Molecular diagnostics:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, Acad. Press
2010
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVII, 598 S. Ill., graph. Darst. |
| ISBN: | 9780123745378 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV035857325 | ||
| 003 | DE-604 | ||
| 005 | 20100610 | ||
| 007 | t | ||
| 008 | 091202s2010 ad|| |||| 00||| eng d | ||
| 020 | |a 9780123745378 |9 978-0-12-374537-8 | ||
| 035 | |a (OCoLC)423582260 | ||
| 035 | |a (DE-599)HBZHT016121490 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-20 |a DE-19 | ||
| 050 | 0 | |a RB43.7 | |
| 082 | 0 | |a 616.0756 |2 22 | |
| 084 | |a YV 1200 |0 (DE-625)154210: |2 rvk | ||
| 245 | 1 | 0 | |a Molecular diagnostics |c ed. by George P. Patrinos ... |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier, Acad. Press |c 2010 | |
| 300 | |a XVII, 598 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 2 | |a Molecular Diagnostic Techniques | |
| 650 | 2 | |a Genetic Screening | |
| 650 | 4 | |a Genetic Testing | |
| 650 | 4 | |a Genetic screening | |
| 650 | 4 | |a Molecular Diagnostic Techniques | |
| 650 | 4 | |a Molecular diagnosis | |
| 650 | 0 | 7 | |a Labormedizin |0 (DE-588)4073931-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Molekulare Diagnostik |0 (DE-588)4589005-5 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Molekulare Diagnostik |0 (DE-588)4589005-5 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Labormedizin |0 (DE-588)4073931-4 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a Patrinos, George P. |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018715246&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-018715246 | |
Datensatz im Suchindex
| _version_ | 1809493932225069056 |
|---|---|
| adam_text |
Titel: Molecular diagnostics
Autor: Patrinos, George P.
Jahr: 2010
List of Contributors ix
Preface - First Edition xiii
Preface - Second Edition xv
Foreword - First Edition xvii
1. Molecular Diagnostics: Past, Present,
and Future 1
George P. Patrinos and Wilhelm /. Ansorge
Section I
Molecular Diagnostic Technology 13
2. Allele-Specific Mutation Detection 15
Aglaia Athanassiadou, Eleana F. Stavrou,
Adamandia Papachatzopoulou and
George P. Patrinos
3. Enzymatic and Chemical Cleavage
Methods to Identify Genetic
Variation 29
Chinh T. Bui, Emmanuelle Nicolas, Georgina
Sallmann, Maria Chiotis, Andreana Lambrinakos,
Kylee Rees, Ian Trounce, Richard G.H. Cotton,
Lauryn Blakesley, Andrew K. Godwin and
Anthony T. Yeung
4. Mutation Detection by Single Strand
Conformation Polymorphism and
Heteroduplex Analysis 45
Panayiotis G. Menounos and
George P. Patrinos \
5. Capillary Electrophoresis 59
Anja Bosserhoff and Claus Hellerbrand
6. Temperature and Denaturing
Gradient Gel Electrophoresis 75
Hartmut Peters and Peter N. Robinson
7. Real-Time Polymerase Chain
Reaction 87
Lut Overbergh, Anna-Paula Giulietti,
Dirk Valckx and Chantal Mathieu
8. Pyrosequencing 107
Sharon Marsh
f Contents j—
9. Application of Padlock and Selector
Probes in Molecular Medicine 117
Mats Nilsson, Chatarina Larsson, johan
Stenberg, Jenny Goransson, Ida Grundberg,
Magnus Ssaksson, Tim Conze and
Sara Henriksson
10. Molecular Cytogenetics in
Molecular Diagnostics 133
Holger Tonnies
11. Analysis of Human Splicing
Defects Using Hybrid Minigenes 155
Franco Pagani and Francisco E. liaralh*
12. Detection of Genomic Duplications
and Deletions 171
Graham R. Taylor and Giro/ A. Delancy
13. Multiplex Ligation-Dependent Probe
Amplification (MLPA) and Methylation-
Specific (MS)-MLPA: Multiplex
Detection of DNA/mRNA
Copy Number and
Methylation Changes 183
Eline M. Sepers and /an P. Schouten
14. Molecular Techniques for DNA
Methylation Studies 199
lorg Fost and Ivo G. Gut
15. High-Resolution Melting Curve
Analysis for Molecular Diagnostics 229
lared S. Farrar, Gudrun II. Reed and
Gar I T. Wittwvr
16. DNA Microarrays and
Genetic Testing 247
Lars Dvrskjot, Karina Dalsgaard-Si rvns?n.
Marie Stampe-Ostenteld, Karin Birkenkamp-
Demtroder, Kaspcr Thar sen. Glaus L. Andersen,
Mogens Kruhofier, lens L Jensen and
Tor ben F. Orntoft
v
' vi ^
17. Arrayed Primer Extension Microarrays 26.
for Molecular Diagnostics 267
Neeme Tonisson, Eneli Oitmaa,
Kaarel Krjutskov, Janne Pullat, llona Lind,
Merike Leego, Ants Kurg and Andres Metspalu
27.
18. Application of Proteomics to
Disease Diagnostics 285
Samir Hanash, )i Qiu and Vitor Faca
28.
19. RNA-Based Variant Detection: The
Protein Truncation Test 293
Johan T. den Dunnen
20. Protein Diagnostics by Proximity
Ligation: Combining Multiple
Recognition and DNA Amplification
for Improved Protein Analyses 299
Karl-johan Leuchowius, Ola Soderberg,
Masood Kamali-Moghaddam, Malin jarvius, „ _
Irene Weibrecht, Katerina Pardali and
Ulf Landegren
21. Mass Spectrometry and its
Applications to Functional
Proteomics 307 31-
Thomas Kocher and Ciulio Supertl-Furga
Section II
Applications of Molecular 32
Diagnostics and Related Issues 325
22. Pharmacogenetics and
Pharmacogenomics: Impact on
Drug Discovery and Clinical Care 327
Minoli Perera and Federlco Innocent! _„
23. Nutrigenomics: Integrating
Genomic Approaches into
Nutrition Research 347
Lynette R. Ferguson, Martin Philpott and
Matthew PC. Barnett
24. Novel Next-Generation DNA
Sequencing Techniques for Ultra 35.
High-Throughput Applications in
Bio-Medicine 365
Wilhelm I. Ansorge
25. Locus-Specific and National/Ethnic
Mutation Databases: Emerging Tools 36.
for Molecular Diagnostics 379
Cpnrep P Patrinns
Contents
Molecular Diagnostic Applications in
Forensic Science 393
Bruce Budowle, John V. Planz, Rowan
Campbell and Arthur J. Eisenberg
Mass Disaster Victim Identification
Assisted by DNA Typing 407
Daniel Corach
Detection of Highly Pathogenic
Viral Agents: Implications for
Therapeutics, Vaccines and
Biodefense 417
Kylene Kehn-Hall and Slna Bavari
Identification of Genetically
Modified Organisms 431
Farid E. Ahmed
Molecular Diagnostics and
Comparative Genomics in
Clinical Microbiology 445
Alex van Belkum
Genetic Monitoring of Laboratory
Rodents 461
jean-Louis Cuenet and Fernando J. Benavides
Safety Analysis in Retroviral
Gene Therapy: Identifying Virus
Integration Sites in
Gene-Modified Cells 471
Stephanie Laufs, Luisa Schubert, Patrick
Maier, W. lens Zeller and Stefan Fruehauf
Preimplantation Genetic
Diagnosis 485
Martine de Rycke and Karen Sermon
Automated DNA Hybridization and
Detection 501
Bert Gold
The Use of Microelectronic-Based
Techniques in Molecular Diagnostic
Assays 513
Piotr Crodzinski, Michael Ward, Robin Liu,
Kathryn Scott, Saul Surrey and Paolo Fortina
Human Gene Patents and Genetic
Testing 527
Contents
37. Genetic Counseling and Ethics in
Molecular Diagnostics 537
Mary Petrou
38. Genetic Testing and Psychology 549
Andrea Farkas Patenaude
39. General Considerations Concerning
Safety in Biomedical Research
Laboratories 563
William E. Grizzle, Walter C. Bell and
Jerry Fredenburgh
Note: The e-book for this title, including full-color images, is
40. Quality Management in the
Laboratory 573
David Burnett
Glossary 583
Index 591
available for purchase at www.elsevierdirect.com. |
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV035857325 |
| callnumber-first | R - Medicine |
| callnumber-label | RB43 |
| callnumber-raw | RB43.7 |
| callnumber-search | RB43.7 |
| callnumber-sort | RB 243.7 |
| callnumber-subject | RB - Pathology |
| classification_rvk | YV 1200 |
| ctrlnum | (OCoLC)423582260 (DE-599)HBZHT016121490 |
| dewey-full | 616.0756 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.0756 |
| dewey-search | 616.0756 |
| dewey-sort | 3616.0756 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 2. ed. |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nam a2200000 c 4500</leader><controlfield tag="001">BV035857325</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20100610</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">091202s2010 ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780123745378</subfield><subfield code="9">978-0-12-374537-8</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)423582260</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)HBZHT016121490</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-20</subfield><subfield code="a">DE-19</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RB43.7</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.0756</subfield><subfield code="2">22</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">YV 1200</subfield><subfield code="0">(DE-625)154210:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Molecular diagnostics</subfield><subfield code="c">ed. by George P. Patrinos ...</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">2. ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Amsterdam [u.a.]</subfield><subfield code="b">Elsevier, Acad. Press</subfield><subfield code="c">2010</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XVII, 598 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Molecular Diagnostic Techniques</subfield></datafield><datafield tag="650" ind1=" " ind2="2"><subfield code="a">Genetic Screening</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genetic Testing</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Genetic screening</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Molecular Diagnostic Techniques</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Molecular diagnosis</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Labormedizin</subfield><subfield code="0">(DE-588)4073931-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Molekulare Diagnostik</subfield><subfield code="0">(DE-588)4589005-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Molekulare Diagnostik</subfield><subfield code="0">(DE-588)4589005-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Labormedizin</subfield><subfield code="0">(DE-588)4073931-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Patrinos, George P.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HBZ Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018715246&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-018715246</subfield></datafield></record></collection> |
| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV035857325 |
| illustrated | Illustrated |
| indexdate | 2024-09-07T00:11:28Z |
| institution | BVB |
| isbn | 9780123745378 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018715246 |
| oclc_num | 423582260 |
| open_access_boolean | |
| owner | DE-20 DE-19 DE-BY-UBM |
| owner_facet | DE-20 DE-19 DE-BY-UBM |
| physical | XVII, 598 S. Ill., graph. Darst. |
| publishDate | 2010 |
| publishDateSearch | 2010 |
| publishDateSort | 2010 |
| publisher | Elsevier, Acad. Press |
| record_format | marc |
| spelling | Molecular diagnostics ed. by George P. Patrinos ... 2. ed. Amsterdam [u.a.] Elsevier, Acad. Press 2010 XVII, 598 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molecular Diagnostic Techniques Genetic Screening Genetic Testing Genetic screening Molecular diagnosis Labormedizin (DE-588)4073931-4 gnd rswk-swf Molekulare Diagnostik (DE-588)4589005-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Molekulare Diagnostik (DE-588)4589005-5 s DE-604 Labormedizin (DE-588)4073931-4 s Patrinos, George P. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018715246&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular diagnostics Molecular Diagnostic Techniques Genetic Screening Genetic Testing Genetic screening Molecular diagnosis Labormedizin (DE-588)4073931-4 gnd Molekulare Diagnostik (DE-588)4589005-5 gnd |
| subject_GND | (DE-588)4073931-4 (DE-588)4589005-5 (DE-588)4143413-4 |
| title | Molecular diagnostics |
| title_auth | Molecular diagnostics |
| title_exact_search | Molecular diagnostics |
| title_full | Molecular diagnostics ed. by George P. Patrinos ... |
| title_fullStr | Molecular diagnostics ed. by George P. Patrinos ... |
| title_full_unstemmed | Molecular diagnostics ed. by George P. Patrinos ... |
| title_short | Molecular diagnostics |
| title_sort | molecular diagnostics |
| topic | Molecular Diagnostic Techniques Genetic Screening Genetic Testing Genetic screening Molecular diagnosis Labormedizin (DE-588)4073931-4 gnd Molekulare Diagnostik (DE-588)4589005-5 gnd |
| topic_facet | Molecular Diagnostic Techniques Genetic Screening Genetic Testing Genetic screening Molecular diagnosis Labormedizin Molekulare Diagnostik Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018715246&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT patrinosgeorgep moleculardiagnostics |