Respiratory physiology of newborn mammals: a comparative perspective
Gespeichert in:
1. Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Baltimore [u.a.]
Hopkins Univ. Press
2001
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XVI, 344 S. Ill. |
ISBN: | 0801864976 |
Internformat
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Datensatz im Suchindex
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adam_text | Respiratory Physiology
of Newborn Mammals
A Comparative Perspective
Jacopo P Mortola, M D
Professor, Department of Physiology
McGill University
Montreal, Quebec, Canada
The Johns Hopkins University Press
Baltimore and London „ „ «, „ , ,
Contents
Preface xi
Abbreviations xiii
Introduction 1
Chapter 1 Gestation and Birth 4
The Respiratory System before Birth 8
Fetal Pulmonary Fluid 10 / Fetal Breathing Movements 15
Birth 18
What Controls the Onset of Continuous Breathing at Birth? 18 /
Birth, a Hyperoxic Event 21 / Mechanics of the First Breath 2 4 /
Establishment of the Functional Residual Capacity 33 /
Implications for Pulmonary Circulation 37
Interspecies Comparisons 41
Clinical Implications 42
Summary 42
Chapter 2 Metabolic and Ventilatory Requirements 45
Oxygen Consumption and Carbon Dioxide Production 45
The Metabolic Curve in Newborns 51 / The Mouse-to-Elephant
Metabolic Curve: What Does It Really Mean? 53
Pulmonary Ventilation 58
Mechanical Events in the First Hours after Birth 58 / Pulmonary
Ventilation and the Breathing Pattern 65 / Dead Space and Alveolar
Ventilation 70
Coupling of Ventilation and Metabolism 74
Interspecies Comparisons 76
viii Contents
Clinical Implications 78
Summary 79
Chapter 3 Mechanical Behavior of the
Respiratory Pump 80
The Respiratory Muscles 80
Mass and Fiber Type 81 / Fatigue and Fatigue Resistance 8 3 /
Blood Perfusion 85 / Mechanical Properties 86
The Newborn Thorax 89
Mechanical Interaction between Lungs and Chest Wall 91
Terminology 92 / Mechanical Properties of the Lungs 93 /
Mechanical Properties of the Chest Wall 100 / Static Coupling
between Lungs and Chest Wall 109 / Resistance to Airflow 111/
Being Very Srriall: The Case of Newborn Marsupials 115
The Active Mechanical Behavior 116
Inspiration 116 / Expiration 118
Energetics 123
Interspecies Comparisons 126
Clinical Implications 126
Summary 127
Chapter 4 Reflex Control of the Breathing Pattern 129
Reflex Control of Breath Amplitude and Duration 129
Load Compensation in Newborns 131 / Vagal Reflexes 135 /
Airway Receptors 144 / Vagal Control and Hypoxia 151
Ventilatory Reflexes of Extrapulmonary Origin 152
Upper Airway Reflexes 152 / Somatic and Chest Wall Reflexes 160
Central Organization of Respiratory Neurons 161
Breathing during Feeding 164
Interspecies Comparisons 167
Clinical Implications 167
Summary 168
Chapter 5 Changes in Temperature and Respiratory
Gases 171
Changes in Ambient or Body Temperature 171
Metabolic and Behavioral Responses 172 / Ventilatory Control
at Different Temperatures 183
Contents
O2 and CO2 Chemoreception 185
Peripheral Chemoreceptors 186 / Central Chemosensitivity 191
Changes in Oxygenation 193
O2 Transport 193 / Prenatal Hypoxia 197 / Acute Neonatal
Hypoxia 201 / Chronic Neonatal Hypoxia 216 / Hyperoxia 222
Hypercapnia 224
Acute Conditions 224 / Chronic Conditions 227 / Conditions
Confronting Burrowing Mammals 228
Interspecies Comparisons 229
Clinical Implications 230
Summary 231
Appendix A Passive Respiratory Mechanics:
Some Applications to Measurements
in Newborns 235
Artificial Ventilation 236
Compliance 236 / Resistance 237
Spontaneous Breathing 238
Compliance 238 / Time Constant and Resistance 241
Appendix B Comparisons and Normalization 243
Normalization 243
Allometry 245
Allometric Relationships of Newborn Mammals 250
Appendix C Orders and Suborders of the
Class Mammalia 251
Glossary 253
References Cited 269
Index 335
|
any_adam_object | 1 |
author | Mortola, Jacopo P. |
author_facet | Mortola, Jacopo P. |
author_role | aut |
author_sort | Mortola, Jacopo P. |
author_variant | j p m jp jpm |
building | Verbundindex |
bvnumber | BV026404833 |
ctrlnum | (OCoLC)633616693 (DE-599)BVBBV026404833 |
dewey-full | 573.219 |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 573 - Specific physiological systems in animals |
dewey-raw | 573.219 |
dewey-search | 573.219 |
dewey-sort | 3573.219 |
dewey-tens | 570 - Biology |
discipline | Biologie |
format | Book |
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indexdate | 2024-07-09T23:11:18Z |
institution | BVB |
isbn | 0801864976 |
language | English |
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physical | XVI, 344 S. Ill. |
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spelling | Mortola, Jacopo P. Verfasser aut Respiratory physiology of newborn mammals a comparative perspective Jacopo P. Mortola Baltimore [u.a.] Hopkins Univ. Press 2001 XVI, 344 S. Ill. txt rdacontent n rdamedia nc rdacarrier Respiration cabt Newborn Animals cabt HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021979858&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Mortola, Jacopo P. Respiratory physiology of newborn mammals a comparative perspective Respiration cabt Newborn Animals cabt |
title | Respiratory physiology of newborn mammals a comparative perspective |
title_auth | Respiratory physiology of newborn mammals a comparative perspective |
title_exact_search | Respiratory physiology of newborn mammals a comparative perspective |
title_full | Respiratory physiology of newborn mammals a comparative perspective Jacopo P. Mortola |
title_fullStr | Respiratory physiology of newborn mammals a comparative perspective Jacopo P. Mortola |
title_full_unstemmed | Respiratory physiology of newborn mammals a comparative perspective Jacopo P. Mortola |
title_short | Respiratory physiology of newborn mammals |
title_sort | respiratory physiology of newborn mammals a comparative perspective |
title_sub | a comparative perspective |
topic | Respiration cabt Newborn Animals cabt |
topic_facet | Respiration Newborn Animals |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021979858&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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