Genetics and randomness:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Boca Raton, Fla. [u.a.]
CRC Press
2010
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XIII, 169 S. Ill., graph. Darst. |
| ISBN: | 9781420078855 1420078852 |
Internformat
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| 245 | 1 | 0 | |a Genetics and randomness |c Anatoly Ruvinsky |
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| 650 | 4 | |a Stochastic processes | |
| 650 | 4 | |a Natural selection | |
| 650 | 4 | |a Variation (Biology) | |
| 650 | 4 | |a Genetic Variation | |
| 650 | 4 | |a Evolution, Molecular | |
| 650 | 4 | |a Genetic Drift | |
| 650 | 4 | |a Recombination, Genetic | |
| 650 | 4 | |a Uncertainty | |
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Datensatz im Suchindex
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|---|---|
| adam_text |
Titel: Genetics and randomness
Autor: Ruvinsky, Anatoly
Jahr: 2010
Contents
Preface xi
Chapter 1 Limits and uncertainty in nature and logic 1
Limits of nature 1
Quantum uncertainty principle 4
Statistical mechanics and Brownian motion 7
Randomness in mathematics 10
Limits of reasoning: randomness and complexity as the general
feature of nature and mind 14
Summary 16
Note 16
References 16
Chapter 2 Quantum fluctuations, mutations, and
"fixation" of uncertainty 19
Nature of genes and mutations: the early attempts 19
Mutations and repair 29
Types of mutations 29
Keto-enol transitions and quantum uncertainty 30
Induced mutations and DNA repair 34
How do random molecular events like mutations
become facts of life? 35
Somatic and germ cell mutations 36
Quantum uncertainty and unpredictability of life 37
Other quantum phenomena and life 38
Summary 38
References 39
Chapter 3 Recombination and randomness 41
What is recombination? 41
Crossing-over 44
vi Contents
Molecular nature of recombination 49
Distribution of cross-overs along chromosomes 50
Meiotic recombination generates randomness 51
Origin of meiosis and sex 52
Recombination and chromosome rearrangements 53
Genome transformations and speciation 54
Intron-exon structure of eukaryotic genes: randomness again 56
Arranged randomness and immune response 57
Summary 59
References 60
Chapter 4 Uncertainty of development 63
Phenotype and genotype 63
Stochasticity of development: clones and twins 65
Mosaics and chimeras 68
Alternative splicing and variety of proteins 69
Stochastic nature of gene activity 72
Epigenetic basis of developmental variability 73
Random gene inactivation events 77
Random X chromosome inactivation 79
Gene networks and canalization 81
Types of randomness 84
Summary 86
References 88
Chapter 5 Organized randomness 93
Gregor Mendel's vision 93
Random segregation, uncertainty, and
combinatorial variability 99
Genes and chromosomes that violate the law 101
Why is the first Mendelian law so common? 105
Randomness rules 106
Summary 108
References 109
Chapter 6 Random genetic drift and "deterministic"
selection Ill
The discovery of genetic drift Ill
Neutral mutations in evolution 122
Is natural selection deterministic? 126
Adaptations and stochastic processes in evolution 128
Summary 131
References 132
Contents vii
Chapter 7 Life: Making uncertainty certain 135
Order from chaos 136
What is life? 140
The old comparison: physics and biology 142
Natural selection: biology and beyond 145
Randomness: nuisance or essence? 148
The reason and the consequence 150
Summary 155
References 156
Index 159 |
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| illustrated | Illustrated |
| indexdate | 2024-12-06T17:00:42Z |
| institution | BVB |
| isbn | 9781420078855 1420078852 |
| language | English |
| lccn | 2009014187 |
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| physical | XIII, 169 S. Ill., graph. Darst. |
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| spelling | Ruvinsky, Anatoly Verfasser aut Genetics and randomness Anatoly Ruvinsky Boca Raton, Fla. [u.a.] CRC Press 2010 XIII, 169 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Genetics Stochastic processes Natural selection Variation (Biology) Genetic Variation Evolution, Molecular Genetic Drift Recombination, Genetic Uncertainty Genetische Variabilität (DE-588)4264352-1 gnd rswk-swf Natürliche Auslese (DE-588)4132359-2 gnd rswk-swf Genetik (DE-588)4071711-2 gnd rswk-swf Gendrift (DE-588)4357334-4 gnd rswk-swf Genetik (DE-588)4071711-2 s Natürliche Auslese (DE-588)4132359-2 s DE-604 Genetische Variabilität (DE-588)4264352-1 s Gendrift (DE-588)4357334-4 s b DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018631736&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ruvinsky, Anatoly Genetics and randomness Genetics Stochastic processes Natural selection Variation (Biology) Genetic Variation Evolution, Molecular Genetic Drift Recombination, Genetic Uncertainty Genetische Variabilität (DE-588)4264352-1 gnd Natürliche Auslese (DE-588)4132359-2 gnd Genetik (DE-588)4071711-2 gnd Gendrift (DE-588)4357334-4 gnd |
| subject_GND | (DE-588)4264352-1 (DE-588)4132359-2 (DE-588)4071711-2 (DE-588)4357334-4 |
| title | Genetics and randomness |
| title_auth | Genetics and randomness |
| title_exact_search | Genetics and randomness |
| title_full | Genetics and randomness Anatoly Ruvinsky |
| title_fullStr | Genetics and randomness Anatoly Ruvinsky |
| title_full_unstemmed | Genetics and randomness Anatoly Ruvinsky |
| title_short | Genetics and randomness |
| title_sort | genetics and randomness |
| topic | Genetics Stochastic processes Natural selection Variation (Biology) Genetic Variation Evolution, Molecular Genetic Drift Recombination, Genetic Uncertainty Genetische Variabilität (DE-588)4264352-1 gnd Natürliche Auslese (DE-588)4132359-2 gnd Genetik (DE-588)4071711-2 gnd Gendrift (DE-588)4357334-4 gnd |
| topic_facet | Genetics Stochastic processes Natural selection Variation (Biology) Genetic Variation Evolution, Molecular Genetic Drift Recombination, Genetic Uncertainty Genetische Variabilität Natürliche Auslese Genetik Gendrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018631736&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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