Free radical effects on membranes:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, Acad. Press
2008
|
| Ausgabe: | 1. ed. |
| Schriftenreihe: | Current topics in membranes
61 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVIII, 262 S., [8] Bl. Ill., graph. Darst. |
| ISBN: | 9780123738790 |
Internformat
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| 245 | 1 | 0 | |a Free radical effects on membranes |c ed. by Sadis Matalon ... |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier, Acad. Press |c 2008 | |
| 300 | |a XVIII, 262 S., [8] Bl. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-016685810 | ||
Datensatz im Suchindex
| _version_ | 1804137940091142144 |
|---|---|
| adam_text | Contents
Contributors
ix
Previous Volumes in Series
xiii
I. Ooeroiew
CHAPTER
1
Structure and Functions of
Biomembranes
James F. Co/lawn and
Zsuzsa Bebök
I. Cell Membrane Structure and Function
1
II. Overview of Membrane Functions
4
III. Calcium Signaling
14
IV. Oxidative Stress and
Organelle
Dysfunction
15
References
19
CHAPTER
2
The Interaction of Reactive Oxygen and Nitrogen
Species with Membranes
Matías
N. Möller,
Jack
R.
Lancaster and Ana Denicola
I. Reactive Oxygen and Nitrogen Species
23
II. Physical Interactions: Compartmentalizing
Reactivity
25
III. Chemical Effects:
Lipid
Peroxidation
35
References
39
//.
Interaction of RONS with Channels and Pumps
CHAPTER
3
Modulation of Lung Epithelial Sodium Channel
Function by Nitric Oxide
Weifeng Song, Ahmed Lazrak, Shipeng Wei, Phillip McArdle and Sadis
Matalón
I. Introduction
44
References
62
v¡
Contents
CHAPTER
4
Effects of Nitrogen Oxides on Chloride Channels
Benjamin
Gaston
I. Overview
71
II. Introduction
72
III. Regulation by Nitrogen Oxides of Swelling-activated
СГ
Channels
73
IV. Regulation of Calcium Activated Cl~ Channels by
Nitrogen Oxides
(NÖJ
74
V. Effects of Nitrogen Oxides on CFTR
76
VI. Future Directions
82
References
83
CHAPTER
5
A Mitochondria-AOS-Kv Channel Axis in Health and
Disease; New Insights and Therapeutic Targets for
Vascular Disease and Cancer
Gopinuth Sutemlra and Evangelos D. Miehelakis
I. Introduction
87
II. The Components of the Mitochondria-ROS-Kv
Axis
88
III. The Mitochondria-AOS-Kv Axis in Hypoxia: HPV
92
IV. The Mitochondria-AOS-Kv Axis, Metabolism and
Apoptosis
97
References
108
CHAPTER
6
Oxidative Modification of Ca2+ Channels, Ryanodine
Receptors, and the Sarco/Endoplasmic Reticulum
Ca2+-ATPase
Victor S. Sluirov and Christian
Schöneich
I. Introduction
114
II. Overview of Ca-+
Translocation
Membrane
Proteins
114
III. Ca2+ Channels
115
IV.
SERCA
119
V. PMC A
124
VI. Concluding Remarks
125
References
125
CHAPTER
7
Regulation of Na.K-ATPase by Reactive Oxygen
Species
Giiofci Zhou. Laura
A. Dada
and Jacob I. Sznujder
I. Na.K-ATPase
132
II. Na.K-ATPase in Alveolar Fluid
Reabsorption
133
Contents
vii
III. Role of
Reactive
Oxygen Species in Signaling
134
IV. Regulation of Na.K-ATPase and Alveolar Fluid
Reabsorption
by
ROS
136
V. Dopamine and
ß-adrenergic
Agonists Improve
ROS-Mediated Decrease in Alveolar Fluid
Reabsorption
140
VI. Summary
141
References
141
///.
RONS and Membrane Permeability
CHAPTER
8
Reactive Oxygen Species and Endothelial
Permeability
Musako
Ushio-Fukai.
Ramialt
S. ľivx,
l olmi
ľukui
und A mr
II
Malik
I. Introduction
148
II.
Generation and Metabolism of
ROS
151
III. ROS
Generating System in ECs (NADPH
Oxidase)
151
IV. Regulation of Adherens Junctions
(
AJs) by
Phosphorylation and by Rho GTPase
153
V. ROS-generating Stimulants which Regulate Endothelial
Permeability
154
VI.
ROS
Reducing Factors/Proteins which Block
Endothelial Permeability
165
VII.
Molecular Targets of
ROS
Regulating Endothelial
Permeability
165
VIII.
Mediators/Regulators of ROS-dependent Endothelial
Permeability
171
IX. Functional Significance of ROS-dependent Endothelial
Permeability in Vivo
173
X. Summary and Conclusions
175
References
176
IV, RONS and Signal Transduction
CHAPTER
9
Cell Signaling by Oxidants: Pathways Leading to
Activation of Mitogen-activated Protein Kinases
(МАРК)
and Activator Protein-
1
(AP-I)
Ani
Sluikla and Brouke T. Mosumrn
I. Introduction
192
II.
МАРК
Signaling
195
VIH
Contents
III. Mitogen-activated
Protein Kinase Phosphatases
(MKPs)
198
IV. Relationships between
МАРК
and Activator Protein-
1
(AP-1)
199
V. Conclusions
203
References
204
CHAPTER
10
The Interaction of Mitochondrial Membranes with
Reactive Oxygen and Nitrogen Species
Paul S. Brookes, Andrew P. Wojtovich, Lindsay S. Burwell, David L. Hoffman
and Sergiy M. Nadtochiy
I. Mitochondria as a Source of Reactive Species
212
II. Effects of
ROS
and RNS on Mitochondrial
Respiration
217
III. Mitochondrial Membrane Lipids
221
IV.
ROS, RNS
&
Mitochondrial Ion Transport
224
V. Complex Interactions
&
Concluding Remarks
230
References
232
CHAPTER
11
Oxidant
Stress and Airway Epithelial Function
Jenora T. Waterman and Kenneth B.
Adler
I. Introduction
243
II. Sources of Reactive Oxygen Species
244
III. Antioxidant
Defenses in Airway Epithelium
245
IV. Oxidant-induced Airway Epithelial Responses
247
V. Conclusions
251
References
251
Index
257
|
| adam_txt |
Contents
Contributors
ix
Previous Volumes in Series
xiii
I. Ooeroiew
CHAPTER
1
Structure and Functions of
Biomembranes
James F. Co/lawn and
Zsuzsa Bebök
I. Cell Membrane Structure and Function
1
II. Overview of Membrane Functions
4
III. Calcium Signaling
14
IV. Oxidative Stress and
Organelle
Dysfunction
15
References
19
CHAPTER
2
The Interaction of Reactive Oxygen and Nitrogen
Species with Membranes
Matías
N. Möller,
Jack
R.
Lancaster and Ana Denicola
I. Reactive Oxygen and Nitrogen Species
23
II. Physical Interactions: Compartmentalizing
Reactivity
25
III. Chemical Effects:
Lipid
Peroxidation
35
References
39
//.
Interaction of RONS with Channels and Pumps
CHAPTER
3
Modulation of Lung Epithelial Sodium Channel
Function by Nitric Oxide
Weifeng Song, Ahmed Lazrak, Shipeng Wei, Phillip McArdle and Sadis
Matalón
I. Introduction
44
References
62
v¡
Contents
CHAPTER
4
Effects of Nitrogen Oxides on Chloride Channels
Benjamin
Gaston
I. Overview
71
II. Introduction
72
III. Regulation by Nitrogen Oxides of Swelling-activated
СГ
Channels
73
IV. Regulation of Calcium Activated Cl~ Channels by
Nitrogen Oxides
(NÖJ
74
V. Effects of Nitrogen Oxides on CFTR
76
VI. Future Directions
82
References
83
CHAPTER
5
A Mitochondria-AOS-Kv Channel Axis in Health and
Disease; New Insights and Therapeutic Targets for
Vascular Disease and Cancer
Gopinuth Sutemlra and Evangelos D. Miehelakis
I. Introduction
87
II. The Components of the Mitochondria-ROS-Kv
Axis
88
III. The Mitochondria-AOS-Kv Axis in Hypoxia: HPV
92
IV. The Mitochondria-AOS-Kv Axis, Metabolism and
Apoptosis
97
References
108
CHAPTER
6
Oxidative Modification of Ca2+ Channels, Ryanodine
Receptors, and the Sarco/Endoplasmic Reticulum
Ca2+-ATPase
Victor S. Sluirov and Christian
Schöneich
I. Introduction
114
II. Overview of Ca-+
Translocation
Membrane
Proteins
114
III. Ca2+ Channels
115
IV.
SERCA
119
V. PMC A
124
VI. Concluding Remarks
125
References
125
CHAPTER
7
Regulation of Na.K-ATPase by Reactive Oxygen
Species
Giiofci Zhou. Laura
A. Dada
and Jacob I. Sznujder
I. Na.K-ATPase
132
II. Na.K-ATPase in Alveolar Fluid
Reabsorption
133
Contents
vii
III. Role of
Reactive
Oxygen Species in Signaling
134
IV. Regulation of Na.K-ATPase and Alveolar Fluid
Reabsorption
by
ROS
136
V. Dopamine and
ß-adrenergic
Agonists Improve
ROS-Mediated Decrease in Alveolar Fluid
Reabsorption
140
VI. Summary
141
References
141
///.
RONS and Membrane Permeability
CHAPTER
8
Reactive Oxygen Species and Endothelial
Permeability
Musako
Ushio-Fukai.
Ramialt
S. ľivx,
'l'olmi
ľukui
und A\mr
II
Malik
I. Introduction
148
II.
Generation and Metabolism of
ROS
151
III. ROS
Generating System in ECs (NADPH
Oxidase)
151
IV. Regulation of Adherens Junctions
(
AJs) by
Phosphorylation and by Rho GTPase
153
V. ROS-generating Stimulants which Regulate Endothelial
Permeability
154
VI.
ROS
Reducing Factors/Proteins which Block
Endothelial Permeability
165
VII.
Molecular Targets of
ROS
Regulating Endothelial
Permeability
165
VIII.
Mediators/Regulators of ROS-dependent Endothelial
Permeability
171
IX. Functional Significance of ROS-dependent Endothelial
Permeability in Vivo
173
X. Summary and Conclusions
175
References
176
IV, RONS and Signal Transduction
CHAPTER
9
Cell Signaling by Oxidants: Pathways Leading to
Activation of Mitogen-activated Protein Kinases
(МАРК)
and Activator Protein-
1
(AP-I)
Ani
Sluikla and Brouke T. Mosumrn
I. Introduction
192
II.
МАРК
Signaling
195
VIH
Contents
III. Mitogen-activated
Protein Kinase Phosphatases
(MKPs)
198
IV. Relationships between
МАРК
and Activator Protein-
1
(AP-1)
199
V. Conclusions
203
References
204
CHAPTER
10
The Interaction of Mitochondrial Membranes with
Reactive Oxygen and Nitrogen Species
Paul S. Brookes, Andrew P. Wojtovich, Lindsay S. Burwell, David L. Hoffman
and Sergiy M. Nadtochiy
I. Mitochondria as a Source of Reactive Species
212
II. Effects of
ROS
and RNS on Mitochondrial
Respiration
217
III. Mitochondrial Membrane Lipids
221
IV.
ROS, RNS
&
Mitochondrial Ion Transport
224
V. Complex Interactions
&
Concluding Remarks
230
References
232
CHAPTER
11
Oxidant
Stress and Airway Epithelial Function
Jenora T. Waterman and Kenneth B.
Adler
I. Introduction
243
II. Sources of Reactive Oxygen Species
244
III. Antioxidant
Defenses in Airway Epithelium
245
IV. Oxidant-induced Airway Epithelial Responses
247
V. Conclusions
251
References
251
Index
257 |
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| index_date | 2024-07-02T21:45:42Z |
| indexdate | 2024-07-09T21:20:16Z |
| institution | BVB |
| isbn | 9780123738790 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016685810 |
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| series | Current topics in membranes |
| series2 | Current topics in membranes |
| spelling | Free radical effects on membranes ed. by Sadis Matalon ... 1. ed. Amsterdam [u.a.] Elsevier, Acad. Press 2008 XVIII, 262 S., [8] Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Current topics in membranes 61 Freies Radikal (DE-588)4137149-5 gnd rswk-swf Biomembran (DE-588)4006884-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Biomembran (DE-588)4006884-5 s Freies Radikal (DE-588)4137149-5 s DE-604 Matalon, Sadis Sonstige oth Current topics in membranes 61 (DE-604)BV036839511 61 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016685810&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Free radical effects on membranes Current topics in membranes Freies Radikal (DE-588)4137149-5 gnd Biomembran (DE-588)4006884-5 gnd |
| subject_GND | (DE-588)4137149-5 (DE-588)4006884-5 (DE-588)4143413-4 |
| title | Free radical effects on membranes |
| title_auth | Free radical effects on membranes |
| title_exact_search | Free radical effects on membranes |
| title_exact_search_txtP | Free radical effects on membranes |
| title_full | Free radical effects on membranes ed. by Sadis Matalon ... |
| title_fullStr | Free radical effects on membranes ed. by Sadis Matalon ... |
| title_full_unstemmed | Free radical effects on membranes ed. by Sadis Matalon ... |
| title_short | Free radical effects on membranes |
| title_sort | free radical effects on membranes |
| topic | Freies Radikal (DE-588)4137149-5 gnd Biomembran (DE-588)4006884-5 gnd |
| topic_facet | Freies Radikal Biomembran Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016685810&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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