HPV infection and cancers of the skin: diagnostics and therapy
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Bremen ; London ; Boston
UNI-MED-Verl.
2008
|
| Ausgabe: | 1st ed. |
| Schriftenreihe: | UNI-MED science
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | 172 S. zahlr. Ill., graph. Darst. 25 cm |
| ISBN: | 9783837410761 9781848151376 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV035329078 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | t | ||
| 008 | 090224s2008 ad|| |||| 00||| eng d | ||
| 015 | |a 09,A08,1025 |2 dnb | ||
| 016 | 7 | |a 992053757 |2 DE-101 | |
| 020 | |a 9783837410761 |c (Bremen) Pp. : EUR 39.80 |9 978-3-8374-1076-1 | ||
| 020 | |a 9781848151376 |c (London ...) Pp. |9 978-1-84815-137-6 | ||
| 035 | |a (OCoLC)304401021 | ||
| 035 | |a (DE-599)DNB992053757 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-19 |a DE-578 | ||
| 050 | 0 | |a RC168.P15 | |
| 082 | 0 | |a 616.99477 |2 22/ger | |
| 084 | |a QW 165.5 |2 nlm | ||
| 084 | |a 610 |2 sdnb | ||
| 245 | 1 | 0 | |a HPV infection and cancers of the skin |b diagnostics and therapy |c [Ulrich R. Hengge. In collab. with Jens Bichel ...] |
| 250 | |a 1st ed. | ||
| 264 | 1 | |a Bremen ; London ; Boston |b UNI-MED-Verl. |c 2008 | |
| 300 | |a 172 S. |b zahlr. Ill., graph. Darst. |c 25 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a UNI-MED science | |
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Hautkrebs - Humanes Papillomavirus | |
| 650 | 4 | |a Papillomaviruses | |
| 650 | 0 | 7 | |a Humanes Papillomavirus |0 (DE-588)7643765-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Hautkrebs |0 (DE-588)4140169-4 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Hautkrebs |0 (DE-588)4140169-4 |D s |
| 689 | 0 | 1 | |a Humanes Papillomavirus |0 (DE-588)7643765-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Hengge, Ulrich R. |d 1963- |e Sonstige |0 (DE-588)121909735 |4 oth | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017133535&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-017133535 | ||
Datensatz im Suchindex
| _version_ | 1804138640594436096 |
|---|---|
| adam_text | Titel: HPV infection and cancers of the skin
Autor: Hengge, Ulrich R.
Jahr: 2008
10 Contents
Inhaltsverzeichnis
m Human Papillomavirus (HPV) - Immunology 16
1.1. Hypotheses, Problems and Solutions 16
1.2. Humoral Immunity 17
1.3. Mucosal Immunity 18
1.4. Cellular Immunity 18
1.5. Induction Phase: Dendritic Cells (DC) and T-Helper (Th) Cells 20
1.6. Effector Mechanisms: Cytotoxic T-Cells (Tc), DTH and Cytokines 20
1.7. Induction of Tolerance and Latency 20
1.8. Immunological Basis for HPVVaccination 21
1.9. HPV - Outlook 21
1.10. References 21
^J HPV - Taxonomy and Virology 24
2.1. Structure and Taxonomy 24
2.2. Viral Life Cycle 27
2.3. Viral Oncogenesis 28
2.4. References 31
^| Diagnostic Tests for HPV-lnfection 36
3.1. Significance of HPV-Testing 36
3.2. Methods for HPV Detection 36
3.3. Clinical Diagnosis of HPV-lnfection 37
3.4. Detection of HPV Antibodies 37
3.5. Detection of Viral Components 38
3.6. Detection of HPV-DNA 38
3.7. Hybridization Techniques 38
3.8. Amplification Techniques 39
3.9. PCR Analysis of Genital Tissue Samples 40
3.10. PCR Analysis of Cutaneous Tissue Samples 40
3.11. HPV-Typing 41
3.12. Direct Sequencing of PCR Products 41
3.13. Restriction Fragment Length Polymorphism (RFLP) of PCR Products 41
3.14. HPV-Type-Specific Probing 42
3.15. HPV-DNA Quantification 43
3.16. HPV Transcript Analysis 43
3.17. Outlook 44
3.18. References 44
^| HPV-lnfection in Organ Transplant Recipients and HIV-Patients 50
4.1. Innate and Acquired Immunity 50
4.2. Infection with HPV 50
4.3. Mechanisms of Infection and Immune Evasion 51
Contents 11
4.4. Treatment of Immunosuppressed Patients with Viral Infections 52
4.4.1. HIV-Patients 52
4.4.2. Anal Intraepithelial Neoplasia 55
4.4.3. Squamous Intraepithelial Lesions 57
4.4.4. Organ Transplant Recipients 57
4.5. HPV and Tumor Development 58
4.6. HPV Persistence 59
4.7. Treatment of Precursor Lesions and Epithelial Tumors in Immunosuppressed Patients 59
4.8. Summary 62
4.9. References 62
m Spectrum of HPV-lnfection in Gynecology 68
5.1. HPV 68
5.2. Classification and Localization 68
5.3. Anogenital Warts 68
5.3.1. Etiology 68
5.3.2. Diagnostics and Morphology 68
5.3.3. Therapy of Anogenital Warts 70
5.4. Precancerous Lesions in Women 70
5.4.1. Etiology 70
5.4.2. Diagnostics and Terminology 70
5.4.3. Natural Course of Cervical HPV-lnfection and HPV-Detection 73
5.4.4. Symptoms 74
5.4.5. Therapy 75
5.4.6. Special Clinical Features 75
5.4.6.1. Bowenoid Papulosis/Bowen s Disease 75
5.4.6.2. Giant Condyloma 75
5.5. Cervical Cancer 76
5.5.1. Epidemiology 76
5.5.2. Etiology 76
5.5.3. Morphology 76
5.5.4. Diagnostics 77
5.5.5. Therapy 77
5.6. References 77
[H Spectrum of HPV-lnfection in Urology 80
6.1. Epidemiology 80
6.2. Pathogenesis 8^
6.3. Classification and Clinical Manifestation 81
6.4. Diagnostic Tests 82
6.5. Differential Diagnoses 84
6.6. Prognosis 84
6.7. Therapy 84
6.8. Summary 84
6.9. References 85
12 Contents
^| Immune Response Modifiers (IRM) - a New Class of Drugs in Dermatology 88
7.1. Recent Data on Mode of Action of Imiquimod 91
7.1.1. Relevance of Plasmacytoid DC 91
7.1.2. Induction of Apoptosis 92
7.1.3. Adjuvant Properties of Imiquimod 92
7.2. References 93
^| Imiquimod in the Treatment of Anogenital Warts 96
8.1. Recommended Patient Treatments 97
8.2. Recommended Physician Treatments 100
8.3. Novel and Not Generally Recommended Therapies 103
8.4. Therapeutic Challenges 105
8.5. References 107
m Imiquimod in the Treatment of Cutaneous Warts and Mollusca 112
9.1. Common Warts 112
9.2. Mollusca Contagiosa 115
9.3. References 115
^| Imiquimod for the Treatment of Actinic Keratoses 118
10.1. Actinic Keratoses 118
10.1.1. Recurrence Rates 120
10.1.2. Mode of Action Studies 120
10.1.3. Comparative Trials for the Treatment of Actinic Keratoses 120
10.2. Bowen s disease 121
10.3. References 121
m Imiquimod in the Treatment of Superficial Basal Cell Cancer 126
11.1. Basal Cell Cancer 126
11.2. Recurrences 128
11.3. Molecular Effects of Imiquimod in Basal Cell Cancer 129
11.4. References 130
J^^ Imiquimod and Melanocytic Skin Tumors 132
12.1. LentigoMaligna 132
12.2. Other Melanocytic Lesions 132
12.2.1. Melanoma Metastases 133
12.3. References 133
[I HPV in the Treatment of Diseases of the Oral Cavity 136
13.1. HPV and Normal Oral Mucosa 136
13.2. Cause of Oral HPV-lnfection 138
13.3. Diseases with Confirmed HPV Etiology 138
13.3.1. Squamous Cell Papilloma 138
13.3.2. Condyloma 138
13.3.3. Common Wart 139
13.3.4. Focal Epithelial Hyperplasia (Heck s Disease) 139
Contents 13
13.3.5. Bowenoid Papulosis 140
13.3.6. Other Lesions with Suspected HPV Etiology 140
13.4. HPV and Oral Precancerous Lesions 141
13.4.1. Leukoplakia 141
13.4.2. Erythroplakia 141
13.5. HPV and Oral Carcinoma 141
13.5.1. Case-Control Studies in Oral Carcinoma 142
13.5.2. Verrucous Carcinoma 143
13.5.3. Experimental Studies on HPV and Oral Carcinoma 143
13.6. Conclusions 144
13.7. References 144
^| Different immune Responses Against Epidermodysplasia Verruciformis
(EV)-Causing HPV 152
14.1. Predisposition and Immunology of EV HPV 152
14.2. Distribution of EV HPV 153
14.3. EVHPVin Skin Tumors of Immunosuppressed and Immunocompetent Patients 154
14.4. Role of EVHPVin Non-Malignant Tumors 154
14.5. EV HPV in Psoriasis 154
14.5.1. EV HPV-Specific Immune Responses in Psoriasis 155
14.5.2. Potential Role of EV HPV in Immunopathogenesis of Psoriasis 155
14.5.3. Causes for Divergent Immune Responses Against EV HPV Antigens in Psoriasis and EV 156
14.5.4. Psoriasis and Skin Cancer 157
14.5.5. Therapeutic Strategies Against Psoriasis and EV 157
14.6. References 157
^| HPVVaccination 162
15.1. HPV Vaccines 162
15.2. Studies on Prophylactic HPV Vaccination 162
15.3. Current CDC Recommendations 164
15.4. Open Questions Referring to Prophylactic HPV Vaccination 165
15.5. Expectations with Regard to HPV Vaccination Programs 165
15.6. References 166
^ Index 180
|
| any_adam_object | 1 |
| author_GND | (DE-588)121909735 |
| building | Verbundindex |
| bvnumber | BV035329078 |
| callnumber-first | R - Medicine |
| callnumber-label | RC168 |
| callnumber-raw | RC168.P15 |
| callnumber-search | RC168.P15 |
| callnumber-sort | RC 3168 P15 |
| callnumber-subject | RC - Internal Medicine |
| ctrlnum | (OCoLC)304401021 (DE-599)DNB992053757 |
| dewey-full | 616.99477 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99477 |
| dewey-search | 616.99477 |
| dewey-sort | 3616.99477 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 1st ed. |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01799nam a2200469 c 4500</leader><controlfield tag="001">BV035329078</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">090224s2008 ad|| |||| 00||| eng d</controlfield><datafield tag="015" ind1=" " ind2=" "><subfield code="a">09,A08,1025</subfield><subfield code="2">dnb</subfield></datafield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">992053757</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783837410761</subfield><subfield code="c">(Bremen) Pp. : EUR 39.80</subfield><subfield code="9">978-3-8374-1076-1</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781848151376</subfield><subfield code="c">(London ...) Pp.</subfield><subfield code="9">978-1-84815-137-6</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)304401021</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DNB992053757</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-19</subfield><subfield code="a">DE-578</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC168.P15</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.99477</subfield><subfield code="2">22/ger</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">QW 165.5</subfield><subfield code="2">nlm</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">610</subfield><subfield code="2">sdnb</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">HPV infection and cancers of the skin</subfield><subfield code="b">diagnostics and therapy</subfield><subfield code="c">[Ulrich R. Hengge. In collab. with Jens Bichel ...]</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">1st ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Bremen ; London ; Boston</subfield><subfield code="b">UNI-MED-Verl.</subfield><subfield code="c">2008</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">172 S.</subfield><subfield code="b">zahlr. Ill., graph. Darst.</subfield><subfield code="c">25 cm</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">UNI-MED science</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Literaturangaben</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hautkrebs - Humanes Papillomavirus</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Papillomaviruses</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Humanes Papillomavirus</subfield><subfield code="0">(DE-588)7643765-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Hautkrebs</subfield><subfield code="0">(DE-588)4140169-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Hautkrebs</subfield><subfield code="0">(DE-588)4140169-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Humanes Papillomavirus</subfield><subfield code="0">(DE-588)7643765-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hengge, Ulrich R.</subfield><subfield code="d">1963-</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)121909735</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HBZ Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017133535&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-017133535</subfield></datafield></record></collection> |
| id | DE-604.BV035329078 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T21:31:24Z |
| institution | BVB |
| isbn | 9783837410761 9781848151376 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-017133535 |
| oclc_num | 304401021 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-578 |
| owner_facet | DE-19 DE-BY-UBM DE-578 |
| physical | 172 S. zahlr. Ill., graph. Darst. 25 cm |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | UNI-MED-Verl. |
| record_format | marc |
| series2 | UNI-MED science |
| spelling | HPV infection and cancers of the skin diagnostics and therapy [Ulrich R. Hengge. In collab. with Jens Bichel ...] 1st ed. Bremen ; London ; Boston UNI-MED-Verl. 2008 172 S. zahlr. Ill., graph. Darst. 25 cm txt rdacontent n rdamedia nc rdacarrier UNI-MED science Literaturangaben Hautkrebs - Humanes Papillomavirus Papillomaviruses Humanes Papillomavirus (DE-588)7643765-6 gnd rswk-swf Hautkrebs (DE-588)4140169-4 gnd rswk-swf Hautkrebs (DE-588)4140169-4 s Humanes Papillomavirus (DE-588)7643765-6 s DE-604 Hengge, Ulrich R. 1963- Sonstige (DE-588)121909735 oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017133535&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | HPV infection and cancers of the skin diagnostics and therapy Hautkrebs - Humanes Papillomavirus Papillomaviruses Humanes Papillomavirus (DE-588)7643765-6 gnd Hautkrebs (DE-588)4140169-4 gnd |
| subject_GND | (DE-588)7643765-6 (DE-588)4140169-4 |
| title | HPV infection and cancers of the skin diagnostics and therapy |
| title_auth | HPV infection and cancers of the skin diagnostics and therapy |
| title_exact_search | HPV infection and cancers of the skin diagnostics and therapy |
| title_full | HPV infection and cancers of the skin diagnostics and therapy [Ulrich R. Hengge. In collab. with Jens Bichel ...] |
| title_fullStr | HPV infection and cancers of the skin diagnostics and therapy [Ulrich R. Hengge. In collab. with Jens Bichel ...] |
| title_full_unstemmed | HPV infection and cancers of the skin diagnostics and therapy [Ulrich R. Hengge. In collab. with Jens Bichel ...] |
| title_short | HPV infection and cancers of the skin |
| title_sort | hpv infection and cancers of the skin diagnostics and therapy |
| title_sub | diagnostics and therapy |
| topic | Hautkrebs - Humanes Papillomavirus Papillomaviruses Humanes Papillomavirus (DE-588)7643765-6 gnd Hautkrebs (DE-588)4140169-4 gnd |
| topic_facet | Hautkrebs - Humanes Papillomavirus Papillomaviruses Humanes Papillomavirus Hautkrebs |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017133535&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT henggeulrichr hpvinfectionandcancersoftheskindiagnosticsandtherapy |