for the intramedullary canal as a source of autograft material / David J. Hak and Jason L. Pittman -- Treatment of large segmental bone defects with reamer-irrigator-aspirator bone graft : technique and case series / Todd A. McCall ... [et al.] -- Autograft and nonunions : morbidity with intramedullary bone graft versus iliac crest bone graft / Janet D. Conway -- Autologous bone graft : when shall we add growth factors? / Peter V. Giannoudis and Haralampos T. Dinopoulos -- Quantitative analysis of growth factors from a second filter using the reamer-irrigator-aspirator system : description of a novel technique / James P. Stannard ... [et al.] -- RIA : one community's experience / Christopher G. Finkemeier, Rafael Neiman, and Domingo Hallare -- Managing bone deficiency and nonunions of the proximal femur / John J. Perry, Brent Winter, and Jeffrey W. Mast -- Soft tissue and biomechanical challenges encountered with the management of distal tibia nonunions / Ivan S. Tarkin, Peter A. Siska, and Boris A. Zelle |
Beschreibung: | XIII, 130 S. zahlr. Ill., graph. Darst. 26 cm |
ISBN: | 9781437718478 |
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500 | |a Bone defects caused by high-energy injuries, bone loss, infected nonunions, and nonunions / Andrea Wiese and Hans C. Pape -- Viable bone and circulatory factors required for survival of bone grafts / Lisa K. Cannada -- Use of solid and cancellous autologous bone graft for fractures and nonunions / James T. Marino and Bruce H. Ziran -- The concept of induced membrane for reconstruction of long bone defects / Alain C. Masquelet and Thierry Begue -- Clinical use of resorbable polymeric membranes in the treatment of bone defects / Richard P. Meinig -- Use of the induced membrane technique for bone tissue engineering purposes : animal studies / Véronique Viateau ... [et al.] -- Biological rationale for the intramedullary canal as a source of autograft material / David J. Hak and Jason L. Pittman -- Treatment of large segmental bone defects with reamer-irrigator-aspirator bone graft : technique and case series / Todd A. McCall ... [et al.] -- Autograft and nonunions : morbidity with intramedullary bone graft versus iliac crest bone graft / Janet D. Conway -- Autologous bone graft : when shall we add growth factors? / Peter V. Giannoudis and Haralampos T. Dinopoulos -- Quantitative analysis of growth factors from a second filter using the reamer-irrigator-aspirator system : description of a novel technique / James P. Stannard ... [et al.] -- RIA : one community's experience / Christopher G. Finkemeier, Rafael Neiman, and Domingo Hallare -- Managing bone deficiency and nonunions of the proximal femur / John J. Perry, Brent Winter, and Jeffrey W. Mast -- Soft tissue and biomechanical challenges encountered with the management of distal tibia nonunions / Ivan S. Tarkin, Peter A. Siska, and Boris A. Zelle | ||
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adam_text | Titel: Autologous techniques to fill bone defects for acute fractures and nonunions
Autor: Pape, Hans-Christoph
Jahr: 2010
Autologous Techniques to Fill Bone Defects for Acute Fractures and Nonunions
Contents
Preface xiii
Hans C. Pape and Timothy G. Weber
Bone Defects Caused by High-energy Injuries, Bone Loss, Infected Nonunions,
and Nonunions
Andrea Wiese and Hans C. Pape
Bone defects represent a difficult problem for the clinician. They entail a sustained
increase in hospitalization, risk of complications, and associated increase in ex-
penses. This article discusses bone defects caused by high-energy injuries, bone
loss, infected nonunions, and nonunions.
Viable Bone and Circulatory Factors Required for Survival of Bone Grafts
Lisa K. Cannada
The healing of fractures and nonunions has significant science background to it;
however, the application of the products in the surgeon s hands should be consid-
ered an art in the science of bone healing. The surgeon must choose adequate fix-
ation for stability and to promote healing by not making the construct too stiff. If
a bone graft substitute is necessary, the surgeon must choose the type of bone graft
substitute depending on patient factors and surgeon factors involving the treatment
of the fracture.
Use of Solid and Cancellous Autologous Bone Graft for Fractures and Nonunions 15
James T Marino and Bruce H. Ziran
Bone is the second most commonly implanted material in the human body, after
blood transfusion, with an estimated 600,000 grafts performed annually. Although
the market for bone graft substitutes is more than $1 billion, that of bone graft itself
is still more than half that amount. Reports of autologous bone grafting date back to
the ancient Egyptians, yet the modern scientific study of grafting began in the early
19th century. Since then, the indications, methodology, and science of bone grafts in
nonunion and bone loss have been established and refined, and new methods of
harvesting and treatment are being developed and implemented. This article de-
scribes the use of solid and cancellous bone graft in the treatment of acute bone
loss and nonunion.
The Concept of Induced Membrane for Reconstruction of Long Bone Defects 27
Alain C. Masqueletand Thierry Begue
Clinical, experimental, and fundamental studies have shown the interest of a foreign
body-induced membrane to promote the consolidation of a conventional cancellous
bone autograft for reconstruction of long bone defects. The main properties of the
membrane are to prevent the resorption of the graft and to secrete growth factors.
The induced membrane appears as a biological chamber, which allows the concep-
tion of numerous experimental models of bone reconstruction. This concept could
probably be extended to other tissue repair.
Contents
Clinical Use of Resorbable Polymeric Membranes in theTreatment of Bone Defects 39
Richard P. Meinig
The reconstruction of large bone defects remains a clinically challenging condition.
Although many treatment approaches exist, they all have limitations. Recently, bio-
resorbable polylactide membranes have become commercially available. These
membranes, when applied to bone defects, enhance bone healing by direct osteo-
conduction, exclusion of nonosseous tissues, and enhancing the osteogenic envi-
ronment for autologous grafts. When combined with appropriate internal fixation
and autologous bone graft, bioresorbable polylactide membranes allow for single-
step reconstruction of large bone defects.
Use of the Induced Membrane Technique for Bone Tissue Engineering Purposes:
Animal Studies 49
VeroniqueViateau, Morad Bensidhoum, GenevFve Guillemin, Herve Petite, Didier Hannouche,
Fani Anagnostou, and Philippe Pelissier
Animal experiments using the induced membrane procedure for bone tissue
engineering purposes have provided evidence that the membrane has structural
characteristics and biologic properties that may be used for bone tissue engineering
purposes. Clinically relevant animal models have demonstrated that standardized
particulate bone constructs can be used to repair large bone defects using the pro-
cedure and that the osteogenic ability of these constructs partially approaches that
of bone autografts.
Biological Rationale for the Intramedullary Canal as a Source of Autograft Material 57
David J. Hak and Jason L. Pittman
Bone harvested by intramedullary reaming offers a minimally invasive alternative to
harvesting bone from the iliac crest, which has long been considered the gold stan-
dard for autogenous bone grafting. The biologic potential of intramedullary reaming
material has been studied both in vitro and in vivo. The material provides osteogenic,
osteoinductive, and osteoconductive properties that are comparable to the material
harvested from the iliac crest. In addition to the ability to obtain a large volume of
bone, the graft harvested by the Reamer-lrrigator-Aspirator has been shown to be
rich in growth factors, including BMP-2, TGF-J31, IGF-I, FGFa, and PDGFbb.
Treatment of Large Segmental Bone Defects with Reamer-lrrigator-Aspirator Bone Graft:
Technique and Case Series 63
Todd A. McCall, David S. Brokaw, Bradley A. Jelen, D. Kevin Scheid, Angela V. Scharfenberger,
Dean C. Maar, James M. Green, Melanie R. Shipps, Marcus B. Stone, Dana Musapatika,
and Timothy G. Weber
Treatment of large segmental defects using conventional autogenous iliac crest
bone graft can be limited by volume of cancellous bone and donor site morbidity.
The reamer-irrigator-aspirator (RIA) technique allows access to a large volume of
cancellous bone graft containing growth factors with potency equal to or greater
than autograft material from the iliac crest. The purpose of this study was to evaluate
the effectiveness of RIA-harvested autogenous bone graft for treating large segmen-
tal defects of long bones.
Contents
Autograft and Nonunions: Morbidity with Intramedullary Bone Graft versus Iliac
Crest Bone Graft 75
Janet D. Conway
This article focuses on comparing patient morbidity with harvesting bone graft for
the treatment of nonunions from three different sites. Anterior iliac crest graft is
the most commonly used site; however, the posterior iliac crest and intramedullary
canal provide greater quantities of bone. The anterior and posterior iliac crests also
have some donor site complications such as nerve injury and persistent pain. The
intramedullary canal, when compared with anterior and posterior iliac crest, offers
the largest quantity of bone graft with the least amount of patient donor site morbid-
ity. The intramedullary canal also appears to be a bone graft source that can be re-
harvested, unlike the anterior and posterior iliac crest donor sites.
Autologous Bone Graft: When Shall We Add Growth Factors? 85
Peter V. Giannoudisand HaralamposT. Dinopoulos
Although the unquestionable value of autologous bone grafting and the analogous
value of the reaming by-products in nonunion treatment have been mentioned ex-
tensively in the literature, there is ongoing vivid discussion for the treatment of those
case scenarios where the fracture nonunion is complicated by other local environ-
ment adverse circumstances. The graft expansion with growth factors as the
bone morphogenetic proteins (BMPs) offers the possibility to reduce the number
of operative procedures, complications, length of hospital stay, and time to union.
In this article, we consider the potential clinical scenarios for graft expansion with
BMPs.
Quantitative Analysis of Growth Factors from a Second Filter Using the
Reamer-lrrigator-Aspirator System: Description of a Novel Technique 95
James P. Stannard, Ashoke K. Sathy, Fariba Moeinpour, Rena L. Stewart, and David A.Volgas
Use of the Reamer-lrrigator-Aspirator (RIA) as a source of autogenous bone graft in
the treatment of nonunions is increasing. We report on our novel technique of using
a second filter containing beta-tricalcium phosphate (TCP) as a graft extender while
using the RIA system. We also quantify growth factor concentrations in the collec-
tions from the TCP filter. A second filter attached in series with the standard RIA fil-
tration system yields TCP with substantial concentrations of bioactive proteins that
are equal to those seen in the bone graft that is harvested in the first filter.
RIA: One Community s Experience 99
Christopher G. Finkemeier, Rafael Neiman, and Domingo Hallare
The Reamer Irrigator Aspirator (RIA) has three main indications in our community
trauma practice. The most common indication for RIA is harvesting of autologous
bone graft from the femur for nonstructural bone graft. The second most common
indication is for irrigation and debridement of intramedullary osteomyelitis. The final
indication for RIA is for acute nailing of femoral shaft fractures in patients with mul-
tiple long bone fractures with or without pulmonary injury. If one pays careful atten-
tion to the details of the technique, RIA is a safe and effective method of harvesting
autologous bone graft with minimal morbidity. Autologous bone graft harvested with
RIA is our graft of choice for nearly all of our bone grafting cases.
Contents
Managing Bone Deficiency and Nonunions of the Proximal Femur 105
John J. Perry, BrentWinter, andJeffrey W. Mast
Revision surgery of the proximal femur with bone loss secondary to failed cephalo-
medullary nails is problematic and becoming more prevalent as their use grows. This
article presents a technique of deformity correction, bone graft techniques that re-
constitute residual defects, and definitive fixation using load-sharing devices that
provide immediate stability for bone healing and early rehabilitation. Preoperative
planning and the potential advantages and disadvantages of newer fixed-angled
plates versus established implants are discussed. With proper planning, surgical ex-
ecution with proved techniques, augmented by the addition of newer graft harvest-
ing techniques, anatomic restoration, and bone reconstitution with healing, has
invariably been the result.
Soft Tissue and Biomechanical Challenges Encountered with the Management
of Distal Tibia Nonunions 119
Ivan S.Tarkin, Peter A. Siska, and Boris A. Zelle
A thoughtful treatment algorithm is required to optimally treat distal tibia nonunion. A
healthy respect for the tenuous soft tissue envelope, compromised vascularity, and
challenging mechanical environment is advisable. Achieving osseous union and im-
proved functionality requires an individualized plan of care based on the personality
of the nonunion and host. Attention must be focused on providing mechanical sta-
bility at the site of nonunion and providing biologic supplementation.
Index 127
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physical | XIII, 130 S. zahlr. Ill., graph. Darst. 26 cm |
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spelling | Autologous techniques to fill bone defects for acute fractures and nonunions guest ed. Hans C. Pape ; Timothy G. Weber Philadelphia, PA Saunders 2010 XIII, 130 S. zahlr. Ill., graph. Darst. 26 cm txt rdacontent n rdamedia nc rdacarrier Orthopedic clinics of North America 41,1 Includes bibliographical references and index Bone defects caused by high-energy injuries, bone loss, infected nonunions, and nonunions / Andrea Wiese and Hans C. Pape -- Viable bone and circulatory factors required for survival of bone grafts / Lisa K. Cannada -- Use of solid and cancellous autologous bone graft for fractures and nonunions / James T. Marino and Bruce H. Ziran -- The concept of induced membrane for reconstruction of long bone defects / Alain C. Masquelet and Thierry Begue -- Clinical use of resorbable polymeric membranes in the treatment of bone defects / Richard P. Meinig -- Use of the induced membrane technique for bone tissue engineering purposes : animal studies / Véronique Viateau ... [et al.] -- Biological rationale for the intramedullary canal as a source of autograft material / David J. Hak and Jason L. Pittman -- Treatment of large segmental bone defects with reamer-irrigator-aspirator bone graft : technique and case series / Todd A. McCall ... [et al.] -- Autograft and nonunions : morbidity with intramedullary bone graft versus iliac crest bone graft / Janet D. Conway -- Autologous bone graft : when shall we add growth factors? / Peter V. Giannoudis and Haralampos T. Dinopoulos -- Quantitative analysis of growth factors from a second filter using the reamer-irrigator-aspirator system : description of a novel technique / James P. Stannard ... [et al.] -- RIA : one community's experience / Christopher G. Finkemeier, Rafael Neiman, and Domingo Hallare -- Managing bone deficiency and nonunions of the proximal femur / John J. Perry, Brent Winter, and Jeffrey W. Mast -- Soft tissue and biomechanical challenges encountered with the management of distal tibia nonunions / Ivan S. Tarkin, Peter A. Siska, and Boris A. Zelle Bones / Abnormalities Autografts Autotransplantation Bone Transplantation Bone and Bones / abnormalities Bone and Bones / injuries Bone and Bones / surgery Bone and Bones abnormalities Bone and Bones injuries Bone and Bones surgery Bones Abnormalities Pape, Hans-Christoph 1962- Sonstige (DE-588)12989155X oth Orthopedic clinics of North America 41,1 (DE-604)BV000001089 41,1 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018801095&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Autologous techniques to fill bone defects for acute fractures and nonunions Orthopedic clinics of North America Bones / Abnormalities Autografts Autotransplantation Bone Transplantation Bone and Bones / abnormalities Bone and Bones / injuries Bone and Bones / surgery Bone and Bones abnormalities Bone and Bones injuries Bone and Bones surgery Bones Abnormalities |
title | Autologous techniques to fill bone defects for acute fractures and nonunions |
title_auth | Autologous techniques to fill bone defects for acute fractures and nonunions |
title_exact_search | Autologous techniques to fill bone defects for acute fractures and nonunions |
title_full | Autologous techniques to fill bone defects for acute fractures and nonunions guest ed. Hans C. Pape ; Timothy G. Weber |
title_fullStr | Autologous techniques to fill bone defects for acute fractures and nonunions guest ed. Hans C. Pape ; Timothy G. Weber |
title_full_unstemmed | Autologous techniques to fill bone defects for acute fractures and nonunions guest ed. Hans C. Pape ; Timothy G. Weber |
title_short | Autologous techniques to fill bone defects for acute fractures and nonunions |
title_sort | autologous techniques to fill bone defects for acute fractures and nonunions |
topic | Bones / Abnormalities Autografts Autotransplantation Bone Transplantation Bone and Bones / abnormalities Bone and Bones / injuries Bone and Bones / surgery Bone and Bones abnormalities Bone and Bones injuries Bone and Bones surgery Bones Abnormalities |
topic_facet | Bones / Abnormalities Autografts Autotransplantation Bone Transplantation Bone and Bones / abnormalities Bone and Bones / injuries Bone and Bones / surgery Bone and Bones abnormalities Bone and Bones injuries Bone and Bones surgery Bones Abnormalities |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018801095&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV000001089 |
work_keys_str_mv | AT papehanschristoph autologoustechniquestofillbonedefectsforacutefracturesandnonunions |