Intracellular niches of microbes: a pathogens guide through the host cell
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| Format: | Buch |
| Sprache: | English |
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Weinheim
WILEY-VCH
2009
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| Beschreibung: | XXIII, 712 S. Ill. |
| ISBN: | 9783527322077 |
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| 245 | 1 | 0 | |a Intracellular niches of microbes |b a pathogens guide through the host cell |c ed. by Ulrich E. Schaible ... |
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| 650 | 4 | |a Bacterial Physiological Phenomena | |
| 650 | 4 | |a Host-Pathogen Interactions | |
| 650 | 4 | |a Host-parasite relationships | |
| 650 | 4 | |a Intracellular pathogens | |
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Datensatz im Suchindex
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| adam_text |
Titel: Intracellular niches of microbes
Autor: Schaible, Ulrich E.
Jahr: 2009
VII
Contents
Foreword V
List of Contributors XVII
Part I General Aspects 1
1 Introduction: The Evolution of Intracellular Life Forms
and their Niches 3
Ulrich E. Schaible and Albert Haas
1.1 A Short History of Theories and Discoveries 3
1.2 A Look Through the Microscope of Evolution 5
1.3 Continuous Exchange of Information 9
1.4 Evolution of Intracellular Parasitism 10
1.5 Intracellular Symbionts: Tamed or Acclimatized Parasites? 13
1.6 An Ecological View of Intracellular life 14
1.7 The Immunologist's View 16
1.8 The Public Health View 17
1.9 The Book 18
References 18
2 Limited Genomes and Gene Transfer in the Evolution
of Intracellular Parasitism and Symbiosis 21
Narapom Somboonna and Deborah Dean
2.1 Introduction to Gene Transfer and Evolution 21
2.2 Gene Transfer in Intracellular Bacterial Parasites 23
2.3 Gene Transfer in Intracellular Symbionts 27
2.4 Gene Transfer in Intracellular Parasites and Fungi 29
2.5 Summary and Outlook 30
References 32
3 Phagocytosis: Early Events in Particle Recognition and Uptake 37
Cabriela Cosio and Sergio Crinstein
3.1 Phagocytosis: An Overview 37
Intracdlular Niches of Microbes. Edited by Ulrich E. Schaible and Albert Haas
Copyright © 2009 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim
ISBN: 978-3-527-32207-7
VIII Contents
3.2 Recognition of Target Particles 38
3.3 Signaling Events Upon Ligand Recognition 42
3.4 Membrane Dynamics During Phagocytosis 46
3.5 Phagosome Maturation 48
3.6 Inflammatory Signals Linked to Phagocytosis 50
3.7 Concluding Remarks 52
References 52
4 Cellular Model Systems Used to Study Phagosome Biogenesis 65
Michael Steinert
4.1 From Grazing to Host Defense 65
4.2 Dictyostelium, a Professional Phagocyte at the Border
of Multicellularity 66
4.3 Dictyostelium, a Surrogate Host for Legionella, Mycobacterium
and Other Pathogens 67
4.4 legiowe/Ja-directed Phagosome Biogenesis 70
4.5 The Whole Animal Model Drosophila melanogaster 72
4.6 Infection of Drosophila Phagocytes 73
4.7 Conclusions 74
References 75
5 Methods Used to Study Phagosome Biogenesis 77
Albert Haas
5.1 Describing the World Within - Whole-Cell Assays
for Phagosome Contents 77
5.2 Biochemical Analysis and Assays with Purified Phagosomes 87
5.3 Use of Fluorescence-Activated Cell Sorting (FACS)
in Phagosome Research 88
5.4 Knockdown, Knockout and Phagosome Research 89
5.5 Transcriptomics as a Phagosome Environmental Sensor 90
References 91
6 In Vitro Fusion Assays with Phagosomes 95
Ulrike Becken and Albert Haas
6.1 Introduction 95
6.2 A Variety of Assays 96
6.3 Studying Normal Maturation . 101
6.4 . and the Pathogenic Case 103
References 105
7 Phagosome Proteomes Unite! A Virtual Model of Maturation
as a Tool to Study Pathogen-Induced Changes 107
Rigis Dieckmann and Thierry Soldati
7.1 Background 107
7.2 A Methods Guide to Phagosome Proteomics 108
Contents IX
7.3 Particle-Induced Impact on Phagosome Isolation 112
7 A Comparative Proteomics of Microbe-Containing Vacuoles 113
7.5 Conclusions 121
References 122
8 Phagosome-Cytoskeleton Interactions 125
Maximiliano G. Gutierrez and Careth Griffiths
8.1 Introduction 125
8.2 The Actin Cytoskeleton. General Background 126
8.3 The Microtubule Cytoskeleton - General Background 136
8.4 Concluding Remarks 140
References 140
9 Intracellular Microbe Whole-Genome Expression Profiling:
Methodological Considerations and Biological Inferences 145
Simon J. Waddell and Philip D. Butcher
9.1 Introduction 145
9.2 Methodological Considerations 146
9.3 Biological Inferences from Expression Profiling 149
9.4 Concluding Remarks 155
References 156
10 Everybody Has A Home of Their Own - "The Phagosome Zoo" 159
Albert Haas
10.1 Come On In, Get Killed! Death in the Shredder 159
10.2 Professionals and Laypersons 163
10.3 Come On In, Have Fun! Life in a Golden Cage 165
10.4 Immune Activation and the Loss of Home 184
10.5 Why Not Pathogens in Peroxisomal Vacuoles? 185
10.6 Looking for a New Home 186
10.7 Summary 186
References 187
11 Consequences of Pathogen Compartmentation
for Therapeutic Intervention 191
Albert Haas and Ulrich Schaible
11.1 The Problem 191
11.2 Consequences of Intracellular Localization for Treatment
with Antibiotics 191
11.3 Many Roads Lead Into the Host Cell 195
11.4 And Off You Go. 197
11.5 "Small Molecules" Pave the Road to the Future 197
11.6 How Do You Come Up With A Successful "Small Molecule?" 198
11.7 A Few More, Maybe Even Practicable, Ideas For the Future . 199
References 200
X Contents
12 The Immune Response to Intracellular Pathogens 203
Daniel S. Korbel and Ulrich E. Schaible
12.1 General Introduction 203
12.2 Innate Immunity 206
12.3 Adaptive Immunity 217
12.4 Conclusion 230
12.5 Excursus - Immunity in Plants 230
References 232
Part II Selected Pathogens 235
IIA Vacuolar Bacteria 235
13 Afipiafelis 237
Bianca E. Schneider and Albert Haas
13.1 Introduction of Afipia felis and its Role in Cat Scratch Disease 237
13.2 Uptake and Intracellular Compartmentation of Afipia felis
in Murine Macrophages 240
13.3 The Port of Entry Paves the Way for Non-Endocytic
Compartmentation 242
13.4 Host and Pathogen Determinants Involved in Diverted
Phagosome Biogenesis 250
13.5 Immunology of the A^pia-Containing Phagosome 251
13.6 Summary and Outlook 252
References 253
14 Brucella 255
Monika Kalde, Edgardo Moreno, and Jean-Pierre Corvel
14.1 Introduction 255
14.2 Characterization of Intra-Host Cell Compartmentation of Brucella
and its Relationship to Virulence 258
14.3 Factors Involved in Diverted Phagosome Maturation and
Compartment Maintenance 262
14.4 Immunology of Phagosomes Containing Brucella 266
14.5 Conclusions 269
References 270
15 Chlamydiae 273
Ted Hackstadt
15.1 Diseases 273
15.2 Characterization of the Chlamydial Inclusion and its Relationship
to Virulence 273
15.3 Genes Involved in Chlamydial Inclusion Maturation 275
15.4 Immunology of the Chlamydial Inclusion 281
15.5 Summary and Outlook 283
References 283
Contents XI
16 Coxiella burnetii 287
Stacey D. Cilk, Daniel E. Voth, and Robert A. Heinzen
16.1 Coxiella burnetii and Q Fever 287
16.2 Characterization of the Intrahost Compartment of Coxiella
and its Relationship to Virulence 288
16.3 Genes Involved in Diverted Phagosome Maturation/
Compartment Maintenance 295
16.4 Immunology of the Coxiella Parasitophorous Vacuole 297
16.5 Summary and Outlook 297
References 298
17 Ehrlichia and Anaplasma 301
Yasuko Rikihisa
17.1 Ehrlichia and Anaplasma and the Illnesses They Cause in Humans 301
17.2 Characterization of Host Cell Compartmentalization
of E. chaffeensis and A. phagocytophilum 302
17.3 Microbe Genes Involved in Subverting Phagosome
Maturation/Compartment Maintenance 310
17.4 Immunology of Phagosomes Containing E. chaffeensis
and A. phagocytophilum 311
17.5 Summary and Outlook 312
References 312
18 Legionella pneumophila 315
Alyssa Ingmundson and Craig R. Roy
18.1 Legionella pneumophila Biology 315
18.2 The Intracellular Compartment of I. pneumophila 315
18.3 Requirements for Intracellular Replication 316
18.4 The Immune Response to L. pneumophila Infection 320
18.5 Summary and Outlook 322
References 323
19 Mycobacterium tuberculosis and His Comrades 327
Ulrich E. Schaible
19.1 Pathogenic Mycobacteria 327
19.2 Intracellular Compartment and Virulence Properties
of Mycobacteria 332
19.3 Host Response and Transmission 346
19.4 Outlook 348
References 349
20 Rhodococcus equi and Nocardia asteroides 355
Kristine von Bargen and Albert Haas
20.1 Rhodococcus and Nocardia and Illnesses Caused by them 355
20.2 Characterization of Intra-Host Cell Compartmentation and
its Relationship to Virulence 357
XII Contents
20.3 Genes Involved in Diverted Phagosome Maturation or
Compartmentation and its Maintenance 361
20.4 Immunology of Phagosomes Containing R. equi or
N. asteroides 364
20.5 Summary and Outlook 367
References 368
21 Salmonella 373
Olivia Steele-Mortimer
21.1 Introduction 373
21.2 Characterization of the SCV and its Role in
Virulence 376
21.3 Factors Affecting SCV Biogenesis 378
21.4 Immunology of the SCV 383
21.5 Summary 384
References 384
IIB Intracytosolic Bacteria 391
22 Burkholderia pseudomallei 393
Joanne M. Stevens and Mark P. Stevens
22.1 Burkholderia pseudomallei and Melioidosis 393
22.2 An Overview of the Intracellular Life of B. pseudomallei 394
22.3 Genome Structure and Diversity of B. pseudomallei 395
22.4 Cell Contact and Adherence 396
22.5 Invasion 398
22.6 Endosome Escape 400
22.7 Actin-Based Motility 401
22.8 Cell Fusion 404
22.9 Intracellular Replication 405
22.10 Immunology of B. pseudomallei-Host Cell Interactions 406
22.11 Concluding Remarks 407
References 408
23 Francisella tularensis 415
Lee-Ann H. Allen and Grant S. Schulert
23.1 Francisella tularensis and Tularemia 415
23.2 F. tularensis Inhibits Phagosome Maturation Prior to Egress
and Replication in the Cytosol 416
23.3 F. tularensis Virulence Factors that Disrupt Phagocyte
Function 422
23 A Immunology of Phagosome and Host Defense 424
23.5 Summary and Outlook 424
References 425
Contents XIII
24 Listeria monocytogenes 431
Damien Balestrino and Pascale Cossart
24.1 Listeria and listeriosis 431
24.2 The Intracellular Lifestyle of Listeria and its Relationship
to Virulence 435
24.3 Bacterial Factors Involved in Escape From the
Vacuole 441
24.4 Survey Inside the Phagosome and Phagosome
Maturation 446
24.5 Summary and Outlook 451
References 452
25 Mycobacterium marinum 455
Monica Hagedom and Thierry Soldati
25.1 An Introduction to Mycobacterium marinum and the
Illness Caused by it 455
25.2 Characterization of Intra-Host Cell Compartmentation
of M. marinum and its Relationship to Virulence 458
25.3 Genes Involved in Diverting Phagosome Maturation
and in Compartment Maintenance 461
25.4 Immunological Aspects of M. marinum Infection 463
25.5 What's Next? (Outlook and Summary) 464
References 465
26 Rickettsia 469
Sanjeev K. Sahni, Elena Rydkina, and DavidJ. Silverman
26.1 Introduction to Rickettsiae and Rickertsial Diseases 469
26.2 Intracytoplasmic Behavior of Rickettsiae 472
26.3 Host Cell Interactions with Pathogenic Rickettsia
Species 477
26.4 Animal Models and Immunology of Rickettsioses 479
26.5 Genomics and Proteomics of Rickettsia Species 480
26.6 Summary and Outlook 482
References 483
27 Shigella 485
Guy Iran Van Nhieu and Philippe Sansonetti
27.1 Introduction 485
27.2 Escape into the Cytoplasm and Intracytoplasmic
Replication 488
27.3 Genes Involved in Phagosome Escape and Intracytoplasmic
life 493
27A Host Defense Against Cytoplasmic Shigella 496
27.5 Summary and Outlook 499
References 499
XIV Contents
DC Intracellular Symbionts 505
28 Bacterial Symbionts of Plants 507
Kumiko Kambara, William J. Broughton, and William J. Deakin
28.1 Introduction to Rhizobia and Symbioses 507
28.2 Invasion of Plant Cells by Rhizobia and Arbuscular Mycorrhizae 508
28.3 Plant Genes Involved in Symbiosis Initiation 520
28.4 Symbiotic Signals Produced by Rhizobia 514
28.5 Summary and Outlook 521
References 521
29 Cyanobacterial and Algal Symbioses 527
Goran Kovacevic, Jurgen M. Steiner, and Wolfgang Lqffelhardt
29.1 Introduction 527
29.2 Intracellular Cyanobacteria 527
29.3 Intracellular Algae 536
References 543
30 Insect Symbionts 547
Heike Feldhaar and Roy Cross
30.1 Introduction 547
30.2 Mutualistic Primary Endosymbionts with a Function in
Nutritional Upgrading 550
30.3 Endosymbionts that Interfere with Reproduction 554
30.4 Endosymbiont Communities 558
30.5 Conclusion and Future Directions 559
References 560
IID Parasites and Fungi 565
31 Histoplasma capsulatum 567
S. L Newman
31.1 Histoplasma capsulatum and Histoplasmosis 567
31.2 Characterization of the Macrophage Phagosomes Containing
H. capsulatum Yeasts 569
31.3 Genes Involved in the Intracellular Survival of H. capsulatum Yeasts 5 73
31.4 Immunology of Phagosomes Containing H. capsulatum Yeasts 579
31.5 Summary and Outlook 579
References 580
32 Leishmania: L. mexicana vs. donovani vs. major,
Amastigotes vs. Promastigotes 583
Christine Matte, Julia MalUgol, and Albert Descoteaux
32.1 Leishmania and Leishmaniases 583
Contents XV
32.2 Characterization of Intra-Host Cell Compartmentation of
Leishmania and its Relationships to Virulence 584
32.3 Leishmania Molecules Involved in Diverted Phagosome
Maturation/Compartment Maintenance 586
32.4 Immunology of Phagosomes Containing
Leishmania 592
32.5 Summary and Outlook 593
References 593
33 Plasmodium and Babesia 597
Markus Winterberg, Jude M. Przyborski, and Klaus Lingelbach
33.1 Introduction 597
33.2 Illness 599
33.3 Characterization of Intra-Host Compartmentation and its
Relationship to Virulence 600
33.4 From Parasite Cell Biology and Genomics to Drug Targets 607
33.5 Summary and Outlook 609
References 609
34 Theileria 613
Dirk Dobbelaere and Martin Baumgartner
34.1 Introduction to Theileria and the Disease 613
34.2 Characterization of the Intra-Host Cell Compartment .
Which Compartment? 615
34.3 Genes Involved in Host-Parasite Interaction 623
34.4 Immune Responses Directed Against the Schizont 625
34.5 Summary and Outlook 626
References 628
35 Toxoplasma gondii 633
L David Sibley
35.1 Introduction of Toxoplasma gondii and Toxoplasmosis 633
35.2 Characterization of the Intracellular Compartment Occupied
by T. gondii 635
35.3 Parasite Factors Involved in Maturation and Maintenance
of the Parasite-Containing Vacuole 638
35.4 Immunology of the Intracellular Compartment Occupied
by T. gondii 641
35.5 Summary and Outlook 646
References 647
36 Trypanosoma cruzi 655
Martin C. Taylor
36.1 Introduction: The Parasite and its Disease 655
36.2 Intracellular Compartmentation of T. cruzi 657
XVI Contents
36.3 Maintenance of the Infected Cell 663
36.4 Immunology of T. cruzi Infection 664
36.5 Summary and Outlook 666
References 667
37 Trichinella and the Nurse Cell 669
David 8. Cuiliano and Yelena Oksov
37.1 Introduction to Trichinella and Trichinellosis 669
37.2 Remodeling of the Host Cell Compartment by Trichinella 671
37.3 Parasite Molecules Involved in the Remodeling and Maintenance
of the Nurse Cell Complex 679
37.4 The Immunology of the Nurse Cell 684
37.5 Future Work and Outlook 686
References 686
Index 689 |
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| id | DE-604.BV035667868 |
| illustrated | Illustrated |
| indexdate | 2024-07-20T10:16:29Z |
| institution | BVB |
| isbn | 9783527322077 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-017722176 |
| oclc_num | 280446928 |
| open_access_boolean | |
| owner | DE-20 DE-11 |
| owner_facet | DE-20 DE-11 |
| physical | XXIII, 712 S. Ill. |
| publishDate | 2009 |
| publishDateSearch | 2009 |
| publishDateSort | 2009 |
| publisher | WILEY-VCH |
| record_format | marc |
| spelling | Intracellular niches of microbes a pathogens guide through the host cell ed. by Ulrich E. Schaible ... Weinheim WILEY-VCH 2009 XXIII, 712 S. Ill. txt rdacontent n rdamedia nc rdacarrier Bacterial Physiological Phenomena Host-Pathogen Interactions Host-parasite relationships Intracellular pathogens Microbiological Processes Models, Biological Wirtszelle (DE-588)4232591-2 gnd rswk-swf Pathogener Mikroorganismus (DE-588)4044890-3 gnd rswk-swf Pathogener Mikroorganismus (DE-588)4044890-3 s Wirtszelle (DE-588)4232591-2 s DE-604 Schaible, Ulrich E. (DE-588)112892930 edt text/html http://deposit.dnb.de/cgi-bin/dokserv?id=3192135&prov=M&dok_var=1&dok_ext=htm Inhaltstext HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017722176&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Intracellular niches of microbes a pathogens guide through the host cell Bacterial Physiological Phenomena Host-Pathogen Interactions Host-parasite relationships Intracellular pathogens Microbiological Processes Models, Biological Wirtszelle (DE-588)4232591-2 gnd Pathogener Mikroorganismus (DE-588)4044890-3 gnd |
| subject_GND | (DE-588)4232591-2 (DE-588)4044890-3 |
| title | Intracellular niches of microbes a pathogens guide through the host cell |
| title_auth | Intracellular niches of microbes a pathogens guide through the host cell |
| title_exact_search | Intracellular niches of microbes a pathogens guide through the host cell |
| title_full | Intracellular niches of microbes a pathogens guide through the host cell ed. by Ulrich E. Schaible ... |
| title_fullStr | Intracellular niches of microbes a pathogens guide through the host cell ed. by Ulrich E. Schaible ... |
| title_full_unstemmed | Intracellular niches of microbes a pathogens guide through the host cell ed. by Ulrich E. Schaible ... |
| title_short | Intracellular niches of microbes |
| title_sort | intracellular niches of microbes a pathogens guide through the host cell |
| title_sub | a pathogens guide through the host cell |
| topic | Bacterial Physiological Phenomena Host-Pathogen Interactions Host-parasite relationships Intracellular pathogens Microbiological Processes Models, Biological Wirtszelle (DE-588)4232591-2 gnd Pathogener Mikroorganismus (DE-588)4044890-3 gnd |
| topic_facet | Bacterial Physiological Phenomena Host-Pathogen Interactions Host-parasite relationships Intracellular pathogens Microbiological Processes Models, Biological Wirtszelle Pathogener Mikroorganismus |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=3192135&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017722176&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT schaibleulriche intracellularnichesofmicrobesapathogensguidethroughthehostcell |