High throughput screening: methods and protocols
Gespeichert in:
Bibliographische Detailangaben
Format: Buch
Sprache:English
Veröffentlicht: Dordrecht [u.a.] Humana Press 2009
Ausgabe:2. ed
Schriftenreihe:Methods in molecular biology 565
Schlagworte:
Beschreibung:Includes bibliographical references and index
1. Design and Implementation of High-Throughput Screening Assays / Ricardo Macarron and Robert P. Hertzberg -- 2 Creation of a Small High-Throughput Screening Facility / Tod Flak -- 3 Informatics in Compound Library Management / Mark Warne and Louise Pemberton -- 4 Statistics and Decision Making in High-Throughput Screening / Isabel Coma, Jesus Herranz, and Julio Martin -- 5 Enzyme Assay Design for High-Throughput Screening / Kevin P. Williams and John E. Scott -- 6 Application of Fluorescence Polarization in HTS Assays / Xinyi Huang and Ann Aulabaugh -- 7 Screening G Protein-Coupled Receptors: Measurement of Intracellular Calcium Using the Fluorometric Imaging Plate Reader / Renee Emkey and Nancy B. Rankl -- 8 High-Throughput Automated Confocal Microscopy Imaging Screen of a Kinase-Focused Library to Identify p38 Mitogen-Activated Protein Kinase Inhibitors Using the GE InCell 3000 Analyzer. / O. Joseph Trask, Debra Nickischer, Audrey Burton, Rhonda Gates Williams, Ramani A. Kandasamy, Patricia A. Johnston, and Paul A. Johnston -- 9 Recent Advances in Electrophysiology-Based Screening Technology and the Impact upon Ion Channel Discovery Research / Andrew Southan and Gary Clark -- 10 Automated Patch Clamping Using the QPatch / Kenneth A. Jones, Nicoletta Garbati, Hong Zhang, and Charles H. Large -- 11 High-Throughput Screening of the Cyclic AMP-Dependent Protein Kinase -- (PKA) Using the Caliper Microfluidic Platform / Leonard J. Blackwell, Steve Birkos, Rhonda Hallam, Gretchen Van De Carr, Jamie Arroway, Carla M. Suto, and William P. Janzen -- 12 Use of Primary Human Cells in High-Throughput Screens / Angela Dunne, Mike Jowett, and Stephen Rees
Beschreibung:XII, 268 S. Ill., graph. Darst. 26 cm

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