Bibliographische Detailangaben

Format:	Buch
Sprache:	English
Veröffentlicht:	New York, NY Humana Press 2009
Schriftenreihe:	Methods in molecular biology 525
Schlagworte:	Immunoglobulins / Therapeutic use Antibodies, Monoclonal / therapeutic use Immunotherapy / methods Anticorps Antibodies, Monoclonal > therapeutic use Immunoglobulins > Therapeutic use Immunotherapy > methods
Beschreibung:	Includes bibliographical references and index Therapeutic antibodies: current state and future trends - is a paradigm change coming soon? / D.S. Dimitrov and J.D. Marks -- Preparation of recombinant viral glycoproteins for novel and therapeutic antibody discovery / Y.P. Chan ... [et al.] -- Design of a human synthetic combinatorial library of single-chain antibodies / L. Nahary and I. Benhar -- Construction of a human antibody domain (V(H)) library / W. Chen ... [et al.] -- Generation and selection of rabbit antibody libraries by phage display / C. Rader -- Construction of a large naive human phage-displayed Fab library through one-step cloning / Z. Zhu and D.S. Dimitrov -- Identification of target and function specific antibodies for effective drug delivery / Y. Zhou and J.D. Marks -- Screening of specific internalization Fab fragment from human naive phage library by combinational bio-panning / X. Wang and B.B. Cao -- Competitive antigen panning for selection of HIV-1 neutralizing human monoclonal antibodies specific for gp41 / M.Y. Zhang and D.S. Dimitrov -- Selection of non-aggregating V(H) binders from synthetic V(H) phage-display libraries / M. Arbabi-Ghahroudi, R. Mackenzie and J. Tanha -- Isolation of full-length IgG antibodies from combinatorial libraries expressed in Escherichia coli / Y. Mazor ... [et al.] -- Multiplexed flow cytometry: high-throughput screening of single-chain antibodies / J. Ayriss ... [et al.] -- Human antibody repertoires / P.J. Meijer ... [et al.] -- Rapid screening platform for stabilization of scFvs in Escherichia coli / B.R. Miller, S.M. Glaser and S.J. Demarest -- In vitro antibody affinity maturation targeting germline hotspots / M. Ho and I. Pastan -- Affinity maturation by phage display / H. Thie ... [et al.] -- Production of chimeric heavy-chain antibodies / J. Zhang, R. Mackenzie and Y. Durocher -- Mammalian cell display for antibody engineering / M. Ho and I. Pastan -- Improving antibody binding affinity and specificity for therapeutic development / J. Bostrom ... [et al.] -- Construction and production of an IgG-like tetravalent bispecific antibody for enhanced therapeutic efficacy / D. Lu and Z. Zhu -- Deimmunization of monoclonal antibodies / T.D. Jones ... [et al.] -- Anti-CD22 onconase: preparation and characterization / D.L. Newton, L.H. Stockwin and S.M. Rybak -- Antibody-cytotoxic agent conjugates: preparation and characterization / R. Singh and H.K. Erickson -- High-level production of a humanized immunoRNase fusion protein from stably transfected myeloma cells / J. Krauss ... [et al.] -- Antibody fragment expression and purification / D. Dimitrova, V. Choudhry and C.C. Broder -- Scaling-up and production of therapeutic antibodies for preclinical studies / Y. Feng and D.S. Dimitrov -- Antibody production by the gram-positive bacterium Bacillus megaterium / E. Jordan ... [et al.] -- Neutralization of HIV by antibodies / I. Prado, T.R. Fouts and A.S. Dimitrov -- Dynamics of antibody domains studied by solution NMR / B.K. Vu ... [et al.] -- In vivo method for establishing synergy between antibodies to epidermal growth factor receptor and vascular endothelial growth factor receptor-2 / J.R. Tonra ... [et al.] -- Passive immunization with human neutralizing monoclonal antibodies against HIV-1 in macaque models: experimental approaches / R.M. Ruprecht -- Organizing, exploring, and analyzing antibody sequence data: the case for relational-database managers / J. Owens
Beschreibung:	xviii, 585 p., [8] p. of plates Ill., graph. Darst. 27 cm