Thyroidhormon und die finale Differenzierung von Haarsinneszellen:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Abschlussarbeit Buch |
| Sprache: | German |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 43, [59] S. Ill., graph. Darst. 21 cm |
Internformat
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| 245 | 1 | 0 | |a Thyroidhormon und die finale Differenzierung von Haarsinneszellen |c von Niels Brandt |
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Datensatz im Suchindex
| _version_ | 1804138879810273280 |
|---|---|
| adam_text | Titel: Thyroidhormon und die finale Differenzierung von Haarsinneszellen
Autor: Brandt, Niels
Jahr: 2009
Inhaltsverzeichnis
. SUMMARY..
II. ZUSAMMENFASSUNG..
1. EINLEITUNG______________________________________________________________________5
1.1 Die Cochlea........................................................................................................................................5
1.2 Die Haars inneszellen........................................................................................................................6
1.2.1 Innere Haarsinneszellen..............................................................................................................7
1.2.2 Äußere Haarsinneszellen............................................................................................................8
1.3 Entwicklung der Ionenströme in Haarsinneszellen.....................................................................8
1.3.1 Innere Haarsinneszellen und Spontanaktivität...........................................................................8
1.3.2 Äußere Haarsinneszellen und cochleärer Verstärker..............................................................12
1.4 THYROIOHOBMON UND SEIN ElNFLUSS AUF DIE INNENOHRENTWICKLUNG.............................................16
1.4.1 ThyrokJhormon...........................................................................................................................16
1.4.2 Einfluss von Thyroidhormon auf die Innenohrentwicklung......................................................17
1.5 Fragestellung.................................................................................................................................20
2. ERGEBNISSE......................................................................................................................__________23
2.1 THYROID HORMONE DEFICIENCY AFFECTS POSTNATAL SPIKING ACTIVITY AND EXPRESSION OF CA2* AND
K* CHANNELS IN RODENT INNER HAIR CELLS...............................................................................................23
2.2 Deafness in TRh-mutants: New findings from HAIR CELL-SPECIFIC GENE DELETION.....................24
2.3 Persistence of Cav1 .3 Ca2* Channels in matuhe outer hair cells Supports outer hair cell
afferent sk3naling.................................................................................................................................25
3. DISKUSSION_____________________________________________________________________27
4. REFERENZEN____________________________________________________________________33
5. EIGENANTEIL____________________________________________________________________41
6. ANHANG________________________________________________________________________43
6.1 Brandt N, Kuhn S, Münkner S, Braig C, Winter H, Blin N, Vonthein R, Knipper M, Engel J.
Thyroid hormone defkaency affects postnatal spiking activity and expression ol Ca2* and K* Channels
in rodent inner hair cells.
J Neurosci. 2007 Mar 21 ;27(12):3174-86.
6.2 Winter H, Rüttiger L, Müller M, Kuhn S, Brandt N, Zimmermann U, Sausbier M, Conscience A, Hirt
B, Flamant F, Tian Y, Zuo J, Bress A, Pfister M, Ruth P, Löwenheim H, Samarut J, Engel J, Knipper
M.
Deafness in TRß-mutants: New findings from hair cell-speöfic gene deletion.
Unter positiver Begutachtung (Revision) bei J. Neuroscience.
6.3 Knirsch M, Brandt N, Braig C, Kuhn S, Hirt B, Münkner S, Knipper M, Engel J.
Persistence of Cay1.3 Ca2* Channels in mature outer hair cells Supports outer hair cell afferent
signaling.
J Neurosci. 2007 Jun 1327(24):6442-51.
6.4 Lebenslauf und Bildungsgang
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| title | Thyroidhormon und die finale Differenzierung von Haarsinneszellen |
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