Quantitative analysis using chromatographic techniques:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Chichester [u.a.]
Wiley
1988
|
| Ausgabe: | Reprint. |
| Schriftenreihe: | Separation science series
|
| Schlagworte: | |
| Online-Zugang: | lizenzfrei Inhaltsverzeichnis |
| Beschreibung: | XVIII, 427 S. Ill., graph. Darst. |
| ISBN: | 0471914061 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV035011865 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | t | ||
| 008 | 080820s1988 ad|| |||| 00||| eng d | ||
| 020 | |a 0471914061 |9 0-471-91406-1 | ||
| 035 | |a (OCoLC)258224395 | ||
| 035 | |a (DE-599)GBV197520006 | ||
| 040 | |a DE-604 |b ger | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-20 | ||
| 084 | |a VG 7200 |0 (DE-625)147203:253 |2 rvk | ||
| 245 | 1 | 0 | |a Quantitative analysis using chromatographic techniques |c ed. by Elena Katz |
| 250 | |a Reprint. | ||
| 264 | 1 | |a Chichester [u.a.] |b Wiley |c 1988 | |
| 300 | |a XVIII, 427 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Separation science series | |
| 650 | 0 | 7 | |a Quantitative Analyse |0 (DE-588)4125311-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Chromatographie |0 (DE-588)4010153-8 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Quantitative Analyse |0 (DE-588)4125311-5 |D s |
| 689 | 0 | 1 | |a Chromatographie |0 (DE-588)4010153-8 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Chromatographie |0 (DE-588)4010153-8 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a Katz, Elena |e Sonstige |4 oth | |
| 856 | 4 | |u http://www.gbv.de/dms/ilmenau/toc/197520006.PDF |z lizenzfrei |3 Inhaltsverzeichnis | |
| 856 | 4 | 2 | |m GBV Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016681102&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-016681102 | ||
Datensatz im Suchindex
| _version_ | 1804137933088751616 |
|---|---|
| adam_text | IMAGE 1
QUANTITATIVE ANALYSIS USING
CHROMATOGRAPHIE TECHNIQUES
EDITED BY
ELENA KATZ PERKIN EIMER, USA
JOHN WILEY & SONS
CHICHESTER * NEW YORK * BRISBANE * TORONTO * SINGAPORE
IMAGE 2
CONTENTS
CHAPTER 1. INTRODUCTION TO THE CHROMATOGRAPHIC PROCESS 1
RAYMOND P.W. SCOTT
PRINCIPLES OF A CHROMATOGRAPHIC SEPARATION 2
FACTORS THAT CONTROL SELECTIVITY 3
IONIC FORCES 4
POLAR FORCES 4
DISPERSIVE FORCES 4
METHODS OF DEVELOPMENT IN CHROMATOGRAPHY 5
FRONTAL ANALYSIS 5
ELUTION DEVELOPMENT 8
DISPLACEMENT DEVELOPMENT 9
METHODS OF ELUTION DEVELOPMENT 11
FLOW PROGRAMMING 12
TEMPERATURE PROGRAMMING 12
GRADIENT ELUTION 12
THE FUNCTION OF THE CHROMATOGRAPHIC COLUMN/THIN-LAYER PLATE 14
DISPERSION IN A PACKED COLUMN 14
THE MULTIPATH PROCESS 16
LONGITUDINAL DIFFUSION PROCESS 16
DISPERSION DUE TO RESISTANCE TO MASS TRANSFER 17
EXTRA-COLUMN DISPERSION 19
THE BASIC CHROMATOGRAPHIC SYSTEM 20
THE GAS CHROMATOGRAPH 20
THE LIQUID CHROMATOGRAPH 21
THE THIN-LAYER PLATE SYSTEM 23
THE ROLE OF THE DETECTOR 23
LINEARITY 24
SENSITIVITY 24
DETECTOR DISPERSION 26
VII
IMAGE 3
V I II
SYNOPSIS 26
REFERENCES 27
CHAPTER 2. DETECTION IN QUANTITATIVE LIQUID CHROM ATOGRAPHY 31
KENNETH OGAN
DETECTOR PERFORMANCE 31
LINEARITY 31
SENSITIVITY 32
SYSTEM NOISE 37
DATA HANDLING 38
PEAK HEIGHTS AND PEAK AREAS 39
SIGNAL DIGITIZATION 47
SOURCES OF ERROR 44
GAUSSIAN PEAKS 45
NON-GAUSSIAN PEAKS 46
BASELINE DRIFT 49
INCOMPLETE RESOLUTION 50
PEAK IDENTIFICATION 54
MULTIPLE DETECTORS 54
MULTI-CHANNEL DETECTORS 57
SYNOPSIS 59
REFERENCES 60
CHAPTER 3. QUANTITATIVE ANALYSE BY LIQUID CHROMATOGRAPHY 63
RAYMOND P.W. SCOTT
OPERATING PROCEDURES FOR QUANTITATIVE LIQUID CHROMATOGRAPHY 65
CHOICE OF DETECTORS 70
SAMPLE PREPARATION 74
INJECTION PROCEDURES 79
OPERATING CONDITIONS 80
QUANTITATIVE ANALYSIS 85
THE INTERNAL STANDARD METHOD 86
THE EXTERNAL STANDARD METHOD 87
THE NORMALIZATION METHOD 88
THE PRECISION OF MODERN LC ANALYSES 89 SYNOPSIS 95
IMAGE 4
IX
REFERENCES 97
CHAPTER 4. DETECTION IN QUANTITATIVE GAS CHROMATOGRAPHY 99
PETER C. UDEN
CLASSIFICATION OF GC DETECTORS 100
MASS SENSITIVE DETECTORS 102
CONCENTRATION SENSITIVE DETECTORS 103
UNIVERSAL DETEETION 104
SELECTIVE DETEETION 105
SPECIFIC DETEETION 105
CLASSIFICATION BASED ON THE DETECTION PROCESS 105
IONIZATION DETEETION 105
BULLE PROPERTY DETECTORS 106
SPECTROSCOPIC DETECTORS 107
ELECTROCHEMICAL DETECTORS 108
REACTION BASED DETECTORS 108
GENERAL QUANTITATIVE ASPECTS OF GC DETECTORS 109
BASELINE STABILITY 109
SIGNAL-TO-NOISE RATIO 110
MINIMUM DETECTABLE LEVEL 112
LINEAR DYNAMIC RANGE 113
STANDARDIZATION 116
DETECTION SYSTEMS AND THE INTEGRAL GAS CHROMATOGRAPH 117
PACKED AND OPEN TUBULAER COKIMNS 118
INJECTION AND SAMPLE INTRODUCTION 120
EFFECT OF DEAD VOLUME AND BAND BROADENING ON DETEETION 121
MULTIPLE DETECTORS 121
GAS CHROMATOGRAPHY DETECTORSCHARACTERISTICS AND COMPARISONS 123
ESTABLISHED, HISTORICAL AND DEVELOPMENTAL DETECTORS 123
THE THERMAL CONDUCTIVITV DETECTOR (TCD) 123 THE FLAME IONIZATION
DETECTOR 127
MODIFICATIONS TO THE FID OPERATION 129
THE ALKALI FID (AFID) 130
IMAGE 5
X
THE PHOTOIONIZATION DETECTOR (PID) 131
THE ELECTRON CAPTURE DETECTOR (ECD) 133
THE MASS SPECTROMETER DETECTOR (MSD) 134
THE INFRARED SPECTROMETER DETECTOR 136
THE FLAME PHOTOMETRIE DETECTOR (FPD) 137
THE ELECTROLYTIC (HALL) DETECTOR (HECD) 138
SPECIAL DETECTING SYSTEMS 139
THE GAS DENSITY BALANCE DETECTOR (GDBD) 139 MODIFIED THERMIONIC
IONIZATION DETECTORS (TID) 140
INERT GAS (HELIUM AND ARGON) AND UNIVERSAL IONIZATION DETECTORS 141
ATOMIC SPECTROMETER DETECTORS 142
FLAME EMISSION DETECTORS (FED) 143
ATOMIC ABSORPTION DETECTOR (AAD) 143
ATOMIC EMISSION SPECTROMETER (AED) 143 THE MICROWAVE INDUCED PLASMA
DETECTOR (MIP) 144
THE DC ARGON DETECTOR (DCP) 147
THE INDUCTIVELY COUPLED ARGON PLASMA DETECTOR (ICP) 147
THE UV ABSORPTION DETECTOR 147
THE ULTRASONIC DETECTOR (USD) 148
CHEMILUMINESCENT DETECTORS 148
SYNOPSIS 149
REFERENCES 152
CHAPTER 5. QUANTITATIVE ANALYSIS BY GAS CHROMATOGRAPHY 157
CHARLES E. REESE AND RAYMOND P.W. SCOTT
SAMPLE PREPARATION 157
SAMPLE INTRODUCTION 159
SYRINGE INJECTION 159
INJECTION VALVES 161
SOLID SAMPLE INJECTION 163
SPLIT-FLOW INJECTION 164
SPLITLESS INJECTION 166
RETENTION GAP METHOD 168
SOLUTE FOCUSSING METHOD 170
IMAGE 6
XI
RESOLUTION 172
CHOICE OF DETECTORS 175
METHODS OF PEAK AREA MEASUREMENT 177 HEIGHT X WIDTH AT HALF-HEIGHT 178
THE TRIANGULATION METHOD 179
THE PLANIMETER METHOD 180
THE CUT AND WEIGH METHOD 181
PEAK HEIGHT X RETENTION 182
PEAK HEIGHT MEASUREMENT 182
ELECTRONIC INTEGRATION 183
PROCESSING THE DATA FOR
QUANTITATIVE ANALVSIS 184
SYNOPSIS 187
REFERENCES 189
CHAPTER 6. QUANTITATIVE THIN-LAYER CHROMATOGRAPHY 193
COLIN F. POOLE AND SALWA KHATIB
INTRODUCTION 193
SAMPLE SEPARATION 196
CHROMATOGRAPHIE PERFORMANCE OF A TBINLAYER PLATE 196
CONTINUOUS SAMPLE DEVELOPMENT 201
MULTIPLE SAMPLE DEVELOPMENT 202
TWO-DIMENSIONAL SAMPLE DEVELOPMENT 209
CIRCULAR AND ANTICIRCULAR DEVELOPMENT 210
SAMPLE APPLICATION 211
SOLVENT SELECTION 212
SAMPLE APPLICATION TECHNIQUES 213
SCANNING DENSITOMETRY 218
DETECTION METHODS 218
INSTRUMENTATION FOR SCANNING DENSITOMETRY 220
PERFORMANCE OF A SCANNING DENSITOMETER 223
SENSITIVITY 225
QUALITATIVE SAMPLE IDENTIFICATION BY SCANNING DENSITOMETRY 233
THEORETICAL CONSIDERATIONS FOR QUANTITATIVE ANALYSIS 236
IMAGE 7
XII
PRACTIOAL CONSIDERATIONS FOR
QUANTITATIVE ANALYSIS 238
CALIBRATION PROCEDURES IN THE ABSORPTION MODE 238
GRAPHICAL LINEARIZATION TECHNIQUES 240
ELECTRONIC LINEARIZATION TECHNIQUES 243
CALIBRATION PROCEDURES IN THE FLUORESCENCE MODE 245
SOURCES OF ERROR IN SCANNING DENSITOMETRY 249
THE USE OF COMPUTERS IN SCANNING DENSITOMETRY 251
PHYSICAL AND CHEMICAL METHODS USED TO ENHANCE DETECTABILITY 253
LESS COMMON METHODS OF SAMPLE IDENTIFICATION AND QUANTITATION 259
SYNOPSIS 261
REFERENCES 263
CHAPTER 7. CHROMATOGRAPHY AS A QUANTITATIVE TOOL IN PHARMACEUTICAL
ANALYSIS 271
ERIC C. JENSEN
INTRODUCTION SEPARATION DEVELOPMENT SAMPLE HANDLING TECHNIQUES FACTORS
DETERMINING THE ACCURACY
AND PRECISION OF QUANTITATIVE ANALYSIS LINEARITY PRECISION
RECOVERY SPECIFICITY DETECTION LIMIT STABILITY MATRIX EFFECTS
SYSTEM SUITABILITY EXAMPLES SYNOPSIS REFERENCES
271 272 281
288 290 290 291
292 292 293 293 293
294 306 307
IMAGE 8
CHAPTER 8. IS AUTOMATION THE FUTURE OF
QUANTITATIVE CHROMATOGRAPHY? 309
G. RAYMOND MILLER
THE NEED FOR AUTOMATED SAMPLE PREPARATION SAMPLE INTRODUCTION
ANALYSIS
CHROMATOGRAPHIE OPTIMIZATION DETECTION FRACTION COLLEETION DATA ANALYSIS
AUTOSAMPLERS
SAMPLE SELECTION LC AUTOSAMPIERS GC AUTOSAMPLERS
TLC AUTOSAMPLERS COMPUTERS DATA ACQUISITION
DATA PROCESSING POST PROCESSING CONTROL INTERACTIVE CONTROL
INTERACTIVE PROBLEM SOLVING ARCHIVING COM M UNIC ATIONS ARTIFICIAL
INTELLIGENCE
RETENTION INDICIES ROBOTICS THE ROLE OF THE CHEMIST AUTOMATED LABORATORY
SYNOPSIS REFERENCES
IN THE
309 313 316 317 318
319 320 320 321 322
326 327 328 328
330 332 332 333
336 337 338 339
341 341
350 351 355
CHAPTER 9. PHYSICO-CHEMICAL INFORMATION FROM PEAK SHAPE AND WIDTH IN
LIQUID CHROMATOGRAPHY 359
ELI GRUSHKA AND SHULAMIT LEVIN
INTRODUCTION 359
IMAGE 9
XIV
DETERMINATION OF LIQUID DIFFUSION
COEFFICIENTS BY THE CHROMATOGRAPHIC BROADENING TECHNIQUES 361
THEORETICAL APPROACH 361
REQUIREMENTS FOR THE EXPERIMENTAL SYSTEM 364
SOURCES OF EXTRA-COLUMN BROADENING EFFECTS 365
ADDITIONAL SOURCES OF ERROR IN THE
MEASUREMENT OF DIFFUSION COEFFICIENTS 368
RECENT APPLICATIONS OF THE METHOD 371
ADSORPTION ISOTHERMS 374
THE CHROMATOGRAPHIE PEAK SHAPE AND ITS DEPENDENCE ON THE ADSORPTION
ISOTHERMS 379
THE LANGMUIR TYPE ISOTHERM 383
THE FREUNDLICH TYPE ISOTHERMS 385
ADSORPTION ISOTHERM AND VOID VOLUME DETERMINATIONS 387
EXPERIMENTAL MEASUREMENTS OF ISOTHERMS 390
STATIC TECHNIQUES 391
DYNAMIC TECHNIQUES CHROMATOGRAPHIE METHODS 392
FRONTAL ANALYSIS BREAKTHROUGH CURVES 392
FRONTAL ANALYSIS BY CHARACTERISTIC POINT (FACP) 393
OTHER METHODS 395
USES OF ISOTHERMS IN LIQUID CHROM ATOGRAPHY 397
SOLUTE DISTRIBUTION COEFFICIENTS 397
ELUCIDATION OF RETENTION PROCESS 397
ION PAIR CHROM ATOGRAPHY 398
ADSORPTION CHROM ATOGRAPHY 399
LIGAND EXCHANGE CHROM ATOGRAPHY 399
SYNOPSIS 400
REFERENCES 402
IMAGE 10
LIST OF SYMBOLS 411
INDEX 415
|
| adam_txt |
IMAGE 1
QUANTITATIVE ANALYSIS USING
CHROMATOGRAPHIE TECHNIQUES
EDITED BY
ELENA KATZ PERKIN EIMER, USA
JOHN WILEY & SONS
CHICHESTER * NEW YORK * BRISBANE * TORONTO * SINGAPORE
IMAGE 2
CONTENTS
CHAPTER 1. INTRODUCTION TO THE CHROMATOGRAPHIC PROCESS 1
RAYMOND P.W. SCOTT
PRINCIPLES OF A CHROMATOGRAPHIC SEPARATION 2
FACTORS THAT CONTROL SELECTIVITY 3
IONIC FORCES 4
POLAR FORCES 4
DISPERSIVE FORCES 4
METHODS OF DEVELOPMENT IN CHROMATOGRAPHY 5
FRONTAL ANALYSIS 5
ELUTION DEVELOPMENT 8
DISPLACEMENT DEVELOPMENT 9
METHODS OF ELUTION DEVELOPMENT 11
FLOW PROGRAMMING 12
TEMPERATURE PROGRAMMING 12
GRADIENT ELUTION 12
THE FUNCTION OF THE CHROMATOGRAPHIC COLUMN/THIN-LAYER PLATE 14
DISPERSION IN A PACKED COLUMN 14
THE MULTIPATH PROCESS 16
LONGITUDINAL DIFFUSION PROCESS 16
DISPERSION DUE TO RESISTANCE TO MASS TRANSFER 17
EXTRA-COLUMN DISPERSION 19
THE BASIC CHROMATOGRAPHIC SYSTEM 20
THE GAS CHROMATOGRAPH 20
THE LIQUID CHROMATOGRAPH 21
THE THIN-LAYER PLATE SYSTEM 23
THE ROLE OF THE DETECTOR 23
LINEARITY 24
SENSITIVITY 24
DETECTOR DISPERSION 26
VII
IMAGE 3
V I II
SYNOPSIS 26
REFERENCES 27
CHAPTER 2. DETECTION IN QUANTITATIVE LIQUID CHROM ATOGRAPHY 31
KENNETH OGAN
DETECTOR PERFORMANCE 31
LINEARITY 31
SENSITIVITY 32
SYSTEM NOISE 37
DATA HANDLING 38
PEAK HEIGHTS AND PEAK AREAS 39
SIGNAL DIGITIZATION 47
SOURCES OF ERROR 44
GAUSSIAN PEAKS 45
NON-GAUSSIAN PEAKS 46
BASELINE DRIFT 49
INCOMPLETE RESOLUTION 50
PEAK IDENTIFICATION 54
MULTIPLE DETECTORS 54
MULTI-CHANNEL DETECTORS 57
SYNOPSIS 59
REFERENCES 60
CHAPTER 3. QUANTITATIVE ANALYSE BY LIQUID CHROMATOGRAPHY 63
RAYMOND P.W. SCOTT
OPERATING PROCEDURES FOR QUANTITATIVE LIQUID CHROMATOGRAPHY 65
CHOICE OF DETECTORS 70
SAMPLE PREPARATION 74
INJECTION PROCEDURES 79
OPERATING CONDITIONS 80
QUANTITATIVE ANALYSIS 85
THE INTERNAL STANDARD METHOD 86
THE EXTERNAL STANDARD METHOD 87
THE NORMALIZATION METHOD 88
THE PRECISION OF MODERN LC ANALYSES 89 SYNOPSIS 95
IMAGE 4
IX
REFERENCES 97
CHAPTER 4. DETECTION IN QUANTITATIVE GAS CHROMATOGRAPHY 99
PETER C. UDEN
CLASSIFICATION OF GC DETECTORS 100
MASS SENSITIVE DETECTORS 102
CONCENTRATION SENSITIVE DETECTORS 103
UNIVERSAL DETEETION 104
SELECTIVE DETEETION 105
SPECIFIC DETEETION 105
CLASSIFICATION BASED ON THE DETECTION PROCESS 105
IONIZATION DETEETION 105
BULLE PROPERTY DETECTORS 106
SPECTROSCOPIC DETECTORS 107
ELECTROCHEMICAL DETECTORS 108
REACTION BASED DETECTORS 108
GENERAL QUANTITATIVE ASPECTS OF GC DETECTORS 109
BASELINE STABILITY 109
SIGNAL-TO-NOISE RATIO 110
MINIMUM DETECTABLE LEVEL 112
LINEAR DYNAMIC RANGE 113
STANDARDIZATION 116
DETECTION SYSTEMS AND THE INTEGRAL GAS CHROMATOGRAPH 117
PACKED AND OPEN TUBULAER COKIMNS 118
INJECTION AND SAMPLE INTRODUCTION 120
EFFECT OF DEAD VOLUME AND BAND BROADENING ON DETEETION 121
MULTIPLE DETECTORS 121
GAS CHROMATOGRAPHY DETECTORSCHARACTERISTICS AND COMPARISONS 123
ESTABLISHED, HISTORICAL AND DEVELOPMENTAL DETECTORS 123
THE THERMAL CONDUCTIVITV DETECTOR (TCD) 123 THE FLAME IONIZATION
DETECTOR 127
MODIFICATIONS TO THE FID OPERATION 129
THE ALKALI FID (AFID) 130
IMAGE 5
X
THE PHOTOIONIZATION DETECTOR (PID) 131
THE ELECTRON CAPTURE DETECTOR (ECD) 133
THE MASS SPECTROMETER DETECTOR (MSD) 134
THE INFRARED SPECTROMETER DETECTOR 136
THE FLAME PHOTOMETRIE DETECTOR (FPD) 137
THE ELECTROLYTIC (HALL) DETECTOR (HECD) 138
SPECIAL DETECTING SYSTEMS 139
THE GAS DENSITY BALANCE DETECTOR (GDBD) 139 MODIFIED THERMIONIC
IONIZATION DETECTORS (TID) 140
INERT GAS (HELIUM AND ARGON) AND UNIVERSAL IONIZATION DETECTORS 141
ATOMIC SPECTROMETER DETECTORS 142
FLAME EMISSION DETECTORS (FED) 143
ATOMIC ABSORPTION DETECTOR (AAD) 143
ATOMIC EMISSION SPECTROMETER (AED) 143 THE MICROWAVE INDUCED PLASMA
DETECTOR (MIP) 144
THE DC ARGON DETECTOR (DCP) 147
THE INDUCTIVELY COUPLED ARGON PLASMA DETECTOR (ICP) ' 147
THE UV ABSORPTION DETECTOR 147
THE ULTRASONIC DETECTOR (USD) 148
CHEMILUMINESCENT DETECTORS 148
SYNOPSIS 149
REFERENCES 152
CHAPTER 5. QUANTITATIVE ANALYSIS BY GAS CHROMATOGRAPHY 157
CHARLES E. REESE AND RAYMOND P.W. SCOTT
SAMPLE PREPARATION 157
SAMPLE INTRODUCTION 159
SYRINGE INJECTION 159
INJECTION VALVES 161
SOLID SAMPLE INJECTION 163
SPLIT-FLOW INJECTION 164
SPLITLESS INJECTION 166
RETENTION GAP METHOD 168
SOLUTE FOCUSSING METHOD 170
IMAGE 6
XI
RESOLUTION 172
CHOICE OF DETECTORS 175
METHODS OF PEAK AREA MEASUREMENT 177 HEIGHT X WIDTH AT HALF-HEIGHT 178
THE TRIANGULATION METHOD ' 179
THE PLANIMETER METHOD 180
THE CUT AND WEIGH METHOD 181
PEAK HEIGHT X RETENTION 182
PEAK HEIGHT' MEASUREMENT 182
ELECTRONIC INTEGRATION 183
PROCESSING THE DATA FOR
QUANTITATIVE ANALVSIS 184
SYNOPSIS ' 187
REFERENCES 189
CHAPTER 6. QUANTITATIVE THIN-LAYER CHROMATOGRAPHY 193
COLIN F. POOLE AND SALWA KHATIB
INTRODUCTION 193
SAMPLE SEPARATION 196
CHROMATOGRAPHIE PERFORMANCE OF A TBINLAYER PLATE 196
CONTINUOUS SAMPLE DEVELOPMENT 201
MULTIPLE SAMPLE DEVELOPMENT 202
TWO-DIMENSIONAL SAMPLE DEVELOPMENT 209
CIRCULAR AND ANTICIRCULAR DEVELOPMENT 210
SAMPLE APPLICATION " 211
SOLVENT SELECTION 212
SAMPLE APPLICATION TECHNIQUES 213
SCANNING DENSITOMETRY 218
DETECTION METHODS 218
INSTRUMENTATION FOR SCANNING DENSITOMETRY 220
PERFORMANCE OF A SCANNING DENSITOMETER 223
SENSITIVITY 225
QUALITATIVE SAMPLE IDENTIFICATION BY SCANNING DENSITOMETRY 233
THEORETICAL CONSIDERATIONS FOR QUANTITATIVE ANALYSIS 236
IMAGE 7
XII
PRACTIOAL CONSIDERATIONS FOR
QUANTITATIVE ANALYSIS 238
CALIBRATION PROCEDURES IN THE ABSORPTION MODE 238
GRAPHICAL LINEARIZATION TECHNIQUES 240
ELECTRONIC LINEARIZATION TECHNIQUES 243
CALIBRATION PROCEDURES IN THE FLUORESCENCE MODE 245
SOURCES OF ERROR IN SCANNING DENSITOMETRY 249
THE USE OF COMPUTERS IN SCANNING DENSITOMETRY 251
PHYSICAL AND CHEMICAL METHODS USED TO ENHANCE DETECTABILITY 253
LESS COMMON METHODS OF SAMPLE IDENTIFICATION AND QUANTITATION 259
SYNOPSIS 261
REFERENCES 263
CHAPTER 7. CHROMATOGRAPHY AS A QUANTITATIVE TOOL IN PHARMACEUTICAL
ANALYSIS 271
ERIC C. JENSEN
INTRODUCTION SEPARATION DEVELOPMENT SAMPLE HANDLING TECHNIQUES FACTORS
DETERMINING THE ACCURACY
AND PRECISION OF QUANTITATIVE ANALYSIS LINEARITY PRECISION
RECOVERY SPECIFICITY DETECTION LIMIT STABILITY MATRIX EFFECTS
SYSTEM SUITABILITY EXAMPLES SYNOPSIS REFERENCES
271 272 281
288 290 290 291
292 292 293 293 293
294 306 307
IMAGE 8
CHAPTER 8. IS AUTOMATION THE FUTURE OF
QUANTITATIVE CHROMATOGRAPHY? 309
G. RAYMOND MILLER
THE NEED FOR AUTOMATED SAMPLE PREPARATION SAMPLE INTRODUCTION
ANALYSIS
CHROMATOGRAPHIE OPTIMIZATION DETECTION FRACTION COLLEETION DATA ANALYSIS
AUTOSAMPLERS
SAMPLE SELECTION LC AUTOSAMPIERS GC AUTOSAMPLERS
TLC AUTOSAMPLERS COMPUTERS DATA ACQUISITION
DATA PROCESSING POST PROCESSING CONTROL INTERACTIVE CONTROL
INTERACTIVE PROBLEM SOLVING ARCHIVING COM M UNIC ATIONS ARTIFICIAL
INTELLIGENCE
RETENTION INDICIES ROBOTICS THE ROLE OF THE CHEMIST AUTOMATED LABORATORY
SYNOPSIS REFERENCES
IN THE
309 313 316 317 318
319 320 320 321 322
326 327 328 328
330 332 332 333
336 337 338 339
341 341
350 351 355
CHAPTER 9. PHYSICO-CHEMICAL INFORMATION FROM PEAK SHAPE AND WIDTH IN
LIQUID CHROMATOGRAPHY 359
ELI GRUSHKA AND SHULAMIT LEVIN
INTRODUCTION 359
IMAGE 9
XIV
DETERMINATION OF LIQUID DIFFUSION
COEFFICIENTS BY THE CHROMATOGRAPHIC BROADENING TECHNIQUES 361
THEORETICAL APPROACH 361
REQUIREMENTS FOR THE EXPERIMENTAL SYSTEM 364
SOURCES OF EXTRA-COLUMN BROADENING EFFECTS 365
ADDITIONAL SOURCES OF ERROR IN THE
MEASUREMENT OF DIFFUSION COEFFICIENTS 368
RECENT APPLICATIONS OF THE METHOD 371
ADSORPTION ISOTHERMS 374
THE CHROMATOGRAPHIE PEAK SHAPE AND ITS DEPENDENCE ON THE ADSORPTION
ISOTHERMS 379
THE LANGMUIR TYPE ISOTHERM 383
THE FREUNDLICH TYPE ISOTHERMS 385
ADSORPTION ISOTHERM AND VOID VOLUME DETERMINATIONS 387
EXPERIMENTAL MEASUREMENTS OF ISOTHERMS 390
STATIC TECHNIQUES 391
DYNAMIC TECHNIQUES CHROMATOGRAPHIE METHODS 392
FRONTAL ANALYSIS BREAKTHROUGH CURVES 392
FRONTAL ANALYSIS BY CHARACTERISTIC POINT (FACP) 393
OTHER METHODS 395
USES OF ISOTHERMS IN LIQUID CHROM ATOGRAPHY 397
SOLUTE DISTRIBUTION COEFFICIENTS 397
ELUCIDATION OF RETENTION PROCESS 397
ION PAIR CHROM ATOGRAPHY 398
ADSORPTION CHROM ATOGRAPHY 399
LIGAND EXCHANGE CHROM ATOGRAPHY 399
SYNOPSIS 400
REFERENCES 402
IMAGE 10
LIST OF SYMBOLS 411
INDEX 415 |
| any_adam_object | 1 |
| any_adam_object_boolean | 1 |
| building | Verbundindex |
| bvnumber | BV035011865 |
| classification_rvk | VG 7200 |
| ctrlnum | (OCoLC)258224395 (DE-599)GBV197520006 |
| discipline | Chemie / Pharmazie |
| discipline_str_mv | Chemie / Pharmazie |
| edition | Reprint. |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01529nam a2200397 c 4500</leader><controlfield tag="001">BV035011865</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">080820s1988 ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0471914061</subfield><subfield code="9">0-471-91406-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)258224395</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBV197520006</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-20</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VG 7200</subfield><subfield code="0">(DE-625)147203:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Quantitative analysis using chromatographic techniques</subfield><subfield code="c">ed. by Elena Katz</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">Reprint.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Chichester [u.a.]</subfield><subfield code="b">Wiley</subfield><subfield code="c">1988</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XVIII, 427 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Separation science series</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Quantitative Analyse</subfield><subfield code="0">(DE-588)4125311-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Chromatographie</subfield><subfield code="0">(DE-588)4010153-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Quantitative Analyse</subfield><subfield code="0">(DE-588)4125311-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Chromatographie</subfield><subfield code="0">(DE-588)4010153-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Chromatographie</subfield><subfield code="0">(DE-588)4010153-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Katz, Elena</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2=" "><subfield code="u">http://www.gbv.de/dms/ilmenau/toc/197520006.PDF</subfield><subfield code="z">lizenzfrei</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">GBV Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016681102&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-016681102</subfield></datafield></record></collection> |
| id | DE-604.BV035011865 |
| illustrated | Illustrated |
| index_date | 2024-07-02T21:44:05Z |
| indexdate | 2024-07-09T21:20:10Z |
| institution | BVB |
| isbn | 0471914061 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016681102 |
| oclc_num | 258224395 |
| open_access_boolean | |
| owner | DE-20 |
| owner_facet | DE-20 |
| physical | XVIII, 427 S. Ill., graph. Darst. |
| publishDate | 1988 |
| publishDateSearch | 1988 |
| publishDateSort | 1988 |
| publisher | Wiley |
| record_format | marc |
| series2 | Separation science series |
| spelling | Quantitative analysis using chromatographic techniques ed. by Elena Katz Reprint. Chichester [u.a.] Wiley 1988 XVIII, 427 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Separation science series Quantitative Analyse (DE-588)4125311-5 gnd rswk-swf Chromatographie (DE-588)4010153-8 gnd rswk-swf Quantitative Analyse (DE-588)4125311-5 s Chromatographie (DE-588)4010153-8 s DE-604 Katz, Elena Sonstige oth http://www.gbv.de/dms/ilmenau/toc/197520006.PDF lizenzfrei Inhaltsverzeichnis GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016681102&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Quantitative analysis using chromatographic techniques Quantitative Analyse (DE-588)4125311-5 gnd Chromatographie (DE-588)4010153-8 gnd |
| subject_GND | (DE-588)4125311-5 (DE-588)4010153-8 |
| title | Quantitative analysis using chromatographic techniques |
| title_auth | Quantitative analysis using chromatographic techniques |
| title_exact_search | Quantitative analysis using chromatographic techniques |
| title_exact_search_txtP | Quantitative analysis using chromatographic techniques |
| title_full | Quantitative analysis using chromatographic techniques ed. by Elena Katz |
| title_fullStr | Quantitative analysis using chromatographic techniques ed. by Elena Katz |
| title_full_unstemmed | Quantitative analysis using chromatographic techniques ed. by Elena Katz |
| title_short | Quantitative analysis using chromatographic techniques |
| title_sort | quantitative analysis using chromatographic techniques |
| topic | Quantitative Analyse (DE-588)4125311-5 gnd Chromatographie (DE-588)4010153-8 gnd |
| topic_facet | Quantitative Analyse Chromatographie |
| url | http://www.gbv.de/dms/ilmenau/toc/197520006.PDF http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016681102&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT katzelena quantitativeanalysisusingchromatographictechniques |