The neurobiology of aggression and rage:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Boca Raton [u.a.]
CRC Press
2005
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 293 S. Ill., graph. Darst. |
| ISBN: | 9780415308342 0415308348 |
Internformat
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| 100 | 1 | |a Siegel, Allan |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a The neurobiology of aggression and rage |c Allan Siegel |
| 264 | 1 | |a Boca Raton [u.a.] |b CRC Press |c 2005 | |
| 300 | |a 293 S. |b Ill., graph. Darst. | ||
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| 650 | 2 | |a Neurobiology | |
| 650 | 2 | |a Aggression |a physiology | |
| 650 | 2 | |a Rage |a physiology | |
| 650 | 7 | |a Agressie |2 gtt | |
| 650 | 7 | |a Agressief gedrag |2 gtt | |
| 650 | 4 | |a Agressivité - Aspect physiologique | |
| 650 | 4 | |a Colère - Aspect physiologique | |
| 650 | 7 | |a Neurobiologie |2 gtt | |
| 650 | 4 | |a Neuropsychologie | |
| 650 | 7 | |a Neuropsychologie |2 gtt | |
| 650 | 7 | |a Woede |2 gtt | |
| 650 | 4 | |a Aggressiveness |x Physiological aspects | |
| 650 | 4 | |a Anger |x Physiological aspects | |
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Datensatz im Suchindex
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|---|---|
| adam_text | Table of Contents
Chapter 1 What Is Aggression? 1
Animal Models of Aggression 2
Other Models of Aggression 5
Is Aggressive Behavior Bimodal? 5
Offensive and Defensive Behavior 5
Offense 6
Defense 7
Aggression Induced by Brain Stimulation in Rat: Limitations of
Offense-Defense Dichotomy 8
Defensive Rage (Affective Defense) versus Predatory Attack 9
Do Equivalents to Affective Defense and Predatory Attack
Exist in Humans? 10
Affective Defense 10
Predatory Attack 11
Hostile versus Instrumental Aggression 13
Summary 14
References 14
Chapter 2 History of the Neurology of Aggression and Rage 17
Effects of Ablations 17
Attempts to Identify Anatomical Locus of Rage Mechanism, and Notion of
Sham Rage 18
More Selective Forebrain and Brainstem Lesions 19
Hypothalamus 19
Midbrain Periaqueductal Gray 21
Limbic Structures 21
Stimulation of Regions Mediating Aggression and Rage 22
References 24
Chapter 3 The Neuroanatomy of Aggression and Rage 29
Neuroanatomical Methods 29
Pathways Mediating Defensive Rage in Cats 31
Hypothalamus 31
Midbrain Periaqueductal Gray 37
Pathways Mediating Predatory Attack in Cats 39
Relationship between Predatory Attack and Defensive Rage: Linkage
between Medial and Lateral Hypothalamus 41
Hypothalamic Aggression in Rats 44
Nature of Attack Response 45
Attack Sites in Rats 46
Efferent Pathways from Hypothalamus Mediating Attack in Rats 47
Summary 48
References 49
Chapter 4 Physiological Processes and Mechanisms 53
Diencephalon and Brainstem 53
Relative Roles of Hypothalamus, Brainstem, and Other Regions in
Expression of Aggression and Rage 53
Hypothalamus 54
Midbrain PAG and Related Structures 55
Evidence from Studies Conducted in Rats 58
Aggression in Other Species Induced by Brain Stimulation 59
Physiological Properties of Stimulation-Induced Aggression and Rage 60
Modulation from Hypothalamus and Periaqueductal Gray 60
Other Effects of Electrical Stimulation of Attack Sites in Cats 61
Neurophysiological Relationships 62
Other Regions Associated with Rage and Aggression 62
Role of Sensory Processes in Aggressive Behavior 63
Olfaction 63
Tactile Stimulation 64
Motor Aspects of Predatory Attack 67
Behavioral Properties of Attack Behavior 69
Discriminative Properties of Aggression 69
Reinforcing Properties of Rage and Aggression 69
Aggression or Feeding? 71
Avoidance, Play, and Predatory Attack 72
Summary 72
References 74
Chapter 5 Limbic System I: Behavioral, Anatomical, and Physiological
Considerations 81
Hippocampal Formation 82
Anatomical Considerations 82
Relationship to Aggression and Rage 83
Septal Area 88
Anatomical Considerations 88
Relationship to Aggression and Rage 88
Amygdala 94
Anatomical Considerations 94
Afferent Connections 95
Efferent Connections 96
Relationship to Aggression and Rage 96
Effects of Seizures 102
Seizures Induced by Electrical Stimulation of Amygdala 102
Effects of Amygdaloid Seizures on Spontaneously
Elicited Attack 104
Prefrontal Cortex and Cingulate Gyrus 107
Background 107
Anatomical Considerations 108
Relationship to Aggression and Rage 108
Related Structures of Limbic Forebrain: Substantia Innominata and Bed
Nucleus of Stria Terminalis 113
Bed Nucleus of Stria Terminalis 113
Anatomical Considerations 113
Relationship to Aggression and Rage 113
Substantia Innominata 114
Anatomical Considerations 114
Relationship to Aggression 115
Limbic System and Human Aggression 116
Summary 118
References 119
Chapter 6 Limbic System II: Functional Neuroanatomy 127
Methods Used 127
Study Results 128
Hippocampal Formation 128
Principal Findings 128
Conclusions 129
Septal Area 130
Principal Findings 130
Conclusions 131
Amygdala 132
Principal Findings 132
Basotnedial Nucleus 132
Cortical Nucleus 133
Medial Nucleus 133
Amygdalo-Hippocampal Area 134
Bed Nucleus of Stria Terminalis 134
Anterior Amygdaloid Area 135
Lateral Nucleus 136
Central Nucleus 136
Basolateral Nucleus 137
Prepyriform Cortex 137
Entorhinal Cortex 137
Substantia Innominata 138
Conclusions 138
Prefrontal Cortex and Associated Thalamus Nuclei 140
Principal Findings 140
Medial Prefrontal, Sulcal, and Infralimbic Cortices 142
Mediodorsal Thalamic Nucleus 144
Midline Thalamic Nuclei 144
Conclusions 147
Overall Conclusions 148
Abbreviations Used in Figures 157
References 158
Chapter 7 The Neurochemistry of Rage and Aggression 161
Acetylcholine 162
Synthesis and Removal 162
Distribution and Functions 163
Role of ACh in Aggression and Rage 163
Effects of Systemic Administration of Cholinergic Agents 163
Effects of Intracerebral Microinjections of
Cholinergic Agents 164
Genetic Approach 165
Summary 165
Norepinephrine 166
Synthesis and Removal 166
Distribution and Functions 166
Role of Norepinephrine in Aggression and Rage 166
Effects of Systemic and Intracerebroventricular
Administration of Noradrenergic Agents 166
Neurochemical Measurements 167
Summary 170
Dopamine 171
Synthesis and Removal 171
Distribution and Functions 171
Role of Dopamine in Aggression and Rage 172
Effects of Systemic and Intracerebroventricular
Administration of Dopaminergic Agents 172
Neurochemical Measurements 174
Genetic Approaches 174
Intracerebral Administration of Dopaminergic Compounds 174
Summary 175
Serotonin 175
Synthesis and Removal 175
Distribution and Functions 177
Role of Serotonin in Aggression and Rage 177
Lesions or Stimulation of Serotonergic Nuclei 177
Neurochemical Depletion of Serotonin 178
Depletion of Serotonin Levels by Diet 179
Genetic Manipulation of Brain Serotonin Levels 180
Peripheral Administration of Serotonergic Compounds 181
Central Administration of Serotonergic Compounds 182
Neurochemical Measurements and Approaches 183
Summary 184
Peptides 184
Opioid Peptides 184
Characterization 184
Distribution and Functions 185
Role of Enkephalins in Aggression and Rage 185
Studies Conducted in Rodents 185
Studies Conducted in Cats 186
Systemic Administration of Opioid Compounds 186
Intracerebral Administration of Opioid Compounds 186
Summary 191
Substance P 191
Characterization, Distribution, and Functions 191
Role of SP in Rage and Aggression 191
Cholecystokinin (CCK) 194
Characterization, Distribution, and Functions 194
Role of CCK in Defensive Rage Behavior 195
Summary 196
Amino Acids 197
Excitatory Amino Acids (Glutamate) 197
Synthesis and Removal 197
Distribution and Functions 198
Role of Excitatory Amino Acids in Defensive
Rage Behavior 198
Summary 200
Inhibitory Amino Acids (GABA) 200
Synthesis and Removal 200
Distribution and Functions 200
Role of Inhibitory Amino Acids in Defensive Rage and
Predatory Attack Behavior 201
Summary 204
Can Substances of Abuse, Psychotropic Drugs, and Antidepressant
Drugs Influence Aggression? 204
Substances of Abuse 204
Opioid Peptides 204
Alcohol: Linkage between Alcohol Consumption and
Violent Behavior 205
i
Psychotropic and Antidepressant Drugs 208
Summary 209
References 210
Chapter 8 Aggression and Hormonal Status 223
M. Demetrikopoulos and A. Siegel
Testosterone and Aggressive Behavior 223
Experimental Manipulation of Testosterone Levels 223
Seasonal Variations in Testosterone Levels 226
Testosterone Levels during Development 228
Testosterone s Role in Human Aggression 230
Estrogen and Aggressive Behavior 234
Experimental Manipulation of Estrogen Levels 234
Naturally Occurring Variations in Estrogen Levels 235
Estrogen Levels during Development 236
Progesterone and Aggressive Behavior 234
Experimental Manipulation of Progesterone Levels 237
Progesterone Levels during Development 238
Adrenal Steroids and Aggressive Behavior 238
Modulation of Hormonal-Aggression Interactions by Ethanol and
Illicit Drugs 239
Comments and Conclusions 239
References 241
Chapter 9 Aggression and Immune Function 251
M. Demetrikopoulos and A. Siegel
Social Status Effects on Immunity 251
Stable Hierarchical Groups 251
Hierarchy Formation 253
Summary 254
Effects of Aggression on Recipient s Immune Function 254
Social Disruption 255
Social Confrontation 256
Summary 257
Effects of Aggression on Perpetrator s Immune Function 258
Social Isolation-Induced Fighting 258
Resident-Intruder Interaction 258
Strain Differences in Behavior and Immune Function 257
Aggression, Hostility, and Marital Conflict: Effects on
Immunity in Humans 260
Summary 260
Can Immune Events Affect Aggression? 261
Immune Challenge Effects 261
i
Autoimmune Disorder Effects 262
Potential Mediators 262
Summary 262
Converging Neuronal Circuitry 263
Role of Cytokines 263
Role of Periaqueductal Gray 264
Secondary Stress Effects 264
Summary 264
Overall Summary 266
References 265
Chapter 10 Genetics and Aggression 269
Studies Conducted in Animals 269
Early Behavioral Studies 269
Recent Studies 270
Genetic Effects on Neuroanatomic Circuitry and Neurotransmitter-
Receptor Systems 271
Studies Conducted in Humans 272
Summary 273
References 273
Chapter 11 Future Directions and Perspectives 277
References 283
Index 285
I
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| spelling | Siegel, Allan Verfasser aut The neurobiology of aggression and rage Allan Siegel Boca Raton [u.a.] CRC Press 2005 293 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neurobiology Aggression physiology Rage physiology Agressie gtt Agressief gedrag gtt Agressivité - Aspect physiologique Colère - Aspect physiologique Neurobiologie gtt Neuropsychologie Neuropsychologie gtt Woede gtt Aggressiveness Physiological aspects Anger Physiological aspects Neurobiologie (DE-588)4041871-6 gnd rswk-swf Aggression (DE-588)4000732-7 gnd rswk-swf Wut (DE-588)4133872-8 gnd rswk-swf Aggression (DE-588)4000732-7 s Neurobiologie (DE-588)4041871-6 s DE-604 Wut (DE-588)4133872-8 s HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017746253&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Siegel, Allan The neurobiology of aggression and rage Neurobiology Aggression physiology Rage physiology Agressie gtt Agressief gedrag gtt Agressivité - Aspect physiologique Colère - Aspect physiologique Neurobiologie gtt Neuropsychologie Neuropsychologie gtt Woede gtt Aggressiveness Physiological aspects Anger Physiological aspects Neurobiologie (DE-588)4041871-6 gnd Aggression (DE-588)4000732-7 gnd Wut (DE-588)4133872-8 gnd |
| subject_GND | (DE-588)4041871-6 (DE-588)4000732-7 (DE-588)4133872-8 |
| title | The neurobiology of aggression and rage |
| title_auth | The neurobiology of aggression and rage |
| title_exact_search | The neurobiology of aggression and rage |
| title_full | The neurobiology of aggression and rage Allan Siegel |
| title_fullStr | The neurobiology of aggression and rage Allan Siegel |
| title_full_unstemmed | The neurobiology of aggression and rage Allan Siegel |
| title_short | The neurobiology of aggression and rage |
| title_sort | the neurobiology of aggression and rage |
| topic | Neurobiology Aggression physiology Rage physiology Agressie gtt Agressief gedrag gtt Agressivité - Aspect physiologique Colère - Aspect physiologique Neurobiologie gtt Neuropsychologie Neuropsychologie gtt Woede gtt Aggressiveness Physiological aspects Anger Physiological aspects Neurobiologie (DE-588)4041871-6 gnd Aggression (DE-588)4000732-7 gnd Wut (DE-588)4133872-8 gnd |
| topic_facet | Neurobiology Aggression physiology Rage physiology Agressie Agressief gedrag Agressivité - Aspect physiologique Colère - Aspect physiologique Neurobiologie Neuropsychologie Woede Aggressiveness Physiological aspects Anger Physiological aspects Aggression Wut |
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