Essential concepts in toxicogenomics:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2008
|
| Schriftenreihe: | Methods in molecular biology
460 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XI, 277 S. Ill., graph. Darst. 25 cm |
| ISBN: | 9781588296382 1588296385 9781603270489 1603270485 |
Internformat
MARC
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| 245 | 1 | 0 | |a Essential concepts in toxicogenomics |c ed. by Donna L. Mendrick ... |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2008 | |
| 300 | |a XI, 277 S. |b Ill., graph. Darst. |c 25 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Methods in molecular biology |v 460 | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Genetic toxicology | |
| 650 | 4 | |a Genomics | |
| 650 | 4 | |a Toxicogenetics | |
| 650 | 4 | |a Génomique | |
| 650 | 4 | |a Toxicologie génétique | |
| 650 | 4 | |a Genetic toxicology | |
| 650 | 4 | |a Genomics | |
| 650 | 4 | |a Toxicogenetics | |
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| 689 | 0 | |C b |5 DE-604 | |
| 700 | 1 | |a Mendrick, Donna L. |e Sonstige |4 oth | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-016699656 | ||
Datensatz im Suchindex
| _version_ | 1804137960935784448 |
|---|---|
| adam_text | Contents
Preface
.................................................................
v
Contributors
............................................................ ix
Color Plates
............................................................ xi
1
Toxicogenomics and Classic Toxicology: How to Improve
Prediction and Mechanistic Understanding of Human
Toxicity
Donna
L Mendrick
............................................... 1
2
Use of Traditional End Points and Gene Dysregulation
to Understand Mechanisms of
Toxicity:
Toxicogenomics
in Mechanistic Toxicology
Wayne R. Buck, Jeffrey F. Waring, and Eric A. Blomme
............ 23
3
Quality Control of Microarray Assays for Toxicogenomic
and In Vitro Diagnostic Applications
Karol L
Thompson and Joseph Hackett
............................ 45
4
Role of Statistics in Toxicogenomics
Michael Elashoff
.................................................. 69
5
Predictive Toxicogenomics in Preclinical Discovery
Scott A.
Barros
and Rory B. Martin
................................ 89
6
In Vivo Predictive Toxicogenomics
Mark W. Porter
...................................................113
7
Bioinformatics: Databasing and Gene Annotation
Lyle D. Burgoon and Timothy R. Zacharewski
.....................145
8
Microarray Probe Mapping and Annotation in Cross-Species
Comparative Toxicogenomics
John
N.
Calley, William B. Mattes, and Timothy P. Ryan
...........159
9
Toxicogenomics in
Biomarker
Discovery
Marc F. DeCristofaro and Kellye K. Daniels
........................185
10
From Pharmacogenomics to Translational
Biomarkers
Donna
L
Mendrick
............................................... 195
11
Public Consortium Efforts in Toxicogenomics
William B. Mattes
.................................................221
VII
viii Contents
12
Applications
of Toxicogenomics to Nonclinical Drug
Development: Regulatory Science Considerations
Frank D.
Sistare
and Joseph J.
DeGeorge
..........................239
Index
...................................................................263
|
| adam_txt |
Contents
Preface
.
v
Contributors
. ix
Color Plates
. xi
1
Toxicogenomics and Classic Toxicology: How to Improve
Prediction and Mechanistic Understanding of Human
Toxicity
Donna
L Mendrick
. 1
2
Use of Traditional End Points and Gene Dysregulation
to Understand Mechanisms of
Toxicity:
Toxicogenomics
in Mechanistic Toxicology
Wayne R. Buck, Jeffrey F. Waring, and Eric A. Blomme
. 23
3
Quality Control of Microarray Assays for Toxicogenomic
and In Vitro Diagnostic Applications
Karol L
Thompson and Joseph Hackett
. 45
4
Role of Statistics in Toxicogenomics
Michael Elashoff
. 69
5
Predictive Toxicogenomics in Preclinical Discovery
Scott A.
Barros
and Rory B. Martin
. 89
6
In Vivo Predictive Toxicogenomics
Mark W. Porter
.113
7
Bioinformatics: Databasing and Gene Annotation
Lyle D. Burgoon and Timothy R. Zacharewski
.145
8
Microarray Probe Mapping and Annotation in Cross-Species
Comparative Toxicogenomics
John
N.
Calley, William B. Mattes, and Timothy P. Ryan
.159
9
Toxicogenomics in
Biomarker
Discovery
Marc F. DeCristofaro and Kellye K. Daniels
.185
10
From Pharmacogenomics to Translational
Biomarkers
Donna
L
Mendrick
. 195
11
Public Consortium Efforts in Toxicogenomics
William B. Mattes
.221
VII
viii Contents
12
Applications
of Toxicogenomics to Nonclinical Drug
Development: Regulatory Science Considerations
Frank D.
Sistare
and Joseph J.
DeGeorge
.239
Index
.263 |
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| spelling | Essential concepts in toxicogenomics ed. by Donna L. Mendrick ... Totowa, NJ Humana Press 2008 XI, 277 S. Ill., graph. Darst. 25 cm txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 460 Includes bibliographical references and index Genetic toxicology Genomics Toxicogenetics Génomique Toxicologie génétique Gentoxikologie (DE-588)4338045-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Gentoxikologie (DE-588)4338045-1 s b DE-604 Mendrick, Donna L. Sonstige oth Methods in molecular biology 460 (DE-604)BV035362695 460 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016699656&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| subject_GND | (DE-588)4338045-1 (DE-588)4143413-4 |
| title | Essential concepts in toxicogenomics |
| title_auth | Essential concepts in toxicogenomics |
| title_exact_search | Essential concepts in toxicogenomics |
| title_exact_search_txtP | Essential concepts in toxicogenomics |
| title_full | Essential concepts in toxicogenomics ed. by Donna L. Mendrick ... |
| title_fullStr | Essential concepts in toxicogenomics ed. by Donna L. Mendrick ... |
| title_full_unstemmed | Essential concepts in toxicogenomics ed. by Donna L. Mendrick ... |
| title_short | Essential concepts in toxicogenomics |
| title_sort | essential concepts in toxicogenomics |
| topic | Genetic toxicology Genomics Toxicogenetics Génomique Toxicologie génétique Gentoxikologie (DE-588)4338045-1 gnd |
| topic_facet | Genetic toxicology Genomics Toxicogenetics Génomique Toxicologie génétique Gentoxikologie Aufsatzsammlung |
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