Biomembrane frontiers: nanostructures, models, and the design of life
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Humana Press
2009
|
| Schriftenreihe: | Handbook of modern biophysics
2 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XXII, 323 S. ill. 27 cm |
| ISBN: | 9781607613138 |
Internformat
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| 245 | 1 | 0 | |a Biomembrane frontiers |b nanostructures, models, and the design of life |c Roland Faller ... [et al.], editors |
| 264 | 1 | |a New York, NY |b Humana Press |c 2009 | |
| 300 | |a XXII, 323 S. |b ill. |c 27 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Handbook of modern biophysics |v 2 | |
| 650 | 4 | |a Lipoproteins |v Congresses | |
| 650 | 4 | |a Membrane Lipids |v Congresses | |
| 650 | 4 | |a Membrane Proteins |v Congresses | |
| 650 | 4 | |a Membranes (Biology) | |
| 650 | 4 | |a Membranes |v Congresses | |
| 650 | 4 | |a Nanostructures |v Congresses | |
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Datensatz im Suchindex
| _version_ | 1804140723099926528 |
|---|---|
| adam_text | Contents
Perspectives: Complexes in Liquids,
1900-2008
Harden McConnell
Introduction
.....................................................................................................................................
xv¡j
Complexes and the Origin of Liquid-Liquid Immiscibility
............................................................ xvii
Outlook
...........................................................................................................................................
xxj
1
Molecular Theory Applied to
Lipid
Bilayers and
Lipid-Protein Interactions
Amálie L
Frischknecht
and Laura
J. D. Frink
1.1.
Introduction
......................................................................................................................... 1
1.2.
Essential Elements for Molecular Membrane Theories
....................................................... 3
1.3.
Fluids Density Functional Theories
..................................................................................... 6
1.4.
A Simple
Lipid
Model
......................................................................................................... 14
1.5.
Performing Fluids-DFT Calculations for Model
Lipid
Bilayers
......................................... 16
1.6.
Lipid
Bilayer Structure
........................................................................................................ 17
1.7.
Mechanical Properties of Bilayers
....................................................................................... 29
1.8.
Conclusions
......................................................................................................................... 34
2
Membrane Elasticity and Mediated Interactions in
Continuum Theory: A Differential Geometric Approach
Markus Desemo
2.1.
Introduction: Biophysics and Scale Separation
................................................................... 41
2.2.
Continuum Theory for Membranes: A First Look
............................................................... 43
2.3.
Curvature Elasticity
............................................................................................................. 47
2.4.
Membrane Stresses and Shape Equilibria
............................................................................ 53
2.5.
Membrane-Mediated Interactions
........................................................................................ 59
2.6.
Summary
............................................................................................................................. 68
vii
viii
CONTENTS
3
Structure and Dynamics of
Lipid
Monolayers:
Theory and Applications
Svetlana
Baoukina, Siewert J. Marrink, and D. Peter Tieleman
3.1.
Introduction
......................................................................................................................... 75
3.2.
Lipid
Monolayers: Basic Properties and Applications
........................................................ 76
3.3.
Experimental Studies
........................................................................................................... 83
3.4.
Theoretical Models
.............................................................................................................. 85
3.5.
Computer Simulations
......................................................................................................... 86
3.6.
Conclusions and Outlook
.................................................................................................... 95
4
Multiscale Modeling of Supported
Lipid
Bilayers
Matthew I. Hoopes, Chenyue Xing, and Roland
Faller
4.1.
Introduction
......................................................................................................................... 101
4.2.
Multiscale Modeling of Membranes
.................................................................................... 102
4.3.
Atomistic Modeling
............................................................................................................. 104
4.4.
Mesoscale Modeling
............................................................................................................ 105
4.5.
Water-Free Large-Scale Modeling
...................................................................................... 106
4.6.
Visualizations
...................................................................................................................... 107
4.7.
Density Profiles
................................................................................................................... 107
4.8.
Pressure and Lateral Tension
............................................................................................... 113
4.9.
Summary and Outlook
......................................................................................................... 115
Collective Dynamics in
Lipid
Membranes:
From Pore Formation to Flip-Flops
Andrey
A. Gurtovenko and
Про
Vattulainen
5.1.
Introduction
......................................................................................................................... 121
5.2.
Dynamics of Lipids in Membranes
..................................................................................... 122
5.3.
Flip-Flops Associated with Asymmetric Distribution of Lipids in Membranes
.................. 123
5.4.
Formation of Transient Water Pores in
Lipid
Membranes
.................................................. 124
5.5.
Flip-Flops of
Lipid
Molecules across Protein-Free
Lipid
Membranes
................................ 129
5.6.
Summary
............................................................................................................................. 135
HANDBOOK OF MODERN BIOPHYSICS, volume
2
¡x
6
Spatiotemporal
Organization of Spin-Coated Supported
Model Membranes
Adam Cohen
Simonsen
6.1.
Introduction
......................................................................................................................... 141
6.2.
Methods for Preparing Supported Membranes
.................................................................... 142
6.3.
Membrane Support Materials
.............................................................................................. 144
6.4.
Spin Coating
........................................................................................................................ 146
6.5.
Lamellar
Lipid
Films by Spin Coating
................................................................................ 147
6.6.
Supported Membranes by
Hydration
of Spin-Coated Precursor Films
............................... 150
6.7.
Membrane Support and Membrane-Membrane Interactions
.............................................. 151
6.8.
Imaging the Membrane
Microstructure
............................................................................... 153
6.9.
AFM for Imaging Supported Membranes
........................................................................... 154
6.10.
Fluorescence Microscopy for Imaging Supported Membranes
........................................... 157
6.11.
Phase Transitions and Domains in Model Membranes
....................................................... 159
6.12.
Binary Model Membranes
................................................................................................... 161
6.13.
Ternary Model Membranes
................................................................................................. 162
Appendix
......................................................................................................................................... 169
7
Nanopore Analysis of Nucleic Acids: Single-Molecule
Studies of Molecular Dynamics, Structure, and Base Sequence
Felix Olasagasti and David W. Deamer
7.1.
Introduction
......................................................................................................................... 171
7.2.
The Nanopore Apparatus
..................................................................................................... 172
7.3.
Detection of Single Macromolecules
................................................................................... 173
7.4.
Detection of Macromolecular Complexes
........................................................................... 180
7.5.
Conclusions and Future Prospects
....................................................................................... 183
8
Complex Applications of Simple FRAP on Membranes
Minchul Kong and
Anne K.
Kenworthy
8.1.
Introduction
......................................................................................................................... ^7
8.2.
Principles of Fluorescence
................................................................................................... 188
8.3.
Basic Theory of FRAP
........................................................................................................
197
8.4.
Further Applications of FRAP
.............................................................................................
205
8.5.
Challenges and Artifacts in Confocal FRAP
....................................................................... 215
8.6.
Summary
............................................................................................................................. 217
CONTENTS
Punching Holes in Membranes: How Oligomeric
Pore-Forming Proteins and Lipids Cooperate to
Form Aqueous Channels in Membranes
Cécile
Fradin,
Dmitri Satsoura, and David W. Andrews
9.1.
Introduction
........................................................................................................................ 223
9.2.
Pore-Forming Proteins
....................................................................................................... 224
9.3.
Pore Structures
................................................................................................................... 233
9.4.
Influence of the Lipids on Pore Formation and Stability
................................................... 241
9.5.
Pore Formation Mechanism
............................................................................................... 246
9.6.
Summary
............................................................................................................................ 250
10
Morphogens,
Membranes and Mechanotransduction
in Articular Cartilage
Shirley Motaung, Stephanie Chan, and A. Hari Reddi
10.1.
Introduction
........................................................................................................................ 263
10.2.
Morphogens
....................................................................................................................... 263
10.3.
Cartilage Morphogenesis
................................................................................................... 264
10.4.
Bone Morphogenetic Proteins
............................................................................................ 264
10.5.
Structure and Function of Articular Cartilage
.................................................................... 265
10.6.
Role of Transforming Growth Factor
(TGF
-β)
in Chondrocytes
....................................... 265
10.7.
Membranes and Matrix in Mechanotransduction
............................................................... 266
10.8.
Mechanical Properties of Cartilage
.................................................................................... 267
10.9.
Mechanical Signal Transduction
........................................................................................ 268
10.10.
Applications of BMPs
........................................................................................................ 270
10.11.
Summary
............................................................................................................................ 270
11
Lifecycle of a Lipoprotein from a Biophysical Perspective
John C. Rut ledge, Thomas Huser, John
Voss,
James Chan, andAtul Parikh
11.1.
Introduction
........................................................................................................................ 275
11.2.
Laser Trapping Raman Spectroscopy for Analysis of Single Lipoproteins
....................... 276
11.3.
Apolipoprotein
E
Conformation^ Changes in the Postprandial State
............................... 278
11.4.
TGRL Lipolysis Products and Vascular Inflammation
...................................................... 279
11.5.
Cell-Free Membrane-Mimetic Model Bilayers to Study Interaction of
TGRL with Raft-Like
Microenvironments........................................................................ 280
11.6.
TGRL Lipolysis Products and Increased Endothelial Layer Permeability
......................... 280
11.7.
Monocytes and TGRL Lipolysis Products
......................................................................... 280
11.8.
Summary
............................................................................................................................ 282
11.9.
Conclusions
........................................................................................................................ 282
HANDBOOK OF MODERN BIOPHYSICS, volume
2
x¡
12
Targeting Apolipoproteins in Magnetic Resonance Imaging
Renuka Sriram, Jens O.
Lagerstedt, Haris Samardzic,
Ulrike
Kreutzer,
Jitka
Petrolova, Hongtao Xie, George A. Kaysen, John
С
Voss,
Jean
F. Desreux, and Thomas Jue
12.1.
Introduction
........................................................................................................................ 285
12.2. Chylomicrons and Triacylglycerol..................................................................................... 286
12.3. LDL
and Cholesterol
Transport......................................................................................... 286
12.4.
HDL and Cholesterol Scavenging......................................................................................
287
12.5. Lipoproteins
as Indices of CVD Risk
................................................................................ 288
12.6.
Apolipoproteins and CVD Risk
......................................................................................... 288
12.7.
ApoA-IandHDL
............................................................................................................... 289
12.8.
ApoA-I Therapy
................................................................................................................. 289
12.9.
Imaging Lipoprotein In Vivo
............................................................................................. 290
12.10.
Specific apoA-I Contrast Agent
......................................................................................... 290
12.11.
Relaxivity
........................................................................................................................... 291
12.12.
Imaging apoA-I in Vivo
..................................................................................................... 293
12.13.
Summary
............................................................................................................................ 293
Problem Solutions
...................................................................................................... 299
Index
............................................................................................................................ 317
Handbook of Modern Biophysics
Series Editor: Thomas Jue, PhD
Handbook of Modern Biophysics brings current biophysics topics into focus, so that biology, medical,
engineering, mathematics, and physical-science students or researchers can learn fundamental
concepts and the application of new techniques in addressing
biomedical
challenges. Chapters
explicate the conceptual framework of the physics formalism and illustrate the
biomedical
applications. With the addition of problem sets, guides to further study, and references, the interested
reader can continue to explore independently the ideas presented.
Biomembrane
Frontiers: Nanostructures, Models, and the Design of Life
Volume
2
Edited by
Roland
Faller,
pnd, Thomas Jue, Pho, Marjorie L.
Longo,
PhD, and Subhash H. Risbud,
рьо
In
Biomembrane
Frontiers: Nanostructures, Models, and the Design of Life,
prominent researchers have established a foundation for the study of biophysics
related to the following topics:
•
Perspectives: Complexes in Liquids,
1900-2008
•
Molecular Theory Applied to
Lipid Bilayers
and Lipid-Protein Interactions
•
Membrane Elasticity and Mediated Interactions in Continuum Theory
•
Structure and Dynamics of
Lipid
Monolayers
•
Multiscale Modeling of Supported
Lipid
Bilayers
•
Collective Dynamics in
Lipid
Membranes
•
Spatiotemporal
Organization of Spin-Coated Supported Model Membranes
•
Nanopore Analysis of Nucleic Acids
•
Complex Applications of Simple FRAP on Membranes
•
Punching Holes in Membranes
•
Morphogens,
Membranes and Mechanotransduction in Articular Cartilage
•
Lifecycle of a Lipoprotein from a Biophysical Perspective
•
Targeting Apolipoproteins in Magnetic Resonance Imaging
|
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| genre | (DE-588)1071861417 Konferenzschrift gnd-content |
| genre_facet | Konferenzschrift |
| id | DE-604.BV035785303 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:04:30Z |
| institution | BVB |
| isbn | 9781607613138 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018644741 |
| oclc_num | 430495946 |
| open_access_boolean | |
| owner | DE-703 DE-11 |
| owner_facet | DE-703 DE-11 |
| physical | XXII, 323 S. ill. 27 cm |
| publishDate | 2009 |
| publishDateSearch | 2009 |
| publishDateSort | 2009 |
| publisher | Humana Press |
| record_format | marc |
| series | Handbook of modern biophysics |
| series2 | Handbook of modern biophysics |
| spelling | Biomembrane frontiers nanostructures, models, and the design of life Roland Faller ... [et al.], editors New York, NY Humana Press 2009 XXII, 323 S. ill. 27 cm txt rdacontent n rdamedia nc rdacarrier Handbook of modern biophysics 2 Lipoproteins Congresses Membrane Lipids Congresses Membrane Proteins Congresses Membranes (Biology) Membranes Congresses Nanostructures Congresses Biomembran (DE-588)4006884-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift gnd-content Biomembran (DE-588)4006884-5 s DE-604 Faller, Roland 1972- Sonstige (DE-588)12235205X oth Erscheint auch als Online-Ausgabe 978-1-60761-314-5 Handbook of modern biophysics 2 (DE-604)BV035808474 2 Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018644741&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018644741&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Biomembrane frontiers nanostructures, models, and the design of life Handbook of modern biophysics Lipoproteins Congresses Membrane Lipids Congresses Membrane Proteins Congresses Membranes (Biology) Membranes Congresses Nanostructures Congresses Biomembran (DE-588)4006884-5 gnd |
| subject_GND | (DE-588)4006884-5 (DE-588)1071861417 |
| title | Biomembrane frontiers nanostructures, models, and the design of life |
| title_auth | Biomembrane frontiers nanostructures, models, and the design of life |
| title_exact_search | Biomembrane frontiers nanostructures, models, and the design of life |
| title_full | Biomembrane frontiers nanostructures, models, and the design of life Roland Faller ... [et al.], editors |
| title_fullStr | Biomembrane frontiers nanostructures, models, and the design of life Roland Faller ... [et al.], editors |
| title_full_unstemmed | Biomembrane frontiers nanostructures, models, and the design of life Roland Faller ... [et al.], editors |
| title_short | Biomembrane frontiers |
| title_sort | biomembrane frontiers nanostructures models and the design of life |
| title_sub | nanostructures, models, and the design of life |
| topic | Lipoproteins Congresses Membrane Lipids Congresses Membrane Proteins Congresses Membranes (Biology) Membranes Congresses Nanostructures Congresses Biomembran (DE-588)4006884-5 gnd |
| topic_facet | Lipoproteins Congresses Membrane Lipids Congresses Membrane Proteins Congresses Membranes (Biology) Membranes Congresses Nanostructures Congresses Biomembran Konferenzschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018644741&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018644741&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV035808474 |
| work_keys_str_mv | AT fallerroland biomembranefrontiersnanostructuresmodelsandthedesignoflife |