Ergometry in hypertensive patients: implications for diagnosis and treatment
Gespeichert in:
1. Verfasser: | |
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Format: | Abschlussarbeit Buch |
Sprache: | English |
Veröffentlicht: |
Berlin ; Heidelberg ; New York ; Tokyo
Springer
1986
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | Dt. Ausg. u.d.T.: Franz, Ingomar-Werner: Ergometrie bei Hochdruckkranken. - Mit |
Beschreibung: | XVIII, 228 S. Ill., graph. Darst. |
ISBN: | 3540153225 0387153225 |
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240 | 1 | 0 | |a Ergometrie bei Hochdruckkranken |
245 | 1 | 0 | |a Ergometry in hypertensive patients |b implications for diagnosis and treatment |c Ingomar-Werner Franz. Transl. by Terry Telger. Foreword by P. Schölmerich |
246 | 1 | 3 | |a Ergometrische Untersuchungen zur Diasgnostik und Therapiekontrolle bei der arteriellen Hypertonie |
264 | 1 | |a Berlin ; Heidelberg ; New York ; Tokyo |b Springer |c 1986 | |
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500 | |a Dt. Ausg. u.d.T.: Franz, Ingomar-Werner: Ergometrie bei Hochdruckkranken. - Mit | ||
502 | |a Berlin, Freie Univ., Habil.-Schr. 1981 u.d.T.: Franz, Ingomar-Werner: Ergometrische Untersuchungen zur Diasgnostik und Therapiekontrolle bei der arteriellen Hypertonie | ||
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adam_text | TABLE OF CONTENTS
I. METHODOLOGY 1
1. PRINCIPLES OF ERGOMETRY 1
1.1. METHODOLOGIC PRINCIPLES 1
1.1.1. PHYSICAL PRINCIPLES 1
1.1.2. EXERCISE STAGES AND WORKLOAD INCREMENTS 2
1.1.3. STANDARDS FOR ERGOMETRIC TESTING 5
1.2. PHYSIOLOGY AND PATHOPHYSIOLOGY OF ERGOMETRY .... 6
1.2.1. HEMODYNAMIC CHANGES 6
1.2.2. ARTERIAL WALL CHANGES 7
2. BLOOD PRESSURE MEASUREMENT DURING ERGOMETRY ... 8
2.1. STUDY POPULATION 8
2.2. TEST METHODOLOGY 8
2.2.1. THE ERGOMETER 8
2.2.2. EXERCISE STAGES AND WORKLOAD INCREMENTS 9
2.3. HEART RATE MEASUREMENT 10
2.4. BLOOD PRESSURE MEASUREMENT 10
2.5. COMPARISON OF DIRECT AND INDIRECT BLOOD PRESSURE
MEASUREMENTS 11
2.6. ENVIRONMENTAL SPECIFICATIONS AND TEST PREPARATIONS . 14
II.
ERGOMETRY
AS AN AID
TO DIAGNOSIS 15
1. STATEMENT OF PROBLEM 15
2. BLOOD PRESSURE AND HEART RATE RESPONSES OF NORMAL
INDIVIDUALS 20
2.1. BLOOD PRESSURE RESPONSES OF MEN 20-50 YEARS OF AGE 20
2.1.1. STUDY POPULATION 20
2.1.2. RESTING BLOOD PRESSURE . 22
2.1.3. BLOOD PRESSURE DURING ERGOMETRY 23
2.1.4. BLOOD PRESSURE DURING RECOVERY 23
2.1.5. HEART RATE BEFORE, DURING AND AFTER ERGOMETRY .... 24
2.2. BLOOD PRESSURE AND HEART RATE RESPONSES OF MEN
55-80 YEARS OF AGE 25
HTTP://D-NB.INFO/850797160
XIV TABLE OF CONTENTS
2.2.1. STUDY POPULATION 25
2.2.2. RESTING BLOOD PRESSURE 27
2.2.3. BLOOD PRESSURE DURING ERGOMETRY 27
2.2.4. BLOOD PRESSURE DURING RECOVERY 28
2.2.5. HEART RATE BEFORE, DURING AND AFTER ERGOMETRY .... 28
2.3. BLOOD PRESSURE AND HEART RATE RESPONSES OF WOMEN
20-50 YEARS OF AGE 28
2.3.1. STUDY POPULATION 28
2.3.2. RESTING BLOOD PRESSURE 29
2.3.3. BLOOD PRESSURE DURING ERGOMETRY 29
2.3.4. BLOOD PRESSURE DURING RECOVERY 31
2.3.5. HEART RATE BEFORE, DURING AND AFTER ERGOMETRY .... 31
2.4. COMPARATIVE ASSESSMENT OF THE BLOOD PRESSURE
RESPONSES
OF NORMOTENSIVE
MEN
AND
WOMEN .... 33
2.5. PRACTICAL UTILIZATION OF NORMAL VALUES 34
2.6. CORRELATIVE ASSESSMENT OF DIASTOLIC BLOOD PRESSURES
BEFORE, DURING AND AFTER ERGOMETRY 37
3. BLOOD PRESSURE AND HEART RESPONSES OF HYPERTENSIVE
PATIENTS 38
3.1. REPRODUCIBILITY OF BLOOD PRESSURE AND HEART RATE
RESPONSES DURING AND AFTER ERGOMETRY 38
3.1.1. HYPERTENSIVES 38
3.1.2. BORDERLINE HYPERTENSIVES 41
3.2. COMPARISON OF HYPERTENSIVE MALES VARYING IN AGE
AND SEVERITY OF BLOOD PRESSURE ELEVATION 44
3.2.1. PATIENTS 44
3.2.2. AGE COMPARISON OF HYPERTENSIVES WITH BLOOD
PRESSURES BELOW 170/105 MM HG 45
3.2.3. AGE COMPARISON IN HYPERTENSIVES WITH BLOOD
PRESSURES ABOVE 170/105 MM HG 47
3.2.4. HYPERTENSIVES OF EQUAL AGE BUT WITH DIFFERENT
SEVERITIES OF BLOOD PRESSURE ELEVATION 49
3.3. COMPARISON OF HYPERTENSIVE FEMALES OF VARYING
AGES 50
3.3.1. PATIENTS 50
3.3.2. BLOOD PRESSURE AND HEART RATE RESPONSES 50
3.4. SUMMARY AND CORTCLUSIONS 53
3.4.1. MEAN SYSTOLIC AND DIASTOLIC BLOOD PRESSURE
RESPONSES 53
3.4.2. REPRODUCIBILITY OF THE BLOOD PRESSURE 54
3.4.3. ANALYSIS OF BLOOD PRESSURE RESPONSES BY
HEMODYNAMIC REACTION TYPE 56
3.4.4. ANALYSIS OF THE UPPER NORMOTENSIVE LIMIT 56
3.4.5. INDIVIDUAL BLOOD PRESSURE RESPONSE 58
4. BLOOD PRESSURE AND HEART RATE RESPONSES OF
BORDERLINE HYPERTENSIVES 63
TABLE OF CONTENTS XV
4.1. BLOOD PRESSURE AND HEART RATE RESPONSES OF MEN
20-50 YEARS OF AGE 64
4.1.1. PATIENTS 64
4.1.2. BLOOD PRESSURE AND HEART RATE RESPONSES 64
4.2. COMPARATIVE STUDY OF BORDERLINE HYPERTENSIVES,
DEFINITE HYPERTENSIVES AND NORMOTENSIVES OF EQUAL
AGE DISTRIBUTION 68
4.2.1. STUDY POPULATION 68
4.2.2. BLOOD PRESSURE AND HEART RATE RESPONSES 68
4.3. FOLLOW-UP OF THE BORDERLINE HYPERTENSIVES AT
3.8 YEARS 73
4.3.1. PATIENTS 73
4.3.2. FOLLOW-UP OF THE EXERCISE-POSITIVE BORDERLINE
HYPERTENSIVES 75
4.3.3. EXERCISE-NEGATIVE BORDERLINE HYPERTENSIVES .... 78
4.4. RESTING BLOOD PRESSURES OF BORDERLINE HYPERTENSIVES
COMPARED WITH HYPERTENSIVES AND NORMOTENSIVES . . 81
4.4.1. ORTHOSTATICS 81
4.4.2. EMOTIONAL INFLUENCES 83
4.5. SUMMARY AND CONCLUSIONS 83
4.5.1. PREVALENCE AND COURSE OF BORDERLINE HYPERTENSION . . 83
4.5.2. THE EARLY DIAGNOSIS OF HYPERTENSION IN BORDERLINE
PATIENTS 84
4.5.3. PROGNOSTIC EVALUATION OF BORDERLINE HYPERTENSION . . 89
4.5.4. THERAPEUTIC IMPLICATIONS 89
5. BLOOD PRESSURE INCREMENTS FROM REST TO EXERCISE IN
NORMOTENSIVES, BORDERLINE HYPERTENSIVES AND
HYPERTENSIVES
91
5.1. RESULTS AND COMPARISON WITH INVASIVE
MEASUREMENTS 91
5.2. SUMMARY AND CONCLUSIONS 96
6. BLOOD PRESSURE AND HEART RATE RESPONSES OF ELDERLY
HYPERTENSIVES 96
6.1. COMPARATIVE STUDY OF ELDERLY HYPERTENSIVES AND
NORMOTENSIVES OF EQUAL AGE DISTRIBUTION 97
6.1.1. STUDY POPULATION 97
6.1.2. BLOOD PRESSURE AND HEART RATE RESPONSES 97
6.2. SUMMARY AND CONCLUSIONS 102
6.2.1. PREVALENCE 102
6.2.2. PROGNOSIS 103
6.2.3. DIAGNOSTIC ASSESSMENT 103
6.2.4. THERAPEUTIC IMPLICATIONS 105
7. ERGOMETRY FOR ASSESSING THE MYOCARDIAL OXYGEN
CONSUMPTION AND CARDIOCORPOREAL PERFORMANCE
CAPACITY OF HYPERTENSIVE PATIENTS 106
XVI TABLE OF CONTENTS
7.1. COMPARATIVE DETERMINATION OF THE RATE-PRESSURE
PRODUCT OF HYPERTENSIVES AND NORMOTENSIVES 106
7.1.1. STUDY POPULATION 106
7.1.2. RATE-PRESSURE PRODUCT OF YOUNGER HYPERTENSIVES,
BORDERLINE HYPERTENSIVES AND NORMOTENSIVES 107
7.1.3. RATE-PRESSURE PRODUCT OF ELDERLY HYPERTENSIVES AND
NORMOTENSIVES 108
7.2. COMPARATIVE DETERMINATION OF THE PHYSICAL WORK
CAPACITY 170 OF HYPERTENSIVES AND NORMOTENSIVES . .108
7.2.1. STUDY POPULATION 109
7.2.2. PWC170 OF HYPERTENSIVES, NORMOTENSIVES AND
BORDERLINE HYPERTENSIVES 109
7.3. ASSESSMENT OF MYOCARDIAL OXYGEN CONSUMPTION AND
CARDIOCORPOREAL PERFORMANCE CAPACITY 110
7.3.1. PROGNOSTIC SIGNIFICANCE OF THE MYOCARDIAL OXYGEN
CONSUMPTION 110
7.3.2. ECONOMIZATION THROUGH ENDURANCE TRAINING ILL
7.3.3. PRESCRIBING PHYSICAL TRAINING IN HYPERTENSIVE PATIENTS 113
III.
ERGOMETRY
AS AN AID
TO PATIENT MANAGEMENT 117
1. IMPORTANCE OF EXERCISE BLOOD PRESSURES AS A VASCULAR
RISK FACTOR 117
1.1. DEVELOPMENT OF ATHEROSCLEROSIS IN ARTERIAL
HYPERTENSION 117
1.2. SEVERITY OF STRESS-INDUCED BLOOD PRESSURE ELEVATIONS
AND THEIR EVALUATION 118
1.3. PROGNOSIS OF ACUTE AND CHRONIC COMPLICATIONS .... 121
1.4. THE PRESSOR RESPONSE TO STRESS AS A CAUSAL FACTOR IN
CHRONIC HYPERTENSIVE COMPLICATIONS 121
2. THE CONTROL OF EXCESSIVE BLOOD PRESSURES UNDER
STRESS 124
2.1. STATEMENT OF PROBLEM 124
2.2. REQUIREMENTS OF ANTIHYPERTENSIVE THERAPY 125
3. ANTIHYPERTENSIVE EFFECT OF BETA-BLOCKING DRUGS . . .127
3.1. COMPARISON OF ATENOLOL/NADOLOL AND METOPROLOL . .127
3.1.1. PATIENTS AND METHODS 128
3.1.2. EFFECT 2,8 AND 24 HOURS AFTER LAST ORAL DOSING . . . .128
3.2. COMPARISON OF PINDOLOL, METOPROLOL AND
ACEBUTOLOL 138
3.2.1. PATIENTS AND METHODS 138
3.2.2. EFFECT DURING SUSTAINED SUBMAXIMAL AND MAXIMAL
EXERTION 141
3.2.3. EFFECT OF LONG-TERM TREATMENT FOR 12-16 MONTHS . . . 142
TABLE OF CONTENTS XVII
4. ANTIHYPERTENSIVE EFFECT OF DIURETICS COMPARED WITH
BETA-BLOCKING DRUGS AND THEIR COMBINATIONS . . . .145
4.1. COMPARISON OF HYDROCHLOROTHIAZIDE/AMILORIDE
HYDROCHLORIDE AND ACEBUTOLOL 145
4.1.1. PATIENTS AND METHODS 145
4.1.2. COMPARISON OF MONOTHERAPIES 146
4.1.3. EFFICACY OF THE COMBINATION 146
4.2. COMPARISON OF MEFRUSIDE AND ACEBUTOLOL 149
4.2.1. PATIENTS AND METHODS 150
4.2.2. COMPARISON OF MONOTHERAPIES 153
4.2.3. EFFECT ON MYOCARDIAL OXYGEN CONSUMPTION 161
4.3. FIXED COMBINATION OF TIMOLOL AND
HYDROCHLOROTHIAZIDE/AMILORIDE HYDROCHLORIDE . . .161
4.3.1. PATIENTS AND METHODS 162
4.3.2. BLOOD PRESSURE AND HEART RATE RESPONSES 163
4.4. FIXED COMBINATION OF ACEBUTOLOL AND MEFRUSIDE IN
MILD HYPERTENSIVES WITH CORONARY DISEASE 166
4.4.1. PATIENTS AND METHODS 166
4.4.2. BLOOD PRESSURE AND HEART RATE RESPONSES 168
4.4.3. EFFECT ON MYOCARDIAL OXYGEN CONSUMPTION AND
ST-SEGMENT DEPRESSION 168
5. ANTIHYPERTENSIVE EFFECT OF VASODILATORS COMPARED
WITH BETABLOCKERS AND THEIR COMBINATIONS 168
5.1.1. PATIENTS AND METHODS 168
5.1.2. COMPARISON OF MONOTHERAPIES 168
5.1.3. EFFICACY OF THE FREE COMBINATION 171
5.1.4. EFFECT ON MYOCARDIAL OXYGEN CONSUMPTION 172
5.2. COMPARISON OF NIFEDIPINE, NITRENDIPINE AND
ACEBUTOLOL 173
5.2.1. PATIENTS AND METHODS 173
5.2.2. COMPARISON OF MONOTHERAPIES 174
5.2.3. EFFICACY OF THE FREE COMBINATION 176
5.2.4. EFFICACY DURING BICYCLE ERGOMETRY AND DURING
ISOMETRIC EXERCISE 176
6. SUMMARY AND CONCLUSIONS REGARDING BETA BLOCKERS,
DIURETICS AND VASODILATORS 181
6.1. EFFICACY AND SIDE-EFFECTS OF BETA-BLOCKING DRUGS . . 181
6.2. CARDIOPROTECTIVE EFFECT OF BETA-BLOCKING DRUGS . . .185
6.3. IMPORTANCE OF COMBINED BETA BLOCKER-DIURETIC
THERAPY 186
6.4. EVALUATION OF MONOTHERAPY AND COMBINED
THERAPY 188
6.5. CONCLUSIONS 189
XVIII
TABLE OF CONTENTS
7. BETA-BLOCKING DRUGS AND DIURETICS FOR THE TREATMENT
OF HYPERTENSION IN THE ELDERLY 190
7.1. FIXED COMBINATION OF METIPRANOLOL AND BUTIZIDE . . .190
7.1.1. PATIENTS AND METHODS 190
7.1.2. BLOOD PRESSURE AND HEART RATE RESPONSES 190
7.2. FIXED COMBINATION OF TIMOLOL AND
HYDROCHLOROTHIAZIDE/AMILORIDE HYDROCHLORIDE . . . 192
7.2.1. PATIENTS 192
7.2.2. BLOOD PRESSURE RESPONSES 195
7.2.3. ECG FINDINGS 195
7.2.4. MYOCARDIAL OXYGEN CONSUMPTION AND ERGOMETRIC
STRESS TOLERANCE 196
7.2.5. SIDE-EFFECTS 197
7.3. SUMMARY AND CONCLUSIONS 198
8. ANTIHYPERTENSIVE EFFECT OF WEIGHT REDUCTION AND
ENDURANCE TRAINING 201
8.1. PATIENTS AND METHODS 201
8.2. BLOOD PRESSURE AND HEART RATE RESPONSES 202
8.3. EFFECT ON MYOCARDIAL OXYGEN CONSUMPTION 204
8.4. SUMMARY AND CONCLUSIONS 204
8.4.1. IMPORTANCE OF WEIGHT REDUCTION AND ENDURANCE
TRAINING 204
8.4.2. COMPARISON OF WEIGHT REDUCTION AND DRUG THERAPY . 206
IV. REFERENCES 207
V SUBJECT INDEX 225
|
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spelling | Franz, Ingomar-Werner Verfasser (DE-588)128909471 aut Ergometrie bei Hochdruckkranken Ergometry in hypertensive patients implications for diagnosis and treatment Ingomar-Werner Franz. Transl. by Terry Telger. Foreword by P. Schölmerich Ergometrische Untersuchungen zur Diasgnostik und Therapiekontrolle bei der arteriellen Hypertonie Berlin ; Heidelberg ; New York ; Tokyo Springer 1986 XVIII, 228 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Dt. Ausg. u.d.T.: Franz, Ingomar-Werner: Ergometrie bei Hochdruckkranken. - Mit Berlin, Freie Univ., Habil.-Schr. 1981 u.d.T.: Franz, Ingomar-Werner: Ergometrische Untersuchungen zur Diasgnostik und Therapiekontrolle bei der arteriellen Hypertonie Ergometrie (DE-588)4015248-0 gnd rswk-swf Hypertonie (DE-588)4026372-1 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Hypertonie (DE-588)4026372-1 s Ergometrie (DE-588)4015248-0 s DE-604 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022070379&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Franz, Ingomar-Werner Ergometry in hypertensive patients implications for diagnosis and treatment Ergometrie (DE-588)4015248-0 gnd Hypertonie (DE-588)4026372-1 gnd |
subject_GND | (DE-588)4015248-0 (DE-588)4026372-1 (DE-588)4113937-9 |
title | Ergometry in hypertensive patients implications for diagnosis and treatment |
title_alt | Ergometrie bei Hochdruckkranken Ergometrische Untersuchungen zur Diasgnostik und Therapiekontrolle bei der arteriellen Hypertonie |
title_auth | Ergometry in hypertensive patients implications for diagnosis and treatment |
title_exact_search | Ergometry in hypertensive patients implications for diagnosis and treatment |
title_full | Ergometry in hypertensive patients implications for diagnosis and treatment Ingomar-Werner Franz. Transl. by Terry Telger. Foreword by P. Schölmerich |
title_fullStr | Ergometry in hypertensive patients implications for diagnosis and treatment Ingomar-Werner Franz. Transl. by Terry Telger. Foreword by P. Schölmerich |
title_full_unstemmed | Ergometry in hypertensive patients implications for diagnosis and treatment Ingomar-Werner Franz. Transl. by Terry Telger. Foreword by P. Schölmerich |
title_short | Ergometry in hypertensive patients |
title_sort | ergometry in hypertensive patients implications for diagnosis and treatment |
title_sub | implications for diagnosis and treatment |
topic | Ergometrie (DE-588)4015248-0 gnd Hypertonie (DE-588)4026372-1 gnd |
topic_facet | Ergometrie Hypertonie Hochschulschrift |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022070379&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT franzingomarwerner ergometriebeihochdruckkranken AT franzingomarwerner ergometryinhypertensivepatientsimplicationsfordiagnosisandtreatment AT franzingomarwerner ergometrischeuntersuchungenzurdiasgnostikundtherapiekontrollebeiderarteriellenhypertonie |