Clinical management of bone and joint pain:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York
Haworth Medical Press
2007
|
| Schriftenreihe: | Haworth series in clinical pain and symptom palliation
|
| Schlagworte: | |
| Online-Zugang: | Table of contents only Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XVI, 418 S. Ill. 22 cm |
| ISBN: | 9780789031457 0789031450 9780789031464 0789031469 |
Internformat
MARC
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| 245 | 1 | 0 | |a Clinical management of bone and joint pain |c Gary McCleane, Howard S. Smith, ed. |
| 264 | 1 | |a New York |b Haworth Medical Press |c 2007 | |
| 300 | |a XVI, 418 S. |b Ill. |c 22 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Haworth series in clinical pain and symptom palliation | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Pain |x Treatment | |
| 650 | 4 | |a Bones |x Diseases |x Treatment | |
| 650 | 4 | |a Joints |x Diseases |x Treatment | |
| 650 | 4 | |a Bone and Bones |x physiology | |
| 650 | 4 | |a Pain |x drug therapy | |
| 650 | 4 | |a Analgesics |x therapeutic use | |
| 650 | 4 | |a Joints |x physiology | |
| 700 | 1 | |a McCleane, Gary J. |e Sonstige |0 (DE-588)135843383 |4 oth | |
| 700 | 1 | |a Smith, Howard S. |d 1956- |e Sonstige |0 (DE-588)135568706 |4 oth | |
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Datensatz im Suchindex
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|---|---|
| adam_text | CONTENTS
About the Editors xiii
Contributors xv
Introduction 1
Gary McCleane
PARTI
Chapter 1. Basic Pain Mechanisms 7
Jana Sawynok
Introduction 7
Joint Innervation and Activation 8
Models of Inflammation 9
Pain in Arthritis 10
Conclusion 20
Chapter 2. The Physiology and Basic Science
of Bone and Joints 25
Helen Cohen
David Blake
Skeletal Developmental Biology 25
Molecular Genetics 29
Mature Joint Tissues 29
Mature Bone 30
Gross Structure 31
Microscopic Structure 33
Mature Cartilage 33
Synovium 36
Synovial Fluid 39
Tendons 41
Ligaments 41
Bursae 41
Circulation 42
Joint Stability 42
Synovium and Inflammation 44
Summary 46
PART II
Chapter 3. NSAIDs for Painful Bone
and Joint Conditions 51
Jennifer A. Elliott
Howard S. Smith
Introduction 51
Mechanisms of Action of NSAIDs 52
Gastrointestinal Effects of NSAIDs 54
Renal Effects of NSAIDs 54
Platelet Effects of NSAIDs 55
Central Nervous System Effects of NSAIDs 56
Other NSAID Effects 56
Classification of NSAIDs 57
Potential Adverse Drug Interactions with NSAIDs 61
Conclusion 63
Chapter 4. Capsaicin 65
Gary McCleane
Clinical Use of Capsaicin 66
Side Effects of Topical Capsaicin Application 67
Unanswered Questions Regarding Use of Capsaicin 69
Suggested Clinical Use of Capsaicin 70
Strategies to Reduce Discomfort of Application
of Capsaicin 70
Chapter 5. Topical Nitrates 73
Gary McCleane
Mode of Action of Topical Nitrates When Used
As Analgesics 74
Human Experimental Pain 74
Studies Suggesting an Analgesic Effect When Nitrates
Are Used Topically 74
Effect of Topical Glyceryl Trinitrate on Inflammation 76
Effect of Topical Nitrate on Analgesic Effect of Opioids 77
Issues with the Use of Transdermal Nitrates 78
Glyceryl Trinitrate Formulations 79
Side Effects of Topical Glyceryl Trinitrate 79
Suggested Clinical Use 80
Chapter 6. Topical Analgesic Options 83
Charles A rgoff
Topical versus Transdermal 83
Choice of Agents 88
Other Uses of Topical Analgesics 96
Chapter 7A. Intra-Articular Injections 103
William Lavelle
Elizabeth Demers
Lori Lavelle
History of Intra-Articular Steroid Injections 103
Mechanism of Action of Intra-Articular Steroid Injections 104
Selected Injection Techniques 115
Chapter 7B. Nerve Blocks 127
Elizabeth Demers
William Lavelle
Lori Lavelle
Introduction 127
Upper Extremity Blocks 127
Lower Extremity Nerve Blocks 135
Techniques for Localization of a Nerve 143
Chapter 8. Opioids 149
Gary McCleane
Pain and Its Responsiveness to Opioids 150
Effect of Peripheral Application of Opioids
for Acute Pain 151
Codeine 152
Dihydrocodeine 152
Tramadol 153
Meperidine 154
Propoxyphene 154
Pentazocine 154
Morphine 154
Diamorphine 156
Hydromorphone 156
Methadone 156
Fentanyl 157
B uprenorphine 159
Oxycodone 159
Side Effects of Opioid Analgesics 159
Conclusions 166
Chapter 9. Acetaminophen 175
Nisar Soomro
Structure 175
Mechanism of Action 176
Absorption 176
Metabolism 176
Toxicity 177
Antidote 177
Indications 178
Formulations 178
Dose 178
Arthritic Pain 178
Interactions 179
Conclusions 180
Chapter 10. Glucosamine 181
William Lavelle
Elizabeth Demers
Lori Lavelle
History 181
Mechanism of Action 182
Clinical Trials 183
Safety and Adverse Reactions 186
Discussion 186
Chapter 11. Clinical Pharmacology of Glucocorticoids 189
Muhammad A. Munir
Jim-Ming Zhang
Introduction 189
Corticosteroids 190
Pharmacodynamics 190
Pharmacokinetics 197
Clinical Pharmacology 198
Clinical Summary 206
Chapter 12. Hyaluronic Acid 209
William Lavelle
Elizabeth Demers
Lori Lavelle
History 209
Mechanism of Action 210
Clinical Trials 213
Safety and Adverse Reactions 214
Discussion 215
Chapter 13. Disease-Modifying Antirheumatic Drugs 221
Lori Lavelle
William Lavelle
Elizabeth Demers
Introduction 221
Antimalarials 222
Glucocorticoids 223
Methotrexate 224
Leflunomide 225
Sulfasalazine . 226
Azathiprine 227
Cyclosporine 228
D-Penicillamine 229
Cyclophosphamide 230
Mycophenolate Mofetil 231
Gold 232
Biologic Agents 232
Chapter 14. Physical Therapy 243
Denis Martin
Introduction 243
Function 244
Addressing Impairment: A Biomedical Application
of Physical Therapy 245
Addressing Activity and Participation: A Biopsychosocial
Application of Physical Therapy 248
Conclusion 253
Chapter 15. Acupuncture 257
Gira Patel
Introduction 257
How Acupuncture Works 258
History and Philosophy 259
Treatment Principles 262
Conditions Treated 264
Chapter 16. Botulinum Toxin 269
Charles Argqff
Introduction 269
The Current USFDA-Approved Uses of the Botulinum
Toxins 271
The Use of the Botulinum Toxins for the Treatment
of Chronic Headache 272
The Use of Botulinum Toxin in the Management
of Musculoskeletal Pain 276
The Use of Botulinum Toxin in the Management
of Neuropathic Pain and Other Painful Conditions 280
Chapter 17. Radiopharmaceuticals 287
Rahul Parikh
Howard S. Smith
Introduction 287
Pathophysiology of Painful Osseous Metastases 289
Current Treatment Options 292
Radiopharmaceutical Agents—Overview 294
Radiopharmaceutical Agents 297
Investigational Radiopharmaceuticals 307
Patient Selection Criteria and Treatment Guidelines 311
Administration of Radiopharmaceuticals and Follow-Up 313
Future Work 315
Conclusion 317
Chapter 18. Muscle Relaxants 325
Gary McCleane
Baclofen 327
Benzodiazepines 327
Carisoprodol 328
Cyclobenzaprine 328
Dantrolene 329
Metaxalone 329
Methocarbamol 329
Orphenadrine 329
Tizanadine 330
Miscellaneous 330
Suggested Clinical Use of Muscle Relaxant Drugs 331
Chapter 19. Other Options 335
Howard S. Smith
Mark Guerdon
NSAIDs 335
Biosynthetic Options 340
The Future 353
Summary 355
PART III
Chapter 20. Joint Pain 361
Gary McCleane
Monoarticular Pain 362
Polyarticular Options 363
Chapter 21. Fracture Pain 365
Gary McCleane
Is Fracture Pain Adequately Treated? 366
Pharmacological Options 367
Treatment of Specific Fractures 372
Chapter 22. Pathophysiology and Analgesic Approaches
to Painful Bone Metastasis 381
Howard S. Smith
Jennifer A. Elliott
Introduction 381
Pathophysiology of Bone Resorption 384
Osteoclast Osteolysis 385
Modulation of Osteoclastic Activity
Modulates Nociception 386
Chapter 23. Pain Arising from Tendons
and Tendon Sheaths 393
Gary McCleane
Topical Options 394
Injections 396
Oral Options 399
Others 400
Suggested Treatment for Tendon-Related Pain 402
Chapter 24. When Is Pain Felt Over a Bone or Joint,
Not Bone or Joint Pain? 405
Gary McCleane
Radiated Pain/Neuropathic Pain 405
Referred Pain 407
Complex Regional Pain Syndrome 409
Aid to Diagnosis 412
Index 413
|
| adam_txt |
CONTENTS
About the Editors xiii
Contributors xv
Introduction 1
Gary McCleane
PARTI
Chapter 1. Basic Pain Mechanisms 7
Jana Sawynok
Introduction 7
Joint Innervation and Activation 8
Models of Inflammation 9
Pain in Arthritis 10
Conclusion 20
Chapter 2. The Physiology and Basic Science
of Bone and Joints 25
Helen Cohen
David Blake
Skeletal Developmental Biology 25
Molecular Genetics 29
Mature Joint Tissues 29
Mature Bone 30
Gross Structure 31
Microscopic Structure 33
Mature Cartilage 33
Synovium 36
Synovial Fluid 39
Tendons 41
Ligaments 41
Bursae 41
Circulation 42
Joint Stability 42
Synovium and Inflammation 44
Summary 46
PART II
Chapter 3. NSAIDs for Painful Bone
and Joint Conditions 51
Jennifer A. Elliott
Howard S. Smith
Introduction 51
Mechanisms of Action of NSAIDs 52
Gastrointestinal Effects of NSAIDs 54
Renal Effects of NSAIDs 54
Platelet Effects of NSAIDs 55
Central Nervous System Effects of NSAIDs 56
Other NSAID Effects 56
Classification of NSAIDs 57
Potential Adverse Drug Interactions with NSAIDs 61
Conclusion 63
Chapter 4. Capsaicin 65
Gary McCleane
Clinical Use of Capsaicin 66
Side Effects of Topical Capsaicin Application 67
Unanswered Questions Regarding Use of Capsaicin 69
Suggested Clinical Use of Capsaicin 70
Strategies to Reduce Discomfort of Application
of Capsaicin 70
Chapter 5. Topical Nitrates 73
Gary McCleane
Mode of Action of Topical Nitrates When Used
As Analgesics 74
Human Experimental Pain 74
Studies Suggesting an Analgesic Effect When Nitrates
Are Used Topically 74
Effect of Topical Glyceryl Trinitrate on Inflammation 76
Effect of Topical Nitrate on Analgesic Effect of Opioids 77
Issues with the Use of Transdermal Nitrates 78
Glyceryl Trinitrate Formulations 79
Side Effects of Topical Glyceryl Trinitrate 79
Suggested Clinical Use 80
Chapter 6. Topical Analgesic Options 83
Charles A rgoff
Topical versus Transdermal 83
Choice of Agents 88
Other Uses of Topical Analgesics 96
Chapter 7A. Intra-Articular Injections 103
William Lavelle
Elizabeth Demers
Lori Lavelle
History of Intra-Articular Steroid Injections 103
Mechanism of Action of Intra-Articular Steroid Injections 104
Selected Injection Techniques 115
Chapter 7B. Nerve Blocks 127
Elizabeth Demers
William Lavelle
Lori Lavelle
Introduction 127
Upper Extremity Blocks 127
Lower Extremity Nerve Blocks 135
Techniques for Localization of a Nerve 143
Chapter 8. Opioids 149
Gary McCleane
Pain and Its Responsiveness to Opioids 150
Effect of Peripheral Application of Opioids
for Acute Pain 151
Codeine 152
Dihydrocodeine 152
Tramadol 153
Meperidine 154
Propoxyphene 154
Pentazocine 154
Morphine 154
Diamorphine 156
Hydromorphone 156
Methadone 156
Fentanyl 157
B uprenorphine 159
Oxycodone 159
Side Effects of Opioid Analgesics 159
Conclusions 166
Chapter 9. Acetaminophen 175
Nisar Soomro
Structure 175
Mechanism of Action 176
Absorption 176
Metabolism 176
Toxicity 177
Antidote 177
Indications 178
Formulations 178
Dose 178
Arthritic Pain 178
Interactions 179
Conclusions 180
Chapter 10. Glucosamine 181
William Lavelle
Elizabeth Demers
Lori Lavelle
History 181
Mechanism of Action 182
Clinical Trials 183
Safety and Adverse Reactions 186
Discussion 186
Chapter 11. Clinical Pharmacology of Glucocorticoids 189
Muhammad A. Munir
Jim-Ming Zhang
Introduction 189
Corticosteroids 190
Pharmacodynamics 190
Pharmacokinetics 197
Clinical Pharmacology 198
Clinical Summary 206
Chapter 12. Hyaluronic Acid 209
William Lavelle
Elizabeth Demers
Lori Lavelle
History 209
Mechanism of Action 210
Clinical Trials 213
Safety and Adverse Reactions 214
Discussion 215
Chapter 13. Disease-Modifying Antirheumatic Drugs 221
Lori Lavelle
William Lavelle
Elizabeth Demers
Introduction 221
Antimalarials 222
Glucocorticoids 223
Methotrexate 224
Leflunomide 225
Sulfasalazine . 226
Azathiprine 227
Cyclosporine 228
D-Penicillamine 229
Cyclophosphamide 230
Mycophenolate Mofetil 231
Gold 232
Biologic Agents 232
Chapter 14. Physical Therapy 243
Denis Martin
Introduction 243
Function 244
Addressing Impairment: A Biomedical Application
of Physical Therapy 245
Addressing Activity and Participation: A Biopsychosocial
Application of Physical Therapy 248
Conclusion 253
Chapter 15. Acupuncture 257
Gira Patel
Introduction 257
How Acupuncture Works 258
History and Philosophy 259
Treatment Principles 262
Conditions Treated 264
Chapter 16. Botulinum Toxin 269
Charles Argqff
Introduction 269
The Current USFDA-Approved Uses of the Botulinum
Toxins 271
The Use of the Botulinum Toxins for the Treatment
of Chronic Headache 272
The Use of Botulinum Toxin in the Management
of Musculoskeletal Pain 276
The Use of Botulinum Toxin in the Management
of Neuropathic Pain and Other Painful Conditions 280
Chapter 17. Radiopharmaceuticals 287
Rahul Parikh
Howard S. Smith
Introduction 287
Pathophysiology of Painful Osseous Metastases 289
Current Treatment Options 292
Radiopharmaceutical Agents—Overview 294
Radiopharmaceutical Agents 297
Investigational Radiopharmaceuticals 307
Patient Selection Criteria and Treatment Guidelines 311
Administration of Radiopharmaceuticals and Follow-Up 313
Future Work 315
Conclusion 317
Chapter 18. Muscle Relaxants 325
Gary McCleane
Baclofen 327
Benzodiazepines 327
Carisoprodol 328
Cyclobenzaprine 328
Dantrolene 329
Metaxalone 329
Methocarbamol 329
Orphenadrine 329
Tizanadine 330
Miscellaneous 330
Suggested Clinical Use of Muscle Relaxant Drugs 331
Chapter 19. Other Options 335
Howard S. Smith
Mark Guerdon
NSAIDs 335
Biosynthetic Options 340
The Future 353
Summary 355
PART III
Chapter 20. Joint Pain 361
Gary McCleane
Monoarticular Pain 362
Polyarticular Options 363
Chapter 21. Fracture Pain 365
Gary McCleane
Is Fracture Pain Adequately Treated? 366
Pharmacological Options 367
Treatment of Specific Fractures 372
Chapter 22. Pathophysiology and Analgesic Approaches
to Painful Bone Metastasis 381
Howard S. Smith
Jennifer A. Elliott
Introduction 381
Pathophysiology of Bone Resorption 384
Osteoclast Osteolysis 385
Modulation of Osteoclastic Activity
Modulates Nociception 386
Chapter 23. Pain Arising from Tendons
and Tendon Sheaths 393
Gary McCleane
Topical Options 394
Injections 396
Oral Options 399
Others 400
Suggested Treatment for Tendon-Related Pain 402
Chapter 24. When Is Pain Felt Over a Bone or Joint,
Not Bone or Joint Pain? 405
Gary McCleane
Radiated Pain/Neuropathic Pain 405
Referred Pain 407
Complex Regional Pain Syndrome 409
Aid to Diagnosis 412
Index 413 |
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| id | DE-604.BV035023030 |
| illustrated | Illustrated |
| index_date | 2024-07-02T21:46:58Z |
| indexdate | 2024-07-09T21:20:26Z |
| institution | BVB |
| isbn | 9780789031457 0789031450 9780789031464 0789031469 |
| language | English |
| lccn | 2007000528 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016692120 |
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| physical | XVI, 418 S. Ill. 22 cm |
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| series2 | Haworth series in clinical pain and symptom palliation |
| spelling | Clinical management of bone and joint pain Gary McCleane, Howard S. Smith, ed. New York Haworth Medical Press 2007 XVI, 418 S. Ill. 22 cm txt rdacontent n rdamedia nc rdacarrier Haworth series in clinical pain and symptom palliation Includes bibliographical references and index Pain Treatment Bones Diseases Treatment Joints Diseases Treatment Bone and Bones physiology Pain drug therapy Analgesics therapeutic use Joints physiology McCleane, Gary J. Sonstige (DE-588)135843383 oth Smith, Howard S. 1956- Sonstige (DE-588)135568706 oth http://www.loc.gov/catdir/toc/ecip078/2007000528.html Table of contents only HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016692120&sequence=000008&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Clinical management of bone and joint pain Pain Treatment Bones Diseases Treatment Joints Diseases Treatment Bone and Bones physiology Pain drug therapy Analgesics therapeutic use Joints physiology |
| title | Clinical management of bone and joint pain |
| title_auth | Clinical management of bone and joint pain |
| title_exact_search | Clinical management of bone and joint pain |
| title_exact_search_txtP | Clinical management of bone and joint pain |
| title_full | Clinical management of bone and joint pain Gary McCleane, Howard S. Smith, ed. |
| title_fullStr | Clinical management of bone and joint pain Gary McCleane, Howard S. Smith, ed. |
| title_full_unstemmed | Clinical management of bone and joint pain Gary McCleane, Howard S. Smith, ed. |
| title_short | Clinical management of bone and joint pain |
| title_sort | clinical management of bone and joint pain |
| topic | Pain Treatment Bones Diseases Treatment Joints Diseases Treatment Bone and Bones physiology Pain drug therapy Analgesics therapeutic use Joints physiology |
| topic_facet | Pain Treatment Bones Diseases Treatment Joints Diseases Treatment Bone and Bones physiology Pain drug therapy Analgesics therapeutic use Joints physiology |
| url | http://www.loc.gov/catdir/toc/ecip078/2007000528.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016692120&sequence=000008&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT mccleanegaryj clinicalmanagementofboneandjointpain AT smithhowards clinicalmanagementofboneandjointpain |