Tissue engineering using ceramics and polymers:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boca Raton [u.a.]
CRC Press
2007
Cambridge Woodhead Publ. |
| Ausgabe: | 1. publ. |
| Schriftenreihe: | Woodhead Publishing in materials
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | "Woodhead Publishing and Maney Publishing on behalf of the Institute of Materials, Minerals & Mining." Includes bibliographical references and index |
| Beschreibung: | xx, 604 p. Ill., graph. Darst. |
| ISBN: | 9781420044546 9781845691769 |
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| 650 | 4 | |a Ceramics | |
| 650 | 4 | |a Polymers | |
| 650 | 4 | |a Biocompatible Materials | |
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| 650 | 4 | |a Tissue engineering | |
| 650 | 4 | |a Organ culture | |
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| 650 | 4 | |a Polymers in medicine | |
| 650 | 4 | |a Génie tissulaire | |
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| 650 | 4 | |a Biocompatible Materials | |
| 650 | 4 | |a Ceramics | |
| 650 | 4 | |a Ceramics in medicine | |
| 650 | 4 | |a Organ culture | |
| 650 | 4 | |a Polymers | |
| 650 | 4 | |a Polymers in medicine | |
| 650 | 4 | |a Tissue Engineering | |
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Datensatz im Suchindex
| _version_ | 1814366584466046976 |
|---|---|
| adam_text |
Contents
Contributor contact details xiii
Introduction xix
Part I General issues
1 Ceramic biomaterials 3
J Huang, University College London, UK and
S M BE S T, University of Cambridge, UK
1.1 Introduction 3
1.2 Characteristics of ceramics 9
1.3 Microstructure of ceramics 12
1.4 Properties of ceramics 16
1.5 Processing of ceramics 22
1.6 Conclusions 26
1.7 Future trends 26
1.8 References 27
2 Polymeric biomaterials 32
G Wei and P X Ma, The University of Michigan, USA
2.1 Introduction 32
2.2 Polymeric scaffolds for tissue engineering 33
2.3 Polymeric scaffolds with controlled release capacity 43
2.4 Conclusions 47
2.5 References 47
3 Bioactive ceramics and glasses 52
J R Jo N E S, Imperial College, London, UK
3.1 Introduction 52
3.2 Synthetic hydroxyapatite 54
3.3 Bioactive glass 58
vi Contents
3.4 Glass-ceramics 67
3.5 Conclusions 67
3.6 References 68
4 Biodegradable and bioactive polymer/ceramic
composite scaffolds 72
S K MiSRA and A R Boccaccini, Imperial College
London, UK
4.1 Introduction 72
4.2 Biodegradable polymers and bioactive ceramics 74
4.3 Composite material approach 78
4.4 Materials processing strategies for composite scaffolds 80
4.5 Case studies 83
4.6 Conclusions and future trends 87
4.7 References and further reading 89
5 Transplantation of engineered cells and tissues 93
J MANSBRIDGE, Tecellact LLC, USA
5.1 Introduction 93
5.2 Rejection of tissue-engineered products 95
5.3 Testing and regulatory consequences 102
5.4 Generality of the resistance of tissue-engineered products to
immune rejection 102
5.5 Manufacturing consequences 103
5.6 Conclusions and future trends 104
5.7 Sources of further information and advice 105
5.8 Acknowledgements 105
5.9 References 105
6 Surface modification to tailor the biological
response 108
K Shakesheff and G Tsourpas, University of
j Nottingham, UK
6.1 Introduction 108
6.2 The biochemistry of cell interactions with the ECM 108
6.3 The need for surface modification of scaffolds 114
6.4 General strategies for surface modification 115
6.5 Examples from the literature 116
6.6 Future trends 123
6.7 References 124
Contents vii
7 Combining tissue engineering and drug delivery 129
N TlRELLi and F CELL ESI, University of Manchester, UK
7.1 Introduction 129
7.2 Growth factor (GF) delivery 131
7.3 Signalling molecules in solution (parenteral administration) 135
7.4 Signalling molecules physically entrapped in a matrix 136
7.5 Signalling molecules released from a bound state 147
7.6 References 149
8 Carrier systems and biosensors for biomedical
applications 153
F Davis and S P J HiGson, Cranfield University, UK
8.1 Introduction 153
8.2 Carrier systems 153
8.3 Commercial systems 161
8.4 Biosensors 162
8.5 Continuous monitoring 167
8.6 Future trends 169
8.7 Conclusions 170
8.8 References 171
9 Characterisation using X-ray photoelectron
spectroscopy (XPS) and secondary ion
mass spectrometry (SIMS) 175
AJUrquhart and M R Alexander, University of
Nottingham, UK
9.1 Introduction 175
9.2 X-ray photoelectron spectroscopy (XPS) 177
9.3 Static secondary ion mass spectrometry (SIMS) 187
9.4 Specific sample preparation and acquisition procedures 193
9.5 Conclusions 197
9.6 Future trends 198
9.7 Acknowledgement 199
9.8 References 199
10 Characterisation using environmental scanning
electron microscopy (ESEM) 204
A M Do N A L D, University of Cambridge, UK
10.1 Introduction 204
10.2 The instrument: a comparison with CSEM 204
10.3 Static experiments 210
10.4 Dynamic experiments 212
viii Contents
10.5 Dual beam instruments - an emerging technique 218
10.6 Potential and limitations 219
10.7 Conclusions 221
10.8 References 221
11 Characterisation of cells on tissue engineered
construsts using imaging techniques/microscopy 226
SIAnderson, University of Nottingham, UK
11.1 Introduction 226
11.2 General considerations and experimental design 226
11.3 CLSM 228
11.4 Combining techniques 241
11.5 Future trends 244
11.6 References 245
12 Characterisation using Raman micro-spectroscopy 248
INotingher, University of Nottingham, UK
12.1 Introduction 248
12.2 Principles of Raman spectroscopy 251
12.3 Characterisation of living cells 254
12.4 Characterisation of tissue engineering scaffolds 259
12.5 Conclusions and future trends 263
12.6 References 264
Part II Tissue and organ generation
13 Engineering of tissues and organs 269
A Atala, Wake Forest University, USA
13.1 Introduction 269
13.2 Native cells 270
13.3 Biomaterials 271
13.4 Alternate cell sources: stem cells and nuclear transfer 273
13.5 Tissue engineering of specific structures 277
13.6 Cellular therapies 284
13.6 Conclusions and future trends 288
13.7 References 289
Contents ix
14 Bone regeneration and repair using tissue
engineering 294
P WOZNIAK, Medical University of Warsaw, Poland and
A J EL Haj, Keele University Medical School, UK
14.1 Introduction 294
14.2 Principles of bone biology 294
14.3 Basics of bone remodelling 299
14.4 Skeletal tissue reconstruction - a tissue engineering approach 304
14.5 Conclusions 314
14.6 Acknowledgements 315
14.7 References 315
15 Bone tissue engineering and biomineralization 319
L Di Silvio, Kings College London, UK
15.1 Introduction 319
15.2 Tissue engineering 320
15.3 Scaffolds and biomineralization 327
15.4 Conclusions and future trends 330
15.5 References 331
16 Cardiac tissue engineering 335
QZCHEN,SEHARDlNG,NNALl,HJAWADand
ARBOCCACCINI, Imperial College London, UK
16.1 Introduction 335
16.2 Cell sources 336
16.3 Construct-based strategies in myocardial tissue engineering 343
16.4 Conclusions and future trends 350
16.5 Acknowledgement 352
16.6 References and further reading 352
17 Intervertebral disc tissue engineering 357
J Ho Y L A N D and T FREEMONT, University of Manchester,
UK
17.1 Introduction 357
17.2 The impact of disorders of the intervertebral disc (IVD) on
modern society 357
17.3 The normal anatomy, function and cell biology of the IVD 358
17.4 The pathobiology of IVD degeneration 359
17.5 Treatment of degeneration of the IVD 364
17.6 The place of biomaterials in proposed strategies for managing
IVD degeneration 366
17.7 Tissue regeneration and the IVD 371
x Contents
17.8 Conclusions 372
17.9 Future trends 373
17.10 Sources of further information and advice 374
17.11 References 375
18 Skin tissue engineering 379
S Ma c Ne i l , University of Sheffield, UK
18.1 Why do we need tissue-engineered skin? 379
18.2 Key events in the development of tissue-engineered skin 383
18.3 Do we need stem cells for tissue engineering of skin? 385
18.4 Key steps in development of tissue-engineered skin for
clinical use 385
18.5 Challenges in converting research into products 386
18.6 Clinical problems in the use of tissue-engineered skin 391
18.7 Unexpected results from using 3D skin models 396
18.8 Future trends 398
18.9 References 399
19 Liver tissue engineering 404
K Shakesheff, University of Nottingham, UK
19.1 Introduction 404
19.2 The structure of the liver lobule 405
19.3 Clinical and commercial applications of engineered liver tissue 405
19.4 Approaches to liver tissue engineering 407
19.5 Conclusions 415
19.6 Future trends 416
19.7 References 416
20 Kidney tissue engineering 421
A SAIT O, Tokai University, Japan
20.1 Introduction 421
20.2 Present status of kidney regeneration 421
20.3 Functional limitation of current haemodialysis as an artificial
kidney 423
20.4 System configuration for bioartificial kidneys 423
20.5 Past and current status of development of bioartificial kidneys 426
20.6 Attachment and proliferation of tubular epithelial cells on
polymer membranes 429
20.7 Function of tubular epithelial cells on polymer membranes 433
20.8 Evaluation of a long-term function of LLC-PK[ cell-attached
hollow fibre membrane 435
20.9 Improvement of the components of a portable bioartificial
kidney developed for long-term use 438
Contents xi
20.10 Conclusions and future trends 441
20.11 References 442
21 Bladder tissue engineering 445
A M Turner, University of York, UK, R Subramaniam
and D F M Thomas, St. James's University Hospital, UK,
and JSOUTHGATE, University of York, UK
21.1 The bladder - structure and function 445
21.2 The clinical need for bladder reconstruction 447
21.3 Concepts and strategies of bladder reconstruction and tissue
engineering 448
21.4 Review of past and current strategies in bladder reconstruction 449
21.5 Cell conditioning in an external bioreactor 457
21.6 Future trends 458
21.7 Conclusions 459
21.8 References 459
22 Nerve bioengineering 466
P Kl N G H A M and G Te R E N G HI, University of Manchester, UK
22.1 Peripheral nerve 466
22.2 Peripheral nerve injury and regeneration 468
22.3 Peripheral nerve repair 468
22.4 Bioengineered nerve conduits 469
22.5 Matrix materials 473
22.6 Cultured cells and nerve constructions 476
22.7 Conclusions 484
22.8 References 484
23 Lung tissue engineering 497
A E Bishop and H J Rippon, Imperial College London, UK
23.1 Introduction 497
23.2 Lung structure 497
23.3 Sources of cells for lung tissue engineering 499
23.4 Lung tissue constructs 501
23.5 Conclusions 505
23.6 References 505
24 Intestine tissue engineering 508
D A J Lloyd and S M Gabe, St Mark's Hospital, UK
24.1 Introduction 508
24.2 Approaches to tissue engineering of the small intestine 508
24.3 Artificial scaffolds 510
xii Contents
24.4 Intestinal lengthening using artificial scaffolds 514
24.5 Transplantation of intestinal stem cell cultures 516
24.6 Growth factors 523
24.7 Future trends 524
24.8 Conclusions 525
24.9 References 525
25 Micromechanics of hydroxyapatite-based
biomaterials and tissue engineering scaffolds 529
A Fritsch and L Dormieux, Ecole Nationale des Ponts
et Chaussees (LMSGC-ENPC), France, C He l l m I c H, Vienna
University of Technology, Austria and J Sanahuja, Lafarge
Research Center, France
25.1 Introduction 529
25.2 Fundamentals of continuum micromechanics 535
25.3 Micromechanical representation of mono-porosity biomaterials
made of hydroxyapatite - stiffness and strength estimates 538
25.4 Model validation 542
25.5 Continuum micromechanics model for 'hierarchical'
hydroxyapatite biomaterials with two pore spaces used for
tissue engineering 551
25.6 Conclusions and future trends 557
25.7 Appendix: Homothetic ('cone-type') shape of failure criterion
for hydroxyapatite biomaterials - Drucker-Prager approximation 558
25.8 Nomenclature 559
25.9 References 563
26 Cartilage tissue engineering 566
J E GouGH, University of Manchester, UK
26.1 Introduction 566
26.2 Structure, cellularity and extracellular matrix 566
26.3 The need for cartilage repair 567
26.4 Current treatments including autologous chondrocyte
transplantation 568
26.5 Cell source 569
26.6 Materials 570
26.7 Growth factors and oxygen 576
26.8 Loading 579
26.9 Osteochondral defects 580
26.10 Conclusions and future trends 580
26.11 References 581
Index 587 |
| any_adam_object | 1 |
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| bvnumber | BV035848865 |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1. publ. |
| format | Book |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV035848865 |
| illustrated | Illustrated |
| indexdate | 2024-10-30T19:00:12Z |
| institution | BVB |
| isbn | 9781420044546 9781845691769 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018706975 |
| oclc_num | 213379338 |
| open_access_boolean | |
| owner | DE-29 DE-29T |
| owner_facet | DE-29 DE-29T |
| physical | xx, 604 p. Ill., graph. Darst. |
| publishDate | 2007 |
| publishDateSearch | 2007 |
| publishDateSort | 2007 |
| publisher | CRC Press Woodhead Publ. |
| record_format | marc |
| series2 | Woodhead Publishing in materials |
| spelling | Tissue engineering using ceramics and polymers edited by Aldo R. Boccaccini and Julie E. Gough 1. publ. Boca Raton [u.a.] CRC Press 2007 Cambridge Woodhead Publ. xx, 604 p. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Woodhead Publishing in materials "Woodhead Publishing and Maney Publishing on behalf of the Institute of Materials, Minerals & Mining." Includes bibliographical references and index Ceramics Polymers Biocompatible Materials Tissue Engineering Tissue engineering Organ culture Ceramics in medicine Polymers in medicine Génie tissulaire Organes / Culture Céramique en médecine Polymères en médecine Organes - Culture Biomedizinische Technik (DE-588)4006882-1 gnd rswk-swf Biokeramik (DE-588)4371693-3 gnd rswk-swf Tissue Engineering (DE-588)4646061-5 gnd rswk-swf Biopolymere (DE-588)4006893-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Tissue Engineering (DE-588)4646061-5 s Biokeramik (DE-588)4371693-3 s DE-604 Biopolymere (DE-588)4006893-6 s Biomedizinische Technik (DE-588)4006882-1 s Boccaccini, Aldo R. 1962- Sonstige (DE-588)13022362X oth Erscheint auch als Online-Ausgabe 978-1-84569-381-7 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018706975&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Tissue engineering using ceramics and polymers Ceramics Polymers Biocompatible Materials Tissue Engineering Tissue engineering Organ culture Ceramics in medicine Polymers in medicine Génie tissulaire Organes / Culture Céramique en médecine Polymères en médecine Organes - Culture Biomedizinische Technik (DE-588)4006882-1 gnd Biokeramik (DE-588)4371693-3 gnd Tissue Engineering (DE-588)4646061-5 gnd Biopolymere (DE-588)4006893-6 gnd |
| subject_GND | (DE-588)4006882-1 (DE-588)4371693-3 (DE-588)4646061-5 (DE-588)4006893-6 (DE-588)4143413-4 |
| title | Tissue engineering using ceramics and polymers |
| title_auth | Tissue engineering using ceramics and polymers |
| title_exact_search | Tissue engineering using ceramics and polymers |
| title_full | Tissue engineering using ceramics and polymers edited by Aldo R. Boccaccini and Julie E. Gough |
| title_fullStr | Tissue engineering using ceramics and polymers edited by Aldo R. Boccaccini and Julie E. Gough |
| title_full_unstemmed | Tissue engineering using ceramics and polymers edited by Aldo R. Boccaccini and Julie E. Gough |
| title_short | Tissue engineering using ceramics and polymers |
| title_sort | tissue engineering using ceramics and polymers |
| topic | Ceramics Polymers Biocompatible Materials Tissue Engineering Tissue engineering Organ culture Ceramics in medicine Polymers in medicine Génie tissulaire Organes / Culture Céramique en médecine Polymères en médecine Organes - Culture Biomedizinische Technik (DE-588)4006882-1 gnd Biokeramik (DE-588)4371693-3 gnd Tissue Engineering (DE-588)4646061-5 gnd Biopolymere (DE-588)4006893-6 gnd |
| topic_facet | Ceramics Polymers Biocompatible Materials Tissue Engineering Tissue engineering Organ culture Ceramics in medicine Polymers in medicine Génie tissulaire Organes / Culture Céramique en médecine Polymères en médecine Organes - Culture Biomedizinische Technik Biokeramik Biopolymere Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018706975&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT boccaccinialdor tissueengineeringusingceramicsandpolymers |