Molecular structure and function of the tight junction: from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany]
Gespeichert in:
| Format: | Tagungsbericht Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boston, Mass.
Blackwell
2009
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
1165 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VIII, 346 S. Ill., graph. Darst. |
| ISBN: | 9781573317498 1573317497 |
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| adam_text | Titel: Molecular structure and function of the tight junction
Autor: Fromm, Michael
Jahr: 2009
Molecular Structure and Function
of the Tight Junction
From Basic Mechanisms to Clinical Manifestations
Editors
Michael Fromm and Jorg-Dieter Schulzke
This volume is the result of a conference, entitled Molecular Structure and Function of the Tight
Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 -27, 2008 at
Harnack House of the Max Planck Society in Berlin, Germany.
CONTENTS
Tight Junctions: Molecular Structure Meets Function. ^Jorg-Dieter Schulzke
and Michael Fromm 1
The Life and Work of Shoichiro Tsukita. By James Melvin Anderson 7
Part I. Molecular Structure of the Tight Junction
Mechanisms of Outside-in Signaling at the Tight Junction by Junctional Adhesion
Molecule A. By Eric A. Severson and Charles A. Parkos 10
The Oligomerization of the Coiled Coil-domain of Occluddin Is Redox Sensitive.
By Juliane K. Walter, Christine Rueckert, Martin Voss, S.L. Mueller, Jorg
Piontek, Klaus Gast, and Ingolf E. Blasig 19
Vertebrate Animal Models Unravel Physiological Roles for Zonula Occludens
Tight Junction Adaptor Proteins. By Walter Hunziker, Tania K. Kiener, and
Jianliang Xu 28
Structure and Function of Extracellular Claudin Domains. By Gerd Krause, Lars
Winkler, Christian Piehl, Ingolf Blasig, Jorg Piontek, and Sebastian L.
Muller 34
Roles of ZO-1 and ZO-2 in Establishment of the Belt-like Adherens and Tight
Junctions with Paracellular Permselective Barrier Function. By Sachiko
Tsukita, Tatsuya Katsuno, Yuji Yamazaki, Kazuaki Umeda, Atsushi Tamura,
and Shoichiro Tsukita 44
Molecular Basis for Cation Selectivity in Claudin-2 Based Pores. By Alan S. L.
Yu 53
v
vl Annals of the New York Academy of Sciences
The Role of Claudin-Based Tight Junctions in Morphogenesis. By Mikio Furuse
and Kazumasa Moriwaki 58
Occludin Phosphorylation in Regulation of Epithelial Tight Junctions. By
Radhakrishna Rao 62
Differential Phosphorylation of Occludin and Tricellulin by CK2 and CK1. By
MaxJ. Dorfel, Julie K. Westphal, and Otmar Huber 69
Part II. Regulation of the Tight Junction and Barrier Function
High-Resolution Analysis of Barrier Function. By Michael Fromm, Susanne M.
Krug, Sebastian Zeissig, Jan F. Richter, Rita Rosenthal, Jorg-Dieter Schulzke,
and Dorothee Giinzel 74
Claudin-2-dependent Changes in Noncharged Solute Flux Are Mediated by the
Extracellular Domains and Require Attachment to the PDZ-scaffold. By
Christina M. Van Itallie, Jennifer Holmes, Arlene Bridges, and James Melvin
Anderson 82
The Tight Junction Protein Cingulin Regulates Gene Expression and RhoA
Signaling. By Sandra Citi, Serge Paschoud, Pamela Pulimeno, Francesco
Timolati, Fabrizio De Robertis, Lionel Jond, and Laurent Guillemot 88
Modification of Tight Junction Structure and Permeability by Nutritional Means.
By James M. Mullin, Sonja M. Skrovanek, and Mary Carmen
Valenzano 99
Zonula Occludens-1 and -2 Are Cytosolic Scaffolds That Regulate the Assembly
of Cellular Junctions. By Alan S. Fanning and James M. Anderson 113
The Tight Junction Protein ZO-2 Blocks Cell Cycle Progression and Inhibits
Cyclin D1 Expression. By Lorenza Gonzalez-Mariscal, Rocio Tapia, Miriam
Huerta, and Esther Lopez-Bayghen 121
Analysis of Claudin Genes in Pediatric Patients with Bartter s Syndrome. By
Yan-Hua Chen, Jen-Jar Lin, Beverly G. Jeansonne, Rodney Tatum, and Qun
Lu 126
Mechanisms of Epithelial Cell Shedding in the Mammalian Intestine and
Maintenance of Barrier Function. By Alastair J.M. Watson, Carrie A.
Duckworth, Yanfang Guan, and Marshall H. Montrose 135
Cysteine Mutagenesis to Study the Structure of Claudin-2 Paracellular Pores. By
Susanne Angelow and Alan S.L. Yu 143
Insights into Driving Forces and Paracellular Permeability from Claudin-16
Knockdown Mouse. By Qixian Shan, Nina Himmerkus, Jianghui Hou,
Daniel A. Goodenough, and Markus Bleich 148
Claudin Function in the Thick Ascending Limb of Henle s Loop. By Dorothee
Giinzel, Lea Haisch, Sandra Pfaffenbach, Susanne M. Krug, Susanne Milatz,
Salah Amasheh, Walter Hunziker, and Dominik Miiller 152
Cadherin-Mediated Regulation of Tight Junctions in Stratifying Epithelia. By
Christian Michels, Saeed Yadranji Aghdam, and Carien M. Niessen 163
Part III. Immune System, Microbes, and the Gastrointestinal Barrier
Tight Junctions and Enteropathogenic E. coll By Andrew W Weflen, Neal M.
Alto, and Gail A. Hecht 169
Contents vii
Modulation of Intestinal Barrier Properties by Probiotics: Role in Reversing
Colitis. By Silvia C. Resta-Lenert and Kim E. Barrett 175
Effect of Probiotics on Intestinal Barrier Function. By Rudolf Mennigen and
Matthias Bruewer 183
Probiotic Therapy in Radiation-Induced Intestinal Injury and Repair. By
Matthew A. Ciorba and William E Stenson 190
Tight Junctions, Intestinal Permeability, and Autoimmunity: Celiac Disease and
Type 1 Diabetes Paradigms. i?yjeroen Visser, Jan Rozing, Anna Sapone,
Karen Lammers, and Alessio Fasano 195
Corticotropin-Releasing Hormone and Mast Cells in the Regulation of Mucosal
Barrier Function in the Human Colon. By Conny Wallon and Johan D.
Soderholm 206
Part TV. Transport and Epithelial Barrier
Tight Junction Proteins as Channel Formers and Barrier Builders: Claudin-2, -5,
and -8. By Salah Amasheh, Susanne Milatz, Susanne M. Krug, Alexander G.
Markov, Dorothee Giinzel, Maren Amasheh, and Michael Fromm 211
Dynamic Regulation of Epithelial Cell Fate and Barrier Function by Intercellular
Junctions. By Stefan Koch and Asma Nusrat 220
Control of the Blood Brain Barrier by Glucocorticoids and the Cells of the
Neurovascular Unit. By Susanne Kroll, Jehad El-Gindi, Gokulan
Thanabalasundaram, Patcharee Panpumthong, Sebastian Schrot, Christoph
Hartmann, and Hans-Joachim Galla 228
Regulation of Intestinal Electroneutral Sodium Absorption and the Brush Border
Na+/H+ Exchanger by Intracellular Calcium. By Nicholas C. Zachos, Olga
Kovbasnjuk, and Mark Donowitz 240
The Role of the NHERF Family of PDZ Scaffolding Proteins in the Regulation of
Salt and Water Transport: Lessons Learned from Knockout Mice. By Ursula
Seidler, Anurag Kumar Singh, Ayhan Cinar, Mingmin Chen, Jutta
Hillesheim, Boris Hogema, and Brigitte Riederer 249
Regulation of the Intestinal Anion Exchanger DRA (Downregulated in
Adenoma). By Georg Lamprecht, Vera Gaco, Jerrold R. Turner, Dorgam
Natour, and Michael Gregor 261
Barrier Effects of Nutritional Factors. By Maren Amasheh, Susanne Andres, Salah
Amasheh, Michael Fromm, andJorg-Dieter Schulzke 267
Pathways of Gliadin Transport in Celiac Disease. By Martine Heyman and
Sandrine Menard 274
A New Insight into Pathophysiological Mechanisms of Zinc in Diarrhea. By Kazi
Mirajul Hoquc, Rafiquel Sarker, Sandra E. Guggino, and Chung-Ming
Tse .7 279
Part V. Inflammation and Gastrointestinal Function
Mechanisms of Diarrhea in Inflammatory Bowel Diseases. By Henry J.
Binder . 285
Epithelial Tight Junctions in Intestinal Inflammation. By Jocrg D. Schulzke,
Svenja Ploeger, Maren Amasheh, Anja Fromm, Sebastian Zeissig, Hanno
Troeger, Jan Richter, Christian Bojarski, Michael Schumann, and Michael
Fromm 294
v » Annals of the New York Academy of Sciences
Mechanisms of Tight Junction Dysregulation in the SAMPl/YitFc Model of
Crohn s Disease-like Ileitis. By Brian K. Reuter and Theresa T.
Pizarro 301
The Role of JAM-A in Inflammatory Bowel Disease: Unrevealing the Ties That
Bind. By Stefania Vetrano and Silvio Danese 308
No Static at All: A New Perspective on Molecular Architecture of the Tight
Junction. By W. Vallen Graham, Amanda M. Marchiando, Le Shen, and
Jerrold R. Turner 314
Lymphoepithelial Interactions: A New Paradigm. By Stephanie Dahan, Franziska
Roth-Walter, Andrea E Martin, Paul Arnaboldi, and Lloyd Mayer 323
Metabolic Stress Evokes Decreases in Epithelial Barrier Function: Mechanistic
Insights from in Vitro and in Vivo Model Systems. By Kimberley Lewis and
Derek M. McKay 327
Enteral versus Parenteral Nutrition: Effect on Intestinal Barrier Function. By Hua
Yang, Yongjia Feng, Xiaoyi Sun, and Daniel H. Teitelbaum 338
The New York Academy of Sciences believes it has a responsibility to provide an open forum for
discussion of scientific questions. The positions taken by the participants in the reported conferences are
their own and not necessarily those of the Academy. The Academy has no intent to influence legislation
by providing such forums.
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| spelling | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] ed. by Michael Fromm ... Boston, Mass. Blackwell 2009 VIII, 346 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 1165 tight junctions Tight junction (DE-588)4342499-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2008 Berlin gnd-content Tight junction (DE-588)4342499-5 s DE-604 Fromm, Michael 1945- Sonstige (DE-588)138547351 oth Conference Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations 2008 Berlin Sonstige (DE-588)6526219-0 oth New York Academy of Sciences Annals of the New York Academy of Sciences 1165 (DE-604)BV002532608 1165 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017706288&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] tight junctions Tight junction (DE-588)4342499-5 gnd |
| subject_GND | (DE-588)4342499-5 (DE-588)1071861417 |
| title | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] |
| title_auth | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] |
| title_exact_search | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] |
| title_full | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] ed. by Michael Fromm ... |
| title_fullStr | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] ed. by Michael Fromm ... |
| title_full_unstemmed | Molecular structure and function of the tight junction from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] ed. by Michael Fromm ... |
| title_short | Molecular structure and function of the tight junction |
| title_sort | molecular structure and function of the tight junction from basic mechanisms to clinical manifestations result of a conference entitled molecular structure and function of the tight junction from basic mechanisms to clinical manifestations held on april 25 27 2008 in berlin germany |
| title_sub | from basic mechanisms to clinical manifestations ; [result of a Conference, Entitled Molecular Structure and Function of the Tight Junction: From Basic Mechanisms to Clinical Manifestations, held on April 25 - 27, 2008 ... in Berlin, Germany] |
| topic | tight junctions Tight junction (DE-588)4342499-5 gnd |
| topic_facet | tight junctions Tight junction Konferenzschrift 2008 Berlin |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017706288&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002532608 |
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