Developmental biology:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Sunderland, Mass.
Sinauer
1991
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| Ausgabe: | 3. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XX, 891 S. Ill. |
| ISBN: | 0878932453 |
Internformat
MARC
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| 100 | 1 | |a Gilbert, Scott F. |d 1949- |e Verfasser |0 (DE-588)133098559 |4 aut | |
| 245 | 1 | 0 | |a Developmental biology |
| 250 | |a 3. ed. | ||
| 264 | 1 | |a Sunderland, Mass. |b Sinauer |c 1991 | |
| 300 | |a XX, 891 S. |b Ill. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
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Datensatz im Suchindex
| _version_ | 1804141311258787840 |
|---|---|
| adam_text | Developmental
Biology TIM!® I ID)nT n © M
Leon W Browder ©msM
Carol A Erickson Buck
William R Jeffery
• -Se -r T ; *• O*
r • ft,-- •
Saunders College Publishmg
Philadelphia Toronto
Ft Worth London
Chicago Sydney
San Francisco Tokyo
Montreal
PART I Introduction 1
1 The Origins of Developmental Biology 2
PART II Gametogenesis 21
2 Spermatogenesis 22
3 Oogenesis 54
PART III From Sperm and Egg to
Embryo 125
4 Fertilization: The Activation of Development 126
5 Cleavage: Becoming Multicellular 162
6 Initiating the Embryonic Body Plan: Embryonic
Polarization and Gastrulation 196
PART IV Organizing the Multicellular
Embryo 241
7 Laying Down the Vertebrate Body Plan: The Gen
eration of Ectodermal Organ Rudiments 242
8 Laying Down the Vertebrate Body Plan: Meso
dermal and Endodermal Organ Rudiments 291
9 The Cellular Basis of Morphogenesis 326
PART V Genetic Regulation of
Development 393
10 Genome Constancy and its Implications for
Development 394
11 The Progressive Determination of Cell Fate 426
12 The Role of Induction in Determination of Cell
Fate 477
13 Maternal and Zygotic Control During the Initia
tion of Development 540
Contents
Overview
xi
PART VI The Organized Generation of
Cell Diversity 577
14 Establishment of Spatial Patterns of Gene Expres
sion During Development 578
15 Organogenesis: Limb Development 625
16 Organogenesis: Gonad Development and Sex
Differentiation 661
17 Organogenesis: Development of the Eye 684
18 The Molecular Biology of Cell
Differentiation 722
APPENDIX: Techniques of Molecular
Biology A-l
GLOSSARY G-l
INDEX 1-1
PART
Introduction 1
1 The Origins of Developmental
Biology 2
1-1 Germ Cells: Bridging the Generation Gap 4
1-2 The Roux-Weismann Theory 6
1-3 The Mendelian Era 8
1-4 Embryology: Losing the Faith 12
1-5 Genetics: Keeping the Faith 14
1-6 The Modern Era 16
1-7 Chapter Synopsis 18
References 18
PART II
Gametogenesis 21
2 Spermatogenesis 27
SECTIONONE
Overview of Gametogenesis 23
Essay: Meiosis 24
SECTIONTWO
Spermatogenesis 26
2-1 Sperm Structure 28
Mammalian Sperm 29
Primitive Sperm 34
2-2 Germ Cell-Somatic Cell Interactions in Spermatogenesis
2-3 Hormonal Regulation of Spermatogenesis 37
2-4 Spermiogenesis 39
Nuclear Modifications 39
Formation of Sperm Organelles 42
Cell Surface Changes During Spermatogenesis 45
2-5 Gene Function in Spermatogenesis 46
2-6 Spermiation 47
2-7 Mammalian Sperm Maturation 47
2-8 Chapter Synopsis 49
References 50
3 Oogenesis 54
3-1 Oocyte-Accessory Cell Interactions During Oogenesis 56
The Mammalian Follicle 57
The Insect Egg Chamber 58
3-2 Organization of the Egg and Differentiation of Oocyte
Constituents 65
Mitochondria and Germ Plasm 66
Yolk 68
The Egg Cortex 76
The Oocyte Nucleus 77
Cytoplasmic Membranes 77
3-3 Gene Expression During Oogenesis: Amphibians 78
Lampbrush Chromosomes 79
Synthesis and Accumulation of mRNA 87
Localization of mRNA 88
Synthesis of Ribosome Components 90
Transfer RNA Synthesis 96
3-4 Gene Expression During Oogenesis: Nonamphibian Species 97
Drosophila 97
Sea Urchins 99
The Mouse 99
3-5 Utilization of Genomic Information in Oogenesis:
Conclusions 101
3-6 Hormonal Control of Oogenesis 101
3-7 Conversion of the Oocyte to the Egg: Maturation and
Ovulation 106
Regulation of Maturation and Ovulation 106
The Role of Maturation Promotion Factor 108
Molecular Events in Amphibian Oocyte Maturation 112
The Consequences of Germinal Vesicle Breakdown 113
Ovulation 114
3-8 Egg Envelopes 115
3-9 Chapter Synopsis 115
References 117
PART 111
From Sperm and Egg to
Embryo 125
4 Fertilization: The Activation of
Development 126
4-1 Sperm and Egg Structure 127
4-2 Setting the Stage for Fertilization: Events That Occur Before
Sperm-Egg Fusion 129
Activation of Sperm Motility 129
Attraction of Sperm to the Egg 131
Sperm Penetration of the Egg Surface Coats 132
Essay: Advances in the Regulation of Human Fertility: Immuno-
contraception and in vitro Fertilization 136
4-3 Fusion of Sperm and Egg 139
4-4 The Response to Fertilization: Events that Occur after Sperm-
Egg Fusion 142
Prevention of Polyspermy 142
Control of the Cortical Reaction 148
Fusion of Sperm and Egg Nuclei 149
4-5 The Initiation of Development 152
4-6 Parthenogenesis 155
4-7 Chapter Synopsis 156
References 157
5 Cleavage: Becoming
Multicellular 162
5-1 Cleaving Embryos Have Modified Cell Cycles 163
5-2 What is the Mechanism of Cleavage? 165
5-3 How is Cytokinesis Regulated? 168
The Asters Regulate Cleavage Furrow Formation 169
The Asters Induce the Cleavage Furrow by Signaling the
Cortex 170
5-4 Patterns of Cleavage 172
Types of Cleavage 172
Radial Cleavage 173
Bilateral Cleavage 176
Rotational Cleavage 182
Spiral Cleavage 185
Superficial Cleavage 188
5-5 Classifying Animals According to Cleavage Patterns 190
5-6 Chapter Synopsis 193
References 193
6 Initiating the Embryonic Body Plan:
Embryonic Polarization and
Gastrulation 196
6-1 Embryonic Polarization 198
Polarization of the Amphibian Embryo 198
Polarization of the Drosophila Embryo 205
6-2 Gastrulation and Establishment of the Embryonic Body
Plan 209
Basic Cell Movements of Gastrulation 210
Gastrulation and Formation of the Body Plan in
Invertebrates 212
Gastrulation and Formation of the Body Plan in
Chordates 224
Essay: Cell Movements During Xenopus Gastrulation 228
6-3 The Primary Organizer 234
6-4 Chapter Synopsis 235
References 235
PART
Organizing the Multicellular
Embryo 241
7 Laying Down the Vertebrate Body
Plan: The Generation of Ectodermal
Organ Rudiments 242
7-1 Neurulation: Establishment of the Body Axis and Separation of
Ectoderm into Subpopulations 244
Amphibians 246
Chick 247
7-2 Mechanisms of Neurulation 249
Neural Plate Formation 249
Bending of the Neural Plate 250
7-3 Development of the Central Nervous System 252
Cell Derivatives of the Neural Ectoderm 252
Gross Morphology of the Early Central Nervous
System 255
Histological Differentiation of the Central Nervous
System 256
7-4 Development of the Peripheral Nervous System 260
Structure and Function of the Peripheral Nervous
System 260
Neural Crest Cells 264
Pathways of Neural Crest Cell Migration 268
Connections of Neurons with Their Targets 272
Essay: Growth Cone Guidance in Insects 276
Essay: Marking Neurons with Horseradish Peroxidase 280
7-5 Ectodermal Placodes 282
7-6 Epidermis and Cutaneous Appendages 284
7-7 Chapter Synopsis 286
References 287
8 Laying Down the Vertebrate Body
Plan: Mesodermal and Endodermal
Organ Rudiments 291
8-1 The Mesoderm 293
Paraxial Mesoderm—Trunk 294
Paraxial Mesoderm—Head 298
Intermediate Mesoderm 300
Lateral Plate Mesoderm 303
8-2 The Endoderm 309
Pharynx 309
Digestive Tube and Associated Glands 311
Respiratory Organs 311
8-3 The Extraembryonic Membranes 313
Chick Extraembryonic Membranes 313
Human Placenta 316
8-4 Chapter Synopsis 323
References 324
9 The Cellular Basis of
Morphogenesis 326
9-1 Morphogenetic Movements 328
Mode s of Epithelial Morphogenesis 328
Modes of Individual Cell Movement 330
9-2 The Cytoskeletal Components 334
Microtubules 334
Microfilaments 337
Intermediate Filaments 339
9-3 Organization of Cytoskeletal Elements in Epithelia and
Fibroblasts 340
Role of Cytoskeleton in Epithelial Folding 340
Distribution of the Cytoskeleton in Fibroblasts 342
Essay: Visualization of the Cytoskeleton by Immunofluorescence
Microscopy 344
9-4 Cell Motility in the Embryo 349
9-5 Cell-Matrix Adhesions 353
Collagen 354
Proteoglycans 354
Adhesive Glycoproteins 357
Cell Adhesion Receptors 357
9-6 Control of Directional Migration 359
Determination of Migratory Pathways 359
Control of Directionality of Migration 361
Essay: The Role of the Extracellular Matrix in Neural Crest Cell
Migration 362
9-7 Intercellular Adhesion 366
Specific Cellular Adhesiveness 368
Differential Adhesion Hypothesis 369
Molecular Basis of Sorting Out 370
9-8 Cell Death and Cell Proliferation 378
Cell Death in the Nematode 379
Essay: Roles of Oncogenes in Controlling Cell Proliferation 380
-Cell Proliferation 384
9-9 Conclusions ~ 384—
9-10 Chapter Synopsis 384
References 385
PARTr
Genetic Regulation of
Development 393
10 Genome Constancy and Its
Implications for Development 394
10-1 Functional Analyses of Genome Equivalence 395
Nuclear Transplantation: Amphibians 396
Nuclear Transplantation: Mammals 404
10-2 Integrity of the Genome During Development 409
10-3 Differential Gene Expression 409
Essay: Exceptions to the Gene Constancy Rule 410
10-4 Nucleocytoplasmic Interactions 417
10-5 Chapter Synopsis 421
References 421
11 The Progressive Determination of
Cell Fate 426
11-1 Methods of Studying Cell Determination 427
Fate Maps 427
How is Cell Determination Assayed? 430
11-2 Mosaic and Regulative Embryos 432
11-3 Regulation of Cell Determination by Ooplasmic
Determinants 436
Germ Cell Determination 436
Somatic Cell Determination 448
11-4 What is an Ooplasmic Determinant? 460
11-5 Regulation of Cell Determination by Extrinsic Factors 467
Extrinsic Determination of Trophectoderm and Inner Cell
Mass in Mammals 467
Cell Position and Gradients in Sea Urchin
Development 469
11-6 Chapter Synopsis 471
References 472
12 The Role of Induction in
Determination of Cell Fate 477
12-1 Mesoderm Induction in Amphibians 478
12-2 Determination of the Central Nervous System 485
Regional Determination by the Chordamesoderm 486
What is the Nature of the Neural Inducer? 493
Primary Organizers in Higher Vertebrates 495
12-3 Secondary Induction 496
Instructive Versus Permissive Interactions 497
Induction Across Species Boundaries: The Role of the
Ectodermal Genome 506
Nature of the Inductive Interaction 509
What Are the Inducing Molecules? 512
Role of Induction in Morphogenesis: Branching of
Glands 521
12-4 Signaling and Pattern 526
The Role of Specific Genes in Patterning 533
12-5 Chapter Synopsis 533
References 534
13 Maternal and Zygotic Control
During the Initiation of
Development 540
13-1 Maternal Control of Early Development 541
13-2 Activation of Protein Synthesis 545
Mechanism of Translational Activation after
Fertilization 546
Maternal Control of Translational Activation 551
Mechanisms of Translational Suppression in the
Unfertilized Egg 555
13-3 Specific Translational Control During Early
Development 558
13-4 Zygotic Control of Development 561
Activation of Transcription 563
The Switch from Oogenic to Zygotic mRNA
Translation 565
13-5 Control of Transcriptional Activation 567
13-6 Chapter Synopsis 570
References 571
PART VI
The Organized Generation of
Cell Diversity 577
14 Establishment of Spatial Patterns
of Gene Expression During
Development 578
14-1 Region-Specific Gene Expression in the Sea Urchin
Embryo 579
Essay: Gene Organization and Regulation of Transcription 582
14-2 Gene Expression Controlling Segmentation in Drosophila 589
Imaginal Discs and Transdetermination 590
Homeotic Mutations and Segmentation 593
The Coordinate Genes Determine the Anteroposterior
Axis 596
The Segmentation Genes Divide the Embryo into
__ Segments 598
Regulation of the Segmentation Genes 602
Segmentation Genes Encode DNA-Binding Proteins that
Modulate Transcription 604
The Homeotic Selector Genes Specify Segment Identity 606
14-3 Regional Patterns of Gene Expression During Early Develop
ment in Vertebrates 610
Xenopus 610
Mammals 615
14-4 Chapter Synopsis 620
References 620
15 Organogenesis: Limb
Development 625
15-1 The Vertebrate Limb as a Developmental System 626
15-2 The Chick Limb: Illustration of Principles for Limb
Development 626
Early Outgrowth of the Limb 627
Limb Outgrowth Involves Reciprocal Interactions Between
the Ectoderm and Mesoderm 628
15-3 Establishment of Axes in the Chick Limb 630
Establishment of the Proximodistal Axis 633
The Anteroposterior Axis of the Limb: A Simple Gradient of
Retinoic Acid 636
Determination of the Dorsoventral Axis 640
15-4 Establishment of Tissue Types Within the Limb 641
Determination of Cell Types Within the Limb 641
15-5 Regeneration of the Urodele Limb 642
The Source and Role of Blastemal Cells 645
Regulation of Regeneration 647
Restoration of the Pattern of Cell Differentiation 648
15-6 Chapter Synopsis 656
References 657
16 Organogenesis: Gonad Development
and Sex Differentiation 661
16-1 Development of the Vertebrate Gonads 662
16-2 Sex Ducts and External Genitalia 665
16-3 Sex Determination 667
Control of Mammalian Sex Determination 668
Secondary Sex Characteristics 671
16-4 Origin of the Primordial Germ Cells 674
Chick Germ Cell Migration 674
Mammalian Germ Cell Migration 677
Amphibian Germ Cell Migration 678
16-5 Chapter Synopsis 680
References 681
17 Organogenesis: Development of
the Eye 684
17-1 Early Morphogenetic Events 685
17-2 The Cornea: Progressive Development Correlated with
Changes in Extracellular Matrix 688
17-3 The Sclera: Connective Tissue Covering of the Eye 692
17-4 The Iris: Composite of Retina and Neural Crest 693
17-5 Origin and Development of the Lens 695
17-6 The Neural Retina 699
Essay: Techniques for Tracing Cell Lineage 703
17-7 Retinotectal Projection 704
Pathfinding Along the Optic Tract 705
Synapse with the Tectum 706
Regeneration Experiments 707
Developing Systems: Molecular Basis of Chemoaffinity 710
Retinotectal Patterning Mechanisms in Addition to
Chemoaffinity 712
Summing up 716
17-8 Chapter Synopsis 717
References 718
18 The Molecular Biology of Cell
Differentiation 722
Essay: Eukaryotic Transcription Regulatory Proteins 724
18-1 Immunoglobulin Gene Expression 725
Essay: Vertebrate Immunoglobulin Gene Rearrangement During
Lymphocyte Differentiation 726
18-2 Muscle-Specific Gene Transcription 731
Essay: DNA Methylation 732
18-3 Regulation of Transcription by Vertebrate Steroid
Hormones 740
18-4 Globin Gene Switching 744
18-5 Chapter Synopsis 748
18-6 Conclusions 749
References 750
APPENDIX
Techniques of Molecular
Biology A-l
I Electrophoresis A-l
Gel Electrophoresis of Nucleic Acids A-l
SDS-Gel Electrophoresis A-2
Two-Dimensional Gel Electrophoresis of Proteins A-3
II DNA Renaturation A-3
III RNArDNA Hybridization A-6
IV cDNA A-7
V Recombinant DNA A-7
Construction of Gene Libraries A-ll
Probing a Library A-12
VI Analyses of Cloned Genes A-14
Restriction Mapping A-14
DNA Sequencing A-15
VII Southern Blotting A-17
VIII Northern Blotting (RNA Blot
Analysis) A-17
IX Polymerase Chain Reaction
(PCR) A-17
X Transgenic Animals A-19
References A-20
Glossary G-l
Index 1-1
|
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| id | DE-604.BV025858633 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:13:51Z |
| institution | BVB |
| isbn | 0878932453 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-019106416 |
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| physical | XX, 891 S. Ill. |
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| publishDateSearch | 1991 |
| publishDateSort | 1991 |
| publisher | Sinauer |
| record_format | marc |
| spelling | Gilbert, Scott F. 1949- Verfasser (DE-588)133098559 aut Developmental biology 3. ed. Sunderland, Mass. Sinauer 1991 XX, 891 S. Ill. txt rdacontent n rdamedia nc rdacarrier Entwicklungsphysiologie (DE-588)4152449-4 gnd rswk-swf Embryologie (DE-588)4014562-1 gnd rswk-swf Embryologie (DE-588)4014562-1 s DE-604 Entwicklungsphysiologie (DE-588)4152449-4 s HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019106416&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gilbert, Scott F. 1949- Developmental biology Entwicklungsphysiologie (DE-588)4152449-4 gnd Embryologie (DE-588)4014562-1 gnd |
| subject_GND | (DE-588)4152449-4 (DE-588)4014562-1 |
| title | Developmental biology |
| title_auth | Developmental biology |
| title_exact_search | Developmental biology |
| title_full | Developmental biology |
| title_fullStr | Developmental biology |
| title_full_unstemmed | Developmental biology |
| title_short | Developmental biology |
| title_sort | developmental biology |
| topic | Entwicklungsphysiologie (DE-588)4152449-4 gnd Embryologie (DE-588)4014562-1 gnd |
| topic_facet | Entwicklungsphysiologie Embryologie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019106416&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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