The motoneurone and its muscle fibres:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
2006
|
| Schriftenreihe: | Monographs of the Physiological Society
50 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 341 S. Ill., graph. Darst |
| ISBN: | 0198526555 9780198526551 |
Internformat
MARC
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| 100 | 1 | |a Kernell, Daniel |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a The motoneurone and its muscle fibres |c Daniel Kernell |
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 2006 | |
| 300 | |a XII, 341 S. |b Ill., graph. Darst | ||
| 336 | |b txt |2 rdacontent | ||
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| 490 | 1 | |a Monographs of the Physiological Society |v 50 | |
| 650 | 4 | |a Motor neurons | |
| 650 | 4 | |a Neuromuscular transmission | |
| 650 | 4 | |a Muscles | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-022117503 | ||
Datensatz im Suchindex
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| adam_text | Contents
Abbreviations xi
1 Why bother about motoneurones? 01
1.1 General layout and functions of the vertebrate neuromuscular system 0/
1.2 Motoneurones as model neurones 03
1.3 What will readers find where? 04
2 Basic neuromuscular properties 05
2.1 Introduction 05
2.2 Skeletal muscles and peripheral nerves 05
2.3 Muscle innervation 09
2.4 Physiology of peripheral axons 12
2.5 Muscle electrophysiology and excitation-contraction coupling 21
2.6 Muscle metabolism 23
2.7 Specializations of muscle fibre and motor unit properties 24
2.8 CNS control of motor behaviour 25
3 Muscle unit properties and specializations 29
3.1 General issues 29
3.2 Muscle heterogeneity: early observations and the progress of insights 29
3.3 Contractile properties 30
3.4 Cytochemistry 51
3.5 Muscle unit and fibre classification: relationships and predictions 58
3.6 Distribution and topographical organization of fibre types 59
3.7 Motor axons and muscle innervation 63
4 Neuromuscular transmission 67
4.1 General issues 67
4.2 Morphology and molecular organization 67
4.3 Transmitter release and postsynaptic action 70
4.4 Physiology of neuromuscular spike transmission 75
4.5 Pathophysiological issues 77
5 Motoneurones: morphology, cytology, and topographical organization 79
5.1 General issues 79
5.2 Motoneuronal morphology 79
5.3 Motoneuronal cytology and cell biology 88
5.4 Motoneurone populations innervating different muscles and muscle fibres 92
5.5 Pathophysiological issue: vulnerability of large versus small motoneurones 95
iii I CONTENTS
6 Motoneurones: electrophysiology 97
6.1 General issues 97
6.2 Motoneurone action potentials: regional differences in excitability 97
6.3 Depolarizing and hyperpolarizing after-potentials 99
6.4 Voltage responses to subthreshold steps of injected current 101
6.5 Current-to-frequency transduction: baseline properties 105
6.6 Current-to-frequency transduction: discussion of mechanisms 112
6.7 Persistent inward currents (PICs) 117
6.8 Ion channels of the soma-dendrite membrane 120
6.9 Differentiation of motoneurone characteristics in relation to
muscle fibre properties 123
6.10 Pathophysiological issue: motoneurone disease 132
7 Motoneurones: synaptic control 135
7.1 General issues 135
7.2 Individual synapses: cytology and physiology 135
7.3 Postsynaptic currents driving repetitive spike discharges 147
7.4 Available amount of postsynaptic driving current in motoneurones 151
7.5 Motoneurone-modifying synapses and their effects
on motoneurone firing 153
7.6 Innervation of motoneurones controlling different
categories of muscle unit 156
8 Motoneurone populations and the gradation of muscle force 159
8.1 General issues 159
8.2 Recruitment gradation in motoneurone pools 159
8.3 Rate gradation in motoneurone pools 168
8.4 Force gradation: recruitment and rate gradation combined 170
8.5 Renshaw inhibition: a system for synaptic pool feedback 176
8.6 Pathophysiological issue: imitating the action of motoneurone
pools in functional electrical stimulation 180
9 Short-term plasticity: fatigue and potentiation 183
9.1 General issues 183
9.2 What do we mean by fatigue? 183
9.3 Peripheral versus central fatigue 186
9.4 Manifestations of peripheral motor fatigue 188
9.5 Components of peripheral motor fatigue 189
9.6 Motoneurone-associated components of central motor fatigue 193
9.7 Neuromuscular features alleviating motor fatigue 198
9.8 Motor potentiation and facilitation 199
9.9 Clinical and applied aspects of fatigue 202
CONTENTS |
10 Denervation and reinnervation 203
10.1 General issues 203
10.2 Reactions of motoneurones to transection of their axons 203
10.3 Peripheral reactions to loss or damage of motor axons 209
10.4 Muscle reinnervation 214
10.5 Sprouting and collateral reinnervation 223
10.6 Pathophysiological issues 224
11 Long-term plasticity 227
11.1 General issues 227
11.2 Methods of studying use-related plasticity in
the neuromuscular system 227
11.3 Plasticity of muscle properties 231
11.4 Plasticity of motoneurone properties 248
11.5 Pathophysiological issue: motoneurone-muscle interactions
in disease 258
12 Genetic specification and lifespan development 259
12.1 General issues 259
12.2 The classical initial stages of development 260
12.3 Differentiation into motoneurones and interneurones 260
12.4 Differentiation into different categories of motoneurones 262
12.5 Myotube generations and muscle fibre differentiation 263
12.6 Outgrowth of motoneurone axons and programmed
motoneurone death 264
12.7 Formation of neuromuscular junctions 266
12.8 From poly- to mononeuronal muscle fibre innervation 266
12.9 Early changes in motoneurone electrophysiology and muscle speed 268
12.10 Postnatal motoneurone morphology 269
12.11 Postnatal neuromuscular use and differentiation 269
12.12 Neuromuscular ageing 270
12.13 Applied issue: how to make motoneurones 272
Copyright acknowledgements 273
References 275
Index 335
|
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| dewey-ones | 612 - Human physiology |
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| dewey-search | 612.7 |
| dewey-sort | 3612.7 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
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| id | DE-604.BV026555083 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T23:14:48Z |
| institution | BVB |
| isbn | 0198526555 9780198526551 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-022117503 |
| oclc_num | 255371854 |
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| physical | XII, 341 S. Ill., graph. Darst |
| publishDate | 2006 |
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| publisher | Oxford Univ. Press |
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| series2 | Monographs of the Physiological Society |
| spelling | Kernell, Daniel Verfasser aut The motoneurone and its muscle fibres Daniel Kernell Oxford [u.a.] Oxford Univ. Press 2006 XII, 341 S. Ill., graph. Darst txt rdacontent n rdamedia nc rdacarrier Monographs of the Physiological Society 50 Motor neurons Neuromuscular transmission Muscles Muskelfaser (DE-588)4170854-4 gnd rswk-swf Motoneuron (DE-588)4135747-4 gnd rswk-swf Motoneuron (DE-588)4135747-4 s Muskelfaser (DE-588)4170854-4 s DE-188 Physiological Society <Great Britain> Monographs of the Physiological Society 50 (DE-604)BV024825803 50 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022117503&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Kernell, Daniel The motoneurone and its muscle fibres Motor neurons Neuromuscular transmission Muscles Muskelfaser (DE-588)4170854-4 gnd Motoneuron (DE-588)4135747-4 gnd |
| subject_GND | (DE-588)4170854-4 (DE-588)4135747-4 |
| title | The motoneurone and its muscle fibres |
| title_auth | The motoneurone and its muscle fibres |
| title_exact_search | The motoneurone and its muscle fibres |
| title_full | The motoneurone and its muscle fibres Daniel Kernell |
| title_fullStr | The motoneurone and its muscle fibres Daniel Kernell |
| title_full_unstemmed | The motoneurone and its muscle fibres Daniel Kernell |
| title_short | The motoneurone and its muscle fibres |
| title_sort | the motoneurone and its muscle fibres |
| topic | Motor neurons Neuromuscular transmission Muscles Muskelfaser (DE-588)4170854-4 gnd Motoneuron (DE-588)4135747-4 gnd |
| topic_facet | Motor neurons Neuromuscular transmission Muscles Muskelfaser Motoneuron |
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