Immune modulation by infectious agents:
Gespeichert in:
| Weitere Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Jena
Fischer
1987
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| Ausgabe: | 1. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | 315 S. 41 Ill. u. graph. Darst. |
| ISBN: | 3334000338 |
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| 245 | 1 | 0 | |a Immune modulation by infectious agents |c ed. by Wolfgang Zschiesche. With contributions by J. Denner ... |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Jena |b Fischer |c 1987 | |
| 300 | |a 315 S. |b 41 Ill. u. graph. Darst. | ||
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| 700 | 1 | |a Zschiesche, Wolfgang |4 edt | |
| 700 | 1 | |a Denner, Joachim |e Sonstige |4 oth | |
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Datensatz im Suchindex
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| adam_text | PREFACE
13
ABBREVIATIONS 14
1. ENHANCEMENT AND SUPPRESSION OF IMMUNE RESPONSIVENESS BY BACTERIA,
BACTERIAL PRODUCTS AND EXTRACTS
(H. FINGER AND C. H.WIRSING VON KONIG) 16
1.1. INTRODUCTION 16
1.2. HISTORICAL NOTE 17
1.3. GRAM-NEGATIVE BACTERIA 18
1.3.1. ADJUVANT ACTIVITY OF WHOLE ORGANISMS AND CRUDE EXTRACTS 18
1.3.2. ADJUVANT ACTIVITY OF BORDETELLA PERTUSSIS ORGANISMS 19
1.3.2.1. INFLUENCE OF BORDETELLA PERTUSSIS ORGANISMS ON THE PRODUCTION
OF SERUM
ANTIBODY AND ON ANAPHYLACTIC SENSITIVITY 19
1.3.2.2. INFLUENCE OF BORDETELLA PERTUSSIS ORGANISMS ON NON-SPECIFIC
RESISTANCE
TO INFECTIONS 22
1.3.2.3. INFLUENCE OF BORDETELLA PERTUSSIS ORGANISMS ON THE PRIMARY AND
SECONDARY
ANTIBODY RESPONSE TO HETEROLOGOUS ERYTHROCYTES WITH SPECIAL REFERENCE
TO THE CELLULAR KINETICS 22
1.3.2.4. EFFECTS OF BORDETELLA PERTUSSIS ORGANISMS GIVEN ALONE 23
1.3.2.5. EFFECTS OF BORDETELLA PERTUSSIS ORGANISMS ON THE PRIMARY IMMUNE
RESPONSE
TO SRBC, WHEN INJECTED SIMULTANEOUSLY 25
1.3.2.6. EFFECTS OF BORDETELLA PERTUSSIS ORGANISMS ON THE SECONDARY
IMMUNE RES
PONSE TO SRBC, WHEN INJECTED SIMULTANEOUSLY 29
1.3.2.7. INFLUENCE OF BORDETELLA PERTUSSIS ORGANISMS ON THE
PARTICIPATION OF PERI
PHERAL LYMPH NODES IN THE PRIMARY AND SECONDARY IMMUNE RESPONSES TO
SRBC, WHEN INJECTED SIMULTANEOUSLY 30
1.3.2.8. INFLUENCE OF BORDETELLA PERTUSSIS ORGANISMS ON THE
ANTIBODY-FORMING PO
TENTIAL OF OLDER MICE 32
1.3.2.9. INFLUENCE OF BORDETELLA PERTUSSIS ORGANISMS ON THE
ANTIBODY-FORMING PO
TENTIAL OF THE NEWBORN 37
1.3.2.10. INFLUENCE OF BORDETELLA PERTUSSIS ORGANISMS ON THE
ANTIBODY-FORMING PO
TENTIAL UNDER SPECIAL CONDITIONS 37
1.3.2.11. IMPORTANCE OF TIMING OF BORDETELLA PERTUSSIS INJECTION IN
RELATION TO THE
INJECTION OF THE ANTIGEN 41
1.3.3. IMMUNOSUPPRESSIVE ACTIVITY 44
1.4. MYCOBACTERIA 45
1.4.1. ADJUVANT ACTIVITY OF MYCOBACTERIUM BOVIS STRAIN BCG 46
1.4.2. ACTIVATION OF ADHERENT CELLS (MACROPHAGES) BY MYCOBACTERIUM BOVIS
STRAIN BCG 47
1.4.3. ADJUVANT ACTIVITY OF BCG ON CELLULAR AND HUMORAL IMMUNE RESPONSES
. 48
1.4.4. IMMUNOSUPPRESSIVE ACTIVITY OF BCG 48
1.4.5. ALTERATION OF NON-SPECIFIC RESISTANCE TO INFECTION AFTER
TREATMENT WITH
MYCOBACTERIUM BOVIS STRAIN BCG 49
1.4.6. INFECTION WITH MYCOBACTERIUM BOVIS STRAIN BCG AS AN
IMMUNOMODULATOR
IN MALIGNANT DISEASES 50
1.4.7. OTHER EFFECTS OF INFECTION WITH MYCOBACTERIUM BOVIS STRAIN BCG
.... 51
HTTP://D-NB.INFO/870871447
8
CONTENTS
1.5. OTHER GRAM-POSITIVE BACTERIA 51
1.5.1. PROPIONIBACTERIUM ACNES AND RELATED SPECIES 52
1.5.1.1. ADJUVANT ACTIVITY OF PROPIONIBACTERIUM ACNES 52
1.5.1.2. ACTIVATION OF THE MONONUCLEAR PHAGOCYTE SYSTEM BY
PROPIONIBACTERIUM
ACNES 53
1.5.1.3. ACTIVATIES OF PROPIONIBACTERIUM ACNES ON THE CELLULAR AND
HUMORAL IM
MUNE RESPONSE 53
1.5.1.4. NON-SPECIFIC RESISTANCE TO INFECTION AFTER PRETREATMENT WITH
KILLED PRO
PIONIBACTERIUM ACNES 55
1.5.1.5. MODULATION OF RESISTANCE TO MALIGNANT TUMORS BY
PROPIONIBACTERIUM
ACNES 56
1.5.1.6. OTHER EFFECTS OF THE INJECTION OF PROPIONIBACTERIUM ACNES 57
1.5.2. LISTERIA MONOCYTOGENES 57
1.6. STRUCTURAL COMPONENTS AND PRODUCTS 58
1.6.1. ENDOTOXINS 58
1.6.1.1. ADJUVANT ACTIVITY OF ENDOTOXINS 59
1.6.1.2. SUPPRESSIVE ACTIVITY OF LIPOPOLYSACCHARIDES 62
1.6.2. PEPTIDOGLYCANS 64
1.6.2.1. ADJUVANT AND IMMUNOSUPPRESSIVE ACTIVITY OF BACTERIAL
PEPTIDOGLYCANS . . 64
1.6.2.2. INFLAMMATORY AND CYTOTOXIC ACTIVITIES OF BACTERIAL
PEPTIDOGLYCANS ... 65
1.6.2.3. OTHER EFFECTS OF BACTERIAL PEPTIDOGLYCANS 66
1.6.3. MURAMYL DIPEPTIDE AND ITS ANALOGUES 66
1.6.3.1. IMMUNOADJUVANT AND IMMUNOSUPPRESSIVE ACTIVITIES OF MURAMYL
DIPEPTIDE 67
1.6.3.2. ALTERATION OF MACROPHAGE ACTIVITY BY MURAMYL DIPEPTIDE 68
1.6.3.3. NON-SPECIFIC RESISTANCE TO INFECTION INDUCED BY MURAMYL
DIPEPTIDE 69
1.6.3.4. OTHER EFFECTS OF MURAMYL DIPEPTIDE AND ITS ANALOGUES 70
1.6.4. DIMYCOLIC ESTERS OF TREHALOSE (CORD FACTOR) 71
1.6.4.1. ADJUVANT AND IMMUNOSUPPRESSIVE ACTIVITY OF CORD FACTOR 71
1.6.4.2. OTHER EFFECTS OF TREHALOSE DIMYCOLATE 72
1.6.5. BORDETELLA PERTUSSIS TOXIN AND BORDETELLA PERTUSSIS MITOGEN 72
1.6.5.1. ADJUVANT ACTIVITY 72
1.6.5.2. IMMUNOSUPPRESSIVE ACTIVITY 75
1.6.6. OUTER MEMBRANE PROTEINS OF OTHER GRAM-NEGATIVE BACTERIA 75
1.6.7. MYCOPLASMA ARTHRITIDIS PRODUCTS 76
1.6.8. L-ASPARAGINASE 76
1.6.9. CHOLERA ENTEROTOXIN 77
1.7. MODE OF ACTION OF BACTERIAL IMMUNOMODULATORS 77
REFERENCES 84
2. STIMULATION AND SUPPRESSION OF IMMUNE RESPONSIVENESS BY VIRUSES
(W. ZSCHIESCHE, B. F. SEMENOV, AND J. DENNER ) 114
2.1. INTRODUCTION 114
2.2. VIRUS-INDUCED MODULATION OF IMMUNE RESPONSIVENESS IN EXPERIMENTAL
ANIMALS 114
2.2.1. ADENOVIRIDAE 115
2.2.2. HERPESVIRIDAC 115
2.2.3. IRIDOVIRIDAE 117
2.2.4. PARVOVIRIDAE 117
2.2.5. POXVIRIDAE 118
2.2.6. ARENAVIRIDAE 118
2.2.7. BUNYAVIRIDAE 120
2.2.8.
CORONAVIRIDAE 120
2.2.9. ORTHOMYXOVIRIDAE 121
2.2.10. PARAMYXOVIRIDAE 121
2.2.11. PICORNAVIRIDAE 123
1
AUTHOR OF THE CHAPTER 2.5.
CONTENTS
9
2.2.12. REOVIRIDAE 123
2.2.13. RETROVRIRIDAE (NON-ONCOGENIC) 124
2.2.14. RHABDOVIRIDAE 124
2.2.15. TOGAVIRIDAE 125
2.3. MODULATION OF IMMUNE RESPONSIVENESS IN HUMANS BY VIRAL INFECTIONS
AND
VACCINATION 129
2.3.1. INFECTIONS WITH HERPESVIRUSES 129
2.3.1.1. INFECTIONS WITH HSV-1 AND HSV-2 129
2.3.1.2. VARICELLA AND HERPES ZOSTER 130
2.3.1.3. CYTOMEGALOVIRUS INFECTION 130
2.3.1.4. INFECTIOUS MONONUCLEOSIS 131
2.3.2. ACUTE AND CHRONIC VIRAL HEPATITIS 132
2.3.3. INFECTIONS WITH CALICIVIRUSES 132
2.3.4. INFECTION WITH INFLUENZA VIRUS 133
2.3.5. MEASLES, MEASLES VACCINATION, AND RESPIRATORY SYNCYTIAL VIRUS
INFECTION . 133
2.3.6. INFECTIONS WITH TOGAVIRIDAE 135
2.3.6.1. TICK-BORNE ENCEPHALITIS 135
2.3.6.2. JAPANESE ENCEPHALITIS 135
2.3.6.3. OTHER FLAVIVIRUSES 135
2.3.6.4. RUBELLA 135
2.4. MODULATION BY VIRUSES OF RESISTANCE TO NONRELATED PATHOGENS ....
136
2.5. IMMUNOSUPPRESSION BY ONCOGENIC RETROVIRIDAE 140
2.5.1. AVIAN RETROVIRUSES 140
2.5.2. MURINE RETROVIRUSES 141
2.5.3. FELINE RETROVIRUSES 144
2.5.4. IMMUNOSUPPRESSION BY RETROVIRAL PROTEINS 144
2.5.5. ACQUIRED IMMUNODEFICIENCY SYNDROMES OF ANIMALS AND MAN 149
2.5.6. GENERAL CONSIDERATIONS ON THE MECHANISM OF RETROVIRUS-LNDUCED
IMMU
NOSUPPRESSION 154
2.6. CHARACTERISTIC FEATURES OF VIRUS-INDUCED IMMUNE MODULATION 156
2.6.1. INFLUENCE OF VIRUS DOSE 156
2.6.2. INFLUENCE OF VIRULENCE 157
2.6.3. INFLUENCE OF ROUTE OF INFECTION 157
2.6.4. GENETIC INFLUENCE ON VIRUS-INDUCED IMMUNE MODULATION 157
2.6.5. FHENOTYPES OF VIRUS-INDUCED IMMUNE MODULATION 158
2.7. MECHANISMS OF VIRUS-INDUCED NONSPECIFIC MODULATION OF IMMUNE
RESPON
SIVENESS 159
2.7.1. VIRUS-INDUCED DYSFUNCTION OF CELLS OF THE MONONUCLEAR PHAGOCYTIC
SYSTEM 159
2.7.1.1. ALTERATION OF ANTIGEN HANDLING BY MACROPHAGES 159
2.7.1.2. MODULATION OF LYMPHOCYTE PROLIFERATION BY VIRUS-INFECTED
MACROPHAGES 161
2.7.1.3. STIMULATION OR ENHANCEMENT OF SECRETION OF SOLUBLE FACTORS OF
MACRO
PHAGES 161
2.7.1.4. IMPAIRMENT OF CHEMOTACTIC ACTIVITY OF MACROPHAGES 162
2.7.1.5. ANTIBODY-MEDIATED ENHANCEMENT OF VIRAL INFECTIONS 162
2.7.2. VIRUS-INDUCED ALTERATIONS OF LYMPHOCYTE FHYSIOLOGY 163
2.7.2.1. PERIPHERAL LYMPHOCYTOPENIA 163
2.7.2.2. ALTERATION OF LYMPHOCYTE TRAPPING 164
2.7.3. VIRAL EFFECTS ON HELPER CELLS, SUPPRESSOR CELLS, AND NK CELLS AND
THEIR
FUNCTIONS 165
2.7.3.1. VIRUS-INDUCED DYSFUNCTION OF HELPER CELLS 165
2.7.3.2. VIRAL INDUCTION OF NONSPECIFIC SUPPRESSOR CELLS 166
2.7.3.3. VIRUS-INDUCED DYSFUNCTION OR ELIMINATION OF SUPPRESSOR T
LYMPHOCYTES . . 167
2.7.3.4. ALTERATIONS OF NK ACTIVITY BY VIRUSES 163
2.7.4. VIRUS-INDUCED PRODUCTION OF EFFECTOR LYMPHOKINES INVOLVED IN
IMMUNE
RESPONSE 168
2.7.4.1. INTERFERONS 169
2.7.4.2. MIGRATION INHIBITORY FACTORS 170
2.7.4.3. CHEMOTACTIC FACTORS 171
10
CONTENTS
2.7.4.4. CYTOTOXIC FACTORS 171
2.7.5. VIRUS-INDUCED DYSFUNCTION OF CELLS OF THE MYELOPOIETIC SYSTEM 172
2.7.6. VIRAL EFFECTS ON THE COMPLEMENT SYSTEM 172
2.7.7. IMMUNE MODULATORY PROPERTIES OF VIRAL PROTEINS 173
2.7.8. IMMUNE MODULATION OF IMMUNE COMPLEXES APPEARING IN THE COURSE OF
VIRAL INFECTION 173
2.7.9. AUTOIMMUNITY AND IMMUNE MODULATION 174
2.7.10. ROLE OF INFECTION OF LYMPHORETICULAR CELLS IN VIRUS-INDUCED
IMMUNE MO
DULATION 175
2.8. CONCLUDING REMARKS 176
REFERENCES 178
3. MODULATION OF THE IMMUNE RESPONSE BY PARASITIC INFECTIONS
(M. J. DOENHOFF) 202
3.1. INTRODUCTION 202
3.2. COMPLEXITIES IN THE GENETIC BASIS TO CONTROL OF HOST-PARASITE
INTERACTIONS 203
3.2.1. INNATE IMMUNITY 203
3.2.2. ACQUIRED IMMUNITY 204
3.3. MECHANISMS OF EVADING THE IMMUNE RESPONSE 205
3.3.1. ANTIGEN VARIATION AND ANTIGEN SHEDDING 205
3.3.2. ACQUISITION OF HOST ANTIGENS AND ANTIGENIC MIMICRY 206
3.3.3. ANTIGENIC SECLUSION AND ENCYSTMENT 207
3.3.4. BLOCKING ANTIGENS AND CIRCULATING IMMUNE COMPLEXES 208
3.3.5. INFECTION OF IMMUNE-DEPRESSED HOSTS 209
3.4. PARASITE-INDUCED IMMUNOSUPPRESSION 209
3.4.1. THE EFFECT ON CONCURRENT INFECTIONS 210
3.4.2. MALARIA-INDUCED IMMUNOSUPPRESSION 211
3.4.3. TRYPANOSOME-LNDUCED IMMUNOSUPPRESSION 212
3.4.4. IMMUNOSUPPRESSION INDUCED BY OTHER PROTOZOAN AND HELMINTH
INFECTIONS . 213
3.5. MECHANISMS OF PARASITE-INDUCED IMMUNOSUPPRESSION 214
3.5.1. HISTOLOGICAL DISRUPTION OF LYMPHOID ORGANS AND NUMERICAL CHANGES
IN
IMMUNOCOMPETENT CELLS 214
3.5.2. ELEVATED IMMUNOGLOBULIN CONCENTRATIONS, POLYCLONAL LYMPHOCYTE
ACTIVA
TION AND AUTOIMMUNITY 214
3.5.3. FUNCTIONAL IMPAIRMENT OF IMMUNO-REACTIVE CELLS 216
3.5.4. PARASITE-INDUCED GENERATION OF SUPPRESSOR CELL ACTIVITY 217
3.5.5. PRODUCTION OF IMMUNOSUPPRESSIVE FACTORS BY PARASITES 218
3.6. PARASITE-MEDIATED IMMUNOPOTENTIATION 219
3.7. CONCLUSION 220
REFERENCES 220
4. AUTOIMMUNITY TRIGGERED BY INFECTIOUS AGENTS
(W. ZSCHIESCHE AND B. F. SEMENOV) 236
4.1. THE IMMUNOLOGICAL BASIS OF AUTOTOLERANCE 236
4.2. AUTOIMMUNITY 237
4.2.1. DEFINITION AND CRITERIA 237
4.2.2. MECHANISMS OF FORMATION OF AUTOIMMUNITY 238
4.2.2.1. EXPOSURE OF NEW ANTIGENS 238
4.2.2.2. CROSS-REACTIVE ANTIGENS 238
4.2.2.3. ALLOGENEIC EFFECT 239
4.2.2.4. POLYCLONAL ACTIVATION OF B LYMPHOCYTES 239
4.2.2.5. LOSS OF SUPPRESSOR CELLS 239
4.3. AUTOANTIBODIES 240
4.3.1. AUTOANTIBODIES IN NORMAL INDIVIDUALS 240
4.3.2. AUTOANTIBODIES IN INFECTIOUS DISEASES 240
4.3.2.1. RHEUMATOID FACTORS 240
4.3.2.2. THYMO- AND LYMPHOCYTOTOXIC ANTIBODIES 241
CONTENTS 11
4.3.2.3. ANTI-SMOOTH-MUSCLE ANTIBODIES 242
4.3.2.4. ANTI-NUCLEAR ANTIBODIES 242
4.3.2.5. ANTI-ERYTHROCYTE ANTIBODIES 243
4.3.2.6. PATHOGENETIC SIGNIFICANCE OF AUTOANTIBODIES 243
4.4. AUTOIMMUNITY AND VIRUSES 244
4.4.1. AUTOIMMUNE REACTIONS TRIGGERED BY VIRUSES 244
4.4.1.1. EXPOSURE OF NEW ANTIGENS AS POSSIBLE SOURCE OF VIRUS-TRIGGERED
AUTO
IMMUNE REACTIONS 244
4.4.1.1. POLYCLONAL B LYMPHOCYTE STIMULATION AS POSSIBLE SOURCE OF
VIRUS-TRIGGERED
AUTOIMMUNE REACTIONS 246
4.4.1.3. NONSPECIFIC CYTOTOXICITY AS POSSIBLE SOURCE OF VIRUS-TRIGGERED
AUTO
IMMUNITY 248
4.4.1.4. CROSS-REACTIVE ANTIGENS AS POSSIBLE SOURCE OF VIRUS-TRIGGERED
AUTO
IMMUNITY 249
4.4.1.5. VIRUS-INDUCED ANTI-HOST CELL ACTIVITY AS POSSIBLE SOURCE OF
AUTOIMMUNE
RESPONSE 251
4.4.1.6. AUTOANTIBODIES AND AUTOIMMUNE REACTIONS DURING VIRAL DISEASES .
. . 251
4.4.2. DISEASES WITH AUTOIMMUNE CHARACTER POSSIBLY TRIGGERED BY VIRUSES
. . . 253
4.4.2.1. HEPATITIS B AND CHRONIC ACTIVE HEPATITIS 253
4.4.2.2. DIABETES MELLITUS 257
4.4.2.3. HUMAN SYSTEMIC LUPUS ERYTHEMATOSUS AND RELATED SYNDROMES IN
ANIMALS 259
4.4.2.4. EQUINE INFECTIOUS ANEMIA 270
4.4.2.5. ALEUTIAN DISEASE OF MINK 271
4.5. AUTOIMMUNITY AND BACTERIA 272
4.5.1. AUTOIMMUNE REACTIONS TRIGGERED BY BACTERIA 272
4.5.1.1. NEW ANTIGENS AS POSSIBLE SOURCE OF BACTERIA-TRIGGERED
AUTOIMMUNE
REACTIONS 272
4.5.1.2. POLYCLONAL B CELL ACTIVATION AS POSSIBLE SOURCE OF
BACTERIA-TRIGGERED AUTO
IMMUNE REACTIONS 272
4.5.1.3. CROSS-REACTIVE ANTIGENS AS POSSIBLE SOURCE OF
BACTERIA-TRIGGERED AUTO
IMMUNE REACTIONS 274
4.5.1.4. AUTOANTIBODIES AND AUTOIMMUNE REACTIONS DURING BACTERIAL
INFECTIONS 276
4.5.2. DISEASES WITH AUTOIMMUNE CHARACTER POSSIBLY TRIGGERED BY BACTERIA
277
4.5.2.1. POST-STREPTOCOCCAL DISEASES 277
4.5.2.2. NONSPECIFIC INFLAMMATORY BOWEL DISEASE 278
4.6. AUTOIMMUNITY AND PROTOZOA 279
4.6.1. AUTOIMMUNE REACTIONS TRIGGERED BY PROTOZOA 280
4.6.1.1. POLYCLONAL LYMPHOCYTE STIMULATION AS POSSIBLE SOURCE OF
PROTOZOA-INDUCED
AUTOIMMUNE REACTIONS 280
4.6.1.2. CROSS-REACTIVE ANTIGENS AS POSSIBLE SOURCE OF PROTOZOA-INDUCED
AUTO
IMMUNITY 280
4.6.1.3. AUTOANTIBODIES AND AUTOIMMUNE REACTIONS DURING PROTOZOAN
DISEASES 280
4.6.2. DISEASES WITH AUTOIMMUNE CHARACTER POSSIBLY TRIGGERED BY PROTOZOA
. 282
4.7. AUTOIMMUNE REACTIONS AND VACCINATION 282
4.8. CONCLUDING REMARKS 283
4.8.1. AUTOIMMUNITY AS TRANSIENT DYSFUNCTION OF IMMUNE REACTIVITY 284
4.8.2. AUTOIMMUNITY AS NOSOLOGICAL COMPLEX 285
REFERENCES 285
SUBJECT INDEX 308
|
| any_adam_object | 1 |
| author2 | Zschiesche, Wolfgang |
| author2_role | edt |
| author2_variant | w z wz |
| author_facet | Zschiesche, Wolfgang |
| building | Verbundindex |
| bvnumber | BV025873799 |
| classification_rvk | YD 1200 |
| ctrlnum | (OCoLC)246967757 (DE-599)BVBBV025873799 |
| discipline | Medizin |
| edition | 1. ed. |
| format | Book |
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| id | DE-604.BV025873799 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:14:07Z |
| institution | BVB |
| isbn | 3334000338 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-019121007 |
| oclc_num | 246967757 |
| open_access_boolean | |
| owner | DE-11 |
| owner_facet | DE-11 |
| physical | 315 S. 41 Ill. u. graph. Darst. |
| publishDate | 1987 |
| publishDateSearch | 1987 |
| publishDateSort | 1987 |
| publisher | Fischer |
| record_format | marc |
| spelling | Immune modulation by infectious agents ed. by Wolfgang Zschiesche. With contributions by J. Denner ... 1. ed. Jena Fischer 1987 315 S. 41 Ill. u. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Immunreaktion (DE-588)4133841-8 gnd rswk-swf Infektion (DE-588)4161650-9 gnd rswk-swf Infektion (DE-588)4161650-9 s Immunreaktion (DE-588)4133841-8 s DE-604 Zschiesche, Wolfgang edt Denner, Joachim Sonstige oth DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019121007&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Immune modulation by infectious agents Immunreaktion (DE-588)4133841-8 gnd Infektion (DE-588)4161650-9 gnd |
| subject_GND | (DE-588)4133841-8 (DE-588)4161650-9 |
| title | Immune modulation by infectious agents |
| title_auth | Immune modulation by infectious agents |
| title_exact_search | Immune modulation by infectious agents |
| title_full | Immune modulation by infectious agents ed. by Wolfgang Zschiesche. With contributions by J. Denner ... |
| title_fullStr | Immune modulation by infectious agents ed. by Wolfgang Zschiesche. With contributions by J. Denner ... |
| title_full_unstemmed | Immune modulation by infectious agents ed. by Wolfgang Zschiesche. With contributions by J. Denner ... |
| title_short | Immune modulation by infectious agents |
| title_sort | immune modulation by infectious agents |
| topic | Immunreaktion (DE-588)4133841-8 gnd Infektion (DE-588)4161650-9 gnd |
| topic_facet | Immunreaktion Infektion |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019121007&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT zschieschewolfgang immunemodulationbyinfectiousagents AT dennerjoachim immunemodulationbyinfectiousagents |