Structure, function, and modulation of neuronal voltage-gated ion channels:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley
2009
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 475 S., [6] Bl. Ill., graph. Darst. |
| ISBN: | 9780471930136 |
Internformat
MARC
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| 245 | 1 | 0 | |a Structure, function, and modulation of neuronal voltage-gated ion channels |c ed. by Valentin K. Gribkoff ... |
| 264 | 1 | |a Hoboken, NJ |b Wiley |c 2009 | |
| 300 | |a XIV, 475 S., [6] Bl. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Drug Discovery | |
| 650 | 4 | |a Drug development | |
| 650 | 4 | |a Ion Channel Gating | |
| 650 | 4 | |a Ion Channels |x drug effects | |
| 650 | 4 | |a Ion channels | |
| 650 | 4 | |a Ion channels |x Effect of drugs on | |
| 650 | 4 | |a Molecular pharmacology | |
| 650 | 4 | |a Neurons |x physiology | |
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| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Gribkoff, Valentin K. |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016969728&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-016969728 | ||
Datensatz im Suchindex
| _version_ | 1804138326898245632 |
|---|---|
| adam_text | CONTENTS
Preface
ix
Contributors
xi
PART I
NEURONAL
VOLTAGE-GATED ION
CHANNEL FUNCTIONS
1
1 Neuronal
L
-Туре
Voltage-Gated Calcium Channels
3
Alexander Scriabine and David J. Triggle
2
Voltage-Gated N-Type and
Т
-Type
Calcium Channels
and Excitability Disorders
35
Elizabeth Tringham and
Terranee
P. Snutch
3
Voltage-Gated Sodium Channels: Multiple Roles
in the Pathophysiology of Pain
67
Sulayman D. Dib-Hajj, Bryan C.
Hains,
Joel A. Black, and Stephen G. Waxman
4
The Role of Ion Channels in the Etiology
and Development of Gliomas
105
Amy K. Weaver and
Harald
Sontheimer
5
Shaker Family Kvl Voltage-Gated Potassium Channels
in Mammalian Brain Neurons
127
Helene
Vacher
and James S. Trimmer
vi
CONTENTS
6
Unique Mitochondrial Ion Channels: Roles in Synaptic
Transmission and Programmed Cell Death
155
Elizabeth A. Jonas
7
Regulation of
Neuronal
Excitability by the Sodium-Activated
Potassium Channels Slick (SLO2.1) and Slack (SLO2.2)
193
Valentin K. Gribkoff and Leonard K. Kaczmarek
PART II
MODULATORY
MECHANISMS AND INFLUENCES
ON
NEURONAL
VOLTAGE-GATED ION CHANNEL
FUNCTION
217
8
Alternative Splicing of
Neuronal Cav2
Calcium Channels
219
Diane Lipscombe, Summer E. Allen, Annette
С
Gray,
Spiro
Marangoudakis,
and Jesica Raingo
9
Effect of Hypoxia/Ischemia on Voltage-Dependent Channels
251
Xiang Q. Gu, Hang Yao, and Gabriel G. Haddad
10
In Vivo Roles of Ion Channel Regulatory Protein Complexes
in
Neuronal
Physiology and Behavior
279
Smitha
Ready, Mohammad Shahidullah, and
Irwin
В.
Levitán
11
Regulation of
Neuronal
Ion Channels by G-Protein-Coupled
Receptors in Sympathetic Neurons
291
Mark S. Shapiro and Nikita Gamper
12
BK Channels: Regulation of Expression
and Physiological Impact
317
Pallob Kundu, Abderrahmane Alioua, Yogesh Kumar, Rang
Lu,
Jimmy W.
Ou,
Enrique Sanchez-Pastor,
Min Li,
Enrico
Stefani,
and
Ligia Toro
13
Structural Basis for Auxiliary KChIP Modulation
of KV4 Channels
343
KeWei Wang and
Jijie Chai
PART III DRUG DISCOVERY TARGETS
AND TECHNOLOGY
363
14
Sodium Channel
Blockers
for the Treatment of Chronic Pain
365
Mark R. Bowlby and Edward Kaftan
15 Neuronal KV7
Potassium Channels as Emerging Targets
for the Treatment of Pain
393
Steven I. Dworetzky and Valentin K. Gribkoff
CONTENTS
vii
16
Small-Molecule Modulators of Large-Conductance,
Calcium-Activated (BK) Channels
423
John E.
Starrett
Jr.
17
High-Throughput Screening Technologies in Ion Channel
Drug Discovery
443
Edward B. Stevens, Andrew D. Whyment, and J. Mark Treherne
Index
467
|
| adam_txt |
CONTENTS
Preface
ix
Contributors
xi
PART I
NEURONAL
VOLTAGE-GATED ION
CHANNEL FUNCTIONS
1
1 Neuronal
L
-Туре
Voltage-Gated Calcium Channels
3
Alexander Scriabine and David J. Triggle
2
Voltage-Gated N-Type and
Т
-Type
Calcium Channels
and Excitability Disorders
35
Elizabeth Tringham and
Terranee
P. Snutch
3
Voltage-Gated Sodium Channels: Multiple Roles
in the Pathophysiology of Pain
67
Sulayman D. Dib-Hajj, Bryan C.
Hains,
Joel A. Black, and Stephen G. Waxman
4
The Role of Ion Channels in the Etiology
and Development of Gliomas
105
Amy K. Weaver and
Harald
Sontheimer
5
Shaker Family Kvl Voltage-Gated Potassium Channels
in Mammalian Brain Neurons
127
Helene
Vacher
and James S. Trimmer
vi
CONTENTS
6
Unique Mitochondrial Ion Channels: Roles in Synaptic
Transmission and Programmed Cell Death
155
Elizabeth A. Jonas
7
Regulation of
Neuronal
Excitability by the Sodium-Activated
Potassium Channels Slick (SLO2.1) and Slack (SLO2.2)
193
Valentin K. Gribkoff and Leonard K. Kaczmarek
PART II
MODULATORY
MECHANISMS AND INFLUENCES
ON
NEURONAL
VOLTAGE-GATED ION CHANNEL
FUNCTION
217
8
Alternative Splicing of
Neuronal Cav2
Calcium Channels
219
Diane Lipscombe, Summer E. Allen, Annette
С
Gray,
Spiro
Marangoudakis,
and Jesica Raingo
9
Effect of Hypoxia/Ischemia on Voltage-Dependent Channels
251
Xiang Q. Gu, Hang Yao, and Gabriel G. Haddad
10
In Vivo Roles of Ion Channel Regulatory Protein Complexes
in
Neuronal
Physiology and Behavior
279
Smitha
Ready, Mohammad Shahidullah, and
Irwin
В.
Levitán
11
Regulation of
Neuronal
Ion Channels by G-Protein-Coupled
Receptors in Sympathetic Neurons
291
Mark S. Shapiro and Nikita Gamper
12
BK Channels: Regulation of Expression
and Physiological Impact
317
Pallob Kundu, Abderrahmane Alioua, Yogesh Kumar, Rang
Lu,
Jimmy W.
Ou,
Enrique Sanchez-Pastor,
Min Li,
Enrico
Stefani,
and
Ligia Toro
13
Structural Basis for Auxiliary KChIP Modulation
of KV4 Channels
343
KeWei Wang and
Jijie Chai
PART III DRUG DISCOVERY TARGETS
AND TECHNOLOGY
363
14
Sodium Channel
Blockers
for the Treatment of Chronic Pain
365
Mark R. Bowlby and Edward Kaftan
15 Neuronal KV7
Potassium Channels as Emerging Targets
for the Treatment of Pain
393
Steven I. Dworetzky and Valentin K. Gribkoff
CONTENTS
vii
16
Small-Molecule Modulators of Large-Conductance,
Calcium-Activated (BK) Channels
423
John E.
Starrett
Jr.
17
High-Throughput Screening Technologies in Ion Channel
Drug Discovery
443
Edward B. Stevens, Andrew D. Whyment, and J. Mark Treherne
Index
467 |
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| spelling | Structure, function, and modulation of neuronal voltage-gated ion channels ed. by Valentin K. Gribkoff ... Hoboken, NJ Wiley 2009 XIV, 475 S., [6] Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Drug Discovery Drug development Ion Channel Gating Ion Channels drug effects Ion channels Ion channels Effect of drugs on Molecular pharmacology Neurons physiology Nervenzelle (DE-588)4041649-5 gnd rswk-swf Spannungskontrollierter Ionenkanal (DE-588)4717815-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nervenzelle (DE-588)4041649-5 s Spannungskontrollierter Ionenkanal (DE-588)4717815-2 s DE-604 Gribkoff, Valentin K. Sonstige oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016969728&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Structure, function, and modulation of neuronal voltage-gated ion channels Drug Discovery Drug development Ion Channel Gating Ion Channels drug effects Ion channels Ion channels Effect of drugs on Molecular pharmacology Neurons physiology Nervenzelle (DE-588)4041649-5 gnd Spannungskontrollierter Ionenkanal (DE-588)4717815-2 gnd |
| subject_GND | (DE-588)4041649-5 (DE-588)4717815-2 (DE-588)4143413-4 |
| title | Structure, function, and modulation of neuronal voltage-gated ion channels |
| title_auth | Structure, function, and modulation of neuronal voltage-gated ion channels |
| title_exact_search | Structure, function, and modulation of neuronal voltage-gated ion channels |
| title_exact_search_txtP | Structure, function, and modulation of neuronal voltage-gated ion channels |
| title_full | Structure, function, and modulation of neuronal voltage-gated ion channels ed. by Valentin K. Gribkoff ... |
| title_fullStr | Structure, function, and modulation of neuronal voltage-gated ion channels ed. by Valentin K. Gribkoff ... |
| title_full_unstemmed | Structure, function, and modulation of neuronal voltage-gated ion channels ed. by Valentin K. Gribkoff ... |
| title_short | Structure, function, and modulation of neuronal voltage-gated ion channels |
| title_sort | structure function and modulation of neuronal voltage gated ion channels |
| topic | Drug Discovery Drug development Ion Channel Gating Ion Channels drug effects Ion channels Ion channels Effect of drugs on Molecular pharmacology Neurons physiology Nervenzelle (DE-588)4041649-5 gnd Spannungskontrollierter Ionenkanal (DE-588)4717815-2 gnd |
| topic_facet | Drug Discovery Drug development Ion Channel Gating Ion Channels drug effects Ion channels Ion channels Effect of drugs on Molecular pharmacology Neurons physiology Nervenzelle Spannungskontrollierter Ionenkanal Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016969728&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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