Advances in neuropharmacology:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2009
|
| Schriftenreihe: | International review of neurobiology
85 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Einzelaufnahme eines Zeitschr.-Bd. |
| Beschreibung: | XXVI, 464 S. Ill., graph. Darst. |
| ISBN: | 9780123748935 |
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Datensatz im Suchindex
| _version_ | 1804139357178691584 |
|---|---|
| adam_text | Titel: Advances in neuropharmacology
Autor: Bagetta, Giacinto
Jahr: 2009
CONTENTS
Contributors xv
Preface xxv
Involvement of the Prefrontal Cortex in Problem Solving
Hajime Mushiake, Kazuhiro Sakamoto, Naohiro Saito, Toshiro Inui,
Kazuyuki Aihara, and Jun Tanji
I. Introduction 2
II. Problem^Solving Behavior, Using a Path-Planning Task 4
III. Goal Representation and Planning in the Prefrontal Cortex 5
IV. Synchrony as a State Transition and Goal Transformation 6
V. Involvement of the Prefrontal Cortex in Planning and Execution 7
VI. Monitoring Action 8
VII. Summary and Conclusions 10
References 10
GluKl Receptor Antagonists and Hippocampal Mossy Fiber Function
Robert Nistico, Sheila Dargan, Stephen M. Fitzjohn,
David Lodge, David E. Jane, Graham L. Collingridge,
AND ZUNER A. BORTOLOTTO
I. Introduction 14
II. Pharmacological Tools to Investigate the Roles of KARs 15
III. Conclusions 24
References 24
Monoamine Transporter as a Target Molecule for Psychostimulants
Ichiro Sora, BingJin Li, Setsu Fumushima, Asami Fukui, Yosefu Arime,
Yoshiyuki Kasahara, Hiroaki Tomita, and Kazutaka Ikeda
I. Introduction 29
II. MAP-Induced Behavioral Sensitization 30
v
vi CONTENTS
III. MAP-Induced Hyperthermia and Neuronal Toxicity 31
References 32
Targeted Lipidomics as a Tool to Investigate Endocannabinoid Function
Giuseppe Astarita, Jennifer Geaga,
Faizy Ahmed, and Daniele Piomelli
I. Introduction 36
II. Endocannabinoids 36
III. Targeted Lipidomics of the Anandamide Pathway 40
IV. Targeted Lipidomics of the 2-AG Pathway 45
V. Conclusions 50
References 50
The Endocannabinoid System as a Target for Novel Anxiolytic and
Antidepressant Drugs
Silvana Gaetani, Pasqua Dipasquale,
Adele Romano, Laura Righetti, Tommaso Cassano,
Daniele Piomelli, and Vincenzo Cuomo
I. The Endogenous Cannabinoid System 58
II. Endocannabinoid Role in Emotional Reactivity and Mood Tone 60
III. Effects of Exogenously Administered Cannabinoid Agonists
and Antagonists 61
IV. Enhancement of the Endogenous Cannabinoid Tone 62
V. Faah-Knockout Phenotype 65
VI. Conclusions 65
References 66
GABAa Receptor Function and Gene Expression During
Pregnancy and Posfpartum
Giovanni Biggio, Maria Cristina Mostallino, Paolo Follesa,
Alessandra Concas, and Enrico Sanna
I. Introduction 74
II. Concentrations of 3ct,5a-THP in Rat Brain and Plasma During
Pregnancy and after Delivery 75
III. Changes in Synaptic GABAA-R Gene Expression During
Pregnancy and after Delivery 76
IV. Changes in Extrasynaptic ^Containing GABAA-R Gene Expression
During Pregnancy and after Delivery 80
CONTENTS vii
V. Changes in GABAA-R Function in the Rat Hippocampus During
Pregnancy and after Delivery 82
VI. Role of Neuroactive Steroids in GABAa-R Plasticity During Pregnancy:
Effects of Chronic Blockade of 5a^Reductase by Finasteride 85
VII. Conclusions 88
References 91
Early Postnatal Stress and Neural Circuit Underlying
Emotional Regulation
Machiko Matsumoto, Mitsuhiro Yoshioka, and Hiroko Togashi
I. Introduction 96
II. Behavioral Response and Neural Circuits in Early
Postnatal Stressed Rats 97
III. Conclusions 104
References 105
Roles of the Histaminergic Neurotransmission on
Methamphetamine-lnduced Locomotor Sensitization and Reward:
A Study of Receptors Gene Knockout Mice
Naoko Takino, Eiko Sakurai, Atsuo Kuramasu,
NOBUYUKI OkAMUKA, AND KAZUHIKO YANAI
I. Introduction 110
II. Methods and Materials Ill
III. Results and Discussion 112
IV. Conclusion 115
References 116
Developmental Exposure to Cannabinoids Causes Subtle and
Enduring Neurofunctional Alterations
Patrizia Campolongo, Viviana Trezza, Maura Palmery,
Luigia Trabace, and Vincenzo Cuomo
I. Introduction 118
II. Ontogeny of the Endocannabinoid System 119
III. Morphological and Neurofunctional Outcomes Induced
by Developmental Exposure to Cannabinoids 121
IV. Conclusions 127
References 128
viii CONTENTS
Neuronal Mechanisms for Pain-Induced Aversion: Behavioral Studies
Using a Conditioned Place Aversion Test
Masabumi Minami
I. Introduction 136
II. Anterior Cingulate Cortex 136
III. Amygdala 137
TV. Bed Nucleus of the Stria Terminalis 138
V. Other Brain Regions 140
VI. Conclusion 141
References 141
Bv8/Prokineticins and their Receptors: A New Pronociceptive System
Lucia Negri, Roberta Lattanzi, Elisa Giannini,
Michela Canestrelli, Annalisa Nicotra, and Pietro Melchiorri
I. Introduction 146
II. Bv8-Related Mammalian Peptides 146
III. Bv8-Prokineticin Receptors 150
IV. Role of the Bv8-PK2/PKR System in the Neurobiology of Pain 151
V. Conclusion 154
References 155
P2Y6-Evoked Microglial Phagocytosis
Kazuhide Inoue, Schuichi Koizumi, Ayako Kataoka,
hldetoshi tozaki-saitoh, and makoto tsuda
I. Introduction 159
II. Chemotaxis 160
III. Phagocytosis 161
IV. Conclusion 161
References 162
PPAR and Pain
Takehiko Maeda and Shiroh Kishioka
I. Introduction 166
II. Structure and Function of PPAR 167
III. PPARand Inflammation 168
rV. Neuroinflammation and Pain 169
V. Role of PPARin Pain 170
VI. Conclusion 173
References 174
CONTENTS IX
Involvement of Inflammatory Mediators in Neuropathic Pain
Caused by Vincristine
Norikazu Kiguchi, Takehiko Maeda, Yuka Kobayashi,
Fumihiro Saika, and Shiroh Kishioka
I. Introduction 180
II. Characterization of Neuropathic Pain Caused by Vincristine 181
III. Effects ofVincristine on the PNS 181
IV. Effects of Vincristine on the CNS 183
V. Other Anticancer Agents that Elicit Neuropathic Pain 185
VI. Conclusion 185
References 187
Nociceptive Behavior Induced by the Endogenous Opioid Peptides
Dynorphins in Uninjured Mice: Evidence with Intrathecal N-Ethylmaleimide
Inhibiting Dynorphin Degradation
Koichi Tan-No, Hiroaki Takahashi, Osamu Nakagawasai,
Fukie Niijima, Shinobu Sakurada, Georgy Bakalkin,
Lars Terenius, and Takeshi Tadano
I. Introduction 192
II. Interaction Between Dynorphins and the NMDA Receptor
Ion-Channel Complex 193
III. Nociceptive Behavior Induced by i.t.-Administered
Prodynorphin-Derived Peptides and Polycationic Compounds 194
IV- Degradation of Dynorphins by Cysteine Proteases 196
V. jV-Ethylmaleimide-Induced Nociceptive Behavior Mediated
Through Inhibition of Dynorphin Degradation 197
VI. Conclusion 200
References 201
Mechanism of Allodynia Evoked by Intrathecal
Morphine-3-Glucuronide in Mice
Takaaki Komatsu, Shinobu Sakurada, Sou Katsuyama,
Kengo Sanai, and Tsukasa Sakurada
I. Introduction 208
II. Mechanism of M3G-Induced Allodynia: Spinal Release of
Substance P and Glutamate 209
III. Mechanism of M3G-Induced Allodynia: Spinal Activation of
NO/cGMP/PKG Pathway 210
X CONTENTS
IV. Mechanism of M3G-Induced Allodynia: Spinal ERK Activation 211
V. Mechanism of M3G-Induced Allodynia; Spinal Astrocyte Activation 212
References 214
(-)-Linalool Attenuates Allodynia in Neuropathic Pain Induced
by Spinal Nerve Ligation in C57/BI6 Mice
Laura Berliocchi, Rosseixa Russo, Alessandra Levato, Vincenza
Fratto, Giacinto Bagetta, Shinobu Sakurada, Tsukasa Sakurada,
Nicola Biagio Mercuri, and Maria Tiziana Corasaniti
I. Introduction 222
II. Materials and Methods 223
III. Results 226
TV. Discussion 231
References 233
Intraplantar Injection of Bergamot Essential Oil into the Mouse Hindpaw:
Effects on Capsaicin-lnduced Nociceptive Behaviors
Tsukasa Sakurada, Hikari Kuwahata, Soh Katsuyama,
Takaaki Komatsu, Luigi Antonio Morrone, Maria Tiziana Corasaniti,
Giacinto Bagetta, and Shinobu Sakurada
I. Introduction 238
II. General Characteristics of Bergamot Essential Oil 239
III. Antinociception Induced by the Essential Oil of Bergamot 240
IV. Linalool-Induced Antinociceptive Activity 243
References 245
New Therapy for Neuropathic Pain
Hirokazu Mizoguchi, Chizuko Watanabe,
Akihiko Yonezawa, and Shinobu Sakurada
I. Neuropathic Pain 250
II. Drug Therapy of Neuropathic Pain—Effectiveness of
Narcotic Analgesics 251
III. Alternative Neural Changes in Morphine-Resistant
Neuropathic Pain States 252
IV. New Drug Therapy for Neuropathic Pain 253
V. Conclusion 256
References 256
CONTENTS xi
Regulated Exocytosis from Astrocytes: Physiological and
Pathological Related Aspects
Corrado Cali, Julie Marchaland, Paola Spagnuolo,
Julien Gremion, and Paola Bezzi
I- Introduction 262
II- Are Astrocytes Specialized Secretory Cells? 263
III- Calcium-Dependent Glutamate Release from Astrocytes is Deregulated
in Pathological Conditions with an Inflammatory Component 280
References 283
Glutamate Release from Astrocytic Gliosomes Under
Physiological and Pathological Conditions
Marco Milanese, Tiziana Bonifacino,
SimoNA Zappettini, Cesare Usai, Carlo Tacchetti,
Mario Nobile, and Giambattista Bonanno
I- New Perspectives in Astrocyte Function 296
II- Gliosomes as a Model to Study Astrocyte Properties 297
III- Exocytotic Release of Glutamate from Gliosomes 301
IV- Glutamate Release Induced by Heterotransporter Activation 308
V- Glutamate Release from Gliosomes in a Mouse Model of Amyotrophic
Lateral Sclerosis 311
VI- Concluding Remarks 313
References 314
Neurotrophic and Neuroprotective Actions of an Enhancer
of Ganglioside Biosynthesis
JlN-ICHI INOKUCHI
1- Introduction 320
II- Development of a Ceramide Analog PDMP 321
III- Effects of L- and D-PDMP on Neurite Extension 323
IV- Facilitation of Functional Synapse Formation and Ganglioside
Synthesis by L-PDMP 324
V- Upregulation of p42 MAPKActivity 326
VI- Improvement of the Spatial Memory Deficit and the Apoptotic
Neuronal Death in Ischemic Rats 326
VII- Effect of l-PDMP on Biosynthesis of Cortical Gangliosides
after Repeated Cerebral Ischemia 329
VIII- Discussion 331
References 333
xii CONTENTS
Involvement of Endocannabinoid Signaling in the Neuroprotective
Effects of Subtype 1 Metabotropic Glutamate Receptor Antagonists
in Models of Cerebral Ischemia
Elisa Landucci, Francesca Boscia, Elisabetta Gerace,
Tania Scartabelli, Andrea Cozzi, Flavio Moroni,
Guido Mannaioni, and Domenico E. Pellegrini-Giampietro
I. Introduction 338
II. Role of mGlu Receptors in CA1 Hippocampal Postischemic
Neuronal Death 339
III. Interactions Between mGlul Receptors and Endocannabinoids
in the CA1 Hippocampal Region 342
IV. Conclusions 345
References 347
NF-kappaB Dimers in the Regulation of Neuronal Survival
Ilenia Sarnico, Annamaria Lanzillotta, Marina Benarese,
Manuela Alghisi, Cristina Baiguera, Leontino Battistin,
PierFranco Spano, and Marina Pizzi
I. Nuclear Factor-kappaB (NF-/sB) in Brain 352
II. p50/RelA and c-Rel-Containing Dimers Elicit Opposite Regulation
of Neuron Vulnerability 354
References 358
Oxidative Stress in Stroke Pathophysiology: Validation
of Hydrogen Peroxide Metabolism as a Pharmacological
Target to Afford Neuroprotection
Diana Amantea, Maria Cristina Marrone, Robert Nistico,
Mauro Federici, Giacinto Bagetta, Giorgio Bernardi,
and Nicola Biagio Mercuri
I. Introduction 364
II. Experimental Procedures 365
III. Results 368
IV. Discussion 370
References 373
CONTENTS xiii
Role of Akt and Erk Signaling in the Neurogenesis
following Brain Ischemia
Norifumi Shioda, Feng Han, and Kohji Fukunaga
I. Introduction 376
II. Stimulation of Endogenous Neural Progenitor Proliferation by
Neurotrophic Factors in the Hippocampus 377
HI. Transplantation of Neural Stem Cells and Gene Therapy in the
Brain Ischemia 378
IV. Cell Signaling to Promote Neurogenesis in the Adult Brain 379
V. Vanadium Compounds are Attractive Therapeutics to Promote
Neurogenesis in Neurodegenerative Disorders 379
VI. Conclusion 382
References 383
Prevention of Glutamate Accumulation and Upregulation of Phospho-Akt
may Account for Neuroprotection Afforded by Bergamot Essential Oil
against Brain Injury Induced by Focal Cerebral Ischemia in Rat
Diana Amantea, Vincenza Fratto, Simona Maida,
DOMENICANTONIO ROTIROTI, SaLVATORE RAGUSA, GlUSEPPE NAPPI,
Giacinto Bagetta, and Maria Tiziana Corasaniti
I. Introduction 390
II. Materials and Methods 391
III. Results 395
IV. Discussion 397
References 403
Identification of Novel Pharmacological Targets to
Minimize Excitotoxic Retinal Damage
rossella russo, domenicantonio rotiroti, cristina tassorelli,
Carlo Nucci, Giacinto Bagetta, Massimo Gilberto Bucci,
Mari Tiziana Corasaniti, and Luigi Antonio Morrone
I. Introduction 408
II. Neurochemical and pharmacological Evidence to Support Excitotoxicity
in the Mechanisms of RGC Death in Experimental Glaucoma 409
III. Blockade of Excitotoxicity Sustains the PI3-K/Akt Prosurvival Pathway
in Retinal Ischemia 414
IV. Conclusions 418
References 418
Index 425
Contents of Recent Volumes 437
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| spelling | Advances in neuropharmacology ed. by Bagetta, G. ... Amsterdam [u.a.] Elsevier 2009 XXVI, 464 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier International review of neurobiology 85 Einzelaufnahme eines Zeitschr.-Bd. Neuropharmacology Neuropharmacology Congresses Neuropharmakologie (DE-588)4041896-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content (DE-588)1071861417 Konferenzschrift gnd-content Neuropharmakologie (DE-588)4041896-0 s b DE-604 Bagetta, Giacinto Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017719027&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| title | Advances in neuropharmacology |
| title_auth | Advances in neuropharmacology |
| title_exact_search | Advances in neuropharmacology |
| title_full | Advances in neuropharmacology ed. by Bagetta, G. ... |
| title_fullStr | Advances in neuropharmacology ed. by Bagetta, G. ... |
| title_full_unstemmed | Advances in neuropharmacology ed. by Bagetta, G. ... |
| title_short | Advances in neuropharmacology |
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