Anemia in inflammatory bowel diseases:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Bremen [u.a.]
UNI-MED-Verl.
2008
|
| Ausgabe: | 1. Aufl. |
| Schriftenreihe: | UNI-MED science
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | 95 S. Ill., graph. Darst. |
| ISBN: | 9783837410495 3837410498 9781848151246 |
Internformat
MARC
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| 020 | |a 3837410498 |9 3-8374-1049-8 | ||
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| 245 | 1 | 0 | |a Anemia in inflammatory bowel diseases |c [Christoph Gasche. In collab. with Yves Beguin ...] |
| 250 | |a 1. Aufl. | ||
| 264 | 1 | |a Bremen [u.a.] |b UNI-MED-Verl. |c 2008 | |
| 300 | |a 95 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a UNI-MED science | |
| 650 | 4 | |a Anemia | |
| 650 | 4 | |a Anemia |x etiology | |
| 650 | 4 | |a Anemia |x physiopathology | |
| 650 | 4 | |a Anemia |x therapy | |
| 650 | 4 | |a Inflammatory Bowel Diseases |x complications | |
| 650 | 4 | |a Inflammatory bowel diseases | |
| 650 | 4 | |a Iron |x therapeutic use | |
| 650 | 0 | 7 | |a Anämie |0 (DE-588)4126536-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Chronische Darmentzündung |0 (DE-588)4273697-3 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Chronische Darmentzündung |0 (DE-588)4273697-3 |D s |
| 689 | 0 | 1 | |a Anämie |0 (DE-588)4126536-1 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Gasche, Christoph |e Sonstige |4 oth | |
| 700 | 1 | |a Beguin, Yves |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016716842&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
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Datensatz im Suchindex
| _version_ | 1804137986240020480 |
|---|---|
| adam_text | Contents 11
Contents
^| IBD and Anemia 16
1.1. Prevalence 16
1.1.1. Historic notes 16
1.1.2. Epidemiology of IBD 16
1.1.3. Epidemiology of Anemia 17
1.1.4. References 19
1.2. Clinical aspects 19
1.2.1. Inflammatory bowel diseases 19
1.2.2. Ulcerative colitis 20
1.2.3. Crohn s disease 21
1.2.4. Extraintestinal manifestations 21
1.2.4.1. Anemia 24
1.2.5. References 24
1.3. Differential diagnosis 25
1.3.1. Microcytic anemia 27
1.3.2. Normocytic anemia 30
1.3.3. Macrocytic anemia 32
1.3.4. References 35
^| Pathophysiology 38
2.1. Erythropoiesis 38
2.1.1. Erythropoiesis 38
2.1.2. Erythropoietin 40
2.1.3. References 42
2.2. Iron deficiency 42
2.2.1. Physiology of iron metabolism 42
2.2.2. Iron distribution and utilization 43
2.2.3. Regulation of iron homeostasis 44
2.2.3.1. Regulation by hepcidin 44
2.2.3.2. Regulation of the expression of iron related genes 45
2.2.4. Pathophysiology of iron deficiency 46
2.2.5. References 47
2.3. Anemia of chronic disease 47
2.3.1. Pathophysiology 47
2.3.2. Diagnosis 48
2.3.3. Treatment 50
2.3.4. References 51
2.4. Nutritional facts 51
2.4.1. Iron requirements 51
2.4.2. Iron absorption and regulation 51
2.43. References 53
12 Contents
m Therapy 56
3.1. Oral iron 56
3.1.1. Diagnosis and indications for treatment 56
3.1.2. Treatment goals 56
3.1.3. Which oral iron preparation, what dose and for how long? 56
3.1.4. Dietary and drug interactions 57
3.1.5. Other management considerations 58
3.1.6. Adverse effects 58
3.1.7. References 58
3.2. Intravenous iron in inflammatory bowel disease 59
3.2.1. Iron deficiency: The main cause of anemia in IBD 59
3.2.2. Pathophysiology 59
3.2.3. Limitations of oral iron therapy in IBD-related anemia 59
3.2.4. Modalities of intravenous iron therapy 60
3.2.5. Iron sucrose in IBD 61
3.2.6. Combined infliximab and IV iron therapy 61
3.2.7. Safety of iron sucrose 61
3.2.8. Towards an optimization of intravenous iron therapy 63
3.2.9. References 64
3.3. Erythropoietin 65
3.3.1. Erythropoiesis - Erythropoietin 65
3.3.2. Erythropoietic Agents 65
3.3.3. Erythropoietin in IBD 68
3.3.4. Mechanisms of action 68
3.3.5. Predictive factors of response 68
3.3.6. Safety issues 68
3.3.7. Conclusions 69
3.3.8. References 69
|^| Controversies 72
4.1. Iron, inflammation and oxidative stress 72
4.1.1. Iron: an essential but potentially harmful nutrient 72
4.1.2. Reactive oxygen species and oxidative stress 72
4.1.3. Oxidative damage 72
4.1.4. Antioxidant defences 73
4.1.5. Oxidative stress in inflammatory bowel disease 73
4.1.6. Iron in inflammatory bowel disease 73
4.1.7. References 74
4.2. Lessons learned from rodent models 74
4.2.1. Introduction 74
4.2.2. Iron and inflammatory activity 75
4.2.3. Rodent models 75
4.2.4. Iron supplementation and severity of colitis 75
4.2.5. Iron supplementation and colitis-associated carcinogenesis 78
4.2.6. Conclusion 79
4.2.7. References 79
Contents 13
4.3. Impact on quality of life 80
4.3.1. Health-related quality of life in IBD and the impact of anemia 80
4.3.2. Major dimensions of the health concept 80
4.3.3. Determinants of HRQOL 81
4.3.4. HRQOL in IBD 81
4.3.5. Impact of anemia on HRQOL in IBD 82
4.3.6. References 82
4.4. Guidance for clinical practice 83
4.4.1. Assessment 83
4.4.2. Treatment optimization 84
4.4.2.1. Treatment goals 84
4.4.2.2. Treatment algorithm 84
4.4.3. References 86
^| Key References and Useful Websites 90
B lndex 94
|
| adam_txt |
Contents 11
Contents
^| IBD and Anemia 16
1.1. Prevalence 16
1.1.1. Historic notes 16
1.1.2. Epidemiology of IBD 16
1.1.3. Epidemiology of Anemia 17
1.1.4. References 19
1.2. Clinical aspects 19
1.2.1. Inflammatory bowel diseases 19
1.2.2. Ulcerative colitis 20
1.2.3. Crohn's disease 21
1.2.4. Extraintestinal manifestations 21
1.2.4.1. Anemia 24
1.2.5. References 24
1.3. Differential diagnosis 25
1.3.1. Microcytic anemia 27
1.3.2. Normocytic anemia 30
1.3.3. Macrocytic anemia 32
1.3.4. References 35
^| Pathophysiology 38
2.1. Erythropoiesis 38
2.1.1. Erythropoiesis 38
2.1.2. Erythropoietin 40
2.1.3. References 42
2.2. Iron deficiency 42
2.2.1. Physiology of iron metabolism 42
2.2.2. Iron distribution and utilization 43
2.2.3. Regulation of iron homeostasis 44
2.2.3.1. Regulation by hepcidin 44
2.2.3.2. Regulation of the expression of iron related genes 45
2.2.4. Pathophysiology of iron deficiency 46
2.2.5. References 47
2.3. Anemia of chronic disease 47
2.3.1. Pathophysiology 47
2.3.2. Diagnosis 48
2.3.3. Treatment 50
2.3.4. References 51
2.4. Nutritional facts 51
2.4.1. Iron requirements 51
2.4.2. Iron absorption and regulation 51
2.43. References 53
12 Contents
m Therapy 56
3.1. Oral iron 56
3.1.1. Diagnosis and indications for treatment 56
3.1.2. Treatment goals 56
3.1.3. Which oral iron preparation, what dose and for how long? 56
3.1.4. Dietary and drug interactions 57
3.1.5. Other management considerations 58
3.1.6. Adverse effects 58
3.1.7. References 58
3.2. Intravenous iron in inflammatory bowel disease 59
3.2.1. Iron deficiency: The main cause of anemia in IBD 59
3.2.2. Pathophysiology 59
3.2.3. Limitations of oral iron therapy in IBD-related anemia 59
3.2.4. Modalities of intravenous iron therapy 60
3.2.5. Iron sucrose in IBD 61
3.2.6. Combined infliximab and IV iron therapy 61
3.2.7. Safety of iron sucrose 61
3.2.8. Towards an optimization of intravenous iron therapy 63
3.2.9. References 64
3.3. Erythropoietin 65
3.3.1. Erythropoiesis - Erythropoietin 65
3.3.2. Erythropoietic Agents 65
3.3.3. Erythropoietin in IBD 68
3.3.4. Mechanisms of action 68
3.3.5. Predictive factors of response 68
3.3.6. Safety issues 68
3.3.7. Conclusions 69
3.3.8. References 69
|^| Controversies 72
4.1. Iron, inflammation and oxidative stress 72
4.1.1. Iron: an essential but potentially harmful nutrient 72
4.1.2. Reactive oxygen species and oxidative stress 72
4.1.3. Oxidative damage 72
4.1.4. Antioxidant defences 73
4.1.5. Oxidative stress in inflammatory bowel disease 73
4.1.6. Iron in inflammatory bowel disease 73
4.1.7. References 74
4.2. Lessons learned from rodent models 74
4.2.1. Introduction 74
4.2.2. Iron and inflammatory activity 75
4.2.3. Rodent models 75
4.2.4. Iron supplementation and severity of colitis 75
4.2.5. Iron supplementation and colitis-associated carcinogenesis 78
4.2.6. Conclusion 79
4.2.7. References 79
Contents 13
4.3. Impact on quality of life 80
4.3.1. Health-related quality of life in IBD and the impact of anemia 80
4.3.2. Major dimensions of the health concept 80
4.3.3. Determinants of HRQOL 81
4.3.4. HRQOL in IBD 81
4.3.5. Impact of anemia on HRQOL in IBD 82
4.3.6. References 82
4.4. Guidance for clinical practice 83
4.4.1. Assessment 83
4.4.2. Treatment optimization 84
4.4.2.1. Treatment goals 84
4.4.2.2. Treatment algorithm 84
4.4.3. References 86
^| Key References and Useful Websites 90
B lndex 94 |
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| id | DE-604.BV035048118 |
| illustrated | Illustrated |
| index_date | 2024-07-02T21:55:32Z |
| indexdate | 2024-07-09T21:21:00Z |
| institution | BVB |
| isbn | 9783837410495 3837410498 9781848151246 |
| language | English |
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| physical | 95 S. Ill., graph. Darst. |
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| spelling | Anemia in inflammatory bowel diseases [Christoph Gasche. In collab. with Yves Beguin ...] 1. Aufl. Bremen [u.a.] UNI-MED-Verl. 2008 95 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier UNI-MED science Anemia Anemia etiology Anemia physiopathology Anemia therapy Inflammatory Bowel Diseases complications Inflammatory bowel diseases Iron therapeutic use Anämie (DE-588)4126536-1 gnd rswk-swf Chronische Darmentzündung (DE-588)4273697-3 gnd rswk-swf Chronische Darmentzündung (DE-588)4273697-3 s Anämie (DE-588)4126536-1 s DE-604 Gasche, Christoph Sonstige oth Beguin, Yves Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016716842&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Anemia in inflammatory bowel diseases Anemia Anemia etiology Anemia physiopathology Anemia therapy Inflammatory Bowel Diseases complications Inflammatory bowel diseases Iron therapeutic use Anämie (DE-588)4126536-1 gnd Chronische Darmentzündung (DE-588)4273697-3 gnd |
| subject_GND | (DE-588)4126536-1 (DE-588)4273697-3 |
| title | Anemia in inflammatory bowel diseases |
| title_auth | Anemia in inflammatory bowel diseases |
| title_exact_search | Anemia in inflammatory bowel diseases |
| title_exact_search_txtP | Anemia in inflammatory bowel diseases |
| title_full | Anemia in inflammatory bowel diseases [Christoph Gasche. In collab. with Yves Beguin ...] |
| title_fullStr | Anemia in inflammatory bowel diseases [Christoph Gasche. In collab. with Yves Beguin ...] |
| title_full_unstemmed | Anemia in inflammatory bowel diseases [Christoph Gasche. In collab. with Yves Beguin ...] |
| title_short | Anemia in inflammatory bowel diseases |
| title_sort | anemia in inflammatory bowel diseases |
| topic | Anemia Anemia etiology Anemia physiopathology Anemia therapy Inflammatory Bowel Diseases complications Inflammatory bowel diseases Iron therapeutic use Anämie (DE-588)4126536-1 gnd Chronische Darmentzündung (DE-588)4273697-3 gnd |
| topic_facet | Anemia Anemia etiology Anemia physiopathology Anemia therapy Inflammatory Bowel Diseases complications Inflammatory bowel diseases Iron therapeutic use Anämie Chronische Darmentzündung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016716842&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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