Mesenchymal stem cells for the heart: from bench to bedside
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hangzhou
Zhejiang Univ. Press [u.a.]
2009
|
| Schriftenreihe: | Advanced topics in science and technology in China
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | IX, 113 S. Ill., graph. Darst. |
| ISBN: | 9787308061674 9783540881490 9783540881506 |
Internformat
MARC
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|---|---|---|---|
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| 020 | |a 9787308061674 |9 978-7-308-06167-4 | ||
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| 245 | 1 | 0 | |a Mesenchymal stem cells for the heart |b from bench to bedside |c ed. by Jian'an Wang ... |
| 264 | 1 | |a Hangzhou |b Zhejiang Univ. Press [u.a.] |c 2009 | |
| 300 | |a IX, 113 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Advanced topics in science and technology in China | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-017170225 | ||
Datensatz im Suchindex
| _version_ | 1804138692585979904 |
|---|---|
| adam_text | Contents
1
MSCs Isolation and Culture Ex Vivo
..................... 1
1.1
Cell Isolation
.......................................... 2
1.1.1
Direct Adherence Method
......................... 3
1.1.2
Density Gradient Centrifugation
.................... 3
1.1.3
Magnetic Microbead or Plow Cytometry Method
..... 6
1.2
Cell Culture
............................. .............. 7
1.2.1
Materials
...............................,........ ?
1.2.2
Procedures
...................................... 7
.1.3
Cell Gryopreservation and Thawing
....................... 8
1.3.1
Materials
........................................ 9
1.3.2
Procedures
...................................... 9
References
................................................. 9
2
MSCs Identification
___.................................. 12
2.1
Minimal Criteria
................,....................... 13
2.2
Sonic
Commente
of the Criteria
.......................... 13
2.3
Other Methods
......................................... 14
2.3.1
Morphology Characteristics
........................ 14
2.3.2
Other Markers
................................... 14
2.4
Conclusion
............................................ 15
References
................................................. 16
3
Biological Characteristics of MSCs
....................... 17
3.1
Surface Markers and Paracrine Characteristics
.....,....... 18
3.1.1
Surface Markers
.................................. 18
3.1.2
Paracrine Characteristics of MSCs
.................. 20
3.2
Efcetrophysiologieal Properties of MSCs and Their Electric
Coupling with
Cardiömyocytes
........................... 21
3.2.1
Characterization of Ion Channels in MSCs
........... 21
3.2.2
Why Does an. Individual Cell Express Different
Currents?
.......-----................,........... 26
VIII Contents
3.2.3
Electric
Coupling of MSCs with Host Cardiomyocytes
. 25
3.3
Proliferation of MSCs and Teloinerase Properties
........... 29
3.3.1
Structure and Function of Telomeres and Telomerase
. 30
3.3.2
Telomere and Telomerase in MSCs
................. 30
3.4
Multilineage Transdifferentiation of MSCs
................. 32
3.4.1
MSCs and Cardiomyogenesis
....................... 33
3.4.2
Differentiation Fate of MSCs
....................... 36
3.5
Immunological Characteristics of MSCs
................... 37
3.5.1
Immunological Characteristics of MSCs
............. 38
3.5.2
In vivo Studies
................................... 43
3.5.3
Immune-related Properties of MSCs in Cardiology
.... 44
3.6
Conclusion
............................................ 45
References
................................................. 45
4
Utilization of MSCs for Repairing Cardiomyocytes
....... 57
4.1
Application of MSCs on Myocardial Infarction
............. 59
4.2
Application of MSCs on Cardiomyopathy and Chronic Heart
Failure
................................................ 63
4.3
Conclusion
............................................ 65
References
................................................. 66
5
Current Status of MSCs in Clinical Application
.......... 71
5.1
The Type and Number of Transplanted Cells
.............. 77
5.2
Cell Preparation
........................................ 78
5.3
The Time Point and Pathway of Cell Transplantation
....... 78
5.4
Others
................................................ 79
5.5
Conclusion
............................................ 81
References
................................................. 81
6
MSCs as a Vector of Gene Engineering
................... 85
6.1
Adenoviruses and Angiogenesis-related Genes
.............. 87
6.2
Adeno-associated Virus (AAV) and Anti-inflammation
Related Genes
......................................... 88
6.3
Retrovirus
and Anti-apoptosis Related Genes
.............. 89
6.4
Lentivirus and Pacemaker Current Gene
................... 90
6.5
Conclusion
............................................ 91
References
................................................. 91
7
Feasibility of MSCs Transplantaion
....................... 94
7.1
General Ethical Considerations
........................... 95
7.2
Safety Issues
........................................... 95
7.3
Informed Consent
......... ............................. 97
7.4
Conclusion
............................................ 97
References
................................................. 98
Contents
IX
8
Status
and Expectation of MSCs Therapy
................ 99
8.1
Clinical Application and Outcomes
.......................100
8.2
Mechanism of Therapeutic Effects
........................102
8.3
Expectations with MSCs Therapy
........................103
References
.................................................105
Index
.........................................................109
|
| any_adam_object | 1 |
| author_GND | (DE-588)138836108 |
| building | Verbundindex |
| bvnumber | BV035366263 |
| classification_rvk | YB 8703 |
| ctrlnum | (OCoLC)635335841 (DE-599)DNB990669114 |
| dewey-full | 616.106 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.106 |
| dewey-search | 616.106 |
| dewey-sort | 3616.106 |
| dewey-tens | 610 - Medicine and health |
| discipline | Maschinenbau / Maschinenwesen Medizin |
| format | Book |
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| id | DE-604.BV035366263 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T21:32:14Z |
| institution | BVB |
| isbn | 9787308061674 9783540881490 9783540881506 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-017170225 |
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| physical | IX, 113 S. Ill., graph. Darst. |
| publishDate | 2009 |
| publishDateSearch | 2009 |
| publishDateSort | 2009 |
| publisher | Zhejiang Univ. Press [u.a.] |
| record_format | marc |
| series2 | Advanced topics in science and technology in China |
| spelling | Mesenchymal stem cells for the heart from bench to bedside ed. by Jian'an Wang ... Hangzhou Zhejiang Univ. Press [u.a.] 2009 IX, 113 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advanced topics in science and technology in China Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd rswk-swf Stammzelle (DE-588)4665329-6 gnd rswk-swf Mesenchymzelle (DE-588)4278308-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Kardiovaskuläre Krankheit (DE-588)4024666-8 s Mesenchymzelle (DE-588)4278308-2 s Stammzelle (DE-588)4665329-6 s DE-604 Wang, Yi Sonstige (DE-588)138836108 oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017170225&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Mesenchymal stem cells for the heart from bench to bedside Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Stammzelle (DE-588)4665329-6 gnd Mesenchymzelle (DE-588)4278308-2 gnd |
| subject_GND | (DE-588)4024666-8 (DE-588)4665329-6 (DE-588)4278308-2 (DE-588)4143413-4 |
| title | Mesenchymal stem cells for the heart from bench to bedside |
| title_auth | Mesenchymal stem cells for the heart from bench to bedside |
| title_exact_search | Mesenchymal stem cells for the heart from bench to bedside |
| title_full | Mesenchymal stem cells for the heart from bench to bedside ed. by Jian'an Wang ... |
| title_fullStr | Mesenchymal stem cells for the heart from bench to bedside ed. by Jian'an Wang ... |
| title_full_unstemmed | Mesenchymal stem cells for the heart from bench to bedside ed. by Jian'an Wang ... |
| title_short | Mesenchymal stem cells for the heart |
| title_sort | mesenchymal stem cells for the heart from bench to bedside |
| title_sub | from bench to bedside |
| topic | Kardiovaskuläre Krankheit (DE-588)4024666-8 gnd Stammzelle (DE-588)4665329-6 gnd Mesenchymzelle (DE-588)4278308-2 gnd |
| topic_facet | Kardiovaskuläre Krankheit Stammzelle Mesenchymzelle Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017170225&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT wangyi mesenchymalstemcellsfortheheartfrombenchtobedside |