Genetic dissection of neural circuits and behavior:
Gespeichert in:
Weitere Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2009
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Ausgabe: | 1. ed. |
Schriftenreihe: | Advances in genetics
65 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Einzelaufnahme eines Zeitschr.-Bd. |
Beschreibung: | VII, 199 S. Ill., graph. Darst. |
ISBN: | 9780123748362 |
Internformat
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245 | 1 | 0 | |a Genetic dissection of neural circuits and behavior |c ed. by Stephen F. Goodwin |
250 | |a 1. ed. | ||
264 | 1 | |a Amsterdam [u.a.] |b Elsevier |c 2009 | |
300 | |a VII, 199 S. |b Ill., graph. Darst. | ||
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999 | |a oai:aleph.bib-bvb.de:BVB01-018680990 |
Datensatz im Suchindex
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adam_text | Titel: Genetic dissection of neural circuits and behavior
Autor: Goodwin, Stephen F.
Jahr: 2009
Contents
Contributors vii
1 Genetic Dissection of Neural Circuits and Behavior
in Mus musculus 1
Robbert Havekes and Ted Abel
I. Conventional Gene Targeting Strategies 2
II. Spatially Restricted Gene Manipulation 5
III. The Use of Dominant Negative Inhibitors
to Manipulate Gene Function 10
IV. Conditional Manipulation of Gene Function 11
V. Pharmacogenetic Approaches 16
VI. Optogenetic Approaches 22
VII. Visualization of Brain Structure and Function 24
VIII. The Challenges Facing Genetic Approaches in
the Mouse 28
References 32
2 Worm Watching: Imaging Nervous System Structure
and Function in Caenorhabditis elegans 39
Jeremy Dittman
I. Introduction 40
II. Real-Time Indicators of Neuronal Activity 43
III. Monitoring Intracellular Calcium 45
IV. Imaging Presynaptic Terminals 49
V. Imaging Postsynaptic Compartments 54
VI. Imaging Proxies for Neuropeptide Secretion 58
VII. Bimolecular Fluorescence Complementation
in the Worm 60
VIII. Methods for Immobilizing the Worm 61
IX. Femtosecond Lasers and Nanosurgery
on the Worm 65
X. Designing the Ideal Optical Probe 67
XI. Conclusions and Prospects 70
References 70
vi Contents
3 Mapping and Manipulating Neural Circuits
in the Fly Brain 79
Julie H. Simpson
I. Introduction 80
II. Spatial Targeting of Neuron Types 86
III. Imaging Neurons 92
IV. Functional Imaging: Watching Neuronal Activity 95
V. Control of Neural Activity 100
VI. Quantitative Behavioral Assays 113
VII. Conclusions 118
References 121
4 A Network of G-Protein Signaling Pathways Control
Neuronal Activity in C. elegans 145
Borja Perez-Mansilla and Stephen Nurrish
I. Introduction 146
II. Mapping Intracellular Neural Networks within
C. elegans Motorneurons 151
References 178
Index 193
Color Plate Section at the end of the Book
|
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illustrated | Illustrated |
indexdate | 2024-07-09T22:05:24Z |
institution | BVB |
isbn | 9780123748362 |
language | English |
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physical | VII, 199 S. Ill., graph. Darst. |
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series2 | Advances in genetics |
spelling | Genetic dissection of neural circuits and behavior ed. by Stephen F. Goodwin 1. ed. Amsterdam [u.a.] Elsevier 2009 VII, 199 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advances in genetics 65 Einzelaufnahme eines Zeitschr.-Bd. DNA-onderzoek gtt Zenuwstelsel gtt Goodwin, Stephen F. edt HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018680990&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Genetic dissection of neural circuits and behavior DNA-onderzoek gtt Zenuwstelsel gtt |
title | Genetic dissection of neural circuits and behavior |
title_auth | Genetic dissection of neural circuits and behavior |
title_exact_search | Genetic dissection of neural circuits and behavior |
title_full | Genetic dissection of neural circuits and behavior ed. by Stephen F. Goodwin |
title_fullStr | Genetic dissection of neural circuits and behavior ed. by Stephen F. Goodwin |
title_full_unstemmed | Genetic dissection of neural circuits and behavior ed. by Stephen F. Goodwin |
title_short | Genetic dissection of neural circuits and behavior |
title_sort | genetic dissection of neural circuits and behavior |
topic | DNA-onderzoek gtt Zenuwstelsel gtt |
topic_facet | DNA-onderzoek Zenuwstelsel |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018680990&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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