Bioorganic chemistry: a chemical approach to enzyme action
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Springer
1989
|
| Ausgabe: | 2. ed. |
| Schriftenreihe: | Springer advanced texts in chemistry
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Literaturverz. S. 597 - 638 |
| Beschreibung: | XV, 651 S. 90 Ill. u. graph. Darst. |
| ISBN: | 3540967958 0387967958 |
Internformat
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Datensatz im Suchindex
| _version_ | 1805082913192017920 |
|---|---|
| adam_text |
CONTENTS
SERIES PREFACE
V
"
PREFACE TO THE FIRST EDITION IX
PREFACE TO THE SECOND EDITION XI
CHAPTER 1
INTRODUCTION TO BIOORGANIC CHEMISTRY 1
1.1 BASIC CONSIDERATIONS 1
1.2 PROXIMITY EFFECTS IN ORGANIC CHEMISTRY 4
1.3 MOLECULAR ADAPTATION 8
1.4 MOLECULAR RECOGNITION AND THE SUPRAMOLECULAR LEVEL 17
CHAPTER
2
BIOORGANIC CHEMISTRY OF AMINO ACIDS AND POLYPEPTIDES 23
2.1 CHEMISTRY OF THE LIVING CELLS 24
2.2 ANALOGY BETWEEN ORGANIC REACTIONS AND BIOCHEMICAL
TRANSFORMATIONS 27
2.3 CHEMISTRY OF THE PEPTIDE BOND 36
2.4 NONRIBOSOMAL PEPTIDE BOND FORMATION 44
2.5 ASYMMETRIC SYNTHESIS OF A-AMINO ACIDS 52
2.6 ASYMMETRIC SYNTHESIS WITH CHIRAL ORGANOMETALLIC CATALYSTS 78
2.7 TRANSITION STATE ANALOGS 80
2.8 ANTIBODIES AS ENZYMES 85
2.9 CHEMICAL MUTATIONS 89
2.10 MOLECULAR RECOGNITION AND DRUG DESIGN 96
HTTP://D-NB.INFO/890540225
XIV
CONTENTS
CHAPTER 3
BIOORGANIC CHEMISTRY OF THE PHOSPHATE GROUPS AND POLYNUCLEOTIDES 110
3.1 BASIC CONSIDERATIONS 110
3.2 ENERGY STORAGE 112
3.3 HYDROLYTIC PATHWAYS AND PSEUDOROTATION 123
3.4 DNA INTERCALANTS 140
3.5 CHEMICAL EVOLUTION OF BIOPOLYMERS 154
3.6 RNA MOLECULES AS CATALYSTS 164
CHAPTER 4
ENZYME CHEMISTRY 171
4.1 INTRODUCTION TO CATALYSIS 171
4.2 INTRODUCTION TO ENZYMES 183
4.3 MULTIFUNCTIONAL CATALYSIS AND SIMPLE MODELS 193
4.4 A-CHYMOTRYPSIN 196
4.5 OTHER HYDROLYTIC ENZYMES 216
4.6 STEREOELECTRONIC CONTROL IN HYDROLYTIC REACTIONS 222
4.7 IMMOBILIZED ENZYMES AND ENZYME TECHNOLOGY 242
4.8 ENZYMES IN SYNTHETIC ORGANIC CHEMISTRY 248
4.9 ENZYME-ANALOG-BUILT POLYMERS 252
4.10 DESIGN OF MOLECULAR CLEFTS 256
CHAPTER 5
ENZYME MODELS 262
5.1 HOST-GUEST COMPLEXATION CHEMISTRY 265
5.2 NEW DEVELOPMENTS IN CROWN ETHER CHEMISTRY 287
5.3 MEMBRANE CHEMISTRY AND MICELLES 323
5.4 POLYMERS 342
5.5 CYCLODEXTRINS 350
5.6 ENZYME DESIGN USING STEROID TEMPLATE 366
5.7 REMOTE FUNCTIONALIZATION REACTIONS 371
5.8 BIOMIMETIC POLYENE CYCLIZATIONS 383
CHAPTER 6
METAL IONS 398
6.1 METAL IONS IN PROTEINS AND BIOLOGICAL MOLECULES 398
6.2 CARBOXYPEPTIDASE A AND THE ROLE OF ZINC 400
CONTENTS
XV
6.3 HYDROLYSIS OF AMINO ACID ESTERS AND AMIDES AND
PEPTIDES 408
6.4 IRON AND OXYGEN TRANSPORT 416
6.5 COPPER ION 446
6.6 BIOMODELS OF PHOTOSYNTHESIS AND ENERGY TRANSFER 456
6.7 COBALT AND VITAMIN B12 ACTION 468
CHAPTER 7
COENZYME CHEMISTRY 489
7.1 OXIDOREDUCTION 490
7.2 PYRIDOXAL PHOSPHATE 527
7.3 SUICIDE ENZYME INACTIVATORS AND AFFINITY LABELS 548
7.4 THIAMINE PYROPHOSPHATE 563
7.5 BIOTIN 577
REFERENCES 597
INDEX 639 |
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| author | Dugas, Hermann |
| author_facet | Dugas, Hermann |
| author_role | aut |
| author_sort | Dugas, Hermann |
| author_variant | h d hd |
| building | Verbundindex |
| bvnumber | BV025863211 |
| classification_rvk | VK 8500 |
| ctrlnum | (OCoLC)721895996 (DE-599)BVBBV025863211 |
| discipline | Chemie / Pharmazie |
| edition | 2. ed. |
| format | Book |
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| id | DE-604.BV025863211 |
| illustrated | Illustrated |
| indexdate | 2024-07-20T07:40:13Z |
| institution | BVB |
| isbn | 3540967958 0387967958 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-019110843 |
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| physical | XV, 651 S. 90 Ill. u. graph. Darst. |
| publishDate | 1989 |
| publishDateSearch | 1989 |
| publishDateSort | 1989 |
| publisher | Springer |
| record_format | marc |
| series2 | Springer advanced texts in chemistry |
| spelling | Dugas, Hermann Verfasser aut Bioorganic chemistry a chemical approach to enzyme action Hermann Dugas 2. ed. New York [u.a.] Springer 1989 XV, 651 S. 90 Ill. u. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Springer advanced texts in chemistry Literaturverz. S. 597 - 638 Enzymkatalyse (DE-588)4152480-9 gnd rswk-swf Enzym (DE-588)4014988-2 gnd rswk-swf Naturstoff (DE-588)4041418-8 gnd rswk-swf Biochemie (DE-588)4006777-4 gnd rswk-swf Naturstoffchemie (DE-588)4171332-1 gnd rswk-swf Naturstoffchemie (DE-588)4171332-1 s DE-604 Enzym (DE-588)4014988-2 s Biochemie (DE-588)4006777-4 s Naturstoff (DE-588)4041418-8 s Enzymkatalyse (DE-588)4152480-9 s DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019110843&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Dugas, Hermann Bioorganic chemistry a chemical approach to enzyme action Enzymkatalyse (DE-588)4152480-9 gnd Enzym (DE-588)4014988-2 gnd Naturstoff (DE-588)4041418-8 gnd Biochemie (DE-588)4006777-4 gnd Naturstoffchemie (DE-588)4171332-1 gnd |
| subject_GND | (DE-588)4152480-9 (DE-588)4014988-2 (DE-588)4041418-8 (DE-588)4006777-4 (DE-588)4171332-1 |
| title | Bioorganic chemistry a chemical approach to enzyme action |
| title_auth | Bioorganic chemistry a chemical approach to enzyme action |
| title_exact_search | Bioorganic chemistry a chemical approach to enzyme action |
| title_full | Bioorganic chemistry a chemical approach to enzyme action Hermann Dugas |
| title_fullStr | Bioorganic chemistry a chemical approach to enzyme action Hermann Dugas |
| title_full_unstemmed | Bioorganic chemistry a chemical approach to enzyme action Hermann Dugas |
| title_short | Bioorganic chemistry |
| title_sort | bioorganic chemistry a chemical approach to enzyme action |
| title_sub | a chemical approach to enzyme action |
| topic | Enzymkatalyse (DE-588)4152480-9 gnd Enzym (DE-588)4014988-2 gnd Naturstoff (DE-588)4041418-8 gnd Biochemie (DE-588)4006777-4 gnd Naturstoffchemie (DE-588)4171332-1 gnd |
| topic_facet | Enzymkatalyse Enzym Naturstoff Biochemie Naturstoffchemie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019110843&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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