The genetical Factor in endemic goiter:
Gespeichert in:
1. Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Washington
Carnegie Inst.
1932
|
Schriftenreihe: | Papers of the Department of Genetics
37 Publication 428 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | IV, 56 S. Ill. |
Internformat
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650 | 4 | |a Genetics, Medical | |
650 | 4 | |a Goiter, Endemic |x genetics | |
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adam_text | THE GENETICAL FACTOR IN
ENDEMIC GOITER
Carnegie/Biic
T EPOSITUDO
IGNAT: ;JS OOL:
VALKFNBURG I
CARNEGIE INSTITUTION OF WASHINGTON
CONTENTS
I STATEMENT OF PROBLEM 1
1 Introduction 1
2 Earlier studies 1
3 Definition of goiter 5
4 The essential nature of thyroid enlargement in simple goiter 8
5 Causes of endemic goiter, especially exogenous causes 8
II MATERIALS AND METHODS 11
III RESULTS 12
1 Geographic distribution of cases 12
2 Sex incidence 13
3 Age at incidence of goiter 13
4 Stature in relation to goiter 14
5 Build in relation to goiter 16
6 Pulse rate in relation to goiter 17
7 The occurrence of goitrous children in the various matings 17
IV HYPOTHESES AND THEIR TESTING 19
Father and mother both goitrous (Table 8) 23
Father goitrous Mother non-goitrous with goitrous near kin (Table 9) 23
Father goitrous Mother non-goitrous, her near kin non-goitrous (Table 10) 23
Father goitrous Mother non-goitrous, her near kin unknown (Table 11) 23
Father non-goitrous with goitrous near kin Mother goitrous (Table 12) 24
Father non-goitrous; near kin non-goitrous Mother goitrous (Table 13) 26
Father non-goitrous; near kin unknown Mother goitrous (Table 14) 27
Both parents and all of their close relatives believed to be non-goitrous (Table 15) 29
Father and his close relatives free of goiter Mother without goiter; sibs or parents
goitrous (Table 16) 30
Father non-goitrous but with affected sibs or parents Mother normal, with unaf
fected parents (Table 17) 30
Father non-goitrous, but with affected close relatives Mother without goiter, but
with affected close relatives (Table 18) 32
Father non-goitrous; sibs or parents goitrous Mother non-goitrous; sibs and
parents unknown (Table 19) 33
Father non-goitrous, his siblings and parents unknown Mother non-goitrous; her
siblings and parents unaffected (Table 20) 35
Father non-goitrous; sibs and parents unknown Mother non-goitrous; sibs and
parents with goiter (Table 21) 36
Father and mother non-goitrous; their relatives unknown (Table 22) 37
V SUMMARY OF FINDINGS AND CONCLUSIONS 39
VI DISCUSSION 43
APPENDIX: DESCRIPTION OF PEDIGREE CHARTS 45
BIBLIOGRAPHY 55
PEDIGREE CHARTS 56
iii
|
adam_txt |
THE GENETICAL FACTOR IN
ENDEMIC GOITER
Carnegie/Biic
T'EPOSITUDO
IGNAT: ;JS OOL:
VALKFNBURG I
CARNEGIE INSTITUTION OF WASHINGTON
CONTENTS
I STATEMENT OF PROBLEM 1
1 Introduction 1
2 Earlier studies 1
3 Definition of goiter 5
4 The essential nature of thyroid enlargement in simple goiter 8
5 Causes of endemic goiter, especially exogenous causes 8
II MATERIALS AND METHODS 11
III RESULTS 12
1 Geographic distribution of cases 12
2 Sex incidence 13
3 Age at incidence of goiter 13
4 Stature in relation to goiter 14
5 Build in relation to goiter 16
6 Pulse rate in relation to goiter 17
7 The occurrence of goitrous children in the various matings 17
IV HYPOTHESES AND THEIR TESTING ' 19
Father and mother both goitrous (Table 8) 23
Father goitrous Mother non-goitrous with goitrous near kin (Table 9) 23
Father goitrous Mother non-goitrous, her near kin non-goitrous (Table 10) 23
Father goitrous Mother non-goitrous, her near kin unknown (Table 11) 23
Father non-goitrous with goitrous near kin Mother goitrous (Table 12) 24
Father non-goitrous; near kin non-goitrous Mother goitrous (Table 13) 26
Father non-goitrous; near kin unknown Mother goitrous (Table 14) 27
Both parents and all of their close relatives believed to be non-goitrous (Table 15) 29
Father and his close relatives free of goiter Mother without goiter; sibs or parents
goitrous (Table 16) 30
Father non-goitrous but with affected sibs or parents Mother normal, with unaf
fected parents (Table 17) 30
Father non-goitrous, but with affected close relatives Mother without goiter, but
with affected close relatives (Table 18) 32
Father non-goitrous; sibs or parents goitrous Mother non-goitrous; sibs and
parents unknown (Table 19) 33
Father non-goitrous, his siblings and parents unknown Mother non-goitrous; her
siblings and parents unaffected (Table 20) 35
Father non-goitrous; sibs and parents unknown Mother non-goitrous; sibs and
parents with goiter (Table 21) 36
Father and mother non-goitrous; their relatives unknown (Table 22) 37
V SUMMARY OF FINDINGS AND CONCLUSIONS 39
VI DISCUSSION 43
APPENDIX: DESCRIPTION OF PEDIGREE CHARTS 45
BIBLIOGRAPHY 55
PEDIGREE CHARTS 56
iii |
any_adam_object | 1 |
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author | Davenport, Charles Benedict 1866-1944 |
author_GND | (DE-588)117622737 |
author_facet | Davenport, Charles Benedict 1866-1944 |
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author_sort | Davenport, Charles Benedict 1866-1944 |
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building | Verbundindex |
bvnumber | BV035176899 |
callnumber-first | Q - Science |
callnumber-label | QH431 |
callnumber-raw | QH431 |
callnumber-search | QH431 |
callnumber-sort | QH 3431 |
callnumber-subject | QH - Natural History and Biology |
ctrlnum | (OCoLC)2356974 (DE-599)BVBBV035176899 |
dewey-full | 575.123 616.44 |
dewey-hundreds | 500 - Natural sciences and mathematics 600 - Technology (Applied sciences) |
dewey-ones | 575 - Specific parts of & systems in plants 616 - Diseases |
dewey-raw | 575.123 616.44 |
dewey-search | 575.123 616.44 |
dewey-sort | 3575.123 |
dewey-tens | 570 - Biology 610 - Medicine and health |
discipline | Biologie Medizin |
discipline_str_mv | Biologie Medizin |
format | Book |
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institution | BVB |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016983735 |
oclc_num | 2356974 |
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physical | IV, 56 S. Ill. |
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publishDate | 1932 |
publishDateSearch | 1932 |
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publisher | Carnegie Inst. |
record_format | marc |
series | Papers of the Department of Genetics Publication |
series2 | Papers of the Department of Genetics Publication |
spelling | Davenport, Charles Benedict 1866-1944 Verfasser (DE-588)117622737 aut The genetical Factor in endemic goiter Charles B. Davenport Washington Carnegie Inst. 1932 IV, 56 S. Ill. txt rdacontent n rdamedia nc rdacarrier Papers of the Department of Genetics 37 Publication 428 Endemic goiter Genetic aspects Genetics, Medical Goiter, Endemic genetics Medical genetics Papers of the Department of Genetics 37 (DE-604)BV036888114 37 Publication 428 (DE-604)BV035415500 428 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016983735&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Davenport, Charles Benedict 1866-1944 The genetical Factor in endemic goiter Papers of the Department of Genetics Publication Endemic goiter Genetic aspects Genetics, Medical Goiter, Endemic genetics Medical genetics |
title | The genetical Factor in endemic goiter |
title_auth | The genetical Factor in endemic goiter |
title_exact_search | The genetical Factor in endemic goiter |
title_exact_search_txtP | The genetical Factor in endemic goiter |
title_full | The genetical Factor in endemic goiter Charles B. Davenport |
title_fullStr | The genetical Factor in endemic goiter Charles B. Davenport |
title_full_unstemmed | The genetical Factor in endemic goiter Charles B. Davenport |
title_short | The genetical Factor in endemic goiter |
title_sort | the genetical factor in endemic goiter |
topic | Endemic goiter Genetic aspects Genetics, Medical Goiter, Endemic genetics Medical genetics |
topic_facet | Endemic goiter Genetic aspects Genetics, Medical Goiter, Endemic genetics Medical genetics |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016983735&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV036888114 (DE-604)BV035415500 |
work_keys_str_mv | AT davenportcharlesbenedict thegeneticalfactorinendemicgoiter |